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The map label for this gene is fdhD [H]

Identifier: 187929652

GI number: 187929652

Start: 2690455

End: 2691330

Strand: Reverse

Name: fdhD [H]

Synonym: Rpic_2580

Alternate gene names: 187929652

Gene position: 2691330-2690455 (Counterclockwise)

Preceding gene: 187929653

Following gene: 187929651

Centisome position: 68.26

GC content: 66.1

Gene sequence:

>876_bases
ATGCCGCTGCGCCCCGAACTGACCAACGCTTCTGTTCCACTGCTCGACGAGGTTGAAGTGCTCGACGAGCTGGGCCGCGC
ACGCCATGTCTACATCCCTGGTGAACGCCCGCTCACGGTCTATCTCGACAAGCGCGAACTCGTCACGCTGATGACGCTGG
GCGGCGCGCCCGAAGCGCTCGTACTCGGCTATCTGCGTAACCAGCGCCTGGTCAGCAGCATCGAAGACATCGCCTCCATC
CAGGTCGATTGGGAAACCGAATCGGCTGCCGTGTCCACGCGCGCCGGCATCGCCGACCTGGACGAGAAGACCGCCCGCCG
CACCGTGACCACCGGCTGCGGGCAAGGCACCGTGTTTGGCTCGCTGATGGACGAGATCGACGCCATCCATCTGCCGCCCG
ACGCGCGCATGACGCAGACCACGCTGTACCGCGTGGTGGACGCCATCCGCCTGCAGCAGTCGATCTACAAGCAGGCGGGC
TCCGTGCATGGCTGCGCGCTGTTCGATGCGCACGGCCAGCTGCTGCATTTCATTGAAGACGTGGGCCGCCACAATGCCGT
GGATGCCATCGCCGGCCGCATGTGGCTTGAGGGCATGGAGGGCGGCGACAAGATCTTCTACACCACCGGCCGCCTGACCT
CCGAGATGGTCATCAAGGGCGCGCAGATGGGCATTCCGTTCCTGTTGTCGCGCTCAGGTGTCACGCAGATGGGCCACCAG
ATGGCGCAGCGGGTCAACCTGACGCTGTTTGCGCGGTGCACGGGGCGGCACTTTCTGCTCTACACGGGGCGGGACCGTTT
TGTGGCCGAGCCGGGAGTGGCCGGCATGGTCGGGCCGCGCGGGGAACTGCTTCAGGCGGCGGAATCCGGCCGCTGA

Upstream 100 bases:

>100_bases
GGCGAACTGATCGCCCGCACGCGGTACCTGCTCTCGGGCAGGTACCAACCGCAGCATGCGCACGCTCGCCGTGCGCATTT
TTATTTGAACGAAGACATCG

Downstream 100 bases:

>100_bases
TCCGCTCGCGTTTGCCCGGATAAGGCCAGCGCAAGCCATCGGCCGCCACGGGGTTTTCCGTCACAGGTTTGGGAGTACAA
TCCGCGTTCCAAACCGGCCC

Product: formate dehydrogenase subunit FdhD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MPLRPELTNASVPLLDEVEVLDELGRARHVYIPGERPLTVYLDKRELVTLMTLGGAPEALVLGYLRNQRLVSSIEDIASI
QVDWETESAAVSTRAGIADLDEKTARRTVTTGCGQGTVFGSLMDEIDAIHLPPDARMTQTTLYRVVDAIRLQQSIYKQAG
SVHGCALFDAHGQLLHFIEDVGRHNAVDAIAGRMWLEGMEGGDKIFYTTGRLTSEMVIKGAQMGIPFLLSRSGVTQMGHQ
MAQRVNLTLFARCTGRHFLLYTGRDRFVAEPGVAGMVGPRGELLQAAESGR

Sequences:

>Translated_291_residues
MPLRPELTNASVPLLDEVEVLDELGRARHVYIPGERPLTVYLDKRELVTLMTLGGAPEALVLGYLRNQRLVSSIEDIASI
QVDWETESAAVSTRAGIADLDEKTARRTVTTGCGQGTVFGSLMDEIDAIHLPPDARMTQTTLYRVVDAIRLQQSIYKQAG
SVHGCALFDAHGQLLHFIEDVGRHNAVDAIAGRMWLEGMEGGDKIFYTTGRLTSEMVIKGAQMGIPFLLSRSGVTQMGHQ
MAQRVNLTLFARCTGRHFLLYTGRDRFVAEPGVAGMVGPRGELLQAAESGR
>Mature_290_residues
PLRPELTNASVPLLDEVEVLDELGRARHVYIPGERPLTVYLDKRELVTLMTLGGAPEALVLGYLRNQRLVSSIEDIASIQ
VDWETESAAVSTRAGIADLDEKTARRTVTTGCGQGTVFGSLMDEIDAIHLPPDARMTQTTLYRVVDAIRLQQSIYKQAGS
VHGCALFDAHGQLLHFIEDVGRHNAVDAIAGRMWLEGMEGGDKIFYTTGRLTSEMVIKGAQMGIPFLLSRSGVTQMGHQM
AQRVNLTLFARCTGRHFLLYTGRDRFVAEPGVAGMVGPRGELLQAAESGR

Specific function: Necessary for formate dehydrogenase activity [H]

COG id: COG1526

COG function: function code C; Uncharacterized protein required for formate dehydrogenase activity

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fdhD family [H]

Homologues:

Organism=Escherichia coli, GI1790329, Length=255, Percent_Identity=28.2352941176471, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003786 [H]

Pfam domain/function: PF02634 FdhD-NarQ [H]

EC number: NA

Molecular weight: Translated: 31848; Mature: 31717

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLRPELTNASVPLLDEVEVLDELGRARHVYIPGERPLTVYLDKRELVTLMTLGGAPEAL
CCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCEEEEECCCCEEEEEECCCCCHHH
VLGYLRNQRLVSSIEDIASIQVDWETESAAVSTRAGIADLDEKTARRTVTTGCGQGTVFG
HHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHH
SLMDEIDAIHLPPDARMTQTTLYRVVDAIRLQQSIYKQAGSVHGCALFDAHGQLLHFIED
HHHHHHCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHH
VGRHNAVDAIAGRMWLEGMEGGDKIFYTTGRLTSEMVIKGAQMGIPFLLSRSGVTQMGHQ
HCCCCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEECCCCHHHHHHH
MAQRVNLTLFARCTGRHFLLYTGRDRFVAEPGVAGMVGPRGELLQAAESGR
HHHHCCEEEEEEECCCEEEEEECCCCEEECCCCCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
PLRPELTNASVPLLDEVEVLDELGRARHVYIPGERPLTVYLDKRELVTLMTLGGAPEAL
CCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCEEEEECCCCEEEEEECCCCCHHH
VLGYLRNQRLVSSIEDIASIQVDWETESAAVSTRAGIADLDEKTARRTVTTGCGQGTVFG
HHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHH
SLMDEIDAIHLPPDARMTQTTLYRVVDAIRLQQSIYKQAGSVHGCALFDAHGQLLHFIED
HHHHHHCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHH
VGRHNAVDAIAGRMWLEGMEGGDKIFYTTGRLTSEMVIKGAQMGIPFLLSRSGVTQMGHQ
HCCCCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEECCCCHHHHHHH
MAQRVNLTLFARCTGRHFLLYTGRDRFVAEPGVAGMVGPRGELLQAAESGR
HHHHCCEEEEEEECCCEEEEEECCCCEEECCCCCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]