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The map label for this gene is hrcA [H]

Identifier: 188526915

GI number: 188526915

Start: 105790

End: 106620

Strand: Reverse

Name: hrcA [H]

Synonym: HPSH_00560

Alternate gene names: 188526915

Gene position: 106620-105790 (Counterclockwise)

Preceding gene: 188526918

Following gene: 188526914

Centisome position: 6.63

GC content: 38.15

Gene sequence:

>831_bases
ATGGTGATTGACGAGATTTTTCAAATAATGATGTTAAAAAGAATTAAAGTAGGTTCTGATTTGAATAAAAAAGAGAGTTT
GTTAGATGCGTTTGTTAAAACCTATCTGCAGATTTTAGAACCCATTAGCTCTAAACGCTTAAAAGAGTTGGCAAACTTGA
AAATATCTTGCGCGACGATTAGGAATTATTTTCAAACCCTTTCTAAAGAGGGCATGCTCTATCAAGCCCATTCTAGCGGT
GCTAGATTGCCCACTTTTAAGGCGCTTGAAAACTATTGGCAAAAGTCGTTGCGCTTTGAAGTTTTAAGGGTAAATGAAAA
ACGCTTAAAAAGCGCGAGTGAAAATTTTGGGCTTTTTACGCTGTTAAAAAAACCGAGTTTGGAGCGTTTAGAAAGAGTCA
TTGAGTGCGAAAAACGCTTTTTGATTTTGGACTTTTTGGCGTTTTCTTGCGCGCTAGGTTACAGCGTTAAAATGGAGAAG
TTTTTATTAGAGCTTGTGGGTAGAAGCGTTAAAGAAGTGCGCTCAATCGCTGCTTCTGTCAATGCGTTGAGTTTGGCTAG
GCAATTAGAGCGCTTGGAGTATTCCAACACGCAAATCACGCGCTTTAATCTAATGGGGTTAAAAACGCTTTTAAACAGCC
CTTTATTTTTTGACATTTTAGGGGGTAAGGTTTTAGAGCGTTTGAAAAAAGGTTTGCATTTTATAGAGCCTGATTACATG
CTAGTAACGCGCCCTATAGAATTTCAAAACAAGCGGATGCAACTGCTTTGCGTGGGGAAATTGGAATGCGATTATGAAGG
GTTTTTTCAAACCATTTCTAAGGAGGAATAA

Upstream 100 bases:

>100_bases
TAAACTTTAAAGAAAAATCGGGTAATTTTTATCACTTTTTTAAAACAAGTGATAGATTATTAACTTTTTGCGCTATAATG
CGAGGGTTCTTTCATCAAGA

Downstream 100 bases:

>100_bases
TGAAAGATAAACACAACCAAGAACACGATCATTTAAGCCAAGAAGAGCCAGAGTCTTGCGAAAAGGCTTGCGCTTGCAAA
GAACAACAAGGTGAAGAAAT

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MVIDEIFQIMMLKRIKVGSDLNKKESLLDAFVKTYLQILEPISSKRLKELANLKISCATIRNYFQTLSKEGMLYQAHSSG
ARLPTFKALENYWQKSLRFEVLRVNEKRLKSASENFGLFTLLKKPSLERLERVIECEKRFLILDFLAFSCALGYSVKMEK
FLLELVGRSVKEVRSIAASVNALSLARQLERLEYSNTQITRFNLMGLKTLLNSPLFFDILGGKVLERLKKGLHFIEPDYM
LVTRPIEFQNKRMQLLCVGKLECDYEGFFQTISKEE

Sequences:

>Translated_276_residues
MVIDEIFQIMMLKRIKVGSDLNKKESLLDAFVKTYLQILEPISSKRLKELANLKISCATIRNYFQTLSKEGMLYQAHSSG
ARLPTFKALENYWQKSLRFEVLRVNEKRLKSASENFGLFTLLKKPSLERLERVIECEKRFLILDFLAFSCALGYSVKMEK
FLLELVGRSVKEVRSIAASVNALSLARQLERLEYSNTQITRFNLMGLKTLLNSPLFFDILGGKVLERLKKGLHFIEPDYM
LVTRPIEFQNKRMQLLCVGKLECDYEGFFQTISKEE
>Mature_276_residues
MVIDEIFQIMMLKRIKVGSDLNKKESLLDAFVKTYLQILEPISSKRLKELANLKISCATIRNYFQTLSKEGMLYQAHSSG
ARLPTFKALENYWQKSLRFEVLRVNEKRLKSASENFGLFTLLKKPSLERLERVIECEKRFLILDFLAFSCALGYSVKMEK
FLLELVGRSVKEVRSIAASVNALSLARQLERLEYSNTQITRFNLMGLKTLLNSPLFFDILGGKVLERLKKGLHFIEPDYM
LVTRPIEFQNKRMQLLCVGKLECDYEGFFQTISKEE

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002571
- InterPro:   IPR011991 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 32034; Mature: 32034

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIDEIFQIMMLKRIKVGSDLNKKESLLDAFVKTYLQILEPISSKRLKELANLKISCATI
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RNYFQTLSKEGMLYQAHSSGARLPTFKALENYWQKSLRFEVLRVNEKRLKSASENFGLFT
HHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCEEE
LLKKPSLERLERVIECEKRFLILDFLAFSCALGYSVKMEKFLLELVGRSVKEVRSIAASV
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NALSLARQLERLEYSNTQITRFNLMGLKTLLNSPLFFDILGGKVLERLKKGLHFIEPDYM
HHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCE
LVTRPIEFQNKRMQLLCVGKLECDYEGFFQTISKEE
EEECCHHHCCCCEEEEEEECCCCCHHHHHHHHCCCC
>Mature Secondary Structure
MVIDEIFQIMMLKRIKVGSDLNKKESLLDAFVKTYLQILEPISSKRLKELANLKISCATI
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RNYFQTLSKEGMLYQAHSSGARLPTFKALENYWQKSLRFEVLRVNEKRLKSASENFGLFT
HHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCEEE
LLKKPSLERLERVIECEKRFLILDFLAFSCALGYSVKMEKFLLELVGRSVKEVRSIAASV
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NALSLARQLERLEYSNTQITRFNLMGLKTLLNSPLFFDILGGKVLERLKKGLHFIEPDYM
HHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCE
LVTRPIEFQNKRMQLLCVGKLECDYEGFFQTISKEE
EEECCHHHCCCCEEEEEEECCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]