Click here to switch to the map view.

The map label for this gene is secY [H]

Identifier: 187930344

GI number: 187930344

Start: 3424413

End: 3425735

Strand: Reverse

Name: secY [H]

Synonym: Rpic_3277

Alternate gene names: 187930344

Gene position: 3425735-3424413 (Counterclockwise)

Preceding gene: 187930345

Following gene: 187930343

Centisome position: 86.89

GC content: 58.5

Gene sequence:

>1323_bases
ATGGCCCAGGCCAAGAACACGGCCAAGTACGGCGATCTTCGCCGTCGGCTGGTGTTCCTGGTGCTGGCATTGCTGGTGTA
CCGGATCGGCGCGCACATTCCTGTGCCGGGTATCGATCCGGATCAACTGGCGCAGCTTTTCCAACGGCAGTCGGGTGGCA
TCCTCGGGATGTTTAACCTGTTCTCCGGCGGCGCGCTGTCGCGTTTCACAGTGTTTGCGTTGGGGATCATGCCGTACATC
TCGGCGTCGATCATCATGCAGCTGCTGACGATCGTGCTGCCGCAGCTGGAATCGTTGAAGAAGGAAGGCCAGGCCGGCCA
GCGCAAGATTACGCAGTACACGCGCTACGGCACGGTCATCCTGGCGACGTTCCAGGCGCTAGGGATTGCAGTAGCCCTGG
AAGCGCAGCCCGGTCTGGTGCTGGATCCGGGTCTGATGTTCCGGGCCACCGCGGTGATCACGCTGGTGACGGGCACGATG
TTCCTGATGTGGCTGGGTGAGCAGATCACCGAGCGTGGTCTGGGCAACGGGATCTCGATCATCATTTTTGGCGGGATTGC
TGCAGGCCTTCCCAACGCGATTGGCGGGCTGTTCGAGCTGGTGCGTACGGGTTCGATGGGAATTTTCTCGGCGATCCTGG
TGGTGGCGATTATTGGTGCGGTGACGTTTGTGGTCGTGTTCATCGAACGCGGCCAGCGCAAGATCCTCGTCAATTACGCC
AAGCGGCAGGTTGGTAACAAGATTTATGGCGGACAGTCGTCGCATCTGCCGCTGAAGTTGAATATGGCCGGGGTGATTCC
GCCGATCTTTGCATCGTCGATCATTCTGTTCCCGGCCACGATCGCGGGCTGGTTTACAGCTGGCAACTCGACGAATCCGG
TGGCACGGGTTGTCAAGGACTTGGCAGCAACGCTGTCGCCGGGTCAGCCGGTCTACATCCTGCTGTATGCGGCGGCGATC
ATCTTCTTCTGTTTCTTCTACACCGCACTGGTTTATAACAGCCGGGAAGTGGCAGATAACCTGAAGAAGAGTGGGGCGTT
CATTCCGGGCATCCGTCCGGGCGAGCAAACCACGCGGTATATCGACAAGATTCTGGTGCGTCTGACCCTGGCGGGTGCGA
TCTACATCACGCTGGTGTGTCTGTTGCCGGAGTTCTTGGTGCTGCGCTGGAATGTGCCGTTCTACTTCGGTGGGACGTCC
CTGTTGATCATCGTGGTTGTCACGATGGACTTCATGGCGCAAGTGCAGTCCTACGTGATGTCTCAGCAGTACGAGTCTTT
GATGAAGAAGGCGAATTTCAAGGGAAACCTGACACTCCGCTAG

Upstream 100 bases:

>100_bases
GGCGAAAGCTGCAATCGAAGCAGCCGGTGGCTCGCTGGCCTAATAGCCTGCTGTTTCACACTGACGGAGCATCCGTTTGG
CCACGGCGAAACCTAATGTG

Downstream 100 bases:

>100_bases
GAGTGATCGCACGAACCTGAAAGGACATGGCTAAAGATGACGTGATCCAGATGCAAGGCGAGGTGCTGGAAAACCTCCCC
AACGCAACGTTTCGCGTCAA

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MAQAKNTAKYGDLRRRLVFLVLALLVYRIGAHIPVPGIDPDQLAQLFQRQSGGILGMFNLFSGGALSRFTVFALGIMPYI
SASIIMQLLTIVLPQLESLKKEGQAGQRKITQYTRYGTVILATFQALGIAVALEAQPGLVLDPGLMFRATAVITLVTGTM
FLMWLGEQITERGLGNGISIIIFGGIAAGLPNAIGGLFELVRTGSMGIFSAILVVAIIGAVTFVVVFIERGQRKILVNYA
KRQVGNKIYGGQSSHLPLKLNMAGVIPPIFASSIILFPATIAGWFTAGNSTNPVARVVKDLAATLSPGQPVYILLYAAAI
IFFCFFYTALVYNSREVADNLKKSGAFIPGIRPGEQTTRYIDKILVRLTLAGAIYITLVCLLPEFLVLRWNVPFYFGGTS
LLIIVVVTMDFMAQVQSYVMSQQYESLMKKANFKGNLTLR

Sequences:

>Translated_440_residues
MAQAKNTAKYGDLRRRLVFLVLALLVYRIGAHIPVPGIDPDQLAQLFQRQSGGILGMFNLFSGGALSRFTVFALGIMPYI
SASIIMQLLTIVLPQLESLKKEGQAGQRKITQYTRYGTVILATFQALGIAVALEAQPGLVLDPGLMFRATAVITLVTGTM
FLMWLGEQITERGLGNGISIIIFGGIAAGLPNAIGGLFELVRTGSMGIFSAILVVAIIGAVTFVVVFIERGQRKILVNYA
KRQVGNKIYGGQSSHLPLKLNMAGVIPPIFASSIILFPATIAGWFTAGNSTNPVARVVKDLAATLSPGQPVYILLYAAAI
IFFCFFYTALVYNSREVADNLKKSGAFIPGIRPGEQTTRYIDKILVRLTLAGAIYITLVCLLPEFLVLRWNVPFYFGGTS
LLIIVVVTMDFMAQVQSYVMSQQYESLMKKANFKGNLTLR
>Mature_439_residues
AQAKNTAKYGDLRRRLVFLVLALLVYRIGAHIPVPGIDPDQLAQLFQRQSGGILGMFNLFSGGALSRFTVFALGIMPYIS
ASIIMQLLTIVLPQLESLKKEGQAGQRKITQYTRYGTVILATFQALGIAVALEAQPGLVLDPGLMFRATAVITLVTGTMF
LMWLGEQITERGLGNGISIIIFGGIAAGLPNAIGGLFELVRTGSMGIFSAILVVAIIGAVTFVVVFIERGQRKILVNYAK
RQVGNKIYGGQSSHLPLKLNMAGVIPPIFASSIILFPATIAGWFTAGNSTNPVARVVKDLAATLSPGQPVYILLYAAAII
FFCFFYTALVYNSREVADNLKKSGAFIPGIRPGEQTTRYIDKILVRLTLAGAIYITLVCLLPEFLVLRWNVPFYFGGTSL
LIIVVVTMDFMAQVQSYVMSQQYESLMKKANFKGNLTLR

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=428, Percent_Identity=65.8878504672897, Blast_Score=531, Evalue=1e-152,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 47836; Mature: 47704

Theoretical pI: Translated: 10.38; Mature: 10.38

Prosite motif: PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQAKNTAKYGDLRRRLVFLVLALLVYRIGAHIPVPGIDPDQLAQLFQRQSGGILGMFNL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEHHH
FSGGALSRFTVFALGIMPYISASIIMQLLTIVLPQLESLKKEGQAGQRKITQYTRYGTVI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LATFQALGIAVALEAQPGLVLDPGLMFRATAVITLVTGTMFLMWLGEQITERGLGNGISI
HHHHHHHCEEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
IIFGGIAAGLPNAIGGLFELVRTGSMGIFSAILVVAIIGAVTFVVVFIERGQRKILVNYA
EEECCHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
KRQVGNKIYGGQSSHLPLKLNMAGVIPPIFASSIILFPATIAGWFTAGNSTNPVARVVKD
HHHHCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LAATLSPGQPVYILLYAAAIIFFCFFYTALVYNSREVADNLKKSGAFIPGIRPGEQTTRY
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHH
IDKILVRLTLAGAIYITLVCLLPEFLVLRWNVPFYFGGTSLLIIVVVTMDFMAQVQSYVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEECCHHHHHHHHHHHHHHHHHHHHHH
SQQYESLMKKANFKGNLTLR
HHHHHHHHHHCCCCCCCEEC
>Mature Secondary Structure 
AQAKNTAKYGDLRRRLVFLVLALLVYRIGAHIPVPGIDPDQLAQLFQRQSGGILGMFNL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEHHH
FSGGALSRFTVFALGIMPYISASIIMQLLTIVLPQLESLKKEGQAGQRKITQYTRYGTVI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LATFQALGIAVALEAQPGLVLDPGLMFRATAVITLVTGTMFLMWLGEQITERGLGNGISI
HHHHHHHCEEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
IIFGGIAAGLPNAIGGLFELVRTGSMGIFSAILVVAIIGAVTFVVVFIERGQRKILVNYA
EEECCHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
KRQVGNKIYGGQSSHLPLKLNMAGVIPPIFASSIILFPATIAGWFTAGNSTNPVARVVKD
HHHHCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LAATLSPGQPVYILLYAAAIIFFCFFYTALVYNSREVADNLKKSGAFIPGIRPGEQTTRY
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHH
IDKILVRLTLAGAIYITLVCLLPEFLVLRWNVPFYFGGTSLLIIVVVTMDFMAQVQSYVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEECCHHHHHHHHHHHHHHHHHHHHHH
SQQYESLMKKANFKGNLTLR
HHHHHHHHHHCCCCCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9322765; 10952301 [H]