Click here to switch to the map view.

The map label for this gene is ppa [H]

Identifier: 187929638

GI number: 187929638

Start: 2671088

End: 2671615

Strand: Reverse

Name: ppa [H]

Synonym: Rpic_2565

Alternate gene names: 187929638

Gene position: 2671615-2671088 (Counterclockwise)

Preceding gene: 187929642

Following gene: 187929637

Centisome position: 67.76

GC content: 61.36

Gene sequence:

>528_bases
ATGAGCTTCAACAACGTCTCGCCGGGCAAGGACATCCCCAACGATTTCAACGTCATCATCGAGATCCCGGCGCAGAGCGA
CCCGGTCAAGTACGAAGCCGACAAGGAAACCGGCCTGCTGTTCGTAGACCGCTTCGTTGGCACCGGCATGCGCTACCCGG
CCAACTACGGCTTCATCCCGCAGACGCTCTCGGGCGACGGTGACCCGGTCGACGTGCTGGTCGTCACGCCGTTCCCGCTC
ATCCACGGTTGCGTGGTGCGCTGCCGTGCCCTGGGCATGCTGAAGATGACGGATGAATCCGGTGTGGACGCCAAGCTGGT
TGCCGTGCCTGTCAACAAGCTGAGCCCGGCGACGGCCCACGTGACCGACCTGTCGGACATCGGCCAGAACCTGCTGGACC
AGATCAAGCACTTCTTCGAGCACTACAAGGCGCTGGAAGCCGGCAAGTGGGTCAAGGTCGAAGGCTGGGGCGGTATTGAA
GAAGCCCACAAGGAAATCGCCGACGGCGTTGCCAACTATAAGAAGTAA

Upstream 100 bases:

>100_bases
CGAGTGTGAGGGGCTATAATGCCCGCCGACAGTTTTTCACGCTTCTTTCCAACCATTTGCGTCGCGTTTTTACGCACTTC
GCGCATTCCGGAGCATTTCC

Downstream 100 bases:

>100_bases
GCTGTTTCAGGATTTTGCCGTACGGCATGTCTGACAAATCCCGGCCTCCGGATGGAGTGCCGGGATTTTTTCTTTGCAAA
GCCGTCATCGATGTAACGCA

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MSFNNVSPGKDIPNDFNVIIEIPAQSDPVKYEADKETGLLFVDRFVGTGMRYPANYGFIPQTLSGDGDPVDVLVVTPFPL
IHGCVVRCRALGMLKMTDESGVDAKLVAVPVNKLSPATAHVTDLSDIGQNLLDQIKHFFEHYKALEAGKWVKVEGWGGIE
EAHKEIADGVANYKK

Sequences:

>Translated_175_residues
MSFNNVSPGKDIPNDFNVIIEIPAQSDPVKYEADKETGLLFVDRFVGTGMRYPANYGFIPQTLSGDGDPVDVLVVTPFPL
IHGCVVRCRALGMLKMTDESGVDAKLVAVPVNKLSPATAHVTDLSDIGQNLLDQIKHFFEHYKALEAGKWVKVEGWGGIE
EAHKEIADGVANYKK
>Mature_174_residues
SFNNVSPGKDIPNDFNVIIEIPAQSDPVKYEADKETGLLFVDRFVGTGMRYPANYGFIPQTLSGDGDPVDVLVVTPFPLI
HGCVVRCRALGMLKMTDESGVDAKLVAVPVNKLSPATAHVTDLSDIGQNLLDQIKHFFEHYKALEAGKWVKVEGWGGIEE
AHKEIADGVANYKK

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=175, Percent_Identity=61.7142857142857, Blast_Score=218, Evalue=2e-58,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 19128; Mature: 18997

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFNNVSPGKDIPNDFNVIIEIPAQSDPVKYEADKETGLLFVDRFVGTGMRYPANYGFIP
CCCCCCCCCCCCCCCCEEEEECCCCCCCEEEECCCCCCEEEEEHHHCCCCCCCCCCCCCC
QTLSGDGDPVDVLVVTPFPLIHGCVVRCRALGMLKMTDESGVDAKLVAVPVNKLSPATAH
CCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCEEECCCCCCCEEEEEEECCCCCCCHHH
VTDLSDIGQNLLDQIKHFFEHYKALEAGKWVKVEGWGGIEEAHKEIADGVANYKK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SFNNVSPGKDIPNDFNVIIEIPAQSDPVKYEADKETGLLFVDRFVGTGMRYPANYGFIP
CCCCCCCCCCCCCCCEEEEECCCCCCCEEEECCCCCCEEEEEHHHCCCCCCCCCCCCCC
QTLSGDGDPVDVLVVTPFPLIHGCVVRCRALGMLKMTDESGVDAKLVAVPVNKLSPATAH
CCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCEEECCCCCCCEEEEEEECCCCCCCHHH
VTDLSDIGQNLLDQIKHFFEHYKALEAGKWVKVEGWGGIEEAHKEIADGVANYKK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]