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The map label for this gene is manA [H]

Identifier: 187935609

GI number: 187935609

Start: 3234700

End: 3235677

Strand: Reverse

Name: manA [H]

Synonym: CLL_A3124

Alternate gene names: 187935609

Gene position: 3235677-3234700 (Counterclockwise)

Preceding gene: 187933288

Following gene: 187932797

Centisome position: 85.14

GC content: 26.99

Gene sequence:

>978_bases
ATGTATCCAATTAAATTTAAAAATTTATACTATGATAGAATATGGGGCGGAAATGCTCTAAAAAAATTTAGAAGCAATAT
TCCAAATGGAGTGATAGGGGAAAGCTGGGATGTTGCATGTCATCCAAATGGAGTAGGCGAAGTAGAGAATGGAAGCTTAA
AAGGTAAAAAATTTGATGAAATAATTAATGAGTTTAAAGAAAAACTTATTGGCGAAAAAATAGATATAAAAAAATTTCCT
TTATTAATTAAATTAATTACATCTGGAGATAAACTATCAGTTCAAGTTCATCCAAATGATGAATATGCAAATAGAGTAGA
AAATGAGTTTGGTAAAACTGAAGCATGGTATGTTATTGATGCTGAAGAAAATGCAAGTTTAATAGTCGGTACAAAGGATT
GCGATAAAGAAATATTTAAAAAAGCTATTAAAGACGGAAATTTAGATAAATATTTAAATAAAATGCCTGTGAAAAAAGGT
GACTTTTTCTATGTACAAAGTGGATTAGTTCATGCTATATGTGAAGGTGTTTTAATAGCAGAAATTCAACAAAGCAGCGA
TATTACATATAGAGTTTATGACTATAATAGAGGCAGAGAAATACATGTAGAGAAAGCTTTAGATGTTATTGATTTTTCTT
TAGAAGGAAAGAACTCAAAAGGAATTTTAATAGAAAAAGAAAATTATAAAAAAACATACCTTTGTTTAAGTGATTATTTC
ACAATTCAAAAATATGAAATAAATAATTATGCAAAAGAAGAAAGTGATATAAATAGATTTTATTTATTCACGTGTGTAGA
TGGATGCGGAACTATAAAATATAAAAATGGCGAAGAAAAGATAGTAATGGGAGATAGTATATTCATACCTGCAACTATGG
GAGAATATGAATTAATAGGAAAATTCACATTATTAAAGAGCTATGTACCAGATGTAGAAAAAGAACAAAATGAAATTTTA
AGTGTAATAAAAAGATAA

Upstream 100 bases:

>100_bases
TAATTTAATTTTAACATAATGTAATTCACCTCATAAAAGTTTTACTATATAATATAACTATAATAATTAGAAATATTAAT
ATATTCATTAGGAGGGTAAT

Downstream 100 bases:

>100_bases
AGATAAGTCCAAGTTGGTGAATGTCACTAACTTGGACTTTTATTAAAAAATTTATATTCATATATCAACACTTTACTATG
ATTAAATTCCTTTAGGAGAA

Product: mannose-6-phosphate isomerase, class I

Products: NA

Alternate protein names: Phosphohexomutase; Phosphomannose isomerase; PMI [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MYPIKFKNLYYDRIWGGNALKKFRSNIPNGVIGESWDVACHPNGVGEVENGSLKGKKFDEIINEFKEKLIGEKIDIKKFP
LLIKLITSGDKLSVQVHPNDEYANRVENEFGKTEAWYVIDAEENASLIVGTKDCDKEIFKKAIKDGNLDKYLNKMPVKKG
DFFYVQSGLVHAICEGVLIAEIQQSSDITYRVYDYNRGREIHVEKALDVIDFSLEGKNSKGILIEKENYKKTYLCLSDYF
TIQKYEINNYAKEESDINRFYLFTCVDGCGTIKYKNGEEKIVMGDSIFIPATMGEYELIGKFTLLKSYVPDVEKEQNEIL
SVIKR

Sequences:

>Translated_325_residues
MYPIKFKNLYYDRIWGGNALKKFRSNIPNGVIGESWDVACHPNGVGEVENGSLKGKKFDEIINEFKEKLIGEKIDIKKFP
LLIKLITSGDKLSVQVHPNDEYANRVENEFGKTEAWYVIDAEENASLIVGTKDCDKEIFKKAIKDGNLDKYLNKMPVKKG
DFFYVQSGLVHAICEGVLIAEIQQSSDITYRVYDYNRGREIHVEKALDVIDFSLEGKNSKGILIEKENYKKTYLCLSDYF
TIQKYEINNYAKEESDINRFYLFTCVDGCGTIKYKNGEEKIVMGDSIFIPATMGEYELIGKFTLLKSYVPDVEKEQNEIL
SVIKR
>Mature_325_residues
MYPIKFKNLYYDRIWGGNALKKFRSNIPNGVIGESWDVACHPNGVGEVENGSLKGKKFDEIINEFKEKLIGEKIDIKKFP
LLIKLITSGDKLSVQVHPNDEYANRVENEFGKTEAWYVIDAEENASLIVGTKDCDKEIFKKAIKDGNLDKYLNKMPVKKG
DFFYVQSGLVHAICEGVLIAEIQQSSDITYRVYDYNRGREIHVEKALDVIDFSLEGKNSKGILIEKENYKKTYLCLSDYF
TIQKYEINNYAKEESDINRFYLFTCVDGCGTIKYKNGEEKIVMGDSIFIPATMGEYELIGKFTLLKSYVPDVEKEQNEIL
SVIKR

Specific function: Unknown

COG id: COG1482

COG function: function code G; Phosphomannose isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR001250
- InterPro:   IPR014628
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01238 PMI_typeI [H]

EC number: =5.3.1.8 [H]

Molecular weight: Translated: 37289; Mature: 37289

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPIKFKNLYYDRIWGGNALKKFRSNIPNGVIGESWDVACHPNGVGEVENGSLKGKKFDE
CCCEEECCEEEEEECCCHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHH
IINEFKEKLIGEKIDIKKFPLLIKLITSGDKLSVQVHPNDEYANRVENEFGKTEAWYVID
HHHHHHHHHCCCCCCCHHCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHCCCEEEEEEE
AEENASLIVGTKDCDKEIFKKAIKDGNLDKYLNKMPVKKGDFFYVQSGLVHAICEGVLIA
CCCCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEECCCHHHHHHCCHHEE
EIQQSSDITYRVYDYNRGREIHVEKALDVIDFSLEGKNSKGILIEKENYKKTYLCLSDYF
EECCCCCCEEEEEECCCCCEEEHHHHHEEEEEEECCCCCCCEEEECCCCCEEEEEEECCE
TIQKYEINNYAKEESDINRFYLFTCVDGCGTIKYKNGEEKIVMGDSIFIPATMGEYELIG
EEEEEECCCCCCCCCCCCEEEEEEEECCCCEEEEECCCCEEEECCCEEEEECCCCCHHHH
KFTLLKSYVPDVEKEQNEILSVIKR
HHHHHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MYPIKFKNLYYDRIWGGNALKKFRSNIPNGVIGESWDVACHPNGVGEVENGSLKGKKFDE
CCCEEECCEEEEEECCCHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHH
IINEFKEKLIGEKIDIKKFPLLIKLITSGDKLSVQVHPNDEYANRVENEFGKTEAWYVID
HHHHHHHHHCCCCCCCHHCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHCCCEEEEEEE
AEENASLIVGTKDCDKEIFKKAIKDGNLDKYLNKMPVKKGDFFYVQSGLVHAICEGVLIA
CCCCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEECCCHHHHHHCCHHEE
EIQQSSDITYRVYDYNRGREIHVEKALDVIDFSLEGKNSKGILIEKENYKKTYLCLSDYF
EECCCCCCEEEEEECCCCCEEEHHHHHEEEEEEECCCCCCCEEEECCCCCEEEEEEECCE
TIQKYEINNYAKEESDINRFYLFTCVDGCGTIKYKNGEEKIVMGDSIFIPATMGEYELIG
EEEEEECCCCCCCCCCCCEEEEEEEECCCCEEEEECCCCEEEECCCEEEEECCCCCHHHH
KFTLLKSYVPDVEKEQNEILSVIKR
HHHHHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8293960; 12397186 [H]