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The map label for this gene is iap [H]

Identifier: 187935561

GI number: 187935561

Start: 1994797

End: 1996254

Strand: Reverse

Name: iap [H]

Synonym: CLL_A1901

Alternate gene names: 187935561

Gene position: 1996254-1994797 (Counterclockwise)

Preceding gene: 187935081

Following gene: 187935272

Centisome position: 52.53

GC content: 30.66

Gene sequence:

>1458_bases
ATGGCTAAATCTCCTGAACTTGAACATATGAGTATTGGAAAAGCACAAACACTAGGAACTAAAAAAGTAAATGAATTATT
AGGATTAAAGAATTTAACAGATCAAACAACTGGAGAAGAAGCTAAGGCAATTAATAATACTTTAACAGCTCCTAGTGGTA
TTATTAAAAAATATGGACTTATACAGGATATTATTTTTAAATCTAAAAAAGAAGATCCAACTTTAAAAGCAAAAAGAATA
TTAAATGAGAACTGCAAGCCTAAGCAAACTATAGAAGTAGAATGTATTGGAGATATAGACTATAGAGTAGGTTTTGGAGT
TCATTTAGTTGCGCCATTTTTGCAAGGTTACGAAGATTGTTTTATGTATATTAAAGAAGTAGAACACGAATGGAAATCTA
ATAATTTATTTATAAGTAAGCTTACATTAACACCATCACGTGTTATGGATGAAATGGAATGGACAGATTTATATGATGAT
GAAGATGAAGAAGGAAGTTCAGCTTCAAGTTCTGCTTTATGGGAAAAAATTTATTCTGTTTTAAAACAACAAGAAGGCAA
ATCATATGTTTGGGGTGCACATGGACCAGATACATTTGACTGTAGTGGTCTAGTAGAATATTGTTACAACCAATACAAAG
CAGAATTAGGACTAACACTTGGTTGGACTACTTATGAGCAATGTAAACAAGGAACTGAGGTTGATAAAAATAGTAAAGAG
AGTTGGGAACCAGGAGATTTATTATTTTGGATTGGTAATGGTAGTTATCCAGCACCAGCTCATGTTAGTGTTTATATTGG
TGATAATAAAATGCTTCATGCCCCAAGAACTGGAGATGTAGTAAAAACTGTAGATGTTACAAGAACAGATATTTATTCTG
TTAAAAGAGTAATACCAGTAAGTAAGACTGGATATGCAGACATTAATATTGAAGGTGTTCCAGATGAATATGTGAGTAAT
TTAACTGCTGTTGAAGGTAATTGTAATACATTTATTTCTAATATGAGCAAATATAATTTTAAAGATATTATTATAAATAA
ATCTAATGTATATAAAATAGATGCTTATGTTACTGCTGCAATTATTGCAATAGAAAGTGAAGGAAATCCTTATTGTGGAG
GTTCGTATTACGGATTAATGCAAGTAAGTGGAGGTTCATCAGACCCAGCTAATAATATAGAGCAGGGATTAAAAGAATAT
AAGCAAAAAATGAGTGCTGTTGGCATTCAATCTCATGTAATTTTTTCAGCTTATAACAGTGGTGAAGGTACTGTTCTGAA
TTCCTGTAAGCAAAATGGATATAATACATCAACTGTAACAGTTAAGCAATTAGGAGATGCACTATATAGCTATGTTAAAT
CTCATAATCCTACTTGGGATGCTAATGAAAAGAAATATTATGCTTCAAAAGTATTAAAAGCCTACAATATATTAAAAACT
AAAAATGCATTAAAGTAA

Upstream 100 bases:

>100_bases
TGATTACAAGAGTTCAATTATTCGATAGTAAAGGTAATGCTGTAGATATAGAAACTGGAGAATCTGCTGAAGGTGATGAG
GATGAAGGTGGTGAAGAATA

Downstream 100 bases:

>100_bases
AAAGAGGTGATATGATGTCTTCATCATTTGATGAATTTTGGAACTCTATAGATTTACAACAAAAAAATAACACAATTGAT
GAACCTTTTGAAATAGGAAA

Product: NlpC/P60 family protein

Products: NA

Alternate protein names: Invasion-associated protein [H]

Number of amino acids: Translated: 485; Mature: 484

Protein sequence:

>485_residues
MAKSPELEHMSIGKAQTLGTKKVNELLGLKNLTDQTTGEEAKAINNTLTAPSGIIKKYGLIQDIIFKSKKEDPTLKAKRI
LNENCKPKQTIEVECIGDIDYRVGFGVHLVAPFLQGYEDCFMYIKEVEHEWKSNNLFISKLTLTPSRVMDEMEWTDLYDD
EDEEGSSASSSALWEKIYSVLKQQEGKSYVWGAHGPDTFDCSGLVEYCYNQYKAELGLTLGWTTYEQCKQGTEVDKNSKE
SWEPGDLLFWIGNGSYPAPAHVSVYIGDNKMLHAPRTGDVVKTVDVTRTDIYSVKRVIPVSKTGYADINIEGVPDEYVSN
LTAVEGNCNTFISNMSKYNFKDIIINKSNVYKIDAYVTAAIIAIESEGNPYCGGSYYGLMQVSGGSSDPANNIEQGLKEY
KQKMSAVGIQSHVIFSAYNSGEGTVLNSCKQNGYNTSTVTVKQLGDALYSYVKSHNPTWDANEKKYYASKVLKAYNILKT
KNALK

Sequences:

>Translated_485_residues
MAKSPELEHMSIGKAQTLGTKKVNELLGLKNLTDQTTGEEAKAINNTLTAPSGIIKKYGLIQDIIFKSKKEDPTLKAKRI
LNENCKPKQTIEVECIGDIDYRVGFGVHLVAPFLQGYEDCFMYIKEVEHEWKSNNLFISKLTLTPSRVMDEMEWTDLYDD
EDEEGSSASSSALWEKIYSVLKQQEGKSYVWGAHGPDTFDCSGLVEYCYNQYKAELGLTLGWTTYEQCKQGTEVDKNSKE
SWEPGDLLFWIGNGSYPAPAHVSVYIGDNKMLHAPRTGDVVKTVDVTRTDIYSVKRVIPVSKTGYADINIEGVPDEYVSN
LTAVEGNCNTFISNMSKYNFKDIIINKSNVYKIDAYVTAAIIAIESEGNPYCGGSYYGLMQVSGGSSDPANNIEQGLKEY
KQKMSAVGIQSHVIFSAYNSGEGTVLNSCKQNGYNTSTVTVKQLGDALYSYVKSHNPTWDANEKKYYASKVLKAYNILKT
KNALK
>Mature_484_residues
AKSPELEHMSIGKAQTLGTKKVNELLGLKNLTDQTTGEEAKAINNTLTAPSGIIKKYGLIQDIIFKSKKEDPTLKAKRIL
NENCKPKQTIEVECIGDIDYRVGFGVHLVAPFLQGYEDCFMYIKEVEHEWKSNNLFISKLTLTPSRVMDEMEWTDLYDDE
DEEGSSASSSALWEKIYSVLKQQEGKSYVWGAHGPDTFDCSGLVEYCYNQYKAELGLTLGWTTYEQCKQGTEVDKNSKES
WEPGDLLFWIGNGSYPAPAHVSVYIGDNKMLHAPRTGDVVKTVDVTRTDIYSVKRVIPVSKTGYADINIEGVPDEYVSNL
TAVEGNCNTFISNMSKYNFKDIIINKSNVYKIDAYVTAAIIAIESEGNPYCGGSYYGLMQVSGGSSDPANNIEQGLKEYK
QKMSAVGIQSHVIFSAYNSGEGTVLNSCKQNGYNTSTVTVKQLGDALYSYVKSHNPTWDANEKKYYASKVLKAYNILKTK
NALK

Specific function: This major extracellular protein may be involved in the invasion of non-professional phagocytic cells by Listeria [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1786421, Length=103, Percent_Identity=39.8058252427184, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482
- InterPro:   IPR003646
- InterPro:   IPR013247 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60; PF08239 SH3_3 [H]

EC number: NA

Molecular weight: Translated: 53995; Mature: 53864

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSPELEHMSIGKAQTLGTKKVNELLGLKNLTDQTTGEEAKAINNTLTAPSGIIKKYGL
CCCCCCCCHHCCCCHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHH
IQDIIFKSKKEDPTLKAKRILNENCKPKQTIEVECIGDIDYRVGFGVHLVAPFLQGYEDC
HHHHHHHCCCCCCCHHHHHHHCCCCCCCCEEEEEEEECCCEECCCHHHHHHHHHHCHHHH
FMYIKEVEHEWKSNNLFISKLTLTPSRVMDEMEWTDLYDDEDEEGSSASSSALWEKIYSV
HHHHHHHHHHHCCCCEEEEEEECCHHHHHHHCHHHCCCCCCCCCCCCCHHHHHHHHHHHH
LKQQEGKSYVWGAHGPDTFDCSGLVEYCYNQYKAELGLTLGWTTYEQCKQGTEVDKNSKE
HHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCEECCCCHHHHHCCCCCCCCCCC
SWEPGDLLFWIGNGSYPAPAHVSVYIGDNKMLHAPRTGDVVKTVDVTRTDIYSVKRVIPV
CCCCCCEEEEECCCCCCCCCEEEEEECCCEEEECCCCCCEEEEEECCHHHHHHHHHHCCC
SKTGYADINIEGVPDEYVSNLTAVEGNCNTFISNMSKYNFKDIIINKSNVYKIDAYVTAA
CCCCCEEEEECCCCHHHHCCCEEECCCHHHHHHHHCCCCCEEEEEECCCEEEEEEEEEEE
IIAIESEGNPYCGGSYYGLMQVSGGSSDPANNIEQGLKEYKQKMSAVGIQSHVIFSAYNS
EEEEECCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
GEGTVLNSCKQNGYNTSTVTVKQLGDALYSYVKSHNPTWDANEKKYYASKVLKAYNILKT
CCCHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
KNALK
HCCCC
>Mature Secondary Structure 
AKSPELEHMSIGKAQTLGTKKVNELLGLKNLTDQTTGEEAKAINNTLTAPSGIIKKYGL
CCCCCCCHHCCCCHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHH
IQDIIFKSKKEDPTLKAKRILNENCKPKQTIEVECIGDIDYRVGFGVHLVAPFLQGYEDC
HHHHHHHCCCCCCCHHHHHHHCCCCCCCCEEEEEEEECCCEECCCHHHHHHHHHHCHHHH
FMYIKEVEHEWKSNNLFISKLTLTPSRVMDEMEWTDLYDDEDEEGSSASSSALWEKIYSV
HHHHHHHHHHHCCCCEEEEEEECCHHHHHHHCHHHCCCCCCCCCCCCCHHHHHHHHHHHH
LKQQEGKSYVWGAHGPDTFDCSGLVEYCYNQYKAELGLTLGWTTYEQCKQGTEVDKNSKE
HHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCEECCCCHHHHHCCCCCCCCCCC
SWEPGDLLFWIGNGSYPAPAHVSVYIGDNKMLHAPRTGDVVKTVDVTRTDIYSVKRVIPV
CCCCCCEEEEECCCCCCCCCEEEEEECCCEEEECCCCCCEEEEEECCHHHHHHHHHHCCC
SKTGYADINIEGVPDEYVSNLTAVEGNCNTFISNMSKYNFKDIIINKSNVYKIDAYVTAA
CCCCCEEEEECCCCHHHHCCCEEECCCHHHHHHHHCCCCCEEEEEECCCEEEEEEEEEEE
IIAIESEGNPYCGGSYYGLMQVSGGSSDPANNIEQGLKEYKQKMSAVGIQSHVIFSAYNS
EEEEECCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
GEGTVLNSCKQNGYNTSTVTVKQLGDALYSYVKSHNPTWDANEKKYYASKVLKAYNILKT
CCCHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
KNALK
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1514809; 1459966 [H]