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The map label for this gene is ygbD [C]

Identifier: 187934039

GI number: 187934039

Start: 3130731

End: 3132065

Strand: Reverse

Name: ygbD [C]

Synonym: CLL_A3031

Alternate gene names: 187934039

Gene position: 3132065-3130731 (Counterclockwise)

Preceding gene: 187933064

Following gene: 187935565

Centisome position: 82.42

GC content: 30.41

Gene sequence:

>1335_bases
ATGAGAGTAGTAATTGTTGGTGGAATAGCAGCAGGTACAAGTGCAGCTGCAAAATTAAGAAGAGTAAACCCGGATGCTGA
AATCATAATTTATGAGAAATCAGATATAGTATCATTTGGTGCTTGTGGATTACCTTACTTCGTAGGAAATTTTTTTGAAG
ATTCACAAAATATGATTGCAAGAACTCCTGAAGAATTTATAAAAAGTGGAGTAGATGTTAAAACTAATCATGAGGTTGTT
AATATAGATTTTAATAATAAGTTGGTTACAGTAAAGAATCTGAAGACAGGTTCTCAATTTAATGATAAATATGATAAATT
AATGATAGCGACAGGTGCAAGGAGTATAATACCTCCAATTAAAAATGTTAATTTAAAAAATGTGTACACATTAAAAAGTA
TGGATGATGGAAAAATTTTAAAGCAGCTTTTGAGAGAAAAAAGCAATAAAAGTATAGCAATAGTAGGTGCAGGATTTATT
GGATTAGAGGCAGTAGAGGCAGCTAAAAGTCATGAAAAAGAGGTTTCAGTATTTCAATTGGAGGATCGAATATTAAAGGA
TGTTTTTGATAAAGAAATCACTGATGTATTAGAAAAAGAATTAAGAGACAAGGGAGTAAATTTATATTTACAAGAGACTG
TTACAGAACTTATAGGAGATGATAAAGTTACAAAAATATGTACAAATAAAAGAGAAATAAATGTGGATATAGTAATTATA
TCTACAGGTGTTAAGCCTAATACAGAGTTTATTAAAGATAGTGGAATAGATATGTTATCTAATGGAGCAATTATTGTAGA
TGAATATGGAAAAACATCAATTGAAGATGTTTATTCAGCTGGAGATTGTGCAACGATAAATCAAATTCTTACAAATGAAA
AAAGCTATGTTCCTCTTGCTACGGGCGCAAATAAACTTGGACGTATTGTTGGAGAAAATCTAGGAGGAGCTAATTTACCA
TTTCAAGGTTCATTATCATCTAGTTGTATAAAAGTTTTAGAGATTGAAGCTGGAAGAACAGGTATTACAGAAGAAAAAGC
TAAACAAATGGGATTGGGCTATAAGACTAAATTTATAACAGATATGAATCAAACTAGCTATTATCCAGGTCAAAGCAAAA
TTTACGTTAAATTAATATATGAAGCTAACAGTAAAAGAATATTAGGTGGTCAGGTTGCAGGATATAAAGATGCTGTACAG
AGAGTTAATGTTATTGCTGCATGCATATTTGGAAAATTAACAACTAAAGAACTTGGAATGCTGGATTTATGTTATTCACC
GCCATTTTCAAGAACTTGGGATGTATTAAATGTTGTAGGAAATATATGTAAGTAA

Upstream 100 bases:

>100_bases
CGATAAGAATATTGACCAATTAAAAGAAAGATATTATTATGTAGTAAAGAGTTAAGGTAAATAGGGAATATAATGTTTAA
TATAGATTAGGAGGAAAAAA

Downstream 100 bases:

>100_bases
ATACTGATGAATTAAAAAGGGATATTAGCTATACCAGAGCCAATATCCCTTTTTAAATTTAAGATGTTTTTAAATTTTAT
TAAGTTTTATTAAATGAAAA

Product: coenzyme A disulfide reductase

Products: NA

Alternate protein names: CoA-disulfide reductase; CoADR [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MRVVIVGGIAAGTSAAAKLRRVNPDAEIIIYEKSDIVSFGACGLPYFVGNFFEDSQNMIARTPEEFIKSGVDVKTNHEVV
NIDFNNKLVTVKNLKTGSQFNDKYDKLMIATGARSIIPPIKNVNLKNVYTLKSMDDGKILKQLLREKSNKSIAIVGAGFI
GLEAVEAAKSHEKEVSVFQLEDRILKDVFDKEITDVLEKELRDKGVNLYLQETVTELIGDDKVTKICTNKREINVDIVII
STGVKPNTEFIKDSGIDMLSNGAIIVDEYGKTSIEDVYSAGDCATINQILTNEKSYVPLATGANKLGRIVGENLGGANLP
FQGSLSSSCIKVLEIEAGRTGITEEKAKQMGLGYKTKFITDMNQTSYYPGQSKIYVKLIYEANSKRILGGQVAGYKDAVQ
RVNVIAACIFGKLTTKELGMLDLCYSPPFSRTWDVLNVVGNICK

Sequences:

>Translated_444_residues
MRVVIVGGIAAGTSAAAKLRRVNPDAEIIIYEKSDIVSFGACGLPYFVGNFFEDSQNMIARTPEEFIKSGVDVKTNHEVV
NIDFNNKLVTVKNLKTGSQFNDKYDKLMIATGARSIIPPIKNVNLKNVYTLKSMDDGKILKQLLREKSNKSIAIVGAGFI
GLEAVEAAKSHEKEVSVFQLEDRILKDVFDKEITDVLEKELRDKGVNLYLQETVTELIGDDKVTKICTNKREINVDIVII
STGVKPNTEFIKDSGIDMLSNGAIIVDEYGKTSIEDVYSAGDCATINQILTNEKSYVPLATGANKLGRIVGENLGGANLP
FQGSLSSSCIKVLEIEAGRTGITEEKAKQMGLGYKTKFITDMNQTSYYPGQSKIYVKLIYEANSKRILGGQVAGYKDAVQ
RVNVIAACIFGKLTTKELGMLDLCYSPPFSRTWDVLNVVGNICK
>Mature_444_residues
MRVVIVGGIAAGTSAAAKLRRVNPDAEIIIYEKSDIVSFGACGLPYFVGNFFEDSQNMIARTPEEFIKSGVDVKTNHEVV
NIDFNNKLVTVKNLKTGSQFNDKYDKLMIATGARSIIPPIKNVNLKNVYTLKSMDDGKILKQLLREKSNKSIAIVGAGFI
GLEAVEAAKSHEKEVSVFQLEDRILKDVFDKEITDVLEKELRDKGVNLYLQETVTELIGDDKVTKICTNKREINVDIVII
STGVKPNTEFIKDSGIDMLSNGAIIVDEYGKTSIEDVYSAGDCATINQILTNEKSYVPLATGANKLGRIVGENLGGANLP
FQGSLSSSCIKVLEIEAGRTGITEEKAKQMGLGYKTKFITDMNQTSYYPGQSKIYVKLIYEANSKRILGGQVAGYKDAVQ
RVNVIAACIFGKLTTKELGMLDLCYSPPFSRTWDVLNVVGNICK

Specific function: Unknown

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI226437568, Length=319, Percent_Identity=27.2727272727273, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI21389617, Length=319, Percent_Identity=27.2727272727273, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI65787454, Length=319, Percent_Identity=27.2727272727273, Blast_Score=120, Evalue=2e-27,
Organism=Escherichia coli, GI1789065, Length=270, Percent_Identity=29.6296296296296, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1789765, Length=380, Percent_Identity=23.9473684210526, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788892, Length=289, Percent_Identity=24.2214532871972, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786307, Length=300, Percent_Identity=23.3333333333333, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17559934, Length=231, Percent_Identity=30.3030303030303, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI281359715, Length=230, Percent_Identity=29.5652173913043, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI281359713, Length=230, Percent_Identity=29.5652173913043, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24639250, Length=230, Percent_Identity=29.5652173913043, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI18543267, Length=230, Percent_Identity=29.5652173913043, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24639252, Length=230, Percent_Identity=29.5652173913043, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24639257, Length=230, Percent_Identity=29.5652173913043, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24585130, Length=292, Percent_Identity=25.6849315068493, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28573993, Length=287, Percent_Identity=25.7839721254355, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24581020, Length=287, Percent_Identity=25.7839721254355, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21358499, Length=307, Percent_Identity=25.7328990228013, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017758
- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.14 [H]

Molecular weight: Translated: 48674; Mature: 48674

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVVIVGGIAAGTSAAAKLRRVNPDAEIIIYEKSDIVSFGACGLPYFVGNFFEDSQNMIA
CEEEEEECCCCCCHHHHHHHHCCCCCEEEEEECCCEEEECCCCHHHHHHHHHHCCCHHHH
RTPEEFIKSGVDVKTNHEVVNIDFNNKLVTVKNLKTGSQFNDKYDKLMIATGARSIIPPI
CCHHHHHHCCCCEECCCEEEEEECCCEEEEEEECCCCCCCCCCHHEEEEECCCCHHCCCC
KNVNLKNVYTLKSMDDGKILKQLLREKSNKSIAIVGAGFIGLEAVEAAKSHEKEVSVFQL
CCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCHHHHH
EDRILKDVFDKEITDVLEKELRDKGVNLYLQETVTELIGDDKVTKICTNKREINVDIVII
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCHHHHHHCCCEEEEEEEEEE
STGVKPNTEFIKDSGIDMLSNGAIIVDEYGKTSIEDVYSAGDCATINQILTNEKSYVPLA
ECCCCCCHHHHHCCCCCEECCCCEEEECCCCCCHHHHHCCCCHHHHHHHHCCCCCEEEEC
TGANKLGRIVGENLGGANLPFQGSLSSSCIKVLEIEAGRTGITEEKAKQMGLGYKTKFIT
CCCHHHHHHHCCCCCCCCCCCCCCCHHHHEEEEEEECCCCCCCHHHHHHHCCCCEEEEEE
DMNQTSYYPGQSKIYVKLIYEANSKRILGGQVAGYKDAVQRVNVIAACIFGKLTTKELGM
CCCCCCCCCCCCEEEEEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCE
LDLCYSPPFSRTWDVLNVVGNICK
EEEECCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRVVIVGGIAAGTSAAAKLRRVNPDAEIIIYEKSDIVSFGACGLPYFVGNFFEDSQNMIA
CEEEEEECCCCCCHHHHHHHHCCCCCEEEEEECCCEEEECCCCHHHHHHHHHHCCCHHHH
RTPEEFIKSGVDVKTNHEVVNIDFNNKLVTVKNLKTGSQFNDKYDKLMIATGARSIIPPI
CCHHHHHHCCCCEECCCEEEEEECCCEEEEEEECCCCCCCCCCHHEEEEECCCCHHCCCC
KNVNLKNVYTLKSMDDGKILKQLLREKSNKSIAIVGAGFIGLEAVEAAKSHEKEVSVFQL
CCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCHHHHH
EDRILKDVFDKEITDVLEKELRDKGVNLYLQETVTELIGDDKVTKICTNKREINVDIVII
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCHHHHHHCCCEEEEEEEEEE
STGVKPNTEFIKDSGIDMLSNGAIIVDEYGKTSIEDVYSAGDCATINQILTNEKSYVPLA
ECCCCCCHHHHHCCCCCEECCCCEEEECCCCCCHHHHHCCCCHHHHHHHHCCCCCEEEEC
TGANKLGRIVGENLGGANLPFQGSLSSSCIKVLEIEAGRTGITEEKAKQMGLGYKTKFIT
CCCHHHHHHHCCCCCCCCCCCCCCCHHHHEEEEEEECCCCCCCHHHHHHHCCCCEEEEEE
DMNQTSYYPGQSKIYVKLIYEANSKRILGGQVAGYKDAVQRVNVIAACIFGKLTTKELGM
CCCCCCCCCCCCEEEEEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCE
LDLCYSPPFSRTWDVLNVVGNICK
EEEECCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA