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The map label for this gene is mraY [H]

Identifier: 187934112

GI number: 187934112

Start: 2525425

End: 2526399

Strand: Reverse

Name: mraY [H]

Synonym: CLL_A2443

Alternate gene names: 187934112

Gene position: 2526399-2525425 (Counterclockwise)

Preceding gene: 187935120

Following gene: 187933915

Centisome position: 66.48

GC content: 29.44

Gene sequence:

>975_bases
ATGGGGGATACAATAAAAGAATTATTAAATCCAACAGTTTTATCAGCATTATTAATGGGATTTGCGTTTTCAATGGTTTT
AGGACCAATATTTATACCTATGCTGCATAAATTGAAATTTGGTCAAAACATAAGAACAGATGGACCTAAAAGTCATCTGA
AAAAATCAGGTACTCCAACTATGGGAGGACTTATATTCTTTATTTCAGTAAGTGTAACAATGCTTATTATTGAATATAAG
CCAACTGATGAAGGGATGATAGTATTATATTCATTAATTGCGTTTGGTATTATCGGATTTTTAGATGATATATTAAAAAT
AATTCATAGAGATAATTTAGGACTAAGAGCTTATCAAAAGATGATTTTATTATTACTATTTTCTATTGCGTTAGCTTATT
ATGGATATACTAATATAGGAACAGATATTATAATTCCATTTATGAATTCTAAATTGAATTTAGGAATTTTTTATATACCA
TTAGTAGTTGTGTATTATGCAGCAACAACTAATGCAGTAAATCTTACAGATGGAATAGATGGCCTTGCGTCATCAGTAAC
AGTTATAGTTTTAACTTTCTTTGCAATAGTAGGTTTTAAAACAGGACATTATCAAGTTGGCGTATTTTCAATTGCTCTTG
CAGGCGCGTTATTAGGATTTCTTCGATATAATGCTTTTCCAGCAAAAATATTTATGGGAGATACAGGATCATTAGCTCTT
GGAGGTGCAATAGCAACAATAGCTTTAATACTAAAAATGCCATTATTCATAATAATAGTTGGTGGAATATACGTAGTAGA
AACATTATCTGTTATCATACAAGTAACATCTTTTAAGACAACAGGTAAAAGAGTATTTAAAATGGCGCCTATCCATCATC
ATTTTGAACAATGCGGATGGAGTGAGGTTAAATTAGTTACAGTCTTTTCAATAATAACATTAATATTATGCATTATAGGC
TTTATTGCACTTTAA

Upstream 100 bases:

>100_bases
GTTAAAGCATCAAGATCAGCAAAATTTGAAGATATAGTAAAAAATATAGAAGCTTTATAGTACAACAAAGGAGGTGAACT
GCCTAAAAAGGCAGTATAAG

Downstream 100 bases:

>100_bases
TTAATTGAAAATAAATAATTGAAAGGTTATGTTTTAAATACATGTTGATATTTAGGATAATATCAACACTGCCTTAAAAC
AAAGCGTAATACGATAACAT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MGDTIKELLNPTVLSALLMGFAFSMVLGPIFIPMLHKLKFGQNIRTDGPKSHLKKSGTPTMGGLIFFISVSVTMLIIEYK
PTDEGMIVLYSLIAFGIIGFLDDILKIIHRDNLGLRAYQKMILLLLFSIALAYYGYTNIGTDIIIPFMNSKLNLGIFYIP
LVVVYYAATTNAVNLTDGIDGLASSVTVIVLTFFAIVGFKTGHYQVGVFSIALAGALLGFLRYNAFPAKIFMGDTGSLAL
GGAIATIALILKMPLFIIIVGGIYVVETLSVIIQVTSFKTTGKRVFKMAPIHHHFEQCGWSEVKLVTVFSIITLILCIIG
FIAL

Sequences:

>Translated_324_residues
MGDTIKELLNPTVLSALLMGFAFSMVLGPIFIPMLHKLKFGQNIRTDGPKSHLKKSGTPTMGGLIFFISVSVTMLIIEYK
PTDEGMIVLYSLIAFGIIGFLDDILKIIHRDNLGLRAYQKMILLLLFSIALAYYGYTNIGTDIIIPFMNSKLNLGIFYIP
LVVVYYAATTNAVNLTDGIDGLASSVTVIVLTFFAIVGFKTGHYQVGVFSIALAGALLGFLRYNAFPAKIFMGDTGSLAL
GGAIATIALILKMPLFIIIVGGIYVVETLSVIIQVTSFKTTGKRVFKMAPIHHHFEQCGWSEVKLVTVFSIITLILCIIG
FIAL
>Mature_323_residues
GDTIKELLNPTVLSALLMGFAFSMVLGPIFIPMLHKLKFGQNIRTDGPKSHLKKSGTPTMGGLIFFISVSVTMLIIEYKP
TDEGMIVLYSLIAFGIIGFLDDILKIIHRDNLGLRAYQKMILLLLFSIALAYYGYTNIGTDIIIPFMNSKLNLGIFYIPL
VVVYYAATTNAVNLTDGIDGLASSVTVIVLTFFAIVGFKTGHYQVGVFSIALAGALLGFLRYNAFPAKIFMGDTGSLALG
GAIATIALILKMPLFIIIVGGIYVVETLSVIIQVTSFKTTGKRVFKMAPIHHHFEQCGWSEVKLVTVFSIITLILCIIGF
IAL

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=329, Percent_Identity=41.9452887537994, Blast_Score=244, Evalue=6e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 35306; Mature: 35175

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDTIKELLNPTVLSALLMGFAFSMVLGPIFIPMLHKLKFGQNIRTDGPKSHLKKSGTPT
CCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCC
MGGLIFFISVSVTMLIIEYKPTDEGMIVLYSLIAFGIIGFLDDILKIIHRDNLGLRAYQK
HHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
MILLLLFSIALAYYGYTNIGTDIIIPFMNSKLNLGIFYIPLVVVYYAATTNAVNLTDGID
HHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEECCCCHH
GLASSVTVIVLTFFAIVGFKTGHYQVGVFSIALAGALLGFLRYNAFPAKIFMGDTGSLAL
HHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHH
GGAIATIALILKMPLFIIIVGGIYVVETLSVIIQVTSFKTTGKRVFKMAPIHHHFEQCGW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHCCC
SEVKLVTVFSIITLILCIIGFIAL
CHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GDTIKELLNPTVLSALLMGFAFSMVLGPIFIPMLHKLKFGQNIRTDGPKSHLKKSGTPT
CCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCC
MGGLIFFISVSVTMLIIEYKPTDEGMIVLYSLIAFGIIGFLDDILKIIHRDNLGLRAYQK
HHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
MILLLLFSIALAYYGYTNIGTDIIIPFMNSKLNLGIFYIPLVVVYYAATTNAVNLTDGID
HHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEECCCCHH
GLASSVTVIVLTFFAIVGFKTGHYQVGVFSIALAGALLGFLRYNAFPAKIFMGDTGSLAL
HHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHH
GGAIATIALILKMPLFIIIVGGIYVVETLSVIIQVTSFKTTGKRVFKMAPIHHHFEQCGW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHCCC
SEVKLVTVFSIITLILCIIGFIAL
CHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA