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The map label for this gene is tig [H]

Identifier: 187934599

GI number: 187934599

Start: 2970278

End: 2971561

Strand: Reverse

Name: tig [H]

Synonym: CLL_A2890

Alternate gene names: 187934599

Gene position: 2971561-2970278 (Counterclockwise)

Preceding gene: 187933957

Following gene: 187935559

Centisome position: 78.19

GC content: 28.89

Gene sequence:

>1284_bases
ATGGAAGCTAAAGTTGAAAAGATAGAAACAAATGTGGTTAAATTAGAAATAAAAGTTGAAGCAGAAAAATTTGATGCCGC
ATTAACTAAAGCATATAATAAAAATAAAGGTAAATATAATGTGCCAGGATTCAGAAAAGGCAAAGTTCCAATGGCAATAC
TAAAGAAAATGTATGGCATTGAAATTTTTTATGATGATGCTGTTAATATAGCTATAGATGAAAGTTATAATGAAGCATTA
AAGGCTGAAGATATCAGACCAGTTGATTATCCAAAGGTTGATATTGTTGAAATAGGAGAAGGTAAGGAACTTGTTTATAC
AGCAACAGTTACTACATACCCTGAAGTAGAAATCGGAGAATATAAAGGTTTAGATATTAAAAAACCTTCATATGAAGTAT
CTGAAGAAGAAGTTGAAAAACAAGTAAAAGAAATGCAATCTAAAAATGCAAGAATTGAAACTAAAGAAGAAGGAACAATA
GCAGATGGAAACATAGCTATAATCGACTTCAAAGGATTTGTAGATGGTGAAGCATTTGAAGGTGGAGAAGGTACTGATTA
TCCATTAGAAATAGGATCAGGTACATTTATTGATAACTTTGAAGAACAATTAATAGGTTTAGCTATAGGAGATAAAAAGG
AAGTTAATGTTACTTTCCCAGAAAACTATGGTAAAGAAGAATTAAATGCTAAGCCAGCAATGTTTGAAGTAACAGTAAAA
GGAATCAAAGCTAAAGAATTACCAGAATTAGATGATGAATTTGCTAAGGAAGTATCTGAATTTGATACATTAGCAGAATT
AAAAGAAAATATAAAGAAAAGATTAGAAGAATCTAATGATGAAAGAGCTGAAAGAGAATTTGAAGAAGCTGTTATAACTT
CAATAATTGAAACTTCAAAAATAGATCTTCCAGAAGTAATGTTAACTAAAGAAATAGATTCTATGATGAAAGATCTTGAA
TCAAGATTACAATATCAAGGATTAAGCTTAGATCAATACATGGAATTCACAGGAAACACAATGGAAAAAATGAGAGAATT
CATGAAAGAAAATGCTGAAAGAAAAGTTAAAGCTGACATAATTCTTGAATCAGTAGCTAAAGCTGAAGATGTAAAAGCAA
CTGATGAACAATTAAATGAAAGAGCATTAGAATTAGGTAGAATGTATGGACCTAAAGATCCTAAGAAGATGGCTAACATT
TTATTAAAAGCTCAAAAAGGTATGATTGAAAAAGATATAATTATAGAAAATACTCTTAAATTAATAAAAGAATCTTGTAA
ATAA

Upstream 100 bases:

>100_bases
AACAGTAATATTTATATAAATAATTTGATAAGAAACAGGGGTTTATGGTATAATAACCTAGTTAAATTAGATGTATACTA
TTTTAGGAGGAATTAATAAG

Downstream 100 bases:

>100_bases
TAGATATTATACAATTTTATAGTTTGAAAAATAATTGCCAGAAGTATTTCTGGCAATTATTTCAAATTATGATTAACATT
TTGGGTATTTTTTTATATAA

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MEAKVEKIETNVVKLEIKVEAEKFDAALTKAYNKNKGKYNVPGFRKGKVPMAILKKMYGIEIFYDDAVNIAIDESYNEAL
KAEDIRPVDYPKVDIVEIGEGKELVYTATVTTYPEVEIGEYKGLDIKKPSYEVSEEEVEKQVKEMQSKNARIETKEEGTI
ADGNIAIIDFKGFVDGEAFEGGEGTDYPLEIGSGTFIDNFEEQLIGLAIGDKKEVNVTFPENYGKEELNAKPAMFEVTVK
GIKAKELPELDDEFAKEVSEFDTLAELKENIKKRLEESNDERAEREFEEAVITSIIETSKIDLPEVMLTKEIDSMMKDLE
SRLQYQGLSLDQYMEFTGNTMEKMREFMKENAERKVKADIILESVAKAEDVKATDEQLNERALELGRMYGPKDPKKMANI
LLKAQKGMIEKDIIIENTLKLIKESCK

Sequences:

>Translated_427_residues
MEAKVEKIETNVVKLEIKVEAEKFDAALTKAYNKNKGKYNVPGFRKGKVPMAILKKMYGIEIFYDDAVNIAIDESYNEAL
KAEDIRPVDYPKVDIVEIGEGKELVYTATVTTYPEVEIGEYKGLDIKKPSYEVSEEEVEKQVKEMQSKNARIETKEEGTI
ADGNIAIIDFKGFVDGEAFEGGEGTDYPLEIGSGTFIDNFEEQLIGLAIGDKKEVNVTFPENYGKEELNAKPAMFEVTVK
GIKAKELPELDDEFAKEVSEFDTLAELKENIKKRLEESNDERAEREFEEAVITSIIETSKIDLPEVMLTKEIDSMMKDLE
SRLQYQGLSLDQYMEFTGNTMEKMREFMKENAERKVKADIILESVAKAEDVKATDEQLNERALELGRMYGPKDPKKMANI
LLKAQKGMIEKDIIIENTLKLIKESCK
>Mature_427_residues
MEAKVEKIETNVVKLEIKVEAEKFDAALTKAYNKNKGKYNVPGFRKGKVPMAILKKMYGIEIFYDDAVNIAIDESYNEAL
KAEDIRPVDYPKVDIVEIGEGKELVYTATVTTYPEVEIGEYKGLDIKKPSYEVSEEEVEKQVKEMQSKNARIETKEEGTI
ADGNIAIIDFKGFVDGEAFEGGEGTDYPLEIGSGTFIDNFEEQLIGLAIGDKKEVNVTFPENYGKEELNAKPAMFEVTVK
GIKAKELPELDDEFAKEVSEFDTLAELKENIKKRLEESNDERAEREFEEAVITSIIETSKIDLPEVMLTKEIDSMMKDLE
SRLQYQGLSLDQYMEFTGNTMEKMREFMKENAERKVKADIILESVAKAEDVKATDEQLNERALELGRMYGPKDPKKMANI
LLKAQKGMIEKDIIIENTLKLIKESCK

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation [H]

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786640, Length=401, Percent_Identity=28.6783042394015, Blast_Score=166, Evalue=3e-42,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881 [H]

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N [H]

EC number: NA

Molecular weight: Translated: 48430; Mature: 48430

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAKVEKIETNVVKLEIKVEAEKFDAALTKAYNKNKGKYNVPGFRKGKVPMAILKKMYGI
CCCHHHHHCCEEEEEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCC
EIFYDDAVNIAIDESYNEALKAEDIRPVDYPKVDIVEIGEGKELVYTATVTTYPEVEIGE
EEEEECCEEEEEECCHHHHHHCCCCCCCCCCCEEEEEECCCCEEEEEEEEEECCCEECCC
YKGLDIKKPSYEVSEEEVEKQVKEMQSKNARIETKEEGTIADGNIAIIDFKGFVDGEAFE
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCEECCCEEEEEECCCCCCCCCC
GGEGTDYPLEIGSGTFIDNFEEQLIGLAIGDKKEVNVTFPENYGKEELNAKPAMFEVTVK
CCCCCCCCEECCCCCCHHCHHHHHEEEEECCCCEEEEECCCCCCHHHCCCCCCEEEEEEC
GIKAKELPELDDEFAKEVSEFDTLAELKENIKKRLEESNDERAEREFEEAVITSIIETSK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
IDLPEVMLTKEIDSMMKDLESRLQYQGLSLDQYMEFTGNTMEKMREFMKENAERKVKADI
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
ILESVAKAEDVKATDEQLNERALELGRMYGPKDPKKMANILLKAQKGMIEKDIIIENTLK
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
LIKESCK
HHHHHCC
>Mature Secondary Structure
MEAKVEKIETNVVKLEIKVEAEKFDAALTKAYNKNKGKYNVPGFRKGKVPMAILKKMYGI
CCCHHHHHCCEEEEEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCC
EIFYDDAVNIAIDESYNEALKAEDIRPVDYPKVDIVEIGEGKELVYTATVTTYPEVEIGE
EEEEECCEEEEEECCHHHHHHCCCCCCCCCCCEEEEEECCCCEEEEEEEEEECCCEECCC
YKGLDIKKPSYEVSEEEVEKQVKEMQSKNARIETKEEGTIADGNIAIIDFKGFVDGEAFE
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCEECCCEEEEEECCCCCCCCCC
GGEGTDYPLEIGSGTFIDNFEEQLIGLAIGDKKEVNVTFPENYGKEELNAKPAMFEVTVK
CCCCCCCCEECCCCCCHHCHHHHHEEEEECCCCEEEEECCCCCCHHHCCCCCCEEEEEEC
GIKAKELPELDDEFAKEVSEFDTLAELKENIKKRLEESNDERAEREFEEAVITSIIETSK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
IDLPEVMLTKEIDSMMKDLESRLQYQGLSLDQYMEFTGNTMEKMREFMKENAERKVKADI
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
ILESVAKAEDVKATDEQLNERALELGRMYGPKDPKKMANILLKAQKGMIEKDIIIENTLK
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
LIKESCK
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA