Click here to switch to the map view.

The map label for this gene is adhR [H]

Identifier: 187929555

GI number: 187929555

Start: 2592996

End: 2593553

Strand: Reverse

Name: adhR [H]

Synonym: Rpic_2478

Alternate gene names: 187929555

Gene position: 2593553-2592996 (Counterclockwise)

Preceding gene: 187929556

Following gene: 187929554

Centisome position: 65.78

GC content: 64.52

Gene sequence:

>558_bases
ATGACCACATTCCTGACCATCGCCCAAGTTGCAGAAGCCACCGGCCTGTCGACGCATACGTTGCGCTATTACGAGCGCAT
AGGCCTGCTCGACAGCGTGCAGCGGCGCGATAACGGCCATCGTGTCTTCCGTGCCGAAGACATGACCTGGCTGGAGTTCC
TGCTGCGCCTGCGCGATACCGGCATGCCGATCGCGCAGATGCAGGCGTACGCCGCGCTGCGGCGGCAGGGCGACAGTCTG
GACAGTGTGTCGGCGCGCCAACGCCTGCTGGAGTTGCATGCGGCGGCGCTGGAAGCGGAGCTGCGCGCGCGGGCCGAGAC
GCTGGCCGTGCTGCGCGTCAAACTCGTTGTCTACGACGGCATCCGGGCACGGATTGAAGCCGCGGAAGGCGCGAAGGGCT
CTGCTTCCCCATCTGTCAAATCGAAGCACCAGCCAAAACGCCAACCGAACGAGGACGCACATGACCCCGACCACGCACAC
CGCACAAGCCGCAAACCACGCCAATCTGCAGGACGACCGCTACGCACGGGGCTGGCAAAAGCTCAAGGAAGTCGATGA

Upstream 100 bases:

>100_bases
CGGCCTCCGAGAAGGGGCCGGCGCTTTGTTTTGTGCGGGCCGGAAGAGTTCGCGTAAAGTCGCTTGACTTAGAGTGCGCT
CTAACTTCTAAGCTCCGTTC

Downstream 100 bases:

>100_bases
TGTTGCCGGCGAGCGCGTGGTCGAGGCCTTGGCCGATATTTCGCCCGACCTCGGCCGCTACGTCGTCGAGTTCGGCTTTG
GCGACGTCTATAGCCGCCCG

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MTTFLTIAQVAEATGLSTHTLRYYERIGLLDSVQRRDNGHRVFRAEDMTWLEFLLRLRDTGMPIAQMQAYAALRRQGDSL
DSVSARQRLLELHAAALEAELRARAETLAVLRVKLVVYDGIRARIEAAEGAKGSASPSVKSKHQPKRQPNEDAHDPDHAH
RTSRKPRQSAGRPLRTGLAKAQGSR

Sequences:

>Translated_185_residues
MTTFLTIAQVAEATGLSTHTLRYYERIGLLDSVQRRDNGHRVFRAEDMTWLEFLLRLRDTGMPIAQMQAYAALRRQGDSL
DSVSARQRLLELHAAALEAELRARAETLAVLRVKLVVYDGIRARIEAAEGAKGSASPSVKSKHQPKRQPNEDAHDPDHAH
RTSRKPRQSAGRPLRTGLAKAQGSR
>Mature_184_residues
TTFLTIAQVAEATGLSTHTLRYYERIGLLDSVQRRDNGHRVFRAEDMTWLEFLLRLRDTGMPIAQMQAYAALRRQGDSLD
SVSARQRLLELHAAALEAELRARAETLAVLRVKLVVYDGIRARIEAAEGAKGSASPSVKSKHQPKRQPNEDAHDPDHAHR
TSRKPRQSAGRPLRTGLAKAQGSR

Specific function: Transcriptional regulator involved in the response to aldehyde stress. Binds to the promoter region of the adhA-yraA operon, the yraC and its own promoter region; binding is unchanged in the presence of aldehydes [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 20657; Mature: 20526

Theoretical pI: Translated: 11.07; Mature: 11.07

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTFLTIAQVAEATGLSTHTLRYYERIGLLDSVQRRDNGHRVFRAEDMTWLEFLLRLRDT
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHC
GMPIAQMQAYAALRRQGDSLDSVSARQRLLELHAAALEAELRARAETLAVLRVKLVVYDG
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IRARIEAAEGAKGSASPSVKSKHQPKRQPNEDAHDPDHAHRTSRKPRQSAGRPLRTGLAK
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHCCCHHHHHHHH
AQGSR
CCCCC
>Mature Secondary Structure 
TTFLTIAQVAEATGLSTHTLRYYERIGLLDSVQRRDNGHRVFRAEDMTWLEFLLRLRDT
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHC
GMPIAQMQAYAALRRQGDSLDSVSARQRLLELHAAALEAELRARAETLAVLRVKLVVYDG
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IRARIEAAEGAKGSASPSVKSKHQPKRQPNEDAHDPDHAHRTSRKPRQSAGRPLRTGLAK
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHCCCHHHHHHHH
AQGSR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9141695; 9384377 [H]