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The map label for this gene is pldB [H]

Identifier: 187935647

GI number: 187935647

Start: 2384609

End: 2385691

Strand: Reverse

Name: pldB [H]

Synonym: CLL_A2313

Alternate gene names: 187935647

Gene position: 2385691-2384609 (Counterclockwise)

Preceding gene: 187932498

Following gene: 187935366

Centisome position: 62.78

GC content: 28.35

Gene sequence:

>1083_bases
ATGTGCAAAAATATTAAAAAAACGATTGCTATTTTTACTATGATGGTTTTAATGACTCTATGTTTTGAATTACCATATCA
ACAAGTTTTTGCTTTTGATAAAACTTCACTAGAAGGTATTTATGTATCAGAAGAAAACTATGAAGAAAAAATGAAGGATA
TAGTAGAGCCTTATATTGATAACATAAAAGAGACAGGCTTTGTACAGGGACAAGAAGGCATTGACATATATTATGAGATG
TATAAATTAAATGACTCAAAGGGAAATATAGTAATAAGTCATGGATTTTCAGAATCATTAGAAAAATATAATGAAATAAT
TTATTATTTCTTAAATCAAGGATATTCAGTTTTTGGATTAGAACATAGAGGACATGGTAGATCAGGTTCTCTTGGAGTAA
AAGATAAAAGTCAAATAAATGTAAAAGACTTTGAACATTATGTTTTAGATTTAAAAGAATTAATGGATAAAGTTGTTATG
CCTAATTCTGATGGAGAAAAAGTATTTTTATTTGCACATTCTATGGGTGGCGGTATCGGTAGTAAGTTTTTAGAAGAATA
CCCAGAATATTTTGACGCAGCAGTTTTAACTTCACCTATGTTAGAAATAAATACAGGTAAAGTACCATCAAGTATAGTTA
AATTAATAGCTAATACAAGTGTAGCTTTATCATTTGGCGATAAATATATAGCTGGACAAGGTAAATATGATGATACTTAT
GATTTAAAAGGTTCGGATACATCATCAGATGCTAGATGTAGATATTATCATAATATAGTAAGTGGAAATGAGGAATTACA
AAGAGGTGGAGCTTCATATAATTGGCTTCAAACATCAATATATGCGACTAAAGAAATTACAAATAAAGAAAATGCAGCAA
AAGTCGAGATTCCTGTAATATTAATGCAAGCTGATAAAGATGATTTTGTAAGGCCAGGTGGACAAAACAATTTCACTAAG
TATGCCCAAGATTGTGATAAAGTATTTTATGAAGAATCTAAGCACGGGATTTTTAGAGAGAATGATAAAATATTGCATGA
ATATTTAAATAATTTATTTGCATTTTATGAAGCAAACTTATAA

Upstream 100 bases:

>100_bases
TATTTTGATATTGTTAAATATAGAAATTCAGTTTACAATTAAAGTAATCGATTACATAATTAGTTATAACTAAAAATAAT
TAGTGAAAAGGGGACTTTTA

Downstream 100 bases:

>100_bases
TAATAAAAGTTATAATAAGCAATAAAAAAAGATATCTTGGAAAATCCAAGATATCTTTTTTAGTAAAAATTATTATTTAT
TTTTTTAAGTTTTCTTTTTT

Product: lysophospholipase l2 pldb, hydrolase of alpha/beta superfamily

Products: NA

Alternate protein names: Lecithinase B [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MCKNIKKTIAIFTMMVLMTLCFELPYQQVFAFDKTSLEGIYVSEENYEEKMKDIVEPYIDNIKETGFVQGQEGIDIYYEM
YKLNDSKGNIVISHGFSESLEKYNEIIYYFLNQGYSVFGLEHRGHGRSGSLGVKDKSQINVKDFEHYVLDLKELMDKVVM
PNSDGEKVFLFAHSMGGGIGSKFLEEYPEYFDAAVLTSPMLEINTGKVPSSIVKLIANTSVALSFGDKYIAGQGKYDDTY
DLKGSDTSSDARCRYYHNIVSGNEELQRGGASYNWLQTSIYATKEITNKENAAKVEIPVILMQADKDDFVRPGGQNNFTK
YAQDCDKVFYEESKHGIFRENDKILHEYLNNLFAFYEANL

Sequences:

