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The map label for this gene is zupT [H]

Identifier: 187929511

GI number: 187929511

Start: 2537779

End: 2538585

Strand: Reverse

Name: zupT [H]

Synonym: Rpic_2432

Alternate gene names: 187929511

Gene position: 2538585-2537779 (Counterclockwise)

Preceding gene: 187929512

Following gene: 187929507

Centisome position: 64.39

GC content: 61.59

Gene sequence:

>807_bases
ATGACCTTCGATACCACCCTGTTAGGCATTCTCCTGGCCACTGCGCTGTCTGGCATCGGCAGCATGGCGGGCGCTGCCGC
GCTGTCTCTGACCGTGCTGTCGCGCATGGTCGATCGGATGGTCAGTTTCTCGGTGGGCGTGCTGCTGGCCACGTCGCTGC
TGCATTCGTTGCCGGAGGCGTTCGAAGCCCATCGCGGCATCGAGCCCAATACGCATGCGTTGTTCGCCACGTTGCTCGCC
GGGCTGCTGGGTTTTTTCCTGCTGGAAAAGATCTCACTGATCCGCCATTCACATCACCACGAGGGTGATGGGCACGGCCA
TCACCACGGCCATGACCGGCAGGAAGCCGGGCGCAGTGGCCTGATGATCCTCGTGGGCGATGGGCTGCATAATTTTTCGG
ACGGGATCGTGATTGCGGCGGCGTTCCTGGCGGACACTAAGGTCGGCATCGTCACGGCGCTGGCGATTGCTGCACACGAG
ATCCCGCAAGAGATCGGCGACTTCATGGTGCTACTCAACGCCGGGTTTTCCAAGACGCGCGCCTTTGTCTACAACCTGAT
CTGCAGCGTTTGCGCGCTGGTGGGCGCGGTGCTGGGTTACTACCTGCTGGACCGCCTGACGTCGTGGATTCCATACGTGC
TCGTGGTGGCGTCGAGCAGCTTCATCTACATCGCCGTATGCGATCTCATGCCGCAGATGAAGCGCCGGCCGCGCTGGCAG
GAATCGGCGGTGCAGGTCGCCTTGATTACGGCGGGCATCGCGATGATCTTTCTGCTGACCGAAGGTTTGCACGGTCACGC
ACATTGA

Upstream 100 bases:

>100_bases
TTTTCTTTTGCCTGCACTGGCAAAGGTTGGCAAAGCGGCATACAATCCGCCCTTCTTGCAACTCTGTTGCGTTTATTGGC
TCCCGCTGCGTCACCTCCGC

Downstream 100 bases:

>100_bases
GGCGGCGCATCGGCTTCAAGAAAAAGCCCGGTCGATATCGGGCTTTTTGCTGCGCGCCGGATTCGCAGATTACGGATTCG
GCCCCGTCGCCACCGGGCGC

Product: zinc/iron permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MTFDTTLLGILLATALSGIGSMAGAAALSLTVLSRMVDRMVSFSVGVLLATSLLHSLPEAFEAHRGIEPNTHALFATLLA
GLLGFFLLEKISLIRHSHHHEGDGHGHHHGHDRQEAGRSGLMILVGDGLHNFSDGIVIAAAFLADTKVGIVTALAIAAHE
IPQEIGDFMVLLNAGFSKTRAFVYNLICSVCALVGAVLGYYLLDRLTSWIPYVLVVASSSFIYIAVCDLMPQMKRRPRWQ
ESAVQVALITAGIAMIFLLTEGLHGHAH

Sequences:

>Translated_268_residues
MTFDTTLLGILLATALSGIGSMAGAAALSLTVLSRMVDRMVSFSVGVLLATSLLHSLPEAFEAHRGIEPNTHALFATLLA
GLLGFFLLEKISLIRHSHHHEGDGHGHHHGHDRQEAGRSGLMILVGDGLHNFSDGIVIAAAFLADTKVGIVTALAIAAHE
IPQEIGDFMVLLNAGFSKTRAFVYNLICSVCALVGAVLGYYLLDRLTSWIPYVLVVASSSFIYIAVCDLMPQMKRRPRWQ
ESAVQVALITAGIAMIFLLTEGLHGHAH
>Mature_267_residues
TFDTTLLGILLATALSGIGSMAGAAALSLTVLSRMVDRMVSFSVGVLLATSLLHSLPEAFEAHRGIEPNTHALFATLLAG
LLGFFLLEKISLIRHSHHHEGDGHGHHHGHDRQEAGRSGLMILVGDGLHNFSDGIVIAAAFLADTKVGIVTALAIAAHEI
PQEIGDFMVLLNAGFSKTRAFVYNLICSVCALVGAVLGYYLLDRLTSWIPYVLVVASSSFIYIAVCDLMPQMKRRPRWQE
SAVQVALITAGIAMIFLLTEGLHGHAH

Specific function: Mediates zinc uptake. May also transport other divalent cations [H]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily [H]

Homologues:

Organism=Homo sapiens, GI187936949, Length=158, Percent_Identity=36.0759493670886, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI55741750, Length=158, Percent_Identity=36.0759493670886, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI223633937, Length=258, Percent_Identity=31.3953488372093, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI223633939, Length=295, Percent_Identity=28.8135593220339, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI40255101, Length=260, Percent_Identity=28.8461538461538, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI190014617, Length=267, Percent_Identity=28.8389513108614, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI153252201, Length=131, Percent_Identity=35.8778625954198, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI190358541, Length=127, Percent_Identity=34.6456692913386, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI205830424, Length=127, Percent_Identity=34.6456692913386, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI190360568, Length=127, Percent_Identity=34.6456692913386, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI153252214, Length=128, Percent_Identity=35.15625, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI115430255, Length=121, Percent_Identity=41.3223140495868, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI115430259, Length=121, Percent_Identity=41.3223140495868, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI205830426, Length=116, Percent_Identity=36.2068965517241, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI24586665, Length=161, Percent_Identity=31.055900621118, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI205830403, Length=161, Percent_Identity=31.055900621118, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI205830407, Length=160, Percent_Identity=31.25, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI205830405, Length=129, Percent_Identity=34.1085271317829, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI206597541, Length=139, Percent_Identity=39.568345323741, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI206597539, Length=139, Percent_Identity=39.568345323741, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI117553619, Length=127, Percent_Identity=34.6456692913386, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI117553608, Length=127, Percent_Identity=34.6456692913386, Blast_Score=75, Evalue=5e-14,
Organism=Escherichia coli, GI1789419, Length=259, Percent_Identity=26.6409266409266, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI193209531, Length=226, Percent_Identity=30.0884955752212, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI71992548, Length=140, Percent_Identity=33.5714285714286, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71994730, Length=277, Percent_Identity=27.0758122743682, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71998183, Length=142, Percent_Identity=36.6197183098592, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17538884, Length=110, Percent_Identity=35.4545454545455, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI32566718, Length=121, Percent_Identity=25.6198347107438, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI32566720, Length=121, Percent_Identity=25.6198347107438, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322166, Length=247, Percent_Identity=28.3400809716599, Blast_Score=85, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24664383, Length=117, Percent_Identity=42.7350427350427, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI161083817, Length=117, Percent_Identity=42.7350427350427, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI45549201, Length=114, Percent_Identity=42.1052631578947, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24651189, Length=281, Percent_Identity=26.6903914590747, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24651193, Length=281, Percent_Identity=26.6903914590747, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24651187, Length=281, Percent_Identity=26.6903914590747, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24651191, Length=281, Percent_Identity=26.6903914590747, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24651195, Length=281, Percent_Identity=26.6903914590747, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24651197, Length=281, Percent_Identity=26.6903914590747, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI17864610, Length=144, Percent_Identity=32.6388888888889, Blast_Score=85, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 28724; Mature: 28593

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFDTTLLGILLATALSGIGSMAGAAALSLTVLSRMVDRMVSFSVGVLLATSLLHSLPEA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEAHRGIEPNTHALFATLLAGLLGFFLLEKISLIRHSHHHEGDGHGHHHGHDRQEAGRSG
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCC
LMILVGDGLHNFSDGIVIAAAFLADTKVGIVTALAIAAHEIPQEIGDFMVLLNAGFSKTR
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AFVYNLICSVCALVGAVLGYYLLDRLTSWIPYVLVVