Click here to switch to the map view.

The map label for this gene is cusB [H]

Identifier: 187930013

GI number: 187930013

Start: 3063879

End: 3065033

Strand: Reverse

Name: cusB [H]

Synonym: Rpic_2945

Alternate gene names: 187930013

Gene position: 3065033-3063879 (Counterclockwise)

Preceding gene: 187930015

Following gene: 187930012

Centisome position: 77.74

GC content: 63.55

Gene sequence:

>1155_bases
ATGTGGGGAATCTGGGGGCAAAAGCGCTCGGAAGCTGCGCCCACACCATCGTATGCAGCCGCGCCGGTCACCGTGCCAGC
GCCACCCTCACGCGATGGGCAGGCCGTGACCTTGAGCCAGGGCCAATTGCAGTACATCAAGGTTGCGCCCGTAGAGTTGC
GCGAATTCGCCAACCGGCGCGAGGCGGTGGGCAATATCGACTTCAACGAGGACCGCGCTGTGCAGGTCTTCACGTCGTAC
CAAGGCAAGATCCGCAACACCTACGCCAAGGTGGGCGACATCGTTGCCAAGGGCAAGCCGCTGTTCGATATCGACAGCCC
TGATCTGGTGCAAGCGGAATCCACGCTGATTTCCACTGCTGGTACGCGCAAGTTGACGACTGATGCGCTCGCTCGTGCGC
GCCAGTTGTATGAGATCCAGGGCCTGGCACAGAAGGATCTGGACCAGGCTATCTCCGACCAGCAAGCCGCCGAGGCGGCC
TACAAGGCCGCGCGTGAAGCCCTGGCTGTGTTCGGCAAGACGCCCGCACAGATGGACCAGATCGTGCAGACGCGCAAGAC
TGATTCGCTGCTGACGGTGGTGAGCCCGATCTCGGGCCAGGTGACCGCGCGCAGCGCGCAGCCAGGCTTGCTCTTGCAGC
CCGGCAACGGTACGGCGCCATTCACGGTGGCTGATGTGTCCACCATGTGGATGCAGGCGTTCGTGCCGGAAGCCGATGCA
CCGCTGCTGCACGTCGGCCAGCCGGTCAAGATTCACGTCATGGCGTTCCCAAGCCGGGTCTTCAACGGCAAGATCACCAC
CGTGGGTGCATCGGTCGACGCCAACACGCACCGCATCCTGGTGCGTTCGGAAATCGACGACCCGAAGCACGAACTGCGCC
CCGGCATGTTCACTTCATTCGACATCACCACCGGCGCGCCCATCCAATCCCCAGCGTTGGCGATGGACGGCGTGGTCCGC
GAAGGCGACGGCACCATGACCGCGTGGGTTACGACCGACCGCAAGCGCTTTGCGCGGCGCGTGATCAAGCTTGGCCTGGA
GCAGGATGGCTTTGTGCAGGTGCTCGAAGGCCTGAACGCAGGCGAGCTGGCCGCCAACGAAGGGGCACTGTATCTGAGCA
CGGCTGCCTCCGGCAGCGTCAATAGCGCTAATTGA

Upstream 100 bases:

>100_bases
TGCGGGCAAAATTTCTATCAACTGGGGTACTGCTGTGCAGGTTGATTACAAGTCCGCAGCCATTGGGGGCGTTGTCGCCG
GGTTGGTCGTTGGCGGCCTG

Downstream 100 bases:

>100_bases
GGGGAGTTCACCGTGCTCAAAGCGATTCTGAAGCTGTCGCTGCTGCGACGGCCGCTGATCCTGTTGTTCCTGCTGGCGTT
CGTGACGGCAGGGCTGTTCG

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MWGIWGQKRSEAAPTPSYAAAPVTVPAPPSRDGQAVTLSQGQLQYIKVAPVELREFANRREAVGNIDFNEDRAVQVFTSY
QGKIRNTYAKVGDIVAKGKPLFDIDSPDLVQAESTLISTAGTRKLTTDALARARQLYEIQGLAQKDLDQAISDQQAAEAA
YKAAREALAVFGKTPAQMDQIVQTRKTDSLLTVVSPISGQVTARSAQPGLLLQPGNGTAPFTVADVSTMWMQAFVPEADA
PLLHVGQPVKIHVMAFPSRVFNGKITTVGASVDANTHRILVRSEIDDPKHELRPGMFTSFDITTGAPIQSPALAMDGVVR
EGDGTMTAWVTTDRKRFARRVIKLGLEQDGFVQVLEGLNAGELAANEGALYLSTAASGSVNSAN

Sequences:

>Translated_384_residues
MWGIWGQKRSEAAPTPSYAAAPVTVPAPPSRDGQAVTLSQGQLQYIKVAPVELREFANRREAVGNIDFNEDRAVQVFTSY
QGKIRNTYAKVGDIVAKGKPLFDIDSPDLVQAESTLISTAGTRKLTTDALARARQLYEIQGLAQKDLDQAISDQQAAEAA
YKAAREALAVFGKTPAQMDQIVQTRKTDSLLTVVSPISGQVTARSAQPGLLLQPGNGTAPFTVADVSTMWMQAFVPEADA
PLLHVGQPVKIHVMAFPSRVFNGKITTVGASVDANTHRILVRSEIDDPKHELRPGMFTSFDITTGAPIQSPALAMDGVVR
EGDGTMTAWVTTDRKRFARRVIKLGLEQDGFVQVLEGLNAGELAANEGALYLSTAASGSVNSAN
>Mature_384_residues
MWGIWGQKRSEAAPTPSYAAAPVTVPAPPSRDGQAVTLSQGQLQYIKVAPVELREFANRREAVGNIDFNEDRAVQVFTSY
QGKIRNTYAKVGDIVAKGKPLFDIDSPDLVQAESTLISTAGTRKLTTDALARARQLYEIQGLAQKDLDQAISDQQAAEAA
YKAAREALAVFGKTPAQMDQIVQTRKTDSLLTVVSPISGQVTARSAQPGLLLQPGNGTAPFTVADVSTMWMQAFVPEADA
PLLHVGQPVKIHVMAFPSRVFNGKITTVGASVDANTHRILVRSEIDDPKHELRPGMFTSFDITTGAPIQSPALAMDGVVR
EGDGTMTAWVTTDRKRFARRVIKLGLEQDGFVQVLEGLNAGELAANEGALYLSTAASGSVNSAN

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=320, Percent_Identity=25.3125, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 41145; Mature: 41145

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWGIWGQKRSEAAPTPSYAAAPVTVPAPPSRDGQAVTLSQGQLQYIKVAPVELREFANRR
CCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCEEEECCCCEEEEEECCHHHHHHHHHH
EAVGNIDFNEDRAVQVFTSYQGKIRNTYAKVGDIVAKGKPLFDIDSPDLVQAESTLISTA
HHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHCCC
GTRKLTTDALARARQLYEIQGLAQKDLDQAISDQQAAEAAYKAAREALAVFGKTPAQMDQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
IVQTRKTDSLLTVVSPISGQVTARSAQPGLLLQPGNGTAPFTVADVSTMWMQAFVPEADA
HHHHHCCCCEEEEECCCCCCEEEECCCCCEEEECCCCCCCEEEHHHHHHHHHHHCCCCCC
PLLHVGQPVKIHVMAFPSRVFNGKITTVGASVDANTHRILVRSEIDDPKHELRPGMFTSF
CEEECCCCEEEEEEEECHHHHCCEEEEEECEECCCCEEEEEECCCCCCHHHCCCCCEEEE
DITTGAPIQSPALAMDGVVREGDGTMTAWVTTDRKRFARRVIKLGLEQDGFVQVLEGLNA
ECCCCCCCCCCCHHHCCEEECCCCCEEEEEECHHHHHHHHHHHHCCCCCCHHHHHHCCCC
GELAANEGALYLSTAASGSVNSAN
CCEECCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MWGIWGQKRSEAAPTPSYAAAPVTVPAPPSRDGQAVTLSQGQLQYIKVAPVELREFANRR
CCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCEEEECCCCEEEEEECCHHHHHHHHHH
EAVGNIDFNEDRAVQVFTSYQGKIRNTYAKVGDIVAKGKPLFDIDSPDLVQAESTLISTA
HHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHCCC
GTRKLTTDALARARQLYEIQGLAQKDLDQAISDQQAAEAAYKAAREALAVFGKTPAQMDQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
IVQTRKTDSLLTVVSPISGQVTARSAQPGLLLQPGNGTAPFTVADVSTMWMQAFVPEADA
HHHHHCCCCEEEEECCCCCCEEEECCCCCEEEECCCCCCCEEEHHHHHHHHHHHCCCCCC
PLLHVGQPVKIHVMAFPSRVFNGKITTVGASVDANTHRILVRSEIDDPKHELRPGMFTSF
CEEECCCCEEEEEEEECHHHHCCEEEEEECEECCCCEEEEEECCCCCCHHHCCCCCEEEE
DITTGAPIQSPALAMDGVVREGDGTMTAWVTTDRKRFARRVIKLGLEQDGFVQVLEGLNA
ECCCCCCCCCCCHHHCCEEECCCCCEEEEEECHHHHHHHHHHHHCCCCCCHHHHHHCCCC
GELAANEGALYLSTAASGSVNSAN
CCEECCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]