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The map label for this gene is htpG [H]

Identifier: 187934082

GI number: 187934082

Start: 3078834

End: 3080765

Strand: Reverse

Name: htpG [H]

Synonym: CLL_A2988

Alternate gene names: 187934082

Gene position: 3080765-3078834 (Counterclockwise)

Preceding gene: 187933321

Following gene: 187935604

Centisome position: 81.07

GC content: 25.57

Gene sequence:

>1932_bases
ATGATAAAAGAAAATGGTAATATTTCAATTCATACAGAAAATATATTCCCTATTATTAAAAAATGGTTATATTCGGATAA
GGATATTTTCATTAGAGAACTTATAAGTAATGCTTGTGATGCTATAAGTAAATTAAAAAGATTATCAGCTTTAGGTGAAG
CAAATGTAGATGAAAATGAAAAATTTAAAGTTACAGTAATAGTAAATAAAGAGAAAAAAACTCTTAAATTTATTGATAAC
GGAATTGGAATGACAGAAGAAGAAGTTAAAAAATATATAAATCAAGTAGCTTTTTCAGGAGCAGAAGATTTTGTAGAGAA
GTACAAAGATAAAATGGATGAAGGTAGTGATATCATAGGTCATTTTGGACTAGGATTTTATTCAGCATTTATGGTTTCTG
ATAAAGTTCAAATTGATACATTATCATATAAAGAGGGCTTAGAACCTACAAGATGGATATGTGAAGGTGGTACTGAATTT
GAGATTTCTAACTCGGATTCTAAAAATGAAAGAGGTACAACAATAACTTTATATATCAATGAAGATAGTAATGAATTTTT
AGATGAATACAAGCTTAGAACTATTATTACTAAGTATTGTTCATTCTTACCTATAGAAATATATTTAGAAGATGAAAACA
AGGTAAAAGAAGAACCTAAATATGAAACAAAGAAAAATGAAGATGGAACTGAGTATCAAGAACTTATAACACCAGAAGAA
GCAAAACCTTTGAATGATACACATCCTCTTTGGATGAAAAAACCAAGCGAATGTACTGATGAAGAATATAAAGCTTTTTA
TAGACATGTATTTACTGATTTCAATGAACCGCTATTTTGGATTCATTTAAATGTGGATTATCCATTTAATTTAAAAGGAA
TATTATATTTCCCTAAATTAAAACATGAATTAGAAGCTACAGAAGGTCAAGTTAAGCTTTATAACAATCAAGTTTTTGTT
GCTGATAATATAAAAGAAGTAATTCCAGAATTTTTATTACTTTTAAAGGGTGCAATAGATTGTCCAGATTTACCTCTTAA
TGTTTCAAGAAGCTTTTTACAAAATGATAAAGATGTAGCTAAAATATCTAATCATATAATTAAAAAGGTTGCTGATAAGT
TAACTTCATTATTTAAAAATAGCAGAGACGAATATAATAAATTTTGGAATGATATACAAATATTCATTAAGTATGGTTGC
TTAAGAGATGAAAAATTCTATGAAAAAATTAAAGATATAATTATATTTAAGACTATTAATGATGAATATGTTACATTAAA
AGATTATTTAGAAAAAGCTAAAGAAAAACATGAAAATAAAGTATTCTATGTAAATGATGTAAGACAACAATCTCAATATA
TAAAATTATTTAAAGAATATGGATTAGATGCAATCATCTTAGATGCAAGTTTAGACAATCATCTAATATCTTTCTTAGAA
ATGAAAGAAAGTGGAGTACAATTTACTAGAATTGATTCAGATATATCAGATGTATTAAAATCTAATGAAGATTCTAATAA
TGAAGAAGTAAAAGAACTAAATAAGAAAATAGAGGAAACATTTAAATCTACTCTTGGTGAAAAGATAAAAAATATATCAG
TAGAAGGATTAAAGGATGCTGGAACTCCAGCTATGATATTAATATCTGAACAGTCAAGAAGAATGGCTGAAATGAGCAAA
ATGTATGCAGCTATGAATATGCCAGCGGGAATGTTTGATGAAGAAAAAACTTTAGTAGTAAATAGCAATAATACTATTGT
TAAAAAGATTATAAGTTTATATGAAGAAGATTCTAAAAAAGAAGATGTTAAATTCATTTGTGAACACATATTTGATTTAG
CTAAAATAGCTAATAAGGAATTAAGTCCAGAAGATATGGATGAATTTATAAAGAGAAATAATGAACTTTTAGAAAAAGTT
TTATCAATTTAG

Upstream 100 bases:

>100_bases
AGCATTGACAATATTTAGTTGTGTTAATAAAATATTCACTATAAAAAGAAATATAGTGTGAAGAAGCAAGTACACGAGAT
ATTAGAAGGAGTGATAGTTT

Downstream 100 bases:

>100_bases
TTTATAAATATATGTTAAGAACAGGTCTATATATGAATAAGCAAAGCTGGACAGAGTAATTATTATTAAAAAGGTACTTA
AAAAATTTTTTTAAGTACCT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 643; Mature: 643

Protein sequence:

>643_residues
MIKENGNISIHTENIFPIIKKWLYSDKDIFIRELISNACDAISKLKRLSALGEANVDENEKFKVTVIVNKEKKTLKFIDN
GIGMTEEEVKKYINQVAFSGAEDFVEKYKDKMDEGSDIIGHFGLGFYSAFMVSDKVQIDTLSYKEGLEPTRWICEGGTEF
EISNSDSKNERGTTITLYINEDSNEFLDEYKLRTIITKYCSFLPIEIYLEDENKVKEEPKYETKKNEDGTEYQELITPEE
AKPLNDTHPLWMKKPSECTDEEYKAFYRHVFTDFNEPLFWIHLNVDYPFNLKGILYFPKLKHELEATEGQVKLYNNQVFV
ADNIKEVIPEFLLLLKGAIDCPDLPLNVSRSFLQNDKDVAKISNHIIKKVADKLTSLFKNSRDEYNKFWNDIQIFIKYGC
LRDEKFYEKIKDIIIFKTINDEYVTLKDYLEKAKEKHENKVFYVNDVRQQSQYIKLFKEYGLDAIILDASLDNHLISFLE
MKESGVQFTRIDSDISDVLKSNEDSNNEEVKELNKKIEETFKSTLGEKIKNISVEGLKDAGTPAMILISEQSRRMAEMSK
MYAAMNMPAGMFDEEKTLVVNSNNTIVKKIISLYEEDSKKEDVKFICEHIFDLAKIANKELSPEDMDEFIKRNNELLEKV
LSI

Sequences:

