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The map label for this gene is infC [H]

Identifier: 187932865

GI number: 187932865

Start: 2571705

End: 2572226

Strand: Reverse

Name: infC [H]

Synonym: CLL_A2479

Alternate gene names: 187932865

Gene position: 2572226-2571705 (Counterclockwise)

Preceding gene: 187935461

Following gene: 187932485

Centisome position: 67.68

GC content: 30.46

Gene sequence:

>522_bases
GTGAAAAGTATTAGTAAAGATTATTTTATTAATGAAGAGATAAGACAAAAAGAATTAAGAGTAGTTGCAAATGATGGAGA
ACAATTAGGTGTAATTTCTTCAAGAGAAGCTATGAGAATGGCAGAAGAACAAGAATTAGATTTAGTTATGATTTCACCAA
ATGCAAACCCTCCAGTATGTAAAATAATGGACTTTGGTAAGTTCATATATGAACAATCTAAAAAAGAAAAAGAAGCTAAG
AAGAAACAAAAGGTTGTAAGTGTTAAAGAAGTAAGAGTAAGTCTTACTATAGAAGAACATGATATTTTTATAAAAGCAAA
GAATGCCAGAAAATTCTTATTAGACGGAGATAAAGTTAAAATCACTGTTAGATTTAGAGGTAGAGAGATGGAATTGACTC
ATATTGGAGCAAGAATTCTTGATAACTTCGCAAAGAAATTGGAAGATGTCTGCCAAATAGAAAAGCATCCAAAAAAAGAA
GGCAGAAACATGACAATGGTTTTAGGCCCTAAAAAGGGATAA

Upstream 100 bases:

>100_bases
GTTGTGAAGTACTAGTGTGGTTATATCTCTAGATTTTATCAATAGTGATAGTGTAAGACGGCTTATGGCCGTCTTTTATT
ATGTATAAAATTCCTCGGAG

Downstream 100 bases:

>100_bases
CTTGAGAGGAGGATTTTATTTATGCCAAAAATGAAAAGCCACAGAGGTGCAGCAAAGAGATTTAAGAAAACAGGTACAGG
AAAGCTTAAGAGAGCGAAAG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MKSISKDYFINEEIRQKELRVVANDGEQLGVISSREAMRMAEEQELDLVMISPNANPPVCKIMDFGKFIYEQSKKEKEAK
KKQKVVSVKEVRVSLTIEEHDIFIKAKNARKFLLDGDKVKITVRFRGREMELTHIGARILDNFAKKLEDVCQIEKHPKKE
GRNMTMVLGPKKG

Sequences:

>Translated_173_residues
MKSISKDYFINEEIRQKELRVVANDGEQLGVISSREAMRMAEEQELDLVMISPNANPPVCKIMDFGKFIYEQSKKEKEAK
KKQKVVSVKEVRVSLTIEEHDIFIKAKNARKFLLDGDKVKITVRFRGREMELTHIGARILDNFAKKLEDVCQIEKHPKKE
GRNMTMVLGPKKG
>Mature_173_residues
MKSISKDYFINEEIRQKELRVVANDGEQLGVISSREAMRMAEEQELDLVMISPNANPPVCKIMDFGKFIYEQSKKEKEAK
KKQKVVSVKEVRVSLTIEEHDIFIKAKNARKFLLDGDKVKITVRFRGREMELTHIGARILDNFAKKLEDVCQIEKHPKKE
GRNMTMVLGPKKG

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=164, Percent_Identity=53.0487804878049, Blast_Score=151, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 19978; Mature: 19978

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSISKDYFINEEIRQKELRVVANDGEQLGVISSREAMRMAEEQELDLVMISPNANPPVC
CCCCCCCCEECHHHHHHHEEEEECCCCEECEECCHHHHHHHHHCCCCEEEECCCCCCCEE
KIMDFGKFIYEQSKKEKEAKKKQKVVSVKEVRVSLTIEEHDIFIKAKNARKFLLDGDKVK
EHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEECEEEEEECCCEEEEECCCEEE
ITVRFRGREMELTHIGARILDNFAKKLEDVCQIEKHPKKEGRNMTMVLGPKKG
EEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCEEEEEEECCCC
>Mature Secondary Structure
MKSISKDYFINEEIRQKELRVVANDGEQLGVISSREAMRMAEEQELDLVMISPNANPPVC
CCCCCCCCEECHHHHHHHEEEEECCCCEECEECCHHHHHHHHHCCCCEEEECCCCCCCEE
KIMDFGKFIYEQSKKEKEAKKKQKVVSVKEVRVSLTIEEHDIFIKAKNARKFLLDGDKVK
EHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEECEEEEEECCCEEEEECCCEEE
ITVRFRGREMELTHIGARILDNFAKKLEDVCQIEKHPKKEGRNMTMVLGPKKG
EEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11792842 [H]