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The map label for this gene is bdlA [H]

Identifier: 188526888

GI number: 188526888

Start: 73889

End: 75910

Strand: Reverse

Name: bdlA [H]

Synonym: HPSH_00400

Alternate gene names: 188526888

Gene position: 75910-73889 (Counterclockwise)

Preceding gene: 188526889

Following gene: 188526881

Centisome position: 4.72

GC content: 39.22

Gene sequence:

>2022_bases
ATGAGATCTACAAGAATTGGTTCTAAAATTGTCATGATGGTGTGTGCGGTTGTCATTGCGATTAGTGCTGTTATGGGCGT
TATTATCAGCTACAAGGTTGAAAGCGTGTTGCAAAGCCAAGCCACAGAATTGCTGCAAAAAAAGGCTCAGTTAGTCAGTT
TCAAGATTCAAAGCATCATGAAGCGCATTTTTATTGGTGCTAACACCCTTGAAAAATTTTTAAGCGATGAAAATAGCACT
ATCAACGACACCCTAAAAAAGCGCATGCTCTCTGAGTTTTTGTTAGCAAACCCTCATGTGTTATTGATTAGCGCGATTTA
TACGGATAGTAATGAACGAATTATCACTGCTATGAATTTGGATTCAAAAATCGCCTACCCTAATACCACGCTCAATGAAA
CCATGACCAATCAAATCCGTTCGCTCAAAGATATAACCCCTTCAGATCCCTATTATAAAGAGGTTAATGGCAATAAAATC
TATGGCATGGATATTACCCTCCCCTTAATGGGTAAGAATCAAAAGACTATAGGCGCGCTGAATCTCTTTTTAAACATTGA
CGCTTTTTATACAGATGTGGTAGGCGAGAAAAAGAGCAACACCTTTTTAATGGGGAAAGATGGCAGGCTTTTAATCAACC
CTAATCATGAGATCCAAGATAAGATTTTAAGCGCTATCAATCCGGATAAAAGAGTCGCTAAAGCTGTGGAGTATTACAAT
CAAAACGAAGCGGGCACTTTGAGCTATCATTCATTGAGCGGGAATACAGAAACCTTTTTAGCCATACAGCCCTTTGATTT
TTTTGAAGAAAAAGGGGATAACGGCAACCAGTGGCGTTGGGCAATTGGGAAATATGTCAATAAATCTTTAGTCTTTAAAG
AAGCCACAAACACCAAATACATTATTATCACCACTTTGATTTTAGGCGTGCTGGTGTTAGCCCTTTTGGTCTTTATCATC
GTTTCTAGCCTTATAACCAAACGCATCGGTAGGGTCAATAACACCCTAAACGATTTTTTCAACTTGCTTAACAACCCCAA
AAATAACCACGCCATAAGCCTAACGCCCCCAAGCGCTTATGATGAAATCGGGCAAATGCAAGCTTCTATTAATGAAAACA
TTCTTAAAACCCAAAAAAGCATTCAAGCCGATAATCAAGCCATTCAAAACAGCATTGAAGTAACAAACCATGTGGAAAAT
GGGGATTTCACGCAAGAAATCGCATGCGTGCCTAAAAATAAAGATTTGCAAGCCCTAAGAAATACGATTAATAGCATTAT
CCAGTATTTTCGCAACCAAATTGGCGCCAATATTGAAGCCCTAAATAACGCCCTAGAGCATTATAAAAACCTGGATTTCA
CCCACCACATCCAAAACCCTAAAGCCAACATGGAAAAAGCGCTCAACACTTTAGGGCAAGAAATTTCTAGCATGCTTAAA
GCTTCTTTAGGGTTTGCAAACGCGCTCAATCATGAATCCAAAGATTTAAAAACTTGCGTGGATAACTTGACTAAAACCGC
TCACAAACAAGAAAGAAGCCTGAAAAACACCACTCAATCCTTAGAAGAAATCACTAATATTATCACAACAATTGATTCTA
AAAGCCAAGAGATGATCTCTCAAGGCGAAGACATTAAAAGCGTGGTGGATATGATTAGAGATATTGCCGATCAAACCAAT
CTTTTAGCCCTAAATGCCGCTATTGAAGCCGCACGGGCCGGTGAGCATGGCAGAGGCTTTGCGGTGGTGGCTGATGAAGT
GAGAAAGCTCGCTGAAAGGACGCAAAAATCGCTCAGCGAAATTGAAGCTAATATCAATATTTTAGTGCAAAGCATTGCCG
ATAACGCTGAGTCTATTAAAATGCAAAACAAGGGCGTAGAAAACATCCACAACTCCATTAACGCCTTGCAACAAGATATG
CAGGATAATTTGACTATCGCTAATCATTCTTTACAAGTCAGCACTAAAATTGATGGGATCTCCCAAGATATTTTAGAAGA
TGTGAGCAAGAAGAAATTTTAA

Upstream 100 bases:

>100_bases
TTTATTTTCTGCTTTTTTGTTCTCTCTTGTTTCATTAAAATTTCACAATAATTATGTATAATAATCGTTCTCTATCAATA
GTTTTAAAAGGGCAAAGGGA

Downstream 100 bases:

>100_bases
TTTTTAATTTTGAGCGTCTAAAATGTGAAACCGCCTAAAGGGCTTTTTATAAAGTGCCCTAAAAAACGCTAATGCGAAAG
TCTCTTTAAAAAACGTTTTT

Product: methyl-accepting chemotaxis transducer (tlpC)

Products: NA

Alternate protein names: Chemotaxis regulator BdlA [H]

Number of amino acids: Translated: 673; Mature: 673

Protein sequence:

>673_residues
MRSTRIGSKIVMMVCAVVIAISAVMGVIISYKVESVLQSQATELLQKKAQLVSFKIQSIMKRIFIGANTLEKFLSDENST
INDTLKKRMLSEFLLANPHVLLISAIYTDSNERIITAMNLDSKIAYPNTTLNETMTNQIRSLKDITPSDPYYKEVNGNKI
YGMDITLPLMGKNQKTIGALNLFLNIDAFYTDVVGEKKSNTFLMGKDGRLLINPNHEIQDKILSAINPDKRVAKAVEYYN
QNEAGTLSYHSLSGNTETFLAIQPFDFFEEKGDNGNQWRWAIGKYVNKSLVFKEATNTKYIIITTLILGVLVLALLVFII
VSSLITKRIGRVNNTLNDFFNLLNNPKNNHAISLTPPSAYDEIGQMQASINENILKTQKSIQADNQAIQNSIEVTNHVEN
GDFTQEIACVPKNKDLQALRNTINSIIQYFRNQIGANIEALNNALEHYKNLDFTHHIQNPKANMEKALNTLGQEISSMLK
ASLGFANALNHESKDLKTCVDNLTKTAHKQERSLKNTTQSLEEITNIITTIDSKSQEMISQGEDIKSVVDMIRDIADQTN
LLALNAAIEAARAGEHGRGFAVVADEVRKLAERTQKSLSEIEANINILVQSIADNAESIKMQNKGVENIHNSINALQQDM
QDNLTIANHSLQVSTKIDGISQDILEDVSKKKF

Sequences:

>Translated_673_residues
MRSTRIGSKIVMMVCAVVIAISAVMGVIISYKVESVLQSQATELLQKKAQLVSFKIQSIMKRIFIGANTLEKFLSDENST
INDTLKKRMLSEFLLANPHVLLISAIYTDSNERIITAMNLDSKIAYPNTTLNETMTNQIRSLKDITPSDPYYKEVNGNKI
YGMDITLPLMGKNQKTIGALNLFLNIDAFYTDVVGEKKSNTFLMGKDGRLLINPNHEIQDKILSAINPDKRVAKAVEYYN
QNEAGTLSYHSLSGNTETFLAIQPFDFFEEKGDNGNQWRWAIGKYVNKSLVFKEATNTKYIIITTLILGVLVLALLVFII
VSSLITKRIGRVNNTLNDFFNLLNNPKNNHAISLTPPSAYDEIGQMQASINENILKTQKSIQADNQAIQNSIEVTNHVEN
GDFTQEIACVPKNKDLQALRNTINSIIQYFRNQIGANIEALNNALEHYKNLDFTHHIQNPKANMEKALNTLGQEISSMLK
ASLGFANALNHESKDLKTCVDNLTKTAHKQERSLKNTTQSLEEITNIITTIDSKSQEMISQGEDIKSVVDMIRDIADQTN
LLALNAAIEAARAGEHGRGFAVVADEVRKLAERTQKSLSEIEANINILVQSIADNAESIKMQNKGVENIHNSINALQQDM
QDNLTIANHSLQVSTKIDGISQDILEDVSKKKF
>Mature_673_residues
MRSTRIGSKIVMMVCAVVIAISAVMGVIISYKVESVLQSQATELLQKKAQLVSFKIQSIMKRIFIGANTLEKFLSDENST
INDTLKKRMLSEFLLANPHVLLISAIYTDSNERIITAMNLDSKIAYPNTTLNETMTNQIRSLKDITPSDPYYKEVNGNKI
YGMDITLPLMGKNQKTIGALNLFLNIDAFYTDVVGEKKSNTFLMGKDGRLLINPNHEIQDKILSAINPDKRVAKAVEYYN
QNEAGTLSYHSLSGNTETFLAIQPFDFFEEKGDNGNQWRWAIGKYVNKSLVFKEATNTKYIIITTLILGVLVLALLVFII
VSSLITKRIGRVNNTLNDFFNLLNNPKNNHAISLTPPSAYDEIGQMQASINENILKTQKSIQADNQAIQNSIEVTNHVEN
GDFTQEIACVPKNKDLQALRNTINSIIQYFRNQIGANIEALNNALEHYKNLDFTHHIQNPKANMEKALNTLGQEISSMLK
ASLGFANALNHESKDLKTCVDNLTKTAHKQERSLKNTTQSLEEITNIITTIDSKSQEMISQGEDIKSVVDMIRDIADQTN
LLALNAAIEAARAGEHGRGFAVVADEVRKLAERTQKSLSEIEANINILVQSIADNAESIKMQNKGVENIHNSINALQQDM
QDNLTIANHSLQVSTKIDGISQDILEDVSKKKF

Specific function: Essential for biofilm dispersion by sensing environmental cues. May be involved in sensing and transducing signals within cells, resulting in the modulation of c-di-GMP levels, swimming motility and adhesiveness of the bacterial cell surface [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=157, Percent_Identity=37.5796178343949, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1789453, Length=206, Percent_Identity=30.0970873786408, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1788195, Length=281, Percent_Identity=28.4697508896797, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI2367378, Length=197, Percent_Identity=29.9492385786802, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1788194, Length=78, Percent_Identity=51.2820512820513, Blast_Score=79, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00015 MCPsignal; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 75056; Mature: 75056

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSTRIGSKIVMMVCAVVIAISAVMGVIISYKVESVLQSQATELLQKKAQLVSFKIQSIM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRIFIGANTLEKFLSDENSTINDTLKKRMLSEFLLANPHVLLISAIYTDSNERIITAMNL
HHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCEEEEEECC
DSKIAYPNTTLNETMTNQIRSLKDITPSDPYYKEVNGNKIYGMDITLPLMGKNQKTIGAL
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEECCCCEEEEEEEEEEECCCCCCHHHHE
NLFLNIDAFYTDVVGEKKSNTFLMGKDGRLLINPNHEIQDKILSAINPDKRVAKAVEYYN
EHEEECHHHHHHHHCCCCCCEEEEECCCEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHC
QNEAGTLSYHSLSGNTETFLAIQPFDFFEEKGDNGNQWRWAIGKYVNKSLVFKEATNTKY
CCCCCEEEEEEECCCCCEEEEECCHHHHHHCCCCCCCCHHHHHHHHCHHHEEEECCCCCE
IIITTLILGVLVLALLVFIIVSSLITKRIGRVNNTLNDFFNLLNNPKNNHAISLTPPSAY
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHH
DEIGQMQASINENILKTQKSIQADNQAIQNSIEVTNHVENGDFTQEIACVPKNKDLQALR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEECCCCCCHHHHH
NTINSIIQYFRNQIGANIEALNNALEHYKNLDFTHHIQNPKANMEKALNTLGQEISSMLK
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHH
ASLGFANALNHESKDLKTCVDNLTKTAHKQERSLKNTTQSLEEITNIITTIDSKSQEMIS
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
QGEDIKSVVDMIRDIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAERTQKSLSE
CCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHH
IEANINILVQSIADNAESIKMQNKGVENIHNSINALQQDMQDNLTIANHSLQVSTKIDGI
HHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEECCCEEEEECCCCH
SQDILEDVSKKKF
HHHHHHHHHHCCC
>Mature Secondary Structure
MRSTRIGSKIVMMVCAVVIAISAVMGVIISYKVESVLQSQATELLQKKAQLVSFKIQSIM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRIFIGANTLEKFLSDENSTINDTLKKRMLSEFLLANPHVLLISAIYTDSNERIITAMNL
HHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCEEEEEECC
DSKIAYPNTTLNETMTNQIRSLKDITPSDPYYKEVNGNKIYGMDITLPLMGKNQKTIGAL
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEECCCCEEEEEEEEEEECCCCCCHHHHE
NLFLNIDAFYTDVVGEKKSNTFLMGKDGRLLINPNHEIQDKILSAINPDKRVAKAVEYYN
EHEEECHHHHHHHHCCCCCCEEEEECCCEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHC
QNEAGTLSYHSLSGNTETFLAIQPFDFFEEKGDNGNQWRWAIGKYVNKSLVFKEATNTKY
CCCCCEEEEEEECCCCCEEEEECCHHHHHHCCCCCCCCHHHHHHHHCHHHEEEECCCCCE
IIITTLILGVLVLALLVFIIVSSLITKRIGRVNNTLNDFFNLLNNPKNNHAISLTPPSAY
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHH
DEIGQMQASINENILKTQKSIQADNQAIQNSIEVTNHVENGDFTQEIACVPKNKDLQALR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEECCCCCCHHHHH
NTINSIIQYFRNQIGANIEALNNALEHYKNLDFTHHIQNPKANMEKALNTLGQEISSMLK
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHH
ASLGFANALNHESKDLKTCVDNLTKTAHKQERSLKNTTQSLEEITNIITTIDSKSQEMIS
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
QGEDIKSVVDMIRDIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAERTQKSLSE
CCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHH
IEANINILVQSIADNAESIKMQNKGVENIHNSINALQQDMQDNLTIANHSLQVSTKIDGI
HHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEECCCEEEEECCCCH
SQDILEDVSKKKF
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]