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The map label for this gene is bioD [H]

Identifier: 188526839

GI number: 188526839

Start: 28710

End: 29366

Strand: Reverse

Name: bioD [H]

Synonym: HPSH_00145

Alternate gene names: 188526839

Gene position: 29366-28710 (Counterclockwise)

Preceding gene: 188526840

Following gene: 188526836

Centisome position: 1.83

GC content: 39.57

Gene sequence:

>657_bases
ATGCTCTTTATCAGCGCGACTAACACTAATGCCGGAAAAACCACATGCGCTAGGCTATTAGCCCAATATTGCAACGCTTG
TGGCGTTAGAACGATTCTATTAAAGCCCATTGAAACAGGCGTTAATGACACAACCAACCACTTTAGCGATGTGCATTTAT
TCTTGCAAGATAACCGCCTTTTAGATCGCTCTTTAACCTTAAAAGACATTTCATTCTATCGTTACGCTAAAGCTTCAGCC
CCTCTCATCGCCCAACAAGAAGAAAACCAAAACGCCCCTATTGACACGAATGATTTAATCCAACGCCTCCAAAATTTCAC
CAAAACTTACGATTTAGTCATCGTTGAAGGGGCTGGGGGGTTATGCGTGCCTATCACTTTAGAAGAAAACATGCTAGATC
TTGCCCTAAAACTAAAAGCCAAAATACTTGTGATTAGCCATGATAATTTGGGCTTGATTAATGATTGTTTGCTGAATGAT
TTTTTATTGAAATCCCACCAACTAGACTATAAAATCGCTATCAATTTGAGGGAAAACAACGCCGCTTTTCACAGCGTCAG
TTTGCCCTATATTGAGCTTTTTAACGAACGCTCCAATAACCCCATTGTGATTTTCCAACAAAGCCTAAAAGAATTAATGA
GCTTTGCTCTTAAATAA

Upstream 100 bases:

>100_bases
TATTTTAAGTTTCATTTTTGATAATGTGAAGTTGCCACAAACCAAAAATGCATTGACAGCTCAAATCTTTGATGGGGCGT
ATCAATTTAAAGGTTAAACC

Downstream 100 bases:

>100_bases
AGTGCAGACAGAGCTCACGCTGATAAAAAAGCCCATTAACAGCAAAGCGTATAAAATCCAGCTAAAAATGGGTTTTGAAA
TGTCAGCGCTCTCTTTTAAG

Product: dethiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MLFISATNTNAGKTTCARLLAQYCNACGVRTILLKPIETGVNDTTNHFSDVHLFLQDNRLLDRSLTLKDISFYRYAKASA
PLIAQQEENQNAPIDTNDLIQRLQNFTKTYDLVIVEGAGGLCVPITLEENMLDLALKLKAKILVISHDNLGLINDCLLND
FLLKSHQLDYKIAINLRENNAAFHSVSLPYIELFNERSNNPIVIFQQSLKELMSFALK

Sequences:

>Translated_218_residues
MLFISATNTNAGKTTCARLLAQYCNACGVRTILLKPIETGVNDTTNHFSDVHLFLQDNRLLDRSLTLKDISFYRYAKASA
PLIAQQEENQNAPIDTNDLIQRLQNFTKTYDLVIVEGAGGLCVPITLEENMLDLALKLKAKILVISHDNLGLINDCLLND
FLLKSHQLDYKIAINLRENNAAFHSVSLPYIELFNERSNNPIVIFQQSLKELMSFALK
>Mature_218_residues
MLFISATNTNAGKTTCARLLAQYCNACGVRTILLKPIETGVNDTTNHFSDVHLFLQDNRLLDRSLTLKDISFYRYAKASA
PLIAQQEENQNAPIDTNDLIQRLQNFTKTYDLVIVEGAGGLCVPITLEENMLDLALKLKAKILVISHDNLGLINDCLLND
FLLKSHQLDYKIAINLRENNAAFHSVSLPYIELFNERSNNPIVIFQQSLKELMSFALK

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=159, Percent_Identity=29.559748427673, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 24529; Mature: 24529

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFISATNTNAGKTTCARLLAQYCNACGVRTILLKPIETGVNDTTNHFSDVHLFLQDNRL
CEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEEEEHHHCCCCCCCCCCCEEEEEEECCEE
LDRSLTLKDISFYRYAKASAPLIAQQEENQNAPIDTNDLIQRLQNFTKTYDLVIVEGAGG
ECCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCEEEEEEEECCCC
LCVPITLEENMLDLALKLKAKILVISHDNLGLINDCLLNDFLLKSHQLDYKIAINLRENN
EEEEEEECCCHHHHEEEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCC
AAFHSVSLPYIELFNERSNNPIVIFQQSLKELMSFALK
CEEEEECCHHHHHHCCCCCCCEEEEHHHHHHHHHHHCC
>Mature Secondary Structure
MLFISATNTNAGKTTCARLLAQYCNACGVRTILLKPIETGVNDTTNHFSDVHLFLQDNRL
CEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEEEEHHHCCCCCCCCCCCEEEEEEECCEE
LDRSLTLKDISFYRYAKASAPLIAQQEENQNAPIDTNDLIQRLQNFTKTYDLVIVEGAGG
ECCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCEEEEEEEECCCC
LCVPITLEENMLDLALKLKAKILVISHDNLGLINDCLLNDFLLKSHQLDYKIAINLRENN
EEEEEEECCCHHHHEEEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCC
AAFHSVSLPYIELFNERSNNPIVIFQQSLKELMSFALK
CEEEEECCHHHHHHCCCCCCCEEEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]