>Translated_360_residues
MCKNIKKTIAIFTMMVLMTLCFELPYQQVFAFDKTSLEGIYVSEENYEEKMKDIVEPYIDNIKETGFVQGQEGIDIYYEM
YKLNDSKGNIVISHGFSESLEKYNEIIYYFLNQGYSVFGLEHRGHGRSGSLGVKDKSQINVKDFEHYVLDLKELMDKVVM
PNSDGEKVFLFAHSMGGGIGSKFLEEYPEYFDAAVLTSPMLEINTGKVPSSIVKLIANTSVALSFGDKYIAGQGKYDDTY
DLKGSDTSSDARCRYYHNIVSGNEELQRGGASYNWLQTSIYATKEITNKENAAKVEIPVILMQADKDDFVRPGGQNNFTK
YAQDCDKVFYEESKHGIFRENDKILHEYLNNLFAFYEANL
>Mature_360_residues
MCKNIKKTIAIFTMMVLMTLCFELPYQQVFAFDKTSLEGIYVSEENYEEKMKDIVEPYIDNIKETGFVQGQEGIDIYYEM
YKLNDSKGNIVISHGFSESLEKYNEIIYYFLNQGYSVFGLEHRGHGRSGSLGVKDKSQINVKDFEHYVLDLKELMDKVVM
PNSDGEKVFLFAHSMGGGIGSKFLEEYPEYFDAAVLTSPMLEINTGKVPSSIVKLIANTSVALSFGDKYIAGQGKYDDTY
DLKGSDTSSDARCRYYHNIVSGNEELQRGGASYNWLQTSIYATKEITNKENAAKVEIPVILMQADKDDFVRPGGQNNFTK
YAQDCDKVFYEESKHGIFRENDKILHEYLNNLFAFYEANL

Specific function: Unknown

COG id: COG2267

COG function: function code I; Lysophospholipase

Gene ontology:

Cell location: Cell inner membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI51242953, Length=278, Percent_Identity=25.5395683453237, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI6005786, Length=278, Percent_Identity=25.5395683453237, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI48994980, Length=242, Percent_Identity=30.9917355371901, Blast_Score=112, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.5 [H]

Molecular weight: Translated: 41057; Mature: 41057

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCKNIKKTIAIFTMMVLMTLCFELPYQQVFAFDKTSLEGIYVSEENYEEKMKDIVEPYID
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHH
NIKETGFVQGQEGIDIYYEMYKLNDSKGNIVISHGFSESLEKYNEIIYYFLNQGYSVFGL
HHHHCCCCCCCCCCEEEEEEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHCCCEEEEE
EHRGHGRSGSLGVKDKSQINVKDFEHYVLDLKELMDKVVMPNSDGEKVFLFAHSMGGGIG
EECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHH
SKFLEEYPEYFDAAVLTSPMLEINTGKVPSSIVKLIANTSVALSFGDKYIAGQGKYDDTY
HHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHCCCEEEECCCEEEECCCCCCCCC
DLKGSDTSSDARCRYYHNIVSGNEELQRGGASYNWLQTSIYATKEITNKENAAKVEIPVI
CCCCCCCCCCCHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEE
LMQADKDDFVRPGGQNNFTKYAQDCDKVFYEESKHGIFRENDKILHEYLNNLFAFYEANL
EEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MCKNIKKTIAIFTMMVLMTLCFELPYQQVFAFDKTSLEGIYVSEENYEEKMKDIVEPYID
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHH
NIKETGFVQGQEGIDIYYEMYKLNDSKGNIVISHGFSESLEKYNEIIYYFLNQGYSVFGL
HHHHCCCCCCCCCCEEEEEEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHCCCEEEEE
EHRGHGRSGSLGVKDKSQINVKDFEHYVLDLKELMDKVVMPNSDGEKVFLFAHSMGGGIG
EECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHH
SKFLEEYPEYFDAAVLTSPMLEINTGKVPSSIVKLIANTSVALSFGDKYIAGQGKYDDTY
HHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHCCCEEEECCCEEEECCCCCCCCC
DLKGSDTSSDARCRYYHNIVSGNEELQRGGASYNWLQTSIYATKEITNKENAAKVEIPVI
CCCCCCCCCCCHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEE
LMQADKDDFVRPGGQNNFTKYAQDCDKVFYEESKHGIFRENDKILHEYLNNLFAFYEANL
EEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]