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The map label for this gene is cobT [H]

Identifier: 187932988

GI number: 187932988

Start: 3010381

End: 3011472

Strand: Reverse

Name: cobT [H]

Synonym: CLL_A2928

Alternate gene names: 187932988

Gene position: 3011472-3010381 (Counterclockwise)

Preceding gene: 187933316

Following gene: 187933279

Centisome position: 79.24

GC content: 28.85

Gene sequence:

>1092_bases
ATGAAAAGTAAAGAAGAAATTCTTAGAGAAATTATAAGCAATATAGATAGTGTAGATAAAAATGTTATGGAAAAAGCAAA
AGAAAGAATGAATTCTCTTGCAAAACCACTAAATAGTTTAGGGAAACTTGAAGAAATGTCTATAAGGCTTTCAGGAATTA
CAGGAAGTATAAAAAATACTTTAGATAAAAGAGCAATTATTATTATGTGTTCAGATAATGGTGTTGTAGAAGAAGGAGTA
TCTTCATGTCCACAATCTGTAACATTATCTCAAACAATAAATTTCACTAAAGGTTTAACAGGAGTGGCAGTCCTTGCAAA
AGCTAATAATACAGATTTAAAAGTCATAGATGTAGGAATAAATAGTGATTTTAATCATCCACTAGTTTTAAATAGAAAGA
TAAGAAAATCTACAAATAACATATCTAAGGAAAATGCAATGACTTATGAAGAAGCTATTAATGCAATATTAGTTGGAATT
GAAGCTGTGAAAAACGCCAAAGAAGAAGGTTATAAAATACTTGGAGTTGGAGAGATGGGAATAGGTAATACTTCAACAAG
TAGTGCTGTTATATCATCATTAACAGGATGTAAAGTAGAAGATGTTGTAGGATATGGAGGGGGTATTTTAGAGAAGGCTT
ATAAAAAGAAAATAGAAGTAGTTAAAAAATCAATAGACATAAATAAGCCTAAAAAAGATGATCCTATAGATATACTATCT
AAAGTTGGAGGATTTGATATAGCAGCAATGGTAGGAGTATTTTTAGGAGCAGCATATTACAAAATACCTATTGTAATTGA
TGGATTTATATCAGTAGTTTCAGCACTAGTAGCATTTAGATTAAATCATAAAACTAAAGAATATATGTTTACTTCTCATA
GTTCAAAAGAAATTGGTTTTAAGACTGCAATGAAGGAACTTGAATTAGATGCTATATTAAATTTAGATATGGGACTTGGA
GAAGGTAGCGGATGTCCATTAGCATTTTCAATAATGGATTCAGCATGTGCTATTATGAATAATATGGCTACATTTGCAGA
AGCAGAAATAAATGATAGTTATTTAGATGAATTAAGAAAAATTAATAATTAA

Upstream 100 bases:

>100_bases
AATTAATAGTTATAGAAAAACCGAAATTTAAATATGATTTAGAATTTAATGATGAAGAAAGTTTAGTTTCTTTTTTAGTA
CATGAATTGGGGGGGAAGTT

Downstream 100 bases:

>100_bases
ATTTTTTCTTACAGTTTTTTAGCCAGTTTATTTTTCTTTTGTAGAAATTATAGAATAGTATGTTTAATTGAGAAAAAATA
TTTATTTTATAATATGTGTT

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MKSKEEILREIISNIDSVDKNVMEKAKERMNSLAKPLNSLGKLEEMSIRLSGITGSIKNTLDKRAIIIMCSDNGVVEEGV
SSCPQSVTLSQTINFTKGLTGVAVLAKANNTDLKVIDVGINSDFNHPLVLNRKIRKSTNNISKENAMTYEEAINAILVGI
EAVKNAKEEGYKILGVGEMGIGNTSTSSAVISSLTGCKVEDVVGYGGGILEKAYKKKIEVVKKSIDINKPKKDDPIDILS
KVGGFDIAAMVGVFLGAAYYKIPIVIDGFISVVSALVAFRLNHKTKEYMFTSHSSKEIGFKTAMKELELDAILNLDMGLG
EGSGCPLAFSIMDSACAIMNNMATFAEAEINDSYLDELRKINN

Sequences:

>Translated_363_residues
MKSKEEILREIISNIDSVDKNVMEKAKERMNSLAKPLNSLGKLEEMSIRLSGITGSIKNTLDKRAIIIMCSDNGVVEEGV
SSCPQSVTLSQTINFTKGLTGVAVLAKANNTDLKVIDVGINSDFNHPLVLNRKIRKSTNNISKENAMTYEEAINAILVGI
EAVKNAKEEGYKILGVGEMGIGNTSTSSAVISSLTGCKVEDVVGYGGGILEKAYKKKIEVVKKSIDINKPKKDDPIDILS
KVGGFDIAAMVGVFLGAAYYKIPIVIDGFISVVSALVAFRLNHKTKEYMFTSHSSKEIGFKTAMKELELDAILNLDMGLG
EGSGCPLAFSIMDSACAIMNNMATFAEAEINDSYLDELRKINN
>Mature_363_residues
MKSKEEILREIISNIDSVDKNVMEKAKERMNSLAKPLNSLGKLEEMSIRLSGITGSIKNTLDKRAIIIMCSDNGVVEEGV
SSCPQSVTLSQTINFTKGLTGVAVLAKANNTDLKVIDVGINSDFNHPLVLNRKIRKSTNNISKENAMTYEEAINAILVGI
EAVKNAKEEGYKILGVGEMGIGNTSTSSAVISSLTGCKVEDVVGYGGGILEKAYKKKIEVVKKSIDINKPKKDDPIDILS
KVGGFDIAAMVGVFLGAAYYKIPIVIDGFISVVSALVAFRLNHKTKEYMFTSHSSKEIGFKTAMKELELDAILNLDMGLG
EGSGCPLAFSIMDSACAIMNNMATFAEAEINDSYLDELRKINN

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=347, Percent_Identity=39.4812680115274, Blast_Score=274, Evalue=7e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 39235; Mature: 39235

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSKEEILREIISNIDSVDKNVMEKAKERMNSLAKPLNSLGKLEEMSIRLSGITGSIKNT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEEEECCCCHHHHC
LDKRAIIIMCSDNGVVEEGVSSCPQSVTLSQTINFTKGLTGVAVLAKANNTDLKVIDVGI
CCCCEEEEEECCCCCHHHHHHHCCCCEEHHHHHHHHCCCCCEEEEEECCCCCEEEEEEEC
NSDFNHPLVLNRKIRKSTNNISKENAMTYEEAINAILVGIEAVKNAKEEGYKILGVGEMG
CCCCCCCEEECHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCC
IGNTSTSSAVISSLTGCKVEDVVGYGGGILEKAYKKKIEVVKKSIDINKPKKDDPIDILS
CCCCCHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
KVGGFDIAAMVGVFLGAAYYKIPIVIDGFISVVSALVAFRLNHKTKEYMFTSHSSKEIGF
HCCCCHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHCCCHHHHEEECCCCCHHHH
KTAMKELELDAILNLDMGLGEGSGCPLAFSIMDSACAIMNNMATFAEAEINDSYLDELRK
HHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
INN
CCC
>Mature Secondary Structure
MKSKEEILREIISNIDSVDKNVMEKAKERMNSLAKPLNSLGKLEEMSIRLSGITGSIKNT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEEEECCCCHHHHC
LDKRAIIIMCSDNGVVEEGVSSCPQSVTLSQTINFTKGLTGVAVLAKANNTDLKVIDVGI
CCCCEEEEEECCCCCHHHHHHHCCCCEEHHHHHHHHCCCCCEEEEEECCCCCEEEEEEEC
NSDFNHPLVLNRKIRKSTNNISKENAMTYEEAINAILVGIEAVKNAKEEGYKILGVGEMG
CCCCCCCEEECHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCC
IGNTSTSSAVISSLTGCKVEDVVGYGGGILEKAYKKKIEVVKKSIDINKPKKDDPIDILS
CCCCCHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
KVGGFDIAAMVGVFLGAAYYKIPIVIDGFISVVSALVAFRLNHKTKEYMFTSHSSKEIGF
HCCCCHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHCCCHHHHEEECCCCCHHHH
KTAMKELELDAILNLDMGLGEGSGCPLAFSIMDSACAIMNNMATFAEAEINDSYLDELRK
HHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
INN
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA