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The map label for this gene is ykuT [H]

Identifier: 187934005

GI number: 187934005

Start: 3785726

End: 3786619

Strand: Reverse

Name: ykuT [H]

Synonym: CLL_A3589

Alternate gene names: 187934005

Gene position: 3786619-3785726 (Counterclockwise)

Preceding gene: 187933029

Following gene: 187933207

Centisome position: 99.64

GC content: 26.96

Gene sequence:

>894_bases
ATGATTAATTATTTAATAAAATTTGATTGGAATCAAGAAGAGATAAAAATAGGTAAAATATTAATAAAGTTAAGTAATAT
TGAAACTTTAATAAATAAAACATTAATTATAATCGGTGTATTTATATTAATGTATATATCTATTAAAATAGGAAATTACT
TAATTAGAAAGTTTGTTGAAAGACAAGTAAAAAGCAATACAAGGTTATCTTTAGACTCACAACGTGCAAAAACACTTGGG
GAAGTAATGAAAAGTGTTTTAAAATATGCAGTTTATTTTATAGGTATAGCATCTATAATATCTACTTTATTTAAGGGATT
ATCATTTACATTTGCTAGTATGGGTGGATTAGCTGTTGGATTCGGTGCTCAAAGTTTGATTAAAGATTTAATAAATGGAT
TTTTCATATTATTCGAAGATCAATTTGGAGTTGGAGATCATATAACAGTAGGAACATTCAATGGAATAGTTGAAAGTATA
GGAATTAGAACTACAATAATAAAGGATTTTACTGGAGATATTCATTCTATCCCAAATGGTTCAATTATTCAGGTTACTAA
TCATTCAAGAGGCAATATAAGATTTATCGTGGATGTTGATATTGCATATGAAGAAAATATAGATAATGCAATTTCCATAA
TAAAAGAAGTTTGTTCAAACTTTGAACAAGATAATGAAGACATAAGAGAGCCTATAGAAGTATTAGGGGTGAATGCTTTA
AACGCTTCAAGTGTAACAATTAGAGTAATTGGAAAAAGCAAACCTCTTAAACAATGGGAAATGGAAAGAGAATTAAGAAA
GTTAATAAAATTGAGATTAGATAAAGAGGGAATAGAAATACCATATCCTAAGACTCAATTAGTAAGTGCTAACATGGAAA
AGGGGGATTTGTAA

Upstream 100 bases:

>100_bases
TAATTAAAGATAATAAATTTGAATATAAAAATATATACTTAAAAGATAATAATGGGTATGTTTCAATTGAATAAATTTAA
AATTAGGAGTGCTTCATTTA

Downstream 100 bases:

>100_bases
TGATAGAAACATTTGAACTTGGTGAAATAGTAAAAATGAAAAAACAACACCCATGTGGTTCATATGAGTTTGAAATTGTC
AGGTTAGGAGCAGATATAAA

Product: mechanosensitive ion channel family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MINYLIKFDWNQEEIKIGKILIKLSNIETLINKTLIIIGVFILMYISIKIGNYLIRKFVERQVKSNTRLSLDSQRAKTLG
EVMKSVLKYAVYFIGIASIISTLFKGLSFTFASMGGLAVGFGAQSLIKDLINGFFILFEDQFGVGDHITVGTFNGIVESI
GIRTTIIKDFTGDIHSIPNGSIIQVTNHSRGNIRFIVDVDIAYEENIDNAISIIKEVCSNFEQDNEDIREPIEVLGVNAL
NASSVTIRVIGKSKPLKQWEMERELRKLIKLRLDKEGIEIPYPKTQLVSANMEKGDL

Sequences:

>Translated_297_residues
MINYLIKFDWNQEEIKIGKILIKLSNIETLINKTLIIIGVFILMYISIKIGNYLIRKFVERQVKSNTRLSLDSQRAKTLG
EVMKSVLKYAVYFIGIASIISTLFKGLSFTFASMGGLAVGFGAQSLIKDLINGFFILFEDQFGVGDHITVGTFNGIVESI
GIRTTIIKDFTGDIHSIPNGSIIQVTNHSRGNIRFIVDVDIAYEENIDNAISIIKEVCSNFEQDNEDIREPIEVLGVNAL
NASSVTIRVIGKSKPLKQWEMERELRKLIKLRLDKEGIEIPYPKTQLVSANMEKGDL
>Mature_297_residues
MINYLIKFDWNQEEIKIGKILIKLSNIETLINKTLIIIGVFILMYISIKIGNYLIRKFVERQVKSNTRLSLDSQRAKTLG
EVMKSVLKYAVYFIGIASIISTLFKGLSFTFASMGGLAVGFGAQSLIKDLINGFFILFEDQFGVGDHITVGTFNGIVESI
GIRTTIIKDFTGDIHSIPNGSIIQVTNHSRGNIRFIVDVDIAYEENIDNAISIIKEVCSNFEQDNEDIREPIEVLGVNAL
NASSVTIRVIGKSKPLKQWEMERELRKLIKLRLDKEGIEIPYPKTQLVSANMEKGDL

Specific function: May play a role in resistance to osmotic downshock [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI87081787, Length=263, Percent_Identity=29.6577946768061, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1786670, Length=171, Percent_Identity=25.1461988304094, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI2367355, Length=295, Percent_Identity=24.0677966101695, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 33381; Mature: 33381

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINYLIKFDWNQEEIKIGKILIKLSNIETLINKTLIIIGVFILMYISIKIGNYLIRKFVE
CCEEEEEECCCHHHEEEEHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQVKSNTRLSLDSQRAKTLGEVMKSVLKYAVYFIGIASIISTLFKGLSFTFASMGGLAVG
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEC
FGAQSLIKDLINGFFILFEDQFGVGDHITVGTFNGIVESIGIRTTIIKDFTGDIHSIPNG
CCHHHHHHHHHCCEEEEEECCCCCCCEEEECHHHHHHHHHCCHHHHHHHHCCCHHCCCCC
SIIQVTNHSRGNIRFIVDVDIAYEENIDNAISIIKEVCSNFEQDNEDIREPIEVLGVNAL
CEEEEECCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCC
NASSVTIRVIGKSKPLKQWEMERELRKLIKLRLDKEGIEIPYPKTQLVSANMEKGDL
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEEECCCCCCCC
>Mature Secondary Structure
MINYLIKFDWNQEEIKIGKILIKLSNIETLINKTLIIIGVFILMYISIKIGNYLIRKFVE
CCEEEEEECCCHHHEEEEHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQVKSNTRLSLDSQRAKTLGEVMKSVLKYAVYFIGIASIISTLFKGLSFTFASMGGLAVG
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEC
FGAQSLIKDLINGFFILFEDQFGVGDHITVGTFNGIVESIGIRTTIIKDFTGDIHSIPNG
CCHHHHHHHHHCCEEEEEECCCCCCCEEEECHHHHHHHHHCCHHHHHHHHCCCHHCCCCC
SIIQVTNHSRGNIRFIVDVDIAYEENIDNAISIIKEVCSNFEQDNEDIREPIEVLGVNAL
CEEEEECCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCC
NASSVTIRVIGKSKPLKQWEMERELRKLIKLRLDKEGIEIPYPKTQLVSANMEKGDL
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]