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The map label for this gene is bltR [H]

Identifier: 187932463

GI number: 187932463

Start: 724600

End: 725427

Strand: Reverse

Name: bltR [H]

Synonym: CLL_A0723

Alternate gene names: 187932463

Gene position: 725427-724600 (Counterclockwise)

Preceding gene: 187933666

Following gene: 187933448

Centisome position: 19.09

GC content: 22.58

Gene sequence:

>828_bases
ATGAGCGAAAAATTAAAAAAATATTTTAATACTGGAGAATTTGCTAAACTATGTAATGTAAAAAAACAAACACTTTTTCA
TTATGATGCAATAGGAATTTTTTCGCCTGAGATAAAAGATAAAAATGGGTACAGATATTATTCACACCATCAATTTGAAA
TCTTTAATGTTATTATGATTCTAAAAGGAATTAATATGCCATTAAAAGATATTAAATCTTATCTTGATAATAGAACTCCT
GATTCATTAATTAATTTATTTAAAAATAAAATGTTAGAAATAGATAATGAAATTGAAAACTTAAATAGAATAAAAAAACT
TATGCAAACTAAAATAGATGTGACAGAAAAATCATGTAAAATTGATCCATTAAAGATATCTTTAGAATTTAAAGAAGAAG
AACATTTGATTCTTAGTAAATCTATAGAAAATGTTAGTTATAACGAATACCTAAGATCAGTATCAGAACATATGAAATAC
TGCACTTCAAATAAACTAAATACAAGTTATTCCCTTGGTGCAATGATAAATAAAAAAAATATTCTTCAGGGTGTAAAAGA
AAATTATTCTTATCTTTATACAAAAATAGATCCAAAATTAAATTGTAGTTCTATTTTTATTAAACCTAAAGGTATTTATG
CTATAGCTTATCATAAAGGAGGTTATGAAAATATTGATTATACATATAAAAAAATAATATCATTTTTAAATTCATTTAAC
CTTAATATTGGTGGTTATGCTTATGAAGAATACATTTTAGATGAAGCTTCCGTTATCGGATTTGAAAATTACTTAACAGA
AATTTCAGTTGAGGTTAATACTAAATAG

Upstream 100 bases:

>100_bases
TACCACATAAAATTTACATTATTGAAAAATCTTTATAGAAATATTATTATATAATCATAAGGTATATAGTAACCATATAG
TCAATAGGAGGATTAAAAAA

Downstream 100 bases:

>100_bases
ATTTCTAAGTGCTTAATTGAATTCATATATACAACATCAAATCTTGAAATAATTTCATCTTCTTATTGCATGTATTTTGG
TTATTTCATATATCAATTAA

Product: multidrug-efflux transporter 2 regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MSEKLKKYFNTGEFAKLCNVKKQTLFHYDAIGIFSPEIKDKNGYRYYSHHQFEIFNVIMILKGINMPLKDIKSYLDNRTP
DSLINLFKNKMLEIDNEIENLNRIKKLMQTKIDVTEKSCKIDPLKISLEFKEEEHLILSKSIENVSYNEYLRSVSEHMKY
CTSNKLNTSYSLGAMINKKNILQGVKENYSYLYTKIDPKLNCSSIFIKPKGIYAIAYHKGGYENIDYTYKKIISFLNSFN
LNIGGYAYEEYILDEASVIGFENYLTEISVEVNTK

Sequences:

>Translated_275_residues
MSEKLKKYFNTGEFAKLCNVKKQTLFHYDAIGIFSPEIKDKNGYRYYSHHQFEIFNVIMILKGINMPLKDIKSYLDNRTP
DSLINLFKNKMLEIDNEIENLNRIKKLMQTKIDVTEKSCKIDPLKISLEFKEEEHLILSKSIENVSYNEYLRSVSEHMKY
CTSNKLNTSYSLGAMINKKNILQGVKENYSYLYTKIDPKLNCSSIFIKPKGIYAIAYHKGGYENIDYTYKKIISFLNSFN
LNIGGYAYEEYILDEASVIGFENYLTEISVEVNTK
>Mature_274_residues
SEKLKKYFNTGEFAKLCNVKKQTLFHYDAIGIFSPEIKDKNGYRYYSHHQFEIFNVIMILKGINMPLKDIKSYLDNRTPD
SLINLFKNKMLEIDNEIENLNRIKKLMQTKIDVTEKSCKIDPLKISLEFKEEEHLILSKSIENVSYNEYLRSVSEHMKYC
TSNKLNTSYSLGAMINKKNILQGVKENYSYLYTKIDPKLNCSSIFIKPKGIYAIAYHKGGYENIDYTYKKIISFLNSFNL
NIGGYAYEEYILDEASVIGFENYLTEISVEVNTK

Specific function: Activates transcription of the blt gene in response to structurally dissimilar drugs [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR011256
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 32133; Mature: 32002

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKLKKYFNTGEFAKLCNVKKQTLFHYDAIGIFSPEIKDKNGYRYYSHHQFEIFNVIMI
CCHHHHHHHCCCHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCEEECCCHHHHHHHHHH
LKGINMPLKDIKSYLDNRTPDSLINLFKNKMLEIDNEIENLNRIKKLMQTKIDVTEKSCK
HHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
IDPLKISLEFKEEEHLILSKSIENVSYNEYLRSVSEHMKYCTSNKLNTSYSLGAMINKKN
CCEEEEEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEHHHHCCHHH
ILQGVKENYSYLYTKIDPKLNCSSIFIKPKGIYAIAYHKGGYENIDYTYKKIISFLNSFN
HHHHHHHCCEEEEEEECCCCCCCEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHCC
LNIGGYAYEEYILDEASVIGFENYLTEISVEVNTK
CCCCCEEHHHHHHCCHHHHHHHHHHEEEEEEEECC
>Mature Secondary Structure 
SEKLKKYFNTGEFAKLCNVKKQTLFHYDAIGIFSPEIKDKNGYRYYSHHQFEIFNVIMI
CHHHHHHHCCCHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCEEECCCHHHHHHHHHH
LKGINMPLKDIKSYLDNRTPDSLINLFKNKMLEIDNEIENLNRIKKLMQTKIDVTEKSCK
HHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
IDPLKISLEFKEEEHLILSKSIENVSYNEYLRSVSEHMKYCTSNKLNTSYSLGAMINKKN
CCEEEEEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEHHHHCCHHH
ILQGVKENYSYLYTKIDPKLNCSSIFIKPKGIYAIAYHKGGYENIDYTYKKIISFLNSFN
HHHHHHHCCEEEEEEECCCCCCCEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHCC
LNIGGYAYEEYILDEASVIGFENYLTEISVEVNTK
CCCCCEEHHHHHHCCHHHHHHHHHHEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7608059; 8969508; 9384377 [H]