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The map label for this gene is cobT [H]

Identifier: 187929734

GI number: 187929734

Start: 2776479

End: 2777543

Strand: Reverse

Name: cobT [H]

Synonym: Rpic_2663

Alternate gene names: 187929734

Gene position: 2777543-2776479 (Counterclockwise)

Preceding gene: 187929735

Following gene: 187929733

Centisome position: 70.45

GC content: 68.17

Gene sequence:

>1065_bases
ATGAACCAAACCATGTACATTCCGCCATTTGACGATGCGTTGCGCGTGCGCCTGCAGGCGGCCGTGGACAGCAAGACCAA
GCCGCTCGGCGCGCTGGGCCGGCTTGAATCGCTGGCCGTGCAGATCGGCCTGATCCAGAACACCGACACACCGCAGCTGA
CGCGCCCCGCGATGGTGGTGTTTGCCGCAGACCACGGCATCGCGCACGCAGGCGTGAGCGCGTACCCTCAAGCGGTGACC
GCGCAGATGGTGCTCAATTTCATCGCGGGCGGTGCAGCCGTCAACGTGTTCTGCCGCCAGCATGGGTTTGCGCTGGAGGT
GGTAAACGCCGGTGTCGCCGCACCGTTGTGGGCGGCAGATGCGCCGGGCCTGGTCGATGCACCTGTCGGCCCCGGCACAC
GCAACTTTGCCGACGAGAGTGTTGAGCAAGCCGCCATGACCACTGAGGAGCGCGACCGCGCCATGGCGCTCGGCGCGCAA
CGCGTGGCACACCATGCTGCGCTTGGCACCAACGTGATCGCGCTGGGCGAAATGGGCATCGCCAATACGGCGTCTGCCGC
GTGCCTGATGGCGCGCTTATGCAATTTGCCGGTCGCGCAATGCGTTGGCCGCGGCACCGGGCTCGATGATGACGGCCTGG
CCCACAAGCGCGCCGTGCTGGAAGCAGCGATGGCCAGGCACGCTGACGTACGCGAGCCGCTGGACGTGCTTGCGTGCTTC
GGCGGCTTCGAGGTCGCAGCGATGGTGGGGGCGGTGCTTGAGGCGGCGCAGCGCCGCATGGTCATCCTCGTCGACGGGTT
TATCGCGACGGCCGCCGTGCTGGTGGCCGCGCACGTGGCGCCCGATGTGCTGCGCTTCTGCGTGTTCGGGCATGTGTCGG
ACGAGCGCGGGCATCGCGCCTTGCTGGAGCTGCTCGATGCGCGGCCGCTGCTGTCGCTGTCGTTGCGGCTGGGCGAGGGC
AGCGGCGCGGTGTTGGCGTATCCGGTGGTCGTGTCGGCGGTGGCGTTCCTGCGCGAAATGGCGACCTTCGCCAGCGCAGG
CGTGAGCGAGCGCGCATCGCCATGA

Upstream 100 bases:

>100_bases
CACCCGAGCTGATCGAGGCGGCGGATACCGTGACCGACATGACGCTCGTCAAGCACGCCTTTTCCCGAGGCATCCAGGCC
CAGCCCGGAGTCGAATTGTG

Downstream 100 bases:

>100_bases
ACGCGTTGCGCGAACATTGGCAGGCGCTGTGGACGGCCGTCGGGTATTTCACCCGCATCCCCGTGCCGGCGTCGGTTGGG
TTCTCGCAAGCGGGCTTGAA

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MNQTMYIPPFDDALRVRLQAAVDSKTKPLGALGRLESLAVQIGLIQNTDTPQLTRPAMVVFAADHGIAHAGVSAYPQAVT
AQMVLNFIAGGAAVNVFCRQHGFALEVVNAGVAAPLWAADAPGLVDAPVGPGTRNFADESVEQAAMTTEERDRAMALGAQ
RVAHHAALGTNVIALGEMGIANTASAACLMARLCNLPVAQCVGRGTGLDDDGLAHKRAVLEAAMARHADVREPLDVLACF
GGFEVAAMVGAVLEAAQRRMVILVDGFIATAAVLVAAHVAPDVLRFCVFGHVSDERGHRALLELLDARPLLSLSLRLGEG
SGAVLAYPVVVSAVAFLREMATFASAGVSERASP

Sequences:

>Translated_354_residues
MNQTMYIPPFDDALRVRLQAAVDSKTKPLGALGRLESLAVQIGLIQNTDTPQLTRPAMVVFAADHGIAHAGVSAYPQAVT
AQMVLNFIAGGAAVNVFCRQHGFALEVVNAGVAAPLWAADAPGLVDAPVGPGTRNFADESVEQAAMTTEERDRAMALGAQ
RVAHHAALGTNVIALGEMGIANTASAACLMARLCNLPVAQCVGRGTGLDDDGLAHKRAVLEAAMARHADVREPLDVLACF
GGFEVAAMVGAVLEAAQRRMVILVDGFIATAAVLVAAHVAPDVLRFCVFGHVSDERGHRALLELLDARPLLSLSLRLGEG
SGAVLAYPVVVSAVAFLREMATFASAGVSERASP
>Mature_354_residues
MNQTMYIPPFDDALRVRLQAAVDSKTKPLGALGRLESLAVQIGLIQNTDTPQLTRPAMVVFAADHGIAHAGVSAYPQAVT
AQMVLNFIAGGAAVNVFCRQHGFALEVVNAGVAAPLWAADAPGLVDAPVGPGTRNFADESVEQAAMTTEERDRAMALGAQ
RVAHHAALGTNVIALGEMGIANTASAACLMARLCNLPVAQCVGRGTGLDDDGLAHKRAVLEAAMARHADVREPLDVLACF
GGFEVAAMVGAVLEAAQRRMVILVDGFIATAAVLVAAHVAPDVLRFCVFGHVSDERGHRALLELLDARPLLSLSLRLGEG
SGAVLAYPVVVSAVAFLREMATFASAGVSERASP

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=344, Percent_Identity=32.5581395348837, Blast_Score=170, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 36781; Mature: 36781

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQTMYIPPFDDALRVRLQAAVDSKTKPLGALGRLESLAVQIGLIQNTDTPQLTRPAMVV
CCCCEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEEEEECCCCCCCCCCEEEE
FAADHGIAHAGVSAYPQAVTAQMVLNFIAGGAAVNVFCRQHGFALEVVNAGVAAPLWAAD
EEECCCCHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEECCCCCCCCCCCC
APGLVDAPVGPGTRNFADESVEQAAMTTEERDRAMALGAQRVAHHAALGTNVIALGEMGI
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCC
ANTASAACLMARLCNLPVAQCVGRGTGLDDDGLAHKRAVLEAAMARHADVREPLDVLACF
CCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHH
GGFEVAAMVGAVLEAAQRRMVILVDGFIATAAVLVAAHVAPDVLRFCVFGHVSDERGHRA
CCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
LLELLDARPLLSLSLRLGEGSGAVLAYPVVVSAVAFLREMATFASAGVSERASP
HHHHHCCCCCEEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNQTMYIPPFDDALRVRLQAAVDSKTKPLGALGRLESLAVQIGLIQNTDTPQLTRPAMVV
CCCCEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEEEEECCCCCCCCCCEEEE
FAADHGIAHAGVSAYPQAVTAQMVLNFIAGGAAVNVFCRQHGFALEVVNAGVAAPLWAAD
EEECCCCHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEECCCCCCCCCCCC
APGLVDAPVGPGTRNFADESVEQAAMTTEERDRAMALGAQRVAHHAALGTNVIALGEMGI
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCC
ANTASAACLMARLCNLPVAQCVGRGTGLDDDGLAHKRAVLEAAMARHADVREPLDVLACF
CCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHH
GGFEVAAMVGAVLEAAQRRMVILVDGFIATAAVLVAAHVAPDVLRFCVFGHVSDERGHRA
CCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
LLELLDARPLLSLSLRLGEGSGAVLAYPVVVSAVAFLREMATFASAGVSERASP
HHHHHCCCCCEEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]