>Translated_643_residues
MIKENGNISIHTENIFPIIKKWLYSDKDIFIRELISNACDAISKLKRLSALGEANVDENEKFKVTVIVNKEKKTLKFIDN
GIGMTEEEVKKYINQVAFSGAEDFVEKYKDKMDEGSDIIGHFGLGFYSAFMVSDKVQIDTLSYKEGLEPTRWICEGGTEF
EISNSDSKNERGTTITLYINEDSNEFLDEYKLRTIITKYCSFLPIEIYLEDENKVKEEPKYETKKNEDGTEYQELITPEE
AKPLNDTHPLWMKKPSECTDEEYKAFYRHVFTDFNEPLFWIHLNVDYPFNLKGILYFPKLKHELEATEGQVKLYNNQVFV
ADNIKEVIPEFLLLLKGAIDCPDLPLNVSRSFLQNDKDVAKISNHIIKKVADKLTSLFKNSRDEYNKFWNDIQIFIKYGC
LRDEKFYEKIKDIIIFKTINDEYVTLKDYLEKAKEKHENKVFYVNDVRQQSQYIKLFKEYGLDAIILDASLDNHLISFLE
MKESGVQFTRIDSDISDVLKSNEDSNNEEVKELNKKIEETFKSTLGEKIKNISVEGLKDAGTPAMILISEQSRRMAEMSK
MYAAMNMPAGMFDEEKTLVVNSNNTIVKKIISLYEEDSKKEDVKFICEHIFDLAKIANKELSPEDMDEFIKRNNELLEKV
LSI
>Mature_643_residues
MIKENGNISIHTENIFPIIKKWLYSDKDIFIRELISNACDAISKLKRLSALGEANVDENEKFKVTVIVNKEKKTLKFIDN
GIGMTEEEVKKYINQVAFSGAEDFVEKYKDKMDEGSDIIGHFGLGFYSAFMVSDKVQIDTLSYKEGLEPTRWICEGGTEF
EISNSDSKNERGTTITLYINEDSNEFLDEYKLRTIITKYCSFLPIEIYLEDENKVKEEPKYETKKNEDGTEYQELITPEE
AKPLNDTHPLWMKKPSECTDEEYKAFYRHVFTDFNEPLFWIHLNVDYPFNLKGILYFPKLKHELEATEGQVKLYNNQVFV
ADNIKEVIPEFLLLLKGAIDCPDLPLNVSRSFLQNDKDVAKISNHIIKKVADKLTSLFKNSRDEYNKFWNDIQIFIKYGC
LRDEKFYEKIKDIIIFKTINDEYVTLKDYLEKAKEKHENKVFYVNDVRQQSQYIKLFKEYGLDAIILDASLDNHLISFLE
MKESGVQFTRIDSDISDVLKSNEDSNNEEVKELNKKIEETFKSTLGEKIKNISVEGLKDAGTPAMILISEQSRRMAEMSK
MYAAMNMPAGMFDEEKTLVVNSNNTIVKKIISLYEEDSKKEDVKFICEHIFDLAKIANKELSPEDMDEFIKRNNELLEKV
LSI

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=669, Percent_Identity=25.4110612855007, Blast_Score=236, Evalue=5e-62,
Organism=Homo sapiens, GI20149594, Length=206, Percent_Identity=34.4660194174757, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI4507677, Length=193, Percent_Identity=37.8238341968912, Blast_Score=126, Evalue=7e-29,
Organism=Homo sapiens, GI154146191, Length=204, Percent_Identity=33.8235294117647, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI153792590, Length=204, Percent_Identity=33.8235294117647, Blast_Score=125, Evalue=1e-28,
Organism=Escherichia coli, GI1786679, Length=643, Percent_Identity=32.8149300155521, Blast_Score=294, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI17542208, Length=662, Percent_Identity=27.6435045317221, Blast_Score=238, Evalue=8e-63,
Organism=Caenorhabditis elegans, GI17559162, Length=640, Percent_Identity=26.875, Blast_Score=224, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI115535205, Length=667, Percent_Identity=25.9370314842579, Blast_Score=203, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI115535167, Length=441, Percent_Identity=28.5714285714286, Blast_Score=193, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6323840, Length=693, Percent_Identity=27.8499278499279, Blast_Score=225, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6325016, Length=695, Percent_Identity=26.9064748201439, Blast_Score=219, Evalue=1e-57,
Organism=Drosophila melanogaster, GI21357739, Length=676, Percent_Identity=28.1065088757396, Blast_Score=240, Evalue=2e-63,
Organism=Drosophila melanogaster, GI17647529, Length=656, Percent_Identity=27.4390243902439, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24586016, Length=450, Percent_Identity=30.4444444444444, Blast_Score=223, Evalue=3e-58,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 74804; Mature: 74804

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKENGNISIHTENIFPIIKKWLYSDKDIFIRELISNACDAISKLKRLSALGEANVDENE
CCCCCCCEEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
KFKVTVIVNKEKKTLKFIDNGIGMTEEEVKKYINQVAFSGAEDFVEKYKDKMDEGSDIIG
CEEEEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHH
HFGLGFYSAFMVSDKVQIDTLSYKEGLEPTRWICEGGTEFEISNSDSKNERGTTITLYIN
HHHHHHHHHHHHCCCEEEEEECHHHCCCHHHHHCCCCCEEEECCCCCCCCCCCEEEEEEE
EDSNEFLDEYKLRTIITKYCSFLPIEIYLEDENKVKEEPKYETKKNEDGTEYQELITPEE
CCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHCCCCCCCCCCCCCCCCHHHHHCCCCC
AKPLNDTHPLWMKKPSECTDEEYKAFYRHVFTDFNEPLFWIHLNVDYPFNLKGILYFPKL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCEEEECCHH
KHELEATEGQVKLYNNQVFVADNIKEVIPEFLLLLKGAIDCPDLPLNVSRSFLQNDKDVA
HHHHHCCCCEEEEECCEEEEECCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHH
KISNHIIKKVADKLTSLFKNSRDEYNKFWNDIQIFIKYGCLRDEKFYEKIKDIIIFKTIN
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEEEECC
DEYVTLKDYLEKAKEKHENKVFYVNDVRQQSQYIKLFKEYGLDAIILDASLDNHLISFLE
CCEEEHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHH
MKESGVQFTRIDSDISDVLKSNEDSNNEEVKELNKKIEETFKSTLGEKIKNISVEGLKDA
HHHCCCEEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GTPAMILISEQSRRMAEMSKMYAAMNMPAGMFDEEKTLVVNSNNTIVKKIISLYEEDSKK
CCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCH
EDVKFICEHIFDLAKIANKELSPEDMDEFIKRNNELLEKVLSI
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHCC
>Mature Secondary Structure
MIKENGNISIHTENIFPIIKKWLYSDKDIFIRELISNACDAISKLKRLSALGEANVDENE
CCCCCCCEEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
KFKVTVIVNKEKKTLKFIDNGIGMTEEEVKKYINQVAFSGAEDFVEKYKDKMDEGSDIIG
CEEEEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHH
HFGLGFYSAFMVSDKVQIDTLSYKEGLEPTRWICEGGTEFEISNSDSKNERGTTITLYIN
HHHHHHHHHHHHCCCEEEEEECHHHCCCHHHHHCCCCCEEEECCCCCCCCCCCEEEEEEE
EDSNEFLDEYKLRTIITKYCSFLPIEIYLEDENKVKEEPKYETKKNEDGTEYQELITPEE
CCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHCCCCCCCCCCCCCCCCHHHHHCCCCC
AKPLNDTHPLWMKKPSECTDEEYKAFYRHVFTDFNEPLFWIHLNVDYPFNLKGILYFPKL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCEEEECCHH
KHELEATEGQVKLYNNQVFVADNIKEVIPEFLLLLKGAIDCPDLPLNVSRSFLQNDKDVA
HHHHHCCCCEEEEECCEEEEECCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHH
KISNHIIKKVADKLTSLFKNSRDEYNKFWNDIQIFIKYGCLRDEKFYEKIKDIIIFKTIN
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEEEECC
DEYVTLKDYLEKAKEKHENKVFYVNDVRQQSQYIKLFKEYGLDAIILDASLDNHLISFLE
CCEEEHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHH
MKESGVQFTRIDSDISDVLKSNEDSNNEEVKELNKKIEETFKSTLGEKIKNISVEGLKDA
HHHCCCEEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GTPAMILISEQSRRMAEMSKMYAAMNMPAGMFDEEKTLVVNSNNTIVKKIISLYEEDSKK
CCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCH
EDVKFICEHIFDLAKIANKELSPEDMDEFIKRNNELLEKVLSI
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11807048 [H]