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The map label for this gene is 187934435

Identifier: 187934435

GI number: 187934435

Start: 3123280

End: 3124161

Strand: Reverse

Name: 187934435

Synonym: CLL_A3022

Alternate gene names: NA

Gene position: 3124161-3123280 (Counterclockwise)

Preceding gene: 187933063

Following gene: 187934547

Centisome position: 82.21

GC content: 25.96

Gene sequence:

>882_bases
ATGAGTTTAAACAATTTAAGTAATAGAAGTAAAGGAATAATATTTATAATATTATCAGCATTTGGATTTGCAATGATGTC
AGCTTTTGTTAAGCTTTCAGGGGATTTACCATCTTTGCAAAAATCATTTTTTAGGAATTTAGTAGCAAGTTTAATTGCTT
TAAGTTTAATAATTAAGCATAAAGAAAGCTTTTTTGGAAAAAGAGAAAATCAAAAGATTCTTATATTAAGGTCTTTATTT
GGAACATTAGGAATTGTATTAAATTTTTATACAATAGATAAATTAGTGTTATCAGATGCTAATATGCTAAATAAGTTAAG
TCCATTTTTCGTAATTATTTTTTCAGCTTTATTTTTAAGTGAGAAAATAAATACAAAACAAATTGCATCTTTAATAATTG
CATTTTTAGGAGCCTTATTTATTATAAAACCATCATTTAATCTTGAAGTTATATCAGCTTTGGCAGGTGTTGGAGGTGCT
ATATTTGCAGCAGCAGCTTATACTTGTCTTAGAGTGCTTGGAGGAAAGGAAAAACATTATACAGTAGTATTTTATTTTTC
AACTTTTTCATCAATAGTATTGTTTCCATTTATGATGATGTCTTATAAGTCAATGACAATGATGCAACTAACTTATTTAA
TACTGGCAGGTGTTTTTGCAAGTGTAGGTCAATTTGGAGTAACTTTAGCTTATAAATATGCAGCAGCTAAAGAAATATCA
ATATTTGATTACTCAAACATACTATTCTCAGCTATAATAAGTTTAGTTATATTTGGAGCTTTACCAGATTACTTAAGTGT
TATAGGATATGTAATAATATTTGCAGCTTCATTATATATGTTTATGTACAATAAAAAATTAGATAAGGTTAAAATCAAAT
AA

Upstream 100 bases:

>100_bases
TAGTGGAAAGAATTTTATATAAATAATTTATTGAAACAAAATATTTAAAAATATATAAATTATATATAGATATTTATTTA
ACTAGGAAAGTGAGGAAATC

Downstream 100 bases:

>100_bases
ATACTACTTGAAAATAATTATAATGTTTGATATACTCAAGAAGAAAATTTAATAAAAAAATCCACTTTATTCAAAAAGTG
GGAGAGGTTCGAAGACCATC

Product: transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSLNNLSNRSKGIIFIILSAFGFAMMSAFVKLSGDLPSLQKSFFRNLVASLIALSLIIKHKESFFGKRENQKILILRSLF
GTLGIVLNFYTIDKLVLSDANMLNKLSPFFVIIFSALFLSEKINTKQIASLIIAFLGALFIIKPSFNLEVISALAGVGGA
IFAAAAYTCLRVLGGKEKHYTVVFYFSTFSSIVLFPFMMMSYKSMTMMQLTYLILAGVFASVGQFGVTLAYKYAAAKEIS
IFDYSNILFSAIISLVIFGALPDYLSVIGYVIIFAASLYMFMYNKKLDKVKIK

Sequences:

>Translated_293_residues
MSLNNLSNRSKGIIFIILSAFGFAMMSAFVKLSGDLPSLQKSFFRNLVASLIALSLIIKHKESFFGKRENQKILILRSLF
GTLGIVLNFYTIDKLVLSDANMLNKLSPFFVIIFSALFLSEKINTKQIASLIIAFLGALFIIKPSFNLEVISALAGVGGA
IFAAAAYTCLRVLGGKEKHYTVVFYFSTFSSIVLFPFMMMSYKSMTMMQLTYLILAGVFASVGQFGVTLAYKYAAAKEIS
IFDYSNILFSAIISLVIFGALPDYLSVIGYVIIFAASLYMFMYNKKLDKVKIK
>Mature_292_residues
SLNNLSNRSKGIIFIILSAFGFAMMSAFVKLSGDLPSLQKSFFRNLVASLIALSLIIKHKESFFGKRENQKILILRSLFG
TLGIVLNFYTIDKLVLSDANMLNKLSPFFVIIFSALFLSEKINTKQIASLIIAFLGALFIIKPSFNLEVISALAGVGGAI
FAAAAYTCLRVLGGKEKHYTVVFYFSTFSSIVLFPFMMMSYKSMTMMQLTYLILAGVFASVGQFGVTLAYKYAAAKEISI
FDYSNILFSAIISLVIFGALPDYLSVIGYVIIFAASLYMFMYNKKLDKVKIK

Specific function: Unknown

COG id: COG0697

COG function: function code GER; Permeases of the drug/metabolite transporter (DMT) superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DUF6 domains [H]

Homologues:

Organism=Homo sapiens, GI197927233, Length=283, Percent_Identity=24.3816254416961, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI23397492, Length=283, Percent_Identity=24.3816254416961, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323909, Length=242, Percent_Identity=25.2066115702479, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24645940, Length=286, Percent_Identity=27.2727272727273, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000620 [H]

Pfam domain/function: PF00892 DUF6 [H]

EC number: NA

Molecular weight: Translated: 32499; Mature: 32367

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNNLSNRSKGIIFIILSAFGFAMMSAFVKLSGDLPSLQKSFFRNLVASLIALSLIIKH
CCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KESFFGKRENQKILILRSLFGTLGIVLNFYTIDKLVLSDANMLNKLSPFFVIIFSALFLS
HHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKINTKQIASLIIAFLGALFIIKPSFNLEVISALAGVGGAIFAAAAYTCLRVLGGKEKHY
HCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCE
TVVFYFSTFSSIVLFPFMMMSYKSMTMMQLTYLILAGVFASVGQFGVTLAYKYAAAKEIS
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
IFDYSNILFSAIISLVIFGALPDYLSVIGYVIIFAASLYMFMYNKKLDKVKIK
EHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECC
>Mature Secondary Structure 
SLNNLSNRSKGIIFIILSAFGFAMMSAFVKLSGDLPSLQKSFFRNLVASLIALSLIIKH
CCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KESFFGKRENQKILILRSLFGTLGIVLNFYTIDKLVLSDANMLNKLSPFFVIIFSALFLS
HHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKINTKQIASLIIAFLGALFIIKPSFNLEVISALAGVGGAIFAAAAYTCLRVLGGKEKHY
HCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCE
TVVFYFSTFSSIVLFPFMMMSYKSMTMMQLTYLILAGVFASVGQFGVTLAYKYAAAKEIS
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
IFDYSNILFSAIISLVIFGALPDYLSVIGYVIIFAASLYMFMYNKKLDKVKIK
EHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]