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The map label for this gene is tcp [H]

Identifier: 187930566

GI number: 187930566

Start: 3670666

End: 3672468

Strand: Reverse

Name: tcp [H]

Synonym: Rpic_3501

Alternate gene names: 187930566

Gene position: 3672468-3670666 (Counterclockwise)

Preceding gene: 187930568

Following gene: 187930564

Centisome position: 93.15

GC content: 65.72

Gene sequence:

>1803_bases
ATGATCTCCTCCCTCCGCACCCGCATTCTCTTCATCTCATCGGCCACCGTGGTTGGTGCCCTGGCGCTGTCTGGGGCCGC
AACGTATTCCATCGTGCGTTCCAACACGATGGAATCGATCGACCAGAACCTGGCCGCCGTTGCCAGCGGCAACACGCTCG
CCATCGACAAGTGGGTCGGGGCAAAGGCACAGGCCGTGAAGGCCACCGCCGGCGTGATCGAGCACGGTGACCCGCAAGGC
TTCGGCAAGCACATGGGCGATGCCAACGGCTTCCCGATCATCACGATCGGCTGGACCGACAAGAGCTTCATCTCCACCAG
CGCCACCACGCCCAAGGACTACGATCCGACCGGCCGCCCCTGGTACAAGCAGGCAATCGCTGCGGGCCAACTGCTCGTCA
CCAAGCCCTACGGCGACGTGTCGACCGGCGTGCCGTACGTGTCGTTTGCTGCGCCGCTCGTCAAGAATGGCGAAACCACC
GGTGCGTTGTCCGGGGCTGTGCCGCTCGACGGCGTGCGCGAGGTGGTCGCGGCGGTACACCCGACACCGTCGAGCCTCGC
CTTCGTGGTCGCCAAGGATGGCCAGGTGATCGCTCACCCTGACGCAAAGCTGATGCTCAAGCCGGCCACCGACGTTGCGC
CGTCGCTCACCGTCGATACGCTCGCCAACCTGGCCAAGGCGACGTCGCCGCTGGAGGTTGAACTGGCCGGCGCGCCGAAA
CTGCTCAAGGCGCAGGCCGTGCAGGGCACCGACTGGTATCTTGTAATCGCGCTGGACAAGGCCGAAGCCACCGCCGGTTT
GCGTAACGTCGTCAAGGCGCTGGCCGTGGCCATGGTGCTGCTGACGCTGGCCGCTGTGGGCATTGCCGCGTTCTTCACGT
CGCAATCGTTCCGCCGCCTGTCGCAGGTGCGCGATGCGATGGACACCATCGGCTCCGGCGGCGGCGACCTGACGCACCGC
CTGCCCGTGGTCGGCAACGATGAAGTCGCGCAGATCAGCGCGTCGTTCAACACCTTCATCGACAAGATTGGCGAAGTGCT
GCTGGAAGTGCGCGCCAGCGTCGACAGCATGAAATCCGCCACCGGCGAGATCGAAGCGGGCAACCGCGATCTCTCCAACC
GGACCGAGGTTTCGGCCAGCAACCTGCAGGAAACCTCTGCCGCGTTGACGGAGCTGACGACCAGCGTGAAGAACTCTGCC
GATGCGGCCGTGCAGGCCACGCGCCTGGCCAGCGACGCAAGCGATGCCGCCACGCGCGGCGGCGAGGTGGTTTCCAGCGC
CGTCAGCACGATGGACGAAATCGCCAAGTCGTCGGCGCGCATTACCGAGATCATCGGCGTGATCGACAGCATTGCGTTCC
AGACCAACATCCTCGCGCTGAACGCTGCAGTGGAAGCGGCCCGCGCCGGCGAGAACGGCCGCGGCTTTGCCGTGGTGGCC
GGCGAGGTGCGCACGCTGGCACAACGCAGCGCTACGGCCGCGCGCGAAATCAAAGACCTGATCCAGGCATCGGAAGCCAG
CGTGAAGACCGGCGCGCAACGCGTGCAGGCCGCCGGCGCAACGATGCAGGAAATCGTGCAGGGCATCGAACGTGTGGCGC
GCATCATCGGCGAGATCGACGGCGCGATGCACGAGCAGAGCACTGGCATCAGCCAGATCGATCGCAGCGTCGCCGAGATG
GATCAGGCCACGCAGCAGAACGCGGCACTGGTGGAGCAGTCGACGGCTGCATCGTCCATGCTCAACGAACAGGCGCACGG
CCTGGCTCGCACGGTTGGGCTGTTCAAGTTGCGCAACGTCTGA

Upstream 100 bases:

>100_bases
AGCTTGAGTGGCCCCGACAGTCAGCAGTCGGTTCTGGAGGGCGCTGCGGCCAATACCGTACGCAGTCAGATTCATGGAAA
ACGTTTCGCCTAGAAGAATC

Downstream 100 bases:

>100_bases
CGCGCCGCTACATTGACCGCCCGTCAAAGTGGGTGACCGGCACGCTGGTCAGATCGATGTCTTCCAGGCAGCGGACGTTG
ACGGCAATCATTGGTGTGCC

Product: Cache sensor-containing methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 600; Mature: 600

Protein sequence:

>600_residues
MISSLRTRILFISSATVVGALALSGAATYSIVRSNTMESIDQNLAAVASGNTLAIDKWVGAKAQAVKATAGVIEHGDPQG
FGKHMGDANGFPIITIGWTDKSFISTSATTPKDYDPTGRPWYKQAIAAGQLLVTKPYGDVSTGVPYVSFAAPLVKNGETT
GALSGAVPLDGVREVVAAVHPTPSSLAFVVAKDGQVIAHPDAKLMLKPATDVAPSLTVDTLANLAKATSPLEVELAGAPK
LLKAQAVQGTDWYLVIALDKAEATAGLRNVVKALAVAMVLLTLAAVGIAAFFTSQSFRRLSQVRDAMDTIGSGGGDLTHR
LPVVGNDEVAQISASFNTFIDKIGEVLLEVRASVDSMKSATGEIEAGNRDLSNRTEVSASNLQETSAALTELTTSVKNSA
DAAVQATRLASDASDAATRGGEVVSSAVSTMDEIAKSSARITEIIGVIDSIAFQTNILALNAAVEAARAGENGRGFAVVA
GEVRTLAQRSATAAREIKDLIQASEASVKTGAQRVQAAGATMQEIVQGIERVARIIGEIDGAMHEQSTGISQIDRSVAEM
DQATQQNAALVEQSTAASSMLNEQAHGLARTVGLFKLRNV

Sequences:

>Translated_600_residues
MISSLRTRILFISSATVVGALALSGAATYSIVRSNTMESIDQNLAAVASGNTLAIDKWVGAKAQAVKATAGVIEHGDPQG
FGKHMGDANGFPIITIGWTDKSFISTSATTPKDYDPTGRPWYKQAIAAGQLLVTKPYGDVSTGVPYVSFAAPLVKNGETT
GALSGAVPLDGVREVVAAVHPTPSSLAFVVAKDGQVIAHPDAKLMLKPATDVAPSLTVDTLANLAKATSPLEVELAGAPK
LLKAQAVQGTDWYLVIALDKAEATAGLRNVVKALAVAMVLLTLAAVGIAAFFTSQSFRRLSQVRDAMDTIGSGGGDLTHR
LPVVGNDEVAQISASFNTFIDKIGEVLLEVRASVDSMKSATGEIEAGNRDLSNRTEVSASNLQETSAALTELTTSVKNSA
DAAVQATRLASDASDAATRGGEVVSSAVSTMDEIAKSSARITEIIGVIDSIAFQTNILALNAAVEAARAGENGRGFAVVA
GEVRTLAQRSATAAREIKDLIQASEASVKTGAQRVQAAGATMQEIVQGIERVARIIGEIDGAMHEQSTGISQIDRSVAEM
DQATQQNAALVEQSTAASSMLNEQAHGLARTVGLFKLRNV
>Mature_600_residues
MISSLRTRILFISSATVVGALALSGAATYSIVRSNTMESIDQNLAAVASGNTLAIDKWVGAKAQAVKATAGVIEHGDPQG
FGKHMGDANGFPIITIGWTDKSFISTSATTPKDYDPTGRPWYKQAIAAGQLLVTKPYGDVSTGVPYVSFAAPLVKNGETT
GALSGAVPLDGVREVVAAVHPTPSSLAFVVAKDGQVIAHPDAKLMLKPATDVAPSLTVDTLANLAKATSPLEVELAGAPK
LLKAQAVQGTDWYLVIALDKAEATAGLRNVVKALAVAMVLLTLAAVGIAAFFTSQSFRRLSQVRDAMDTIGSGGGDLTHR
LPVVGNDEVAQISASFNTFIDKIGEVLLEVRASVDSMKSATGEIEAGNRDLSNRTEVSASNLQETSAALTELTTSVKNSA
DAAVQATRLASDASDAATRGGEVVSSAVSTMDEIAKSSARITEIIGVIDSIAFQTNILALNAAVEAARAGENGRGFAVVA
GEVRTLAQRSATAAREIKDLIQASEASVKTGAQRVQAAGATMQEIVQGIERVARIIGEIDGAMHEQSTGISQIDRSVAEM
DQATQQNAALVEQSTAASSMLNEQAHGLARTVGLFKLRNV

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=284, Percent_Identity=53.5211267605634, Blast_Score=250, Evalue=2e-67,
Organism=Escherichia coli, GI2367378, Length=285, Percent_Identity=53.3333333333333, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI1788194, Length=350, Percent_Identity=44.8571428571429, Blast_Score=242, Evalue=5e-65,
Organism=Escherichia coli, GI1787690, Length=326, Percent_Identity=45.398773006135, Blast_Score=239, Evalue=4e-64,
Organism=Escherichia coli, GI1789453, Length=240, Percent_Identity=45.8333333333333, Blast_Score=201, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 62134; Mature: 62134

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISSLRTRILFISSATVVGALALSGAATYSIVRSNTMESIDQNLAAVASGNTLAIDKWVG
CCCCCCEEEEEEECHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
AKAQAVKATAGVIEHGDPQGFGKHMGDANGFPIITIGWTDKSFISTSATTPKDYDPTGRP
CCHHHHHHHHHHHCCCCCCCHHHHCCCCCCCEEEEEECCCCHHEECCCCCCCCCCCCCCH
WYKQAIAAGQLLVTKPYGDVSTGVPYVSFAAPLVKNGETTGALSGAVPLDGVREVVAAVH
HHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCC
PTPSSLAFVVAKDGQVIAHPDAKLMLKPATDVAPSLTVDTLANLAKATSPLEVELAGAPK
CCCCCEEEEEECCCEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCH
LLKAQAVQGTDWYLVIALDKAEATAGLRNVVKALAVAMVLLTLAAVGIAAFFTSQSFRRL
HHHHHHCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQVRDAMDTIGSGGGDLTHRLPVVGNDEVAQISASFNTFIDKIGEVLLEVRASVDSMKSA
HHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TGEIEAGNRDLSNRTEVSASNLQETSAALTELTTSVKNSADAAVQATRLASDASDAATRG
CCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHCC
GEVVSSAVSTMDEIAKSSARITEIIGVIDSIAFQTNILALNAAVEAARAGENGRGFAVVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCEEEEEE
GEVRTLAQRSATAAREIKDLIQASEASVKTGAQRVQAAGATMQEIVQGIERVARIIGEID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
GAMHEQSTGISQIDRSVAEMDQATQQNAALVEQSTAASSMLNEQAHGLARTVGLFKLRNV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MISSLRTRILFISSATVVGALALSGAATYSIVRSNTMESIDQNLAAVASGNTLAIDKWVG
CCCCCCEEEEEEECHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
AKAQAVKATAGVIEHGDPQGFGKHMGDANGFPIITIGWTDKSFISTSATTPKDYDPTGRP
CCHHHHHHHHHHHCCCCCCCHHHHCCCCCCCEEEEEECCCCHHEECCCCCCCCCCCCCCH
WYKQAIAAGQLLVTKPYGDVSTGVPYVSFAAPLVKNGETTGALSGAVPLDGVREVVAAVH
HHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCC
PTPSSLAFVVAKDGQVIAHPDAKLMLKPATDVAPSLTVDTLANLAKATSPLEVELAGAPK
CCCCCEEEEEECCCEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCH
LLKAQAVQGTDWYLVIALDKAEATAGLRNVVKALAVAMVLLTLAAVGIAAFFTSQSFRRL
HHHHHHCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQVRDAMDTIGSGGGDLTHRLPVVGNDEVAQISASFNTFIDKIGEVLLEVRASVDSMKSA
HHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TGEIEAGNRDLSNRTEVSASNLQETSAALTELTTSVKNSADAAVQATRLASDASDAATRG
CCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHCC
GEVVSSAVSTMDEIAKSSARITEIIGVIDSIAFQTNILALNAAVEAARAGENGRGFAVVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCEEEEEE
GEVRTLAQRSATAAREIKDLIQASEASVKTGAQRVQAAGATMQEIVQGIERVARIIGEID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
GAMHEQSTGISQIDRSVAEMDQATQQNAALVEQSTAASSMLNEQAHGLARTVGLFKLRNV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]