Click here to switch to the map view.

The map label for this gene is tcp [H]

Identifier: 187930478

GI number: 187930478

Start: 3576654

End: 3578642

Strand: Reverse

Name: tcp [H]

Synonym: Rpic_3412

Alternate gene names: 187930478

Gene position: 3578642-3576654 (Counterclockwise)

Preceding gene: 187930479

Following gene: 187930477

Centisome position: 90.77

GC content: 67.02

Gene sequence:

>1989_bases
ATGAGAGCGTCTGCGCCCCTTTCTGAGGTTTCACAACCTCCAACAAGCCTCGGTACCAGGCTGGCGGTGATTGGCCTGAT
CGCCCTGGTGCTCGTGTTCGGCATGTTTGCCTTGGCGAACTCGCAATCGAGCCTGCGCATGCTGGAGGCCAATACACAAT
CGGCCATGCATAACCAGGAGGCCGCCATGCGCGACATGATCGGCCTGTTCGACGGCACCATGCGCACCGAGGCCGACCGC
TTCCTGACCGCTTTTGCCGACGCCGCGCCCGGGCCGTACAGCGTAGATCCGGCGCAGACCGTTGAAGTGGCCGGCAAGCC
GACGCCCACGTTCAAGAGCGGTGACACGGTGCTGAACCTCAACTTCACCGTGCCGGACCAGTTCTTCGCGCGCACCGGCG
GCACGATCGCCACCGTGTTTGCCCGGACCGGCGACGATTTCGTGCGCGTGACCACTTCGCTCAAGAAGGAAAACGGCGAA
CGCGCGATCGGCACGCTGCTTGATCGCGCCCACCCGAGCTACAAGGCGCTGATGGCCGGCGAGCCGTTCCGCGGCCTGGC
CTGGCTGTTTGGCGCGCCCTACATGAGCAAGTACGAACCCGTGCGCGATGCCTCGGGCAAGGTCATCGGCGCGCTCTACG
TAGGTGTGGACGTGCGCTCGGAACTGGCGCTGCTCAAGGACAAAATCCGCTCGCACGGCATCGGCAAGACGGGCGGCTAT
TTCGTTATCGACGGCAAGCCCGGCGCAGACCAGGGCAAGGTGCTGATCGACCACACGCAAGACCGCGAAGGCAAGAACCT
GCTCGACGCCAAGGACTCGGCCGGCCAGGCCTGGGTGCGCGAGATGATCGCGCGCAAGGACGGCACGTTGCGCCACACGC
TGGCCGACACGGAAGCTGGCACCGCGCGCGAGCGCCTGACCGTCTTCACCCAATACCCGGATTGGCAACTGGTGATTGCC
GGTACGGCCTATGTGGATGAACTGGACGCCGATCTGGTGGCTGCCCGCAACCGCTTTCTGCTGTTGGGTCTGGCACTCGG
CGCGCTGCTGGCCGGCGGCCTGTACTGGATGCTGCGCCGTACCGTGAGCACGCCGCTGGCCGAGGTGGTGAACGTCGCGC
AGCGTGTGGCTGCGGGCGATCTCACGCACCGCCTGCCCACCACGCGCAGCGATGAAATCGGCCAGGTCATGCGCGCCGTC
AATGGCGTTGGCGACGGCCTTTCGGGCATCGTCGACAAGGTGCGCGCCAGCGCCTCGACCATCGCGTCGAGCACGGGCCA
GATCGCCGCCGGCAACGCCGATCTTTCCGCGCGTACCGAAGCGCAGGCCGGCAACCTTGAGCGCACCGCATCGAGCATCG
AACAACTGGCCGCCACCGTGCGCCAGAACGCCGAGAGCGCGCACCACGCGCACGACATGGTGCAATCCGCCAGCGAGGCG
GCCAACGCAGGCGGGCAGACCGTGGAGCGGCTGGTCGGCACCATGTCGGGCATCCATGCCACGGCGCAGAAGATCGCCGA
CATCACCGGCATCATCGACGGCATCGCGTTCCAGACGAACATCCTGGCGCTGAACGCCGCCGTGGAAGCCGCCCGCGCAG
GCGAACAGGGCCGCGGCTTCGCTGTCGTCGCCGGCGAGGTGCGCAGCCTCGCCCAGCGCAGTGCAGCCGCCGCCAAGGAG
ATCAAGGAACTGATCAGTCGCTCGGTCGAAGAAGTGCAGGCCGGCAATGAAGCCGCCCGCGGCGCCGGTGACGCCATGCA
GGACATCGTGACGCGCGTGGAGCGCATCGCCGGCCTGATGGGCGAGATCAGCCACGCGTCGCGCGAGCAGTCGCAAGGCA
TCGAAGAGGTCAACCACGCGGTCACGGCGATGGACGAGGTGACGCAGCAGAACGCTGCGTTGGTCGAAGAAGCTGCCGCT
GCGGCCGAAAGCCTGCGCCAGCAAGCCCAGGAACTGCGCGGCGCGGTGGACGTGTTCCGGCTCGCCTGA

