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The map label for this gene is ywkD [H]

Identifier: 187932324

GI number: 187932324

Start: 2162745

End: 2163125

Strand: Reverse

Name: ywkD [H]

Synonym: CLL_A2068

Alternate gene names: 187932324

Gene position: 2163125-2162745 (Counterclockwise)

Preceding gene: 187933261

Following gene: 187932955

Centisome position: 56.92

GC content: 30.18

Gene sequence:

>381_bases
ATGAATTTAAACACAATTCACCATGTAGCAATAATAGTTTCGGATTATGAAAAATCTAAAGATTTTTATGTAAATAAGTT
AGGATTTAATATAATCAGGGAAAATTATAGACCTGATAGAGGTGATTATAAGTTAGATTTAAAACTTGGAGACTGTGAGC
TTGAGATATTTGGTATGGAGGATAGTCCTAAAAGGGTATCAAGACCAGAAGCCTGTGGATTAAGACATTTAGCTTTTAAA
GTGGAATGCATAGAAGATATAATAAGTGAATTAAATGAAAAGGGCATAGAAACAGAGCCCATAAGAATAGATGAATTTAC
GAATAAGAAAATGACATTTTTCTTTGATCCAGATGGACTACCTTTAGAATTACATGAGTAA

Upstream 100 bases:

>100_bases
TGAAAAATTAATAACGAGAGATTATTATTATATAGATAAAACATTATTATAATTATTAATTGGAATTTACTGCACTAAAG
GGGGAGGAGATGATAAAAAC

Downstream 100 bases:

>100_bases
AAAGTTTGGTTACATAAAAAATCACAAAAGTATCAGTATTAAATAAGTACTGGTGTTTTTTATTTGTTATAGTTTAATAC
TCATACTTGTTAGGGTATAA

Product: glyoxalase I

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MNLNTIHHVAIIVSDYEKSKDFYVNKLGFNIIRENYRPDRGDYKLDLKLGDCELEIFGMEDSPKRVSRPEACGLRHLAFK
VECIEDIISELNEKGIETEPIRIDEFTNKKMTFFFDPDGLPLELHE

Sequences:

>Translated_126_residues
MNLNTIHHVAIIVSDYEKSKDFYVNKLGFNIIRENYRPDRGDYKLDLKLGDCELEIFGMEDSPKRVSRPEACGLRHLAFK
VECIEDIISELNEKGIETEPIRIDEFTNKKMTFFFDPDGLPLELHE
>Mature_126_residues
MNLNTIHHVAIIVSDYEKSKDFYVNKLGFNIIRENYRPDRGDYKLDLKLGDCELEIFGMEDSPKRVSRPEACGLRHLAFK
VECIEDIISELNEKGIETEPIRIDEFTNKKMTFFFDPDGLPLELHE

Specific function: Unknown

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI87081697, Length=127, Percent_Identity=49.6062992125984, Blast_Score=129, Evalue=8e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: NA

Molecular weight: Translated: 14723; Mature: 14723

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00934 GLYOXALASE_I_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLNTIHHVAIIVSDYEKSKDFYVNKLGFNIIRENYRPDRGDYKLDLKLGDCELEIFGME
CCCCCEEEEEEEEECCCCCCCEEEEHHHHHHHHCCCCCCCCCEEEEEEECCEEEEEEECC
DSPKRVSRPEACGLRHLAFKVECIEDIISELNEKGIETEPIRIDEFTNKKMTFFFDPDGL
CCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEECCCCC
PLELHE
EEEECC
>Mature Secondary Structure
MNLNTIHHVAIIVSDYEKSKDFYVNKLGFNIIRENYRPDRGDYKLDLKLGDCELEIFGME
CCCCCEEEEEEEEECCCCCCCEEEEHHHHHHHHCCCCCCCCCEEEEEEECCEEEEEEECC
DSPKRVSRPEACGLRHLAFKVECIEDIISELNEKGIETEPIRIDEFTNKKMTFFFDPDGL
CCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEECCCCC
PLELHE
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]