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The map label for this gene is hutI [H]

Identifier: 187929946

GI number: 187929946

Start: 2982246

End: 2983481

Strand: Reverse

Name: hutI [H]

Synonym: Rpic_2878

Alternate gene names: 187929946

Gene position: 2983481-2982246 (Counterclockwise)

Preceding gene: 187929947

Following gene: 187929945

Centisome position: 75.67

GC content: 68.69

Gene sequence:

>1236_bases
ATGGCTGATCCGGCCAACCCGCACTGGGACGGGCTCTGGACCAACGTCCATCTCGCCACGCTCGCCGCCGATGCCGACGG
CTACGGCGAGATCCGCGACGGCGCCATCGCCGTCAAGGACGGCCGCATTGCGTGGCTTGGGTACCGCGCTGATGTGCCCG
TCAACGCCCGCGCCACACGCGAACACGATGGCGGCGGCGCGTGGCTCACGCCCGGCCTGATCGACTGCCACACACACCTC
GTCTACGCCGGCAACCGCAGCAATGAATTCGAAGCGCGCCTGAACGGCGTGCCATACGAAGAGATCGCGCGCGCGGGCGG
CGGCATCCTCTCGACCGTTCGCGCCACGCGGGCGGCCAGCGAGGACGCGCTGGCCGAAGCCAGTCTGCCTCGCCTGAATG
CCCTGAGCGCCGAAGGTGTCACGACCGTCGAAATCAAGTCGGGCTACGGCCTGAACCTCGAAACCGAGCGCCGCATGCTG
CGGGTGGCGCGCCGCTTCGGCCAGGCATTGCCAGTGCGCGTGCGGACCACGTTCCTCGGCGCGCATGCCGTACCGCCCGA
ATTTGCCGGCCGCGCGGATGACTACATCGATCATCTGTGCGCCGATGTGCTGCCCGCGCTTGCCGGAGAAGGTCTTGTCG
ATGCGGTTGACGCCTTCTGCGAAACCATTGGTTTTACGCCCGCACAGACAGTGCGCATGTTCGACGCTGCCCAGCGCCAC
GGCCTGCCGGTCAAGCTGCATGCCGAACAGCTCTCCGACCAGGGCGGCGCGGCGCTGGTGGCTCGCTACGGCGGTCTTTC
AGCGGATCATCTCGAATGCCTGACCGATGCAGGCGTTGCCGCCATGGCGCAAGCCGGCACGGTCGCCGTGCTGCTGCCCG
GCGCGTTCTACTGCCTGCGCGAAACGCGCCTGCCGCCGATGGCCGCGCTGCGTGCCGCCAGTGTGCCCATGGCCGTGTCG
ACCGACTGCAACCCTGGCACATCGCCGTTGTCGTCGCTGCTGCTGGCGATGAACATGGCGTGCACGCTGTTCCGCATGAC
GCCGCTGGAAGCGCTGACCGGCGCCACGCGTCATGCTGCCGCCGCGCTGGGCCTGTCTGGCACGTGTGGCGTGCTGGCTC
CGGGCTGCGCGGCCGATTTCGCTCTGTGGCGCATCGACCGGCCCGCCGATCTGGCGTACGCGATGGGGCTTAACCCGTGT
GTTGGTGTGGTCAAGGACGGCGCCGTGGTGGCGTAA

Upstream 100 bases:

>100_bases
GAACTGAACCCGTCGCTCGACATTGATCACCACACGGCACGTGTTGCTGCCCGCCTCGTGGCGCGCGTGGCAGACGGCAT
TGGCCTGCAGGGAGCCGCAC

Downstream 100 bases:

>100_bases
GGAACACGCGATGAATCGGCTCGTATAATCGGCCGGTCTATCGCGAACCCGCGCCCATGCCCTTCTTGCCCGAACCCCTG
TTCCAGCACGGCCAGCCCGA

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase [H]

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MADPANPHWDGLWTNVHLATLAADADGYGEIRDGAIAVKDGRIAWLGYRADVPVNARATREHDGGGAWLTPGLIDCHTHL
VYAGNRSNEFEARLNGVPYEEIARAGGGILSTVRATRAASEDALAEASLPRLNALSAEGVTTVEIKSGYGLNLETERRML
RVARRFGQALPVRVRTTFLGAHAVPPEFAGRADDYIDHLCADVLPALAGEGLVDAVDAFCETIGFTPAQTVRMFDAAQRH
GLPVKLHAEQLSDQGGAALVARYGGLSADHLECLTDAGVAAMAQAGTVAVLLPGAFYCLRETRLPPMAALRAASVPMAVS
TDCNPGTSPLSSLLLAMNMACTLFRMTPLEALTGATRHAAAALGLSGTCGVLAPGCAADFALWRIDRPADLAYAMGLNPC
VGVVKDGAVVA

Sequences:

>Translated_411_residues
MADPANPHWDGLWTNVHLATLAADADGYGEIRDGAIAVKDGRIAWLGYRADVPVNARATREHDGGGAWLTPGLIDCHTHL
VYAGNRSNEFEARLNGVPYEEIARAGGGILSTVRATRAASEDALAEASLPRLNALSAEGVTTVEIKSGYGLNLETERRML
RVARRFGQALPVRVRTTFLGAHAVPPEFAGRADDYIDHLCADVLPALAGEGLVDAVDAFCETIGFTPAQTVRMFDAAQRH
GLPVKLHAEQLSDQGGAALVARYGGLSADHLECLTDAGVAAMAQAGTVAVLLPGAFYCLRETRLPPMAALRAASVPMAVS
TDCNPGTSPLSSLLLAMNMACTLFRMTPLEALTGATRHAAAALGLSGTCGVLAPGCAADFALWRIDRPADLAYAMGLNPC
VGVVKDGAVVA
>Mature_410_residues
ADPANPHWDGLWTNVHLATLAADADGYGEIRDGAIAVKDGRIAWLGYRADVPVNARATREHDGGGAWLTPGLIDCHTHLV
YAGNRSNEFEARLNGVPYEEIARAGGGILSTVRATRAASEDALAEASLPRLNALSAEGVTTVEIKSGYGLNLETERRMLR
VARRFGQALPVRVRTTFLGAHAVPPEFAGRADDYIDHLCADVLPALAGEGLVDAVDAFCETIGFTPAQTVRMFDAAQRHG
LPVKLHAEQLSDQGGAALVARYGGLSADHLECLTDAGVAAMAQAGTVAVLLPGAFYCLRETRLPPMAALRAASVPMAVST
DCNPGTSPLSSLLLAMNMACTLFRMTPLEALTGATRHAAAALGLSGTCGVLAPGCAADFALWRIDRPADLAYAMGLNPCV
GVVKDGAVVA

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family [H]

Homologues:

Organism=Homo sapiens, GI223972677, Length=339, Percent_Identity=38.9380530973451, Blast_Score=191, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17555004, Length=369, Percent_Identity=34.9593495934959, Blast_Score=203, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.7 [H]

Molecular weight: Translated: 42973; Mature: 42842

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADPANPHWDGLWTNVHLATLAADADGYGEIRDGAIAVKDGRIAWLGYRADVPVNARATR
CCCCCCCCCCCEECEEEEEEEEECCCCCCCCCCCEEEEECCEEEEEEEECCCCCCCCCCC
EHDGGGAWLTPGLIDCHTHLVYAGNRSNEFEARLNGVPYEEIARAGGGILSTVRATRAAS
CCCCCCCEECCCCEECEEEEEEECCCCCCHHHHCCCCCHHHHHHCCCCHHHHHHHHHHCC
EDALAEASLPRLNALSAEGVTTVEIKSGYGLNLETERRMLRVARRFGQALPVRVRTTFLG
HHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEC
AHAVPPEFAGRADDYIDHLCADVLPALAGEGLVDAVDAFCETIGFTPAQTVRMFDAAQRH
CCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
GLPVKLHAEQLSDQGGAALVARYGGLSADHLECLTDAGVAAMAQAGTVAVLLPGAFYCLR
CCCEEEEHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHCCCEEEEEECCHHHHHH
ETRLPPMAALRAASVPMAVSTDCNPGTSPLSSLLLAMNMACTLFRMTPLEALTGATRHAA
HCCCCHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHH
AALGLSGTCGVLAPGCAADFALWRIDRPADLAYAMGLNPCVGVVKDGAVVA
HHCCCCCCCCCCCCCHHHHHEEEECCCCCHHHHHCCCCHHHHHHCCCCCCC
>Mature Secondary Structure 
ADPANPHWDGLWTNVHLATLAADADGYGEIRDGAIAVKDGRIAWLGYRADVPVNARATR
CCCCCCCCCCEECEEEEEEEEECCCCCCCCCCCEEEEECCEEEEEEEECCCCCCCCCCC
EHDGGGAWLTPGLIDCHTHLVYAGNRSNEFEARLNGVPYEEIARAGGGILSTVRATRAAS
CCCCCCCEECCCCEECEEEEEEECCCCCCHHHHCCCCCHHHHHHCCCCHHHHHHHHHHCC
EDALAEASLPRLNALSAEGVTTVEIKSGYGLNLETERRMLRVARRFGQALPVRVRTTFLG
HHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEC
AHAVPPEFAGRADDYIDHLCADVLPALAGEGLVDAVDAFCETIGFTPAQTVRMFDAAQRH
CCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
GLPVKLHAEQLSDQGGAALVARYGGLSADHLECLTDAGVAAMAQAGTVAVLLPGAFYCLR
CCCEEEEHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHCCCEEEEEECCHHHHHH
ETRLPPMAALRAASVPMAVSTDCNPGTSPLSSLLLAMNMACTLFRMTPLEALTGATRHAA
HCCCCHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHH
AALGLSGTCGVLAPGCAADFALWRIDRPADLAYAMGLNPCVGVVKDGAVVA
HHCCCCCCCCCCCCCHHHHHEEEECCCCCHHHHHCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]