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The map label for this gene is fdhB1 [H]

Identifier: 187929657

GI number: 187929657

Start: 2693843

End: 2694511

Strand: Reverse

Name: fdhB1 [H]

Synonym: Rpic_2585

Alternate gene names: 187929657

Gene position: 2694511-2693843 (Counterclockwise)

Preceding gene: 187929658

Following gene: 187929656

Centisome position: 68.34

GC content: 65.77

Gene sequence:

>669_bases
ATGGCACGTATGAAATTCATCTGTGACAGCGAGCGCTGCATCGAATGCAACGCCTGCGCCACGGCCTGCAAGAACGAACA
CGAGGTGCCCTGGGGCGTGAACCGTCGCCGCGTGGTGACGATCAACGACGGCATGATCGGCGCGGAGAAATCCATCTCGG
TGGCGTGCATGCATTGCTCCGATGCGCCGTGCATGGCGGTCTGCCCGGTCGACTGCTTCTACCGCACCGAAGACGGCGTG
GTGCTGCACGACAAGGACGTCTGCATCGGCTGCGGCTACTGCTCGTATGCGTGCCCGTTCGGCGCGCCGCAGTTCCCGAG
CCAGGGCACGTTTGGCGTGCGCGGCAAGATGGACAAGTGCACGTTCTGCGCGGGCGGCCCCGAGAAGAACGGCAGCGAGG
AAGAATTCGAAAAGTACGGCCGCAACCGCCTGGCCGAAGGGAAGCTTCCGCTGTGCGCGGAAATGTGCTCGACGAAGGCG
CTGCTCGGCGGCGACGGCGATGTGATTTCCGACATCCTGCGTAACCGGGTCATGAAGCGCGGGAAGGGCGCGGAGTTGTT
CGGGTGGGGCACGGCCTATGGCGGCGCGCAGGGCAAGGGCGGTCAGGCGGCACCGGCAACTCCGGCCGCACCGGCCAAGC
CGGCTTCGGCGTCGGGAGCGCAATCATGA

Upstream 100 bases:

>100_bases
ACGGCCACGACCTACGGCTACGACTCGGTGACGATGATGCAGGAAACGAAAACGACGGTCTGCCAGATCGAGCGGTTCGC
ATAAGGACGGGGAGATCAAC

Downstream 100 bases:

>100_bases
GCGCCCCCGCACGATCGACCAGCCTGGTGATCGCCCTTGGTGCTGTGCTGTTGCTCGGTGCCTGCGGTGAACGCCCGCAA
ACGGCATTCGCCTCGCACCG

Product: 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein

Products: CO2; NADH

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MARMKFICDSERCIECNACATACKNEHEVPWGVNRRRVVTINDGMIGAEKSISVACMHCSDAPCMAVCPVDCFYRTEDGV
VLHDKDVCIGCGYCSYACPFGAPQFPSQGTFGVRGKMDKCTFCAGGPEKNGSEEEFEKYGRNRLAEGKLPLCAEMCSTKA
LLGGDGDVISDILRNRVMKRGKGAELFGWGTAYGGAQGKGGQAAPATPAAPAKPASASGAQS

Sequences:

>Translated_222_residues
MARMKFICDSERCIECNACATACKNEHEVPWGVNRRRVVTINDGMIGAEKSISVACMHCSDAPCMAVCPVDCFYRTEDGV
VLHDKDVCIGCGYCSYACPFGAPQFPSQGTFGVRGKMDKCTFCAGGPEKNGSEEEFEKYGRNRLAEGKLPLCAEMCSTKA
LLGGDGDVISDILRNRVMKRGKGAELFGWGTAYGGAQGKGGQAAPATPAAPAKPASASGAQS
>Mature_221_residues
ARMKFICDSERCIECNACATACKNEHEVPWGVNRRRVVTINDGMIGAEKSISVACMHCSDAPCMAVCPVDCFYRTEDGVV
LHDKDVCIGCGYCSYACPFGAPQFPSQGTFGVRGKMDKCTFCAGGPEKNGSEEEFEKYGRNRLAEGKLPLCAEMCSTKAL
LGGDGDVISDILRNRVMKRGKGAELFGWGTAYGGAQGKGGQAAPATPAAPAKPASASGAQS

Specific function: This chain is an electron transfer unit containing 18 cysteine residues, 16 of which occur in four clusters [H]

COG id: COG0437

COG function: function code C; Fe-S-cluster-containing hydrogenase components 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1787122, Length=174, Percent_Identity=35.0574712643678, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1787872, Length=169, Percent_Identity=35.5029585798817, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI226510944, Length=170, Percent_Identity=35.2941176470588, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI2367345, Length=191, Percent_Identity=33.5078534031414, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789370, Length=184, Percent_Identity=29.8913043478261, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1789079, Length=226, Percent_Identity=29.646017699115, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082114, Length=181, Percent_Identity=28.7292817679558, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790326, Length=192, Percent_Identity=26.0416666666667, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87082180, Length=185, Percent_Identity=30.8108108108108, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788811, Length=180, Percent_Identity=27.2222222222222, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI2367245, Length=155, Percent_Identity=33.5483870967742, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787749, Length=208, Percent_Identity=26.4423076923077, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR000813 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: 1.2.1.2

Molecular weight: Translated: 23447; Mature: 23316

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

8.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
11.7 %Cys+Met (Translated Protein)
8.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
11.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARMKFICDSERCIECNACATACKNEHEVPWGVNRRRVVTINDGMIGAEKSISVACMHCS
CCCCEEEECCCCEEEHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEECC
DAPCMAVCPVDCFYRTEDGVVLHDKDVCIGCGYCSYACPFGAPQFPSQGTFGVRGKMDKC
CCCEEEECCCEEEEECCCCEEEECCCEEEECCCHHCCCCCCCCCCCCCCCCCCCCCCCCE
TFCAGGPEKNGSEEEFEKYGRNRLAEGKLPLCAEMCSTKALLGGDGDVISDILRNRVMKR
EEECCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHCCCEEECCCHHHHHHHHHHHHHHC
GKGAELFGWGTAYGGAQGKGGQAAPATPAAPAKPASASGAQS
CCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ARMKFICDSERCIECNACATACKNEHEVPWGVNRRRVVTINDGMIGAEKSISVACMHCS
CCCEEEECCCCEEEHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEECC
DAPCMAVCPVDCFYRTEDGVVLHDKDVCIGCGYCSYACPFGAPQFPSQGTFGVRGKMDKC
CCCEEEECCCEEEEECCCCEEEECCCEEEECCCHHCCCCCCCCCCCCCCCCCCCCCCCCE
TFCAGGPEKNGSEEEFEKYGRNRLAEGKLPLCAEMCSTKALLGGDGDVISDILRNRVMKR
EEECCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHCCCEEECCCHHHHHHHHHHHHHHC
GKGAELFGWGTAYGGAQGKGGQAAPATPAAPAKPASASGAQS
CCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formate; NAD+

Specific reaction: formate + NAD+ = CO2 + NADH

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1781728; 14500908 [H]