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The map label for this gene is argJ [H]

Identifier: 187930146

GI number: 187930146

Start: 3211580

End: 3212809

Strand: Reverse

Name: argJ [H]

Synonym: Rpic_3078

Alternate gene names: 187930146

Gene position: 3212809-3211580 (Counterclockwise)

Preceding gene: 187930147

Following gene: 187930145

Centisome position: 81.49

GC content: 66.91

Gene sequence:

>1230_bases
ATGGCTGTGAATCTCGTCGCGCCCGCCGCTGATACCCTGTTGCCGATCGACGGCGTGGACCTCGGCTGGGCCGAGGCCGG
TGTGCGCAAGGCCAATCGCAAGGACGTGCTGCTGGTTCGTATCGCCGAGGGCTCGACGGTAGCCGGTGTGTTTACGCAGA
ACCGTTTCTGCGCGGCGCCTGTGCAGGTATGCCGTGAGCATCTGGCGAGCGGCAAGGGCGCACGCGCGATCGTCGTCAAC
ACGGGTAACGCGAATGCCGGTACGGGCGCGTCTGGCCTTGCGCATGCGCGTCAGACCTGCGATGCCGTGGCCAAGCTGCT
GGGCGTGTCGGCGGAACAGGTGCTGCCGTTCTCGACGGGCGTGATTCTGGAGCCGCTGCCGGTCGACCGCATCATCGCCG
GACTGCCCGCTGCTGAGGCGAACGCCAAGCCGGACAACTGGCTGGCTGCCGCCGAGGCGATTATGACCACCGACACCGTA
CCCAAGGCAGCGTCGGCCACGTGCACGCTGTCGGGCAAAACCGTGCGCATGTCCGGCATCAGCAAGGGTGCAGGCATGAT
CCGTCCGAACATGGCGACGATGCTCGGCTTCATCGCCACCGATGCCGATGTGGATGAAGCCGTGCTTCAAGGTCTGGTGC
GCCACGCCGCCGATCACTCGTTCAACAGCGTGACGGTGGACGGCGATACCTCCACCAACGACTCGTTCGTCGTCATCGCG
ACGGGCCGGGCTGGCACGCCGCGCATCGATTCCGAGTCGCACCCCGACTACGCTGCGCTGCGCGATGCGCTGACGGGCCT
CGCACAAGAGCTGGCGCAGAAGATCGTGCGCGATGGCGAGGGCGCGACCAAGTTCATGGCCATCCAGGTTGAGGGCGGCC
GCAACGTCGAAGAGTGCCGCCTCATCGCCTATGCGGTCGCGCACTCGCCGCTGGTCAAGACCGCGTTCTACGCTTCGGAC
CCCAACCTGGGGCGCATCCTGGCCGCTGTGGGCTACGCCGGCGTGACGGACCTCGACGTGAACGGCGTCAACCTGTGGCT
CGACGACGTGTGGGTCGCGCGAGACGGCGGCCGCAACCCCGAGTACCGCGAAGAAGACGGCCAGCGCGTGATGAAGCAGG
CGGAGATTACCGTGCGCATCGCGCTCGGCCGCGGCGACGCCACCGCCACCGTGTGGACGTGCGACTTCTCGCACGACTAC
GTGTCGATCAACGCCGACTACCGTTCGTGA

Upstream 100 bases:

>100_bases
AGCAGTGCCACGGCAAACTTGTCTGACGCTGCTGGAACCTGTTTTCTGTTGATTCACGATGCCCGCAATGCGGGCATCCT
CATTTTGAAAGGTGTGCTCC

Downstream 100 bases:

>100_bases
TCCGGAGCGCGCCGCTATGTCGTCCGACCTTTCCGCACGGCTCGACCGCTTTCTCGGGCGGCTTGAGCAATGGCTGCCGC
CTGAACTGACCGAAGCTGAC

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS [H]

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MAVNLVAPAADTLLPIDGVDLGWAEAGVRKANRKDVLLVRIAEGSTVAGVFTQNRFCAAPVQVCREHLASGKGARAIVVN
TGNANAGTGASGLAHARQTCDAVAKLLGVSAEQVLPFSTGVILEPLPVDRIIAGLPAAEANAKPDNWLAAAEAIMTTDTV
PKAASATCTLSGKTVRMSGISKGAGMIRPNMATMLGFIATDADVDEAVLQGLVRHAADHSFNSVTVDGDTSTNDSFVVIA
TGRAGTPRIDSESHPDYAALRDALTGLAQELAQKIVRDGEGATKFMAIQVEGGRNVEECRLIAYAVAHSPLVKTAFYASD
PNLGRILAAVGYAGVTDLDVNGVNLWLDDVWVARDGGRNPEYREEDGQRVMKQAEITVRIALGRGDATATVWTCDFSHDY
VSINADYRS

Sequences:

>Translated_409_residues
MAVNLVAPAADTLLPIDGVDLGWAEAGVRKANRKDVLLVRIAEGSTVAGVFTQNRFCAAPVQVCREHLASGKGARAIVVN
TGNANAGTGASGLAHARQTCDAVAKLLGVSAEQVLPFSTGVILEPLPVDRIIAGLPAAEANAKPDNWLAAAEAIMTTDTV
PKAASATCTLSGKTVRMSGISKGAGMIRPNMATMLGFIATDADVDEAVLQGLVRHAADHSFNSVTVDGDTSTNDSFVVIA
TGRAGTPRIDSESHPDYAALRDALTGLAQELAQKIVRDGEGATKFMAIQVEGGRNVEECRLIAYAVAHSPLVKTAFYASD
PNLGRILAAVGYAGVTDLDVNGVNLWLDDVWVARDGGRNPEYREEDGQRVMKQAEITVRIALGRGDATATVWTCDFSHDY
VSINADYRS
>Mature_408_residues
AVNLVAPAADTLLPIDGVDLGWAEAGVRKANRKDVLLVRIAEGSTVAGVFTQNRFCAAPVQVCREHLASGKGARAIVVNT
GNANAGTGASGLAHARQTCDAVAKLLGVSAEQVLPFSTGVILEPLPVDRIIAGLPAAEANAKPDNWLAAAEAIMTTDTVP
KAASATCTLSGKTVRMSGISKGAGMIRPNMATMLGFIATDADVDEAVLQGLVRHAADHSFNSVTVDGDTSTNDSFVVIAT
GRAGTPRIDSESHPDYAALRDALTGLAQELAQKIVRDGEGATKFMAIQVEGGRNVEECRLIAYAVAHSPLVKTAFYASDP
NLGRILAAVGYAGVTDLDVNGVNLWLDDVWVARDGGRNPEYREEDGQRVMKQAEITVRIALGRGDATATVWTCDFSHDYV
SINADYRS

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate [H]

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=413, Percent_Identity=39.9515738498789, Blast_Score=280, Evalue=3e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002813
- InterPro:   IPR016117 [H]

Pfam domain/function: PF01960 ArgJ [H]

EC number: =2.3.1.35; =2.3.1.1 [H]

Molecular weight: Translated: 42897; Mature: 42766

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVNLVAPAADTLLPIDGVDLGWAEAGVRKANRKDVLLVRIAEGSTVAGVFTQNRFCAAP
CEEEEECCCCCCEEECCCCCCCHHHHHHHCCCCCCEEEEEEECCCEEEEEEECCCEEHHH
VQVCREHLASGKGARAIVVNTGNANAGTGASGLAHARQTCDAVAKLLGVSAEQVLPFSTG
HHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCC
VILEPLPVDRIIAGLPAAEANAKPDNWLAAAEAIMTTDTVPKAASATCTLSGKTVRMSGI
CEECCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCEEEECCC
SKGAGMIRPNMATMLGFIATDADVDEAVLQGLVRHAADHSFNSVTVDGDTSTNDSFVVIA
CCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEE
TGRAGTPRIDSESHPDYAALRDALTGLAQELAQKIVRDGEGATKFMAIQVEGGRNVEECR
ECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHH
LIAYAVAHSPLVKTAFYASDPNLGRILAAVGYAGVTDLDVNGVNLWLDDVWVARDGGRNP
HHHHHHHCCCHHHEEEECCCCCHHHHHHHHCCCCCEEECCCCEEEEEEEEEEECCCCCCC
EYREEDGQRVMKQAEITVRIALGRGDATATVWTCDFSHDYVSINADYRS
CCCHHHHHHHHHHCEEEEEEEECCCCCEEEEEEEECCCCEEEEECCCCC
>Mature Secondary Structure 
AVNLVAPAADTLLPIDGVDLGWAEAGVRKANRKDVLLVRIAEGSTVAGVFTQNRFCAAP
EEEEECCCCCCEEECCCCCCCHHHHHHHCCCCCCEEEEEEECCCEEEEEEECCCEEHHH
VQVCREHLASGKGARAIVVNTGNANAGTGASGLAHARQTCDAVAKLLGVSAEQVLPFSTG
HHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCC
VILEPLPVDRIIAGLPAAEANAKPDNWLAAAEAIMTTDTVPKAASATCTLSGKTVRMSGI
CEECCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCEEEECCC
SKGAGMIRPNMATMLGFIATDADVDEAVLQGLVRHAADHSFNSVTVDGDTSTNDSFVVIA
CCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEE
TGRAGTPRIDSESHPDYAALRDALTGLAQELAQKIVRDGEGATKFMAIQVEGGRNVEECR
ECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHH
LIAYAVAHSPLVKTAFYASDPNLGRILAAVGYAGVTDLDVNGVNLWLDDVWVARDGGRNP
HHHHHHHCCCHHHEEEECCCCCHHHHHHHHCCCCCEEECCCCEEEEEEEEEEECCCCCCC
EYREEDGQRVMKQAEITVRIALGRGDATATVWTCDFSHDYVSINADYRS
CCCHHHHHHHHHHCEEEEEEEECCCCCEEEEEEEECCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]