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The map label for this gene is senX3 [H]

Identifier: 187930010

GI number: 187930010

Start: 3058382

End: 3059989

Strand: Reverse

Name: senX3 [H]

Synonym: Rpic_2942

Alternate gene names: 187930010

Gene position: 3059989-3058382 (Counterclockwise)

Preceding gene: 187930012

Following gene: 187930005

Centisome position: 77.61

GC content: 60.57

Gene sequence:

>1608_bases
ATGCAATCGCCAAAAACGGTCACAGCCGCGCCAGACGGGCGGCGCTTTGGAATCGCATCGCCGTTGATCCTGCGTCCCAT
CCGGGTCCGGCTGACGCTGGTGTTCGTGATCTTTTTACTGCTGGTGGTCGGCGTCGGCGCTTTCAGTATCGACCAACTGG
CGAGCTTCCACAGCGTATCTGCGCAGATCAGCGGGCGCTGGCTACAGAACAGCCGGATTCTGGGCGACCTCAACAACTAC
ATCTCGGATTATCGCGCGGCCGAAGGCGATTTTCTGATCGCCTCATCACGCGCTGACCTGCGAGCCGCCGACGAACAGGT
CGCCATGCTCGACAAAGCGATTGCCACGTCCCAGGCCCGCTACGACAAGATCGAACACGACAGCGCCGAGCACGAGCTTT
ACAGCCAGTTTGTCACCCAATGGAACACGTATCGCGAGCTTGCGCGACGGCTGATGATTTCTGCCAAGGCAGGCGACGTA
GCGGGTGCTGCGCGGCTCTATCACGCGGATTCCAAACACGCATTCGACTTGGCCAACGACACCTTGGGCGTGATGACCGA
ACGCAGTGTCGCTGGCGCCACGGCAGAAACCGAGCGAGAGGCGCAGGCCTACCACGATGCGCGGCAACTCATCGTTGGGG
CGATCGTTGTGGCGGCATGTCTGGTCGTGCTGGCCGTGATCTACCTTGTCTTTGCCGTGTCGCGCCCGATTGCCGTGCTA
GTGGATCGCATGCACCGCGTTGCCAACAACGATACCCAGATCGACATCCCAGGCTTGGACCGCCACGACGAGATTGGCGA
CATCGCGCAAGCCGTGGCGCGTTTTCGAGAAAACACAATCGAACTGGGGCGCAGCAAAGATGTACTGACCGCCCAGGCGG
CCGTATTGCAGGAGACGCTTGACAAAGAGCGCCGCATGGCCGAACTCCAACGCAATTTCATCTCAATGGCGTCGCATGAA
TTCCGTACGCCACTGGGCGTGATTGACGGCCAGGCCCAGCGGTTGATACGCACGCGTGATGCGTTGCAGCCCGAGGCGCT
CGAAGAACGCTGCGGGAAAATCCGGGCGGCCGTGCAGCGCATGACGCACCTGATGGATCACTTGCTCGACTCTTCGCAGT
GGCTGGATTCCACGACGCCAGCAGCGATGCGGCGCACCGATTTCCCGCTTGCAGCGCTTCTGCACGAGGTTTGCGAAATG
CACTTGGAAGGCACGCCGAGCGCTCGGATCGAGGTGTGCATAGAGACGGATGAGCCGAACACATTCTTCGGCGATGCCCG
GCTCTTATTCCAGGCCTTCAGCAATCTTGTCGGCAACGCCGTTAAGTATTCGCCGCCAGGCGCACCGGTCAGTGTGCGTA
TGCGCAGCGATGCCGACGGTGTGTCGGTAACTGTGGAAGACCGGGGCCTGGGCATACCAGAGCGCGATATCGAGCGCTTG
TTCGAGCGCTACGTGCGCGGCGGCAACGTTGCAGGGACGGTTGGAGCAGGTGTCGGGCTTTACTTGGTGAAGCTGGTCGT
GGAACTGCACCGAGGAACGATCACTGTGACCAGCGAAGAAGGCAAAGGCTCAAGATTCAACGTGTTCTTACCGCGACTGA
ACGGCTAG

Upstream 100 bases:

>100_bases
ATCTTGGGGTTGGCTGGCTTCATGGGGATTTCAGCTGGTGGTATGGTGACTGATGCTCCGCTCATGACGTCGTCAAGAAA
AACTGCGCAGGACATTACCT

Downstream 100 bases:

>100_bases
CTTGTACCGGCTGTGAGCCTGTCTACGGGATCGACGTGGGTCATGACATTGAGAACATCATGTCTTTCCATGACGCGTCG
CCTTGCTTCCAGCGCGATGT

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 535; Mature: 535

Protein sequence:

>535_residues
MQSPKTVTAAPDGRRFGIASPLILRPIRVRLTLVFVIFLLLVVGVGAFSIDQLASFHSVSAQISGRWLQNSRILGDLNNY
ISDYRAAEGDFLIASSRADLRAADEQVAMLDKAIATSQARYDKIEHDSAEHELYSQFVTQWNTYRELARRLMISAKAGDV
AGAARLYHADSKHAFDLANDTLGVMTERSVAGATAETEREAQAYHDARQLIVGAIVVAACLVVLAVIYLVFAVSRPIAVL
VDRMHRVANNDTQIDIPGLDRHDEIGDIAQAVARFRENTIELGRSKDVLTAQAAVLQETLDKERRMAELQRNFISMASHE
FRTPLGVIDGQAQRLIRTRDALQPEALEERCGKIRAAVQRMTHLMDHLLDSSQWLDSTTPAAMRRTDFPLAALLHEVCEM
HLEGTPSARIEVCIETDEPNTFFGDARLLFQAFSNLVGNAVKYSPPGAPVSVRMRSDADGVSVTVEDRGLGIPERDIERL
FERYVRGGNVAGTVGAGVGLYLVKLVVELHRGTITVTSEEGKGSRFNVFLPRLNG

Sequences:

>Translated_535_residues
MQSPKTVTAAPDGRRFGIASPLILRPIRVRLTLVFVIFLLLVVGVGAFSIDQLASFHSVSAQISGRWLQNSRILGDLNNY
ISDYRAAEGDFLIASSRADLRAADEQVAMLDKAIATSQARYDKIEHDSAEHELYSQFVTQWNTYRELARRLMISAKAGDV
AGAARLYHADSKHAFDLANDTLGVMTERSVAGATAETEREAQAYHDARQLIVGAIVVAACLVVLAVIYLVFAVSRPIAVL
VDRMHRVANNDTQIDIPGLDRHDEIGDIAQAVARFRENTIELGRSKDVLTAQAAVLQETLDKERRMAELQRNFISMASHE
FRTPLGVIDGQAQRLIRTRDALQPEALEERCGKIRAAVQRMTHLMDHLLDSSQWLDSTTPAAMRRTDFPLAALLHEVCEM
HLEGTPSARIEVCIETDEPNTFFGDARLLFQAFSNLVGNAVKYSPPGAPVSVRMRSDADGVSVTVEDRGLGIPERDIERL
FERYVRGGNVAGTVGAGVGLYLVKLVVELHRGTITVTSEEGKGSRFNVFLPRLNG
>Mature_535_residues
MQSPKTVTAAPDGRRFGIASPLILRPIRVRLTLVFVIFLLLVVGVGAFSIDQLASFHSVSAQISGRWLQNSRILGDLNNY
ISDYRAAEGDFLIASSRADLRAADEQVAMLDKAIATSQARYDKIEHDSAEHELYSQFVTQWNTYRELARRLMISAKAGDV
AGAARLYHADSKHAFDLANDTLGVMTERSVAGATAETEREAQAYHDARQLIVGAIVVAACLVVLAVIYLVFAVSRPIAVL
VDRMHRVANNDTQIDIPGLDRHDEIGDIAQAVARFRENTIELGRSKDVLTAQAAVLQETLDKERRMAELQRNFISMASHE
FRTPLGVIDGQAQRLIRTRDALQPEALEERCGKIRAAVQRMTHLMDHLLDSSQWLDSTTPAAMRRTDFPLAALLHEVCEM
HLEGTPSARIEVCIETDEPNTFFGDARLLFQAFSNLVGNAVKYSPPGAPVSVRMRSDADGVSVTVEDRGLGIPERDIERL
FERYVRGGNVAGTVGAGVGLYLVKLVVELHRGTITVTSEEGKGSRFNVFLPRLNG

Specific function: Probably forms part of a two-component regulatory system senX3/regX3. Phosphorylates regX3 (Probable) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=224, Percent_Identity=32.1428571428571, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87081816, Length=340, Percent_Identity=27.6470588235294, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI145693157, Length=243, Percent_Identity=27.9835390946502, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788393, Length=298, Percent_Identity=26.1744966442953, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1789149, Length=345, Percent_Identity=25.5072463768116, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1786912, Length=256, Percent_Identity=26.953125, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI48994928, Length=230, Percent_Identity=30.4347826086957, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790861, Length=321, Percent_Identity=25.5451713395639, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1786783, Length=332, Percent_Identity=25.9036144578313, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788279, Length=224, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790551, Length=327, Percent_Identity=24.7706422018349, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790436, Length=239, Percent_Identity=26.7782426778243, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788713, Length=257, Percent_Identity=22.9571984435798, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788549, Length=239, Percent_Identity=25.9414225941423, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789403, Length=217, Percent_Identity=29.0322580645161, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 58956; Mature: 58956

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSPKTVTAAPDGRRFGIASPLILRPIRVRLTLVFVIFLLLVVGVGAFSIDQLASFHSVS
CCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
AQISGRWLQNSRILGDLNNYISDYRAAEGDFLIASSRADLRAADEQVAMLDKAIATSQAR
HHHCCCHHCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
YDKIEHDSAEHELYSQFVTQWNTYRELARRLMISAKAGDVAGAARLYHADSKHAFDLAND
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHCCC
TLGVMTERSVAGATAETEREAQAYHDARQLIVGAIVVAACLVVLAVIYLVFAVSRPIAVL
CHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VDRMHRVANNDTQIDIPGLDRHDEIGDIAQAVARFRENTIELGRSKDVLTAQAAVLQETL
HHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
DKERRMAELQRNFISMASHEFRTPLGVIDGQAQRLIRTRDALQPEALEERCGKIRAAVQR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
MTHLMDHLLDSSQWLDSTTPAAMRRTDFPLAALLHEVCEMHLEGTPSARIEVCIETDEPN
HHHHHHHHHCCHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCC
TFFGDARLLFQAFSNLVGNAVKYSPPGAPVSVRMRSDADGVSVTVEDRGLGIPERDIERL
CCHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHH
FERYVRGGNVAGTVGAGVGLYLVKLVVELHRGTITVTSEEGKGSRFNVFLPRLNG
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEEECCCCC
>Mature Secondary Structure
MQSPKTVTAAPDGRRFGIASPLILRPIRVRLTLVFVIFLLLVVGVGAFSIDQLASFHSVS
CCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
AQISGRWLQNSRILGDLNNYISDYRAAEGDFLIASSRADLRAADEQVAMLDKAIATSQAR
HHHCCCHHCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
YDKIEHDSAEHELYSQFVTQWNTYRELARRLMISAKAGDVAGAARLYHADSKHAFDLAND
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHCCC
TLGVMTERSVAGATAETEREAQAYHDARQLIVGAIVVAACLVVLAVIYLVFAVSRPIAVL
CHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VDRMHRVANNDTQIDIPGLDRHDEIGDIAQAVARFRENTIELGRSKDVLTAQAAVLQETL
HHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
DKERRMAELQRNFISMASHEFRTPLGVIDGQAQRLIRTRDALQPEALEERCGKIRAAVQR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
MTHLMDHLLDSSQWLDSTTPAAMRRTDFPLAALLHEVCEMHLEGTPSARIEVCIETDEPN
HHHHHHHHHCCHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCC
TFFGDARLLFQAFSNLVGNAVKYSPPGAPVSVRMRSDADGVSVTVEDRGLGIPERDIERL
CCHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHH
FERYVRGGNVAGTVGAGVGLYLVKLVVELHRGTITVTSEEGKGSRFNVFLPRLNG
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9426136; 12788972 [H]