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The map label for this gene is yafC [H]

Identifier: 187930592

GI number: 187930592

Start: 3698433

End: 3699329

Strand: Reverse

Name: yafC [H]

Synonym: Rpic_3528

Alternate gene names: 187930592

Gene position: 3699329-3698433 (Counterclockwise)

Preceding gene: 187930594

Following gene: 187930590

Centisome position: 93.83

GC content: 66.67

Gene sequence:

>897_bases
ATGAGCGGATCAGAACCGGGTTGGGAGTTGTATCGGACGTTTCTTGCCGTCGTGCGAGAAGGATCGCTGTCGGGCGCCGC
CCGCGCGTTGGGGCTGACGCAGCCGACCGTGGGGCGACATGTCGATGCGCTCGAACGGGCGCTGGGCATGTCGCTCTTCC
TCCGAACGCAGCAAGGGCTGAGCCCCACAGAAGCGGCGCTATCGCTGCGGCCGTTTGCGGAATCGCTCGAAGCCACGAGC
GCCGCCTTGCTGCGCGCCGCTTCCAGCCAGGGCGAGGGCGTGCGCGGCACCGTGCGCATCACTGCCAGCGAGGTGGTGGC
GGTGGAAGTGTTGCCGCCCATCCTCGCCGACCTGCACGCCGCCTATCCGGAGCTGACGCTCGAACTGGTGCCCTCCAACC
GGATGGAAGACCTGCTGCGCCGCGAGGCGGATATCGCCGTGCGCATGCAGCCACCGAGCCAGGGCGTGCTCGTCGCGCGG
CACATCGGCGCGATCGAGCTGGGGATATTTGCCCACCGGCGCTATCTGGCGCAGCGCGGCACGCCAAGCACGGTGGAAGA
ACTCGCGGCCCACACCTTGATCGGCTACGACAAAGAGAACGCGTTCCTGCGCAGCATGCGAGCGCAACTGCCGTGGGTTC
AACGCAACCGCTTCGCACTGCGCACCGACAGTGACCTGGCTGCGATTGCCGCGCTGCGTGCGGGCTTTGGCATCGGCTTC
TGCCAGATCGGGCTGGTGCGGAACAACGCAGATCTGGTTCGGCTGTTCGGCGATCAGATTTCCATCACGCTCGACACCTG
GCTCGCCATGCACGAAGACCTGCGTGACAGCCCGCGCTGCCGCGTGGTGTTTGATGCGCTGGCGACGGGGCTGCTGCGTT
ACATCAACGGCGATTGA

Upstream 100 bases:

>100_bases
TGCTCCTGATGTGAGAGAGAGCGTTGCGATGGAGGCATTCTGGGCGCAGCTATGCTTCAATGGAATTGTTGATATCAAGC
GTACAGCTATACAAATTTGT

Downstream 100 bases:

>100_bases
TCGATCGCGTTGTCAGCGGCCCTGGCGCAGTGGGTCGAGCAGGCCCTTCAGGCCGTTGTGATCCAGCTCCTGCATCAGCG
CCAGCAGTCGGCCGATCTGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MSGSEPGWELYRTFLAVVREGSLSGAARALGLTQPTVGRHVDALERALGMSLFLRTQQGLSPTEAALSLRPFAESLEATS
AALLRAASSQGEGVRGTVRITASEVVAVEVLPPILADLHAAYPELTLELVPSNRMEDLLRREADIAVRMQPPSQGVLVAR
HIGAIELGIFAHRRYLAQRGTPSTVEELAAHTLIGYDKENAFLRSMRAQLPWVQRNRFALRTDSDLAAIAALRAGFGIGF
CQIGLVRNNADLVRLFGDQISITLDTWLAMHEDLRDSPRCRVVFDALATGLLRYINGD

Sequences:

>Translated_298_residues
MSGSEPGWELYRTFLAVVREGSLSGAARALGLTQPTVGRHVDALERALGMSLFLRTQQGLSPTEAALSLRPFAESLEATS
AALLRAASSQGEGVRGTVRITASEVVAVEVLPPILADLHAAYPELTLELVPSNRMEDLLRREADIAVRMQPPSQGVLVAR
HIGAIELGIFAHRRYLAQRGTPSTVEELAAHTLIGYDKENAFLRSMRAQLPWVQRNRFALRTDSDLAAIAALRAGFGIGF
CQIGLVRNNADLVRLFGDQISITLDTWLAMHEDLRDSPRCRVVFDALATGLLRYINGD
>Mature_297_residues
SGSEPGWELYRTFLAVVREGSLSGAARALGLTQPTVGRHVDALERALGMSLFLRTQQGLSPTEAALSLRPFAESLEATSA
ALLRAASSQGEGVRGTVRITASEVVAVEVLPPILADLHAAYPELTLELVPSNRMEDLLRREADIAVRMQPPSQGVLVARH
IGAIELGIFAHRRYLAQRGTPSTVEELAAHTLIGYDKENAFLRSMRAQLPWVQRNRFALRTDSDLAAIAALRAGFGIGFC
QIGLVRNNADLVRLFGDQISITLDTWLAMHEDLRDSPRCRVVFDALATGLLRYINGD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=183, Percent_Identity=33.3333333333333, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1789639, Length=242, Percent_Identity=25.2066115702479, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI157672245, Length=141, Percent_Identity=32.6241134751773, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787128, Length=264, Percent_Identity=25.3787878787879, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787589, Length=187, Percent_Identity=28.8770053475936, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790208, Length=143, Percent_Identity=30.7692307692308, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI145693193, Length=183, Percent_Identity=25.6830601092896, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788748, Length=167, Percent_Identity=27.5449101796407, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32479; Mature: 32348

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSEPGWELYRTFLAVVREGSLSGAARALGLTQPTVGRHVDALERALGMSLFLRTQQGL
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEHHHCCC
SPTEAALSLRPFAESLEATSAALLRAASSQGEGVRGTVRITASEVVAVEVLPPILADLHA
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHEEEHHHHHHHHHHHHH
AYPELTLELVPSNRMEDLLRREADIAVRMQPPSQGVLVARHIGAIELGIFAHRRYLAQRG
CCCCEEEEECCCHHHHHHHHHCCCEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHCC
TPSTVEELAAHTLIGYDKENAFLRSMRAQLPWVQRNRFALRTDSDLAAIAALRAGFGIGF
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHCCCEEEECCCHHHHHHHHHHCCCCCE
CQIGLVRNNADLVRLFGDQISITLDTWLAMHEDLRDSPRCRVVFDALATGLLRYINGD
EEEEEEECCCCEEEEECCEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SGSEPGWELYRTFLAVVREGSLSGAARALGLTQPTVGRHVDALERALGMSLFLRTQQGL
CCCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEHHHCCC
SPTEAALSLRPFAESLEATSAALLRAASSQGEGVRGTVRITASEVVAVEVLPPILADLHA
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHEEEHHHHHHHHHHHHH
AYPELTLELVPSNRMEDLLRREADIAVRMQPPSQGVLVARHIGAIELGIFAHRRYLAQRG
CCCCEEEEECCCHHHHHHHHHCCCEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHCC
TPSTVEELAAHTLIGYDKENAFLRSMRAQLPWVQRNRFALRTDSDLAAIAALRAGFGIGF
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHCCCEEEECCCHHHHHHHHHHCCCCCE
CQIGLVRNNADLVRLFGDQISITLDTWLAMHEDLRDSPRCRVVFDALATGLLRYINGD
EEEEEEECCCCEEEEECCEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]