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The map label for this gene is pgk [H]

Identifier: 187934425

GI number: 187934425

Start: 3169110

End: 3170300

Strand: Reverse

Name: pgk [H]

Synonym: CLL_A3065

Alternate gene names: 187934425

Gene position: 3170300-3169110 (Counterclockwise)

Preceding gene: 187934526

Following gene: 187933535

Centisome position: 83.42

GC content: 33.17

Gene sequence:

>1191_bases
ATGAATTTTAACAAAAAGACAATTGAAGATATCCAAGTAAAAGGAAAAAAAGTCTTAGTTAGATGTGATTTTAATGTACC
ATTAAAAGATGGTGTTATAACTGATGAAAATAGATTGAACGGAGCTCTTCCTACAATCAAATACTTAGTTGAAAATGGTG
CAAAAGTTATCCTTTGCTCACATATGGGTAAACCAAAGGGAGAACCAAAGCCAGAATTATCTTTAGCTCCAGTTGCTAAA
AGATTAAGTGAACTTTTAGGAAAAGAAATTAAATTTGCTCCAGACAACACTGTTGTAGGCGAAAATGCTAAAGCAGCAGT
TGCTGAAATGAAAGATGGAGATGTAGTATTACTTGAAAATACTAGATATAGAAAAGAAGAAACTAAGAATGGTGAAGAAT
TCTCTAAGGAATTAGCATCACTTGCTGAAATTTTTGTTAATGATGCATTTGGTACTGCTCACAGAGCTCACTGTTCAACA
GTTGGTGTAACTGATTATATTGACACTGCTGTATGTGGATACTTAATTCAAAAAGAATTAAAGTTCTTAGGAAATGCAGT
TGAAACTCCAGAAAAACCTTTTGTTGCTATATTAGGTGGAGCTAAGGTTTCTGATAAAATAGCTGTTATCAACAATCTTT
TAGATAAAGTTGATACTATTATAATTGGTGGAGGAATGGCTTATACATTCTTAAAAGCTCAAGGATATGAAATTGGAACT
TCATTAGTTGAAGAAGATAGACTTGACTATGCTAAAGAAATGATAGCTAAAGCAGAAGAAAAAAGTGTTAAATTCTTATT
ACCAGTAGATCATAGAGTTGCTGCAGAATTCAAAGATGTTGAAGCTACAGTAACAAATGATCAAAATATTCCAACTGGAA
ACATGGGATTAGATATTGGACCAAAGACAGAAACAGTATATGCTAATGCTATTAAAGATGCTAAGACTGTAATTTGGAAT
GGACCAATGGGAGTATTCGAATTTGAAAACTTCAATAAAGGAACTATTGCAGTAGCTAAAGCAATGGCTGATTCAAATGC
AACTACTATAATTGGTGGTGGAGATTCAGCAGCCGCTGTTAACATATTAGGATTCGGAGATAAAATGACTCATATCTCAA
CTGGTGGTGGAGCATCACTAGAATTCTTAGAAGGTAAAGTATTACCTGGTATATCTGCATTAAACGACTAA

Upstream 100 bases:

>100_bases
AAGTAATTAAAATCATAAATAAGTCTGGTTTTGTAGTATAAGGCTATAAGGCCAGACTATTTTAAAATATAGAAAAATTT
AATATTTAGAGGTGAAAAAG

Downstream 100 bases:

>100_bases
TATTAAATAAGTTAGTAAAGGGTAAAACTTCTTAAAGGAGTTTTACCTTACTATGTAGAATTAGTTATTATAGAAATTTA
AAACTTTATGTTTTATTATA

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MNFNKKTIEDIQVKGKKVLVRCDFNVPLKDGVITDENRLNGALPTIKYLVENGAKVILCSHMGKPKGEPKPELSLAPVAK
RLSELLGKEIKFAPDNTVVGENAKAAVAEMKDGDVVLLENTRYRKEETKNGEEFSKELASLAEIFVNDAFGTAHRAHCST
VGVTDYIDTAVCGYLIQKELKFLGNAVETPEKPFVAILGGAKVSDKIAVINNLLDKVDTIIIGGGMAYTFLKAQGYEIGT
SLVEEDRLDYAKEMIAKAEEKSVKFLLPVDHRVAAEFKDVEATVTNDQNIPTGNMGLDIGPKTETVYANAIKDAKTVIWN
GPMGVFEFENFNKGTIAVAKAMADSNATTIIGGGDSAAAVNILGFGDKMTHISTGGGASLEFLEGKVLPGISALND

Sequences:

>Translated_396_residues
MNFNKKTIEDIQVKGKKVLVRCDFNVPLKDGVITDENRLNGALPTIKYLVENGAKVILCSHMGKPKGEPKPELSLAPVAK
RLSELLGKEIKFAPDNTVVGENAKAAVAEMKDGDVVLLENTRYRKEETKNGEEFSKELASLAEIFVNDAFGTAHRAHCST
VGVTDYIDTAVCGYLIQKELKFLGNAVETPEKPFVAILGGAKVSDKIAVINNLLDKVDTIIIGGGMAYTFLKAQGYEIGT
SLVEEDRLDYAKEMIAKAEEKSVKFLLPVDHRVAAEFKDVEATVTNDQNIPTGNMGLDIGPKTETVYANAIKDAKTVIWN
GPMGVFEFENFNKGTIAVAKAMADSNATTIIGGGDSAAAVNILGFGDKMTHISTGGGASLEFLEGKVLPGISALND
>Mature_396_residues
MNFNKKTIEDIQVKGKKVLVRCDFNVPLKDGVITDENRLNGALPTIKYLVENGAKVILCSHMGKPKGEPKPELSLAPVAK
RLSELLGKEIKFAPDNTVVGENAKAAVAEMKDGDVVLLENTRYRKEETKNGEEFSKELASLAEIFVNDAFGTAHRAHCST
VGVTDYIDTAVCGYLIQKELKFLGNAVETPEKPFVAILGGAKVSDKIAVINNLLDKVDTIIIGGGMAYTFLKAQGYEIGT
SLVEEDRLDYAKEMIAKAEEKSVKFLLPVDHRVAAEFKDVEATVTNDQNIPTGNMGLDIGPKTETVYANAIKDAKTVIWN
GPMGVFEFENFNKGTIAVAKAMADSNATTIIGGGDSAAAVNILGFGDKMTHISTGGGASLEFLEGKVLPGISALND

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505763, Length=418, Percent_Identity=48.0861244019139, Blast_Score=363, Evalue=1e-100,
Organism=Homo sapiens, GI31543397, Length=421, Percent_Identity=45.3681710213777, Blast_Score=344, Evalue=7e-95,
Organism=Escherichia coli, GI1789294, Length=391, Percent_Identity=43.7340153452685, Blast_Score=326, Evalue=1e-90,
Organism=Caenorhabditis elegans, GI17508823, Length=417, Percent_Identity=48.4412470023981, Blast_Score=373, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6319857, Length=414, Percent_Identity=47.3429951690821, Blast_Score=358, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24581203, Length=415, Percent_Identity=45.3012048192771, Blast_Score=341, Evalue=5e-94,
Organism=Drosophila melanogaster, GI17136394, Length=418, Percent_Identity=45.933014354067, Blast_Score=335, Evalue=3e-92,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824 [H]

Pfam domain/function: PF00162 PGK [H]

EC number: =2.7.2.3 [H]

Molecular weight: Translated: 42516; Mature: 42516

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFNKKTIEDIQVKGKKVLVRCDFNVPLKDGVITDENRLNGALPTIKYLVENGAKVILCS
CCCCHHHHHHHHCCCEEEEEEECCCCCCCCCEECCCCCCCCCHHHHHHHHHCCCEEEEEE
HMGKPKGEPKPELSLAPVAKRLSELLGKEIKFAPDNTVVGENAKAAVAEMKDGDVVLLEN
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCEECCCCHHHHHCCCCCCEEEEEC
TRYRKEETKNGEEFSKELASLAEIFVNDAFGTAHRAHCSTVGVTDYIDTAVCGYLIQKEL
CCCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHH
KFLGNAVETPEKPFVAILGGAKVSDKIAVINNLLDKVDTIIIGGGMAYTFLKAQGYEIGT
HHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCEEEECCCCEEEEEEECCCHHHH
SLVEEDRLDYAKEMIAKAEEKSVKFLLPVDHRVAAEFKDVEATVTNDQNIPTGNMGLDIG
HHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHCCEEEECCCCCCCCCCCCCCCC
PKTETVYANAIKDAKTVIWNGPMGVFEFENFNKGTIAVAKAMADSNATTIIGGGDSAAAV
CCCCEEEHHHHCCCCEEEECCCCCEEEECCCCCCCEEEEHHHCCCCCEEEEECCCCCEEE
NILGFGDKMTHISTGGGASLEFLEGKVLPGISALND
EEEECCCCEEEEECCCCCEEEEECCCCCCCCHHCCC
>Mature Secondary Structure
MNFNKKTIEDIQVKGKKVLVRCDFNVPLKDGVITDENRLNGALPTIKYLVENGAKVILCS
CCCCHHHHHHHHCCCEEEEEEECCCCCCCCCEECCCCCCCCCHHHHHHHHHCCCEEEEEE
HMGKPKGEPKPELSLAPVAKRLSELLGKEIKFAPDNTVVGENAKAAVAEMKDGDVVLLEN
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCEECCCCHHHHHCCCCCCEEEEEC
TRYRKEETKNGEEFSKELASLAEIFVNDAFGTAHRAHCSTVGVTDYIDTAVCGYLIQKEL
CCCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHH
KFLGNAVETPEKPFVAILGGAKVSDKIAVINNLLDKVDTIIIGGGMAYTFLKAQGYEIGT
HHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCEEEECCCCEEEEEEECCCHHHH
SLVEEDRLDYAKEMIAKAEEKSVKFLLPVDHRVAAEFKDVEATVTNDQNIPTGNMGLDIG
HHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHCCEEEECCCCCCCCCCCCCCCC
PKTETVYANAIKDAKTVIWNGPMGVFEFENFNKGTIAVAKAMADSNATTIIGGGDSAAAV
CCCCEEEHHHHCCCCEEEECCCCCEEEECCCCCCCEEEEHHHCCCCCEEEEECCCCCEEE
NILGFGDKMTHISTGGGASLEFLEGKVLPGISALND
EEEECCCCEEEEECCCCCEEEEECCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA