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The map label for this gene is hrcA [H]

Identifier: 187929954

GI number: 187929954

Start: 2991474

End: 2992532

Strand: Reverse

Name: hrcA [H]

Synonym: Rpic_2886

Alternate gene names: 187929954

Gene position: 2992532-2991474 (Counterclockwise)

Preceding gene: 187929960

Following gene: 187929953

Centisome position: 75.9

GC content: 63.27

Gene sequence:

>1059_bases
ATGGACAAGCGCGCCACCATCCTCCTCAAGACCCTGATCGAACGGTATATCGCCGAGGGGCAGCCCGTGGGCTCCCGCAC
CTTGTCGAAATATTCGGGGCTCGATCTGTCGCCGGCCACCATCCGTAATGTGATGTCTGACCTGGAAGAGATGGGCTTCA
TTGCCAGCCCACACACCTCGGCCGGGCGCGTGCCGACGCCGCGCGGCTACCGCCTCTTTGTCGATACCATGCTGACGGCC
AGCCCGCTGGATGTGCTGAGCACGCAGGATCGCATGGCGCAGCAGATGGTGGGCGCGATCGCAGAGCAGGTGCGCTCGCA
ACTTGCGTCGCATGGGGCGGAATCGTCGCAGCGGGTAATTGCGGCGGCGGCGCAAACCTTGTCCAACCTCTCGCAGTTTG
CCGGCATCGTGATGACGCCGCGGCGCACGCACGCGTTCCGGCAGATCGAATTCCTGCGGCTGTCGGAATCGCGCATCCTG
CTGATCGTCGTCACGCCCGAGGGCGACGTGCAGAACCGCATTATCCATACCGATACGCCTTACAGCCCGTCGCAACTGGT
GGAAGCGGCCAACTACATCAACGCGCATTACGGTGGCCAGACGTTCGATGCAGTGCGCGAAAGCCTGCGGGGTGAACTCT
CTGCGCTGCAGGCCGACATGACGGCACTGATGCAGGCGGCCGTGGAGGCGGGCAGCAGTGCCGTGTCGGACGAGGAGCCG
GTCGTCATCTCGGGCGAGCGCAAGCTGCTGGATGTGGAAGACCTGTCTTCGTCCATGGACAAGCTGCGCCGGCTCTTTGC
CGTGTTCGAGCAGAAGACTGGCCTGCTGCAATTGCTCGACGTATCCAGCCGCGCCGAGGGCGTGCAGATCTTCATCGGCG
GCGAAAGCAGCCTCGTCCCGCACGAAGACATGGCGGTCATCACCGCACCGTATGAGGTGGACGGCAAGATCGTCGGCACG
CTCGGCGTGATCGGGCCGATGCGCATGGCATATGAGCGCGTGATCCCAATTGTAGATATCACGGCCAAGCTGCTGTCCAG
CACGCTCAGCCAATATTGA

Upstream 100 bases:

>100_bases
ACCATATCGATATGACCGTCGCCACGTTAGCGCGTGTTTCGTGGAGAAACGCCGACATCACCCGCAGGCGGGCGCCGATT
TTGCGTAAAATTGACGAATC

Downstream 100 bases:

>100_bases
TCTACCGGTTGTTCTGTCTGCGAGCCGCATAAGCTCAGCCGATTTTCTTCGACGACAGGCTACGCTGCCGTCTCTCACAA
TCGACTCCGGCGCATGTGCG

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MDKRATILLKTLIERYIAEGQPVGSRTLSKYSGLDLSPATIRNVMSDLEEMGFIASPHTSAGRVPTPRGYRLFVDTMLTA
SPLDVLSTQDRMAQQMVGAIAEQVRSQLASHGAESSQRVIAAAAQTLSNLSQFAGIVMTPRRTHAFRQIEFLRLSESRIL
LIVVTPEGDVQNRIIHTDTPYSPSQLVEAANYINAHYGGQTFDAVRESLRGELSALQADMTALMQAAVEAGSSAVSDEEP
VVISGERKLLDVEDLSSSMDKLRRLFAVFEQKTGLLQLLDVSSRAEGVQIFIGGESSLVPHEDMAVITAPYEVDGKIVGT
LGVIGPMRMAYERVIPIVDITAKLLSSTLSQY

Sequences:

>Translated_352_residues
MDKRATILLKTLIERYIAEGQPVGSRTLSKYSGLDLSPATIRNVMSDLEEMGFIASPHTSAGRVPTPRGYRLFVDTMLTA
SPLDVLSTQDRMAQQMVGAIAEQVRSQLASHGAESSQRVIAAAAQTLSNLSQFAGIVMTPRRTHAFRQIEFLRLSESRIL
LIVVTPEGDVQNRIIHTDTPYSPSQLVEAANYINAHYGGQTFDAVRESLRGELSALQADMTALMQAAVEAGSSAVSDEEP
VVISGERKLLDVEDLSSSMDKLRRLFAVFEQKTGLLQLLDVSSRAEGVQIFIGGESSLVPHEDMAVITAPYEVDGKIVGT
LGVIGPMRMAYERVIPIVDITAKLLSSTLSQY
>Mature_352_residues
MDKRATILLKTLIERYIAEGQPVGSRTLSKYSGLDLSPATIRNVMSDLEEMGFIASPHTSAGRVPTPRGYRLFVDTMLTA
SPLDVLSTQDRMAQQMVGAIAEQVRSQLASHGAESSQRVIAAAAQTLSNLSQFAGIVMTPRRTHAFRQIEFLRLSESRIL
LIVVTPEGDVQNRIIHTDTPYSPSQLVEAANYINAHYGGQTFDAVRESLRGELSALQADMTALMQAAVEAGSSAVSDEEP
VVISGERKLLDVEDLSSSMDKLRRLFAVFEQKTGLLQLLDVSSRAEGVQIFIGGESSLVPHEDMAVITAPYEVDGKIVGT
LGVIGPMRMAYERVIPIVDITAKLLSSTLSQY

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005104
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03444 DUF293; PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 38282; Mature: 38282

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKRATILLKTLIERYIAEGQPVGSRTLSKYSGLDLSPATIRNVMSDLEEMGFIASPHTS
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEECCCCC
AGRVPTPRGYRLFVDTMLTASPLDVLSTQDRMAQQMVGAIAEQVRSQLASHGAESSQRVI
CCCCCCCCCCEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AAAAQTLSNLSQFAGIVMTPRRTHAFRQIEFLRLSESRILLIVVTPEGDVQNRIIHTDTP
HHHHHHHHHHHHHHCEEECCHHHHHHHHHHHEEECCCCEEEEEECCCCCCCCCEEECCCC
YSPSQLVEAANYINAHYGGQTFDAVRESLRGELSALQADMTALMQAAVEAGSSAVSDEEP
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VVISGERKLLDVEDLSSSMDKLRRLFAVFEQKTGLLQLLDVSSRAEGVQIFIGGESSLVP
EEEECCCCEECHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCEEEEECCCCCCCC
HEDMAVITAPYEVDGKIVGTLGVIGPMRMAYERVIPIVDITAKLLSSTLSQY
CCCCEEEECCEEECCEEEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDKRATILLKTLIERYIAEGQPVGSRTLSKYSGLDLSPATIRNVMSDLEEMGFIASPHTS
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEECCCCC
AGRVPTPRGYRLFVDTMLTASPLDVLSTQDRMAQQMVGAIAEQVRSQLASHGAESSQRVI
CCCCCCCCCCEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AAAAQTLSNLSQFAGIVMTPRRTHAFRQIEFLRLSESRILLIVVTPEGDVQNRIIHTDTP
HHHHHHHHHHHHHHCEEECCHHHHHHHHHHHEEECCCCEEEEEECCCCCCCCCEEECCCC
YSPSQLVEAANYINAHYGGQTFDAVRESLRGELSALQADMTALMQAAVEAGSSAVSDEEP
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VVISGERKLLDVEDLSSSMDKLRRLFAVFEQKTGLLQLLDVSSRAEGVQIFIGGESSLVP
EEEECCCCEECHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCEEEEECCCCCCCC
HEDMAVITAPYEVDGKIVGTLGVIGPMRMAYERVIPIVDITAKLLSSTLSQY
CCCCEEEECCEEECCEEEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]