Upstream 100 bases:

>100_bases
CGTCTGGTCTGCCAGACATAAGGGGCTGCAAAACGTTTGCGCTCAAGCTTTTCTGGGTTGATCCGTTGTTAACTTGACTG
ACGACCCCCAGGAAAAAAGC

Downstream 100 bases:

>100_bases
AGCGGCAAGATGTCATGAACTAATGATGTGGTGTAGCAATCGGTACAAGGATTGACTGGCAATCGTGCAAACTTGTACCG
CGCGGAACCTGATCCGCACC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 662; Mature: 662

Protein sequence:

>662_residues
MRASAPLSEVSQPPTSLGTRLAVIGLIALVLVFGMFALANSQSSLRMLEANTQSAMHNQEAAMRDMIGLFDGTMRTEADR
FLTAFADAAPGPYSVDPAQTVEVAGKPTPTFKSGDTVLNLNFTVPDQFFARTGGTIATVFARTGDDFVRVTTSLKKENGE
RAIGTLLDRAHPSYKALMAGEPFRGLAWLFGAPYMSKYEPVRDASGKVIGALYVGVDVRSELALLKDKIRSHGIGKTGGY
FVIDGKPGADQGKVLIDHTQDREGKNLLDAKDSAGQAWVREMIARKDGTLRHTLADTEAGTARERLTVFTQYPDWQLVIA
GTAYVDELDADLVAARNRFLLLGLALGALLAGGLYWMLRRTVSTPLAEVVNVAQRVAAGDLTHRLPTTRSDEIGQVMRAV
NGVGDGLSGIVDKVRASASTIASSTGQIAAGNADLSARTEAQAGNLERTASSIEQLAATVRQNAESAHHAHDMVQSASEA
ANAGGQTVERLVGTMSGIHATAQKIADITGIIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRSLAQRSAAAAKE
IKELISRSVEEVQAGNEAARGAGDAMQDIVTRVERIAGLMGEISHASREQSQGIEEVNHAVTAMDEVTQQNAALVEEAAA
AAESLRQQAQELRGAVDVFRLA

Sequences:

>Translated_662_residues
MRASAPLSEVSQPPTSLGTRLAVIGLIALVLVFGMFALANSQSSLRMLEANTQSAMHNQEAAMRDMIGLFDGTMRTEADR
FLTAFADAAPGPYSVDPAQTVEVAGKPTPTFKSGDTVLNLNFTVPDQFFARTGGTIATVFARTGDDFVRVTTSLKKENGE
RAIGTLLDRAHPSYKALMAGEPFRGLAWLFGAPYMSKYEPVRDASGKVIGALYVGVDVRSELALLKDKIRSHGIGKTGGY
FVIDGKPGADQGKVLIDHTQDREGKNLLDAKDSAGQAWVREMIARKDGTLRHTLADTEAGTARERLTVFTQYPDWQLVIA
GTAYVDELDADLVAARNRFLLLGLALGALLAGGLYWMLRRTVSTPLAEVVNVAQRVAAGDLTHRLPTTRSDEIGQVMRAV
NGVGDGLSGIVDKVRASASTIASSTGQIAAGNADLSARTEAQAGNLERTASSIEQLAATVRQNAESAHHAHDMVQSASEA
ANAGGQTVERLVGTMSGIHATAQKIADITGIIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRSLAQRSAAAAKE
IKELISRSVEEVQAGNEAARGAGDAMQDIVTRVERIAGLMGEISHASREQSQGIEEVNHAVTAMDEVTQQNAALVEEAAA
AAESLRQQAQELRGAVDVFRLA
>Mature_662_residues
MRASAPLSEVSQPPTSLGTRLAVIGLIALVLVFGMFALANSQSSLRMLEANTQSAMHNQEAAMRDMIGLFDGTMRTEADR
FLTAFADAAPGPYSVDPAQTVEVAGKPTPTFKSGDTVLNLNFTVPDQFFARTGGTIATVFARTGDDFVRVTTSLKKENGE
RAIGTLLDRAHPSYKALMAGEPFRGLAWLFGAPYMSKYEPVRDASGKVIGALYVGVDVRSELALLKDKIRSHGIGKTGGY
FVIDGKPGADQGKVLIDHTQDREGKNLLDAKDSAGQAWVREMIARKDGTLRHTLADTEAGTARERLTVFTQYPDWQLVIA
GTAYVDELDADLVAARNRFLLLGLALGALLAGGLYWMLRRTVSTPLAEVVNVAQRVAAGDLTHRLPTTRSDEIGQVMRAV
NGVGDGLSGIVDKVRASASTIASSTGQIAAGNADLSARTEAQAGNLERTASSIEQLAATVRQNAESAHHAHDMVQSASEA
ANAGGQTVERLVGTMSGIHATAQKIADITGIIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRSLAQRSAAAAKE
IKELISRSVEEVQAGNEAARGAGDAMQDIVTRVERIAGLMGEISHASREQSQGIEEVNHAVTAMDEVTQQNAALVEEAAA
AAESLRQQAQELRGAVDVFRLA

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=336, Percent_Identity=50.8928571428571, Blast_Score=290, Evalue=2e-79,
Organism=Escherichia coli, GI1788195, Length=308, Percent_Identity=53.5714285714286, Blast_Score=275, Evalue=6e-75,
Organism=Escherichia coli, GI1788194, Length=323, Percent_Identity=49.2260061919505, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI2367378, Length=324, Percent_Identity=51.8518518518518, Blast_Score=266, Evalue=3e-72,
Organism=Escherichia coli, GI1789453, Length=318, Percent_Identity=40.5660377358491, Blast_Score=225, Evalue=7e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 69998; Mature: 69998

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRASAPLSEVSQPPTSLGTRLAVIGLIALVLVFGMFALANSQSSLRMLEANTQSAMHNQE
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AAMRDMIGLFDGTMRTEADRFLTAFADAAPGPYSVDPAQTVEVAGKPTPTFKSGDTVLNL
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHEECCCCCCCCCCCCEEEEE
NFTVPDQFFARTGGTIATVFARTGDDFVRVTTSLKKENGERAIGTLLDRAHPSYKALMAG
EECCCHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHCC
EPFRGLAWLFGAPYMSKYEPVRDASGKVIGALYVGVDVRSELALLKDKIRSHGIGKTGGY
CCCHHHHHHHCCCCHHHCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCE
FVIDGKPGADQGKVLIDHTQDREGKNLLDAKDSAGQAWVREMIARKDGTLRHTLADTEAG
EEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEHHHCCCCCC
TARERLTVFTQYPDWQLVIAGTAYVDELDADLVAARNRFLLLGLALGALLAGGLYWMLRR
CCHHHEEEEEECCCEEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
TVSTPLAEVVNVAQRVAAGDLTHRLPTTRSDEIGQVMRAVNGVGDGLSGIVDKVRASAST
HHHCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
IASSTGQIAAGNADLSARTEAQAGNLERTASSIEQLAATVRQNAESAHHAHDMVQSASEA
HHCCCCCEEECCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANAGGQTVERLVGTMSGIHATAQKIADITGIIDGIAFQTNILALNAAVEAARAGEQGRGF
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
AVVAGEVRSLAQRSAAAAKEIKELISRSVEEVQAGNEAARGAGDAMQDIVTRVERIAGLM
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHH
GEISHASREQSQGIEEVNHAVTAMDEVTQQNAALVEEAAAAAESLRQQAQELRGAVDVFR
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LA
CC
>Mature Secondary Structure
MRASAPLSEVSQPPTSLGTRLAVIGLIALVLVFGMFALANSQSSLRMLEANTQSAMHNQE
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AAMRDMIGLFDGTMRTEADRFLTAFADAAPGPYSVDPAQTVEVAGKPTPTFKSGDTVLNL
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHEECCCCCCCCCCCCEEEEE
NFTVPDQFFARTGGTIATVFARTGDDFVRVTTSLKKENGERAIGTLLDRAHPSYKALMAG
EECCCHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHCC
EPFRGLAWLFGAPYMSKYEPVRDASGKVIGALYVGVDVRSELALLKDKIRSHGIGKTGGY
CCCHHHHHHHCCCCHHHCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCE
FVIDGKPGADQGKVLIDHTQDREGKNLLDAKDSAGQAWVREMIARKDGTLRHTLADTEAG
EEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEHHHCCCCCC
TARERLTVFTQYPDWQLVIAGTAYVDELDADLVAARNRFLLLGLALGALLAGGLYWMLRR
CCHHHEEEEEECCCEEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
TVSTPLAEVVNVAQRVAAGDLTHRLPTTRSDEIGQVMRAVNGVGDGLSGIVDKVRASAST
HHHCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
IASSTGQIAAGNADLSARTEAQAGNLERTASSIEQLAATVRQNAESAHHAHDMVQSASEA
HHCCCCCEEECCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANAGGQTVERLVGTMSGIHATAQKIADITGIIDGIAFQTNILALNAAVEAARAGEQGRGF
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
AVVAGEVRSLAQRSAAAAKEIKELISRSVEEVQAGNEAARGAGDAMQDIVTRVERIAGLM
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHH
GEISHASREQSQGIEEVNHAVTAMDEVTQQNAALVEEAAAAAESLRQQAQELRGAVDVFR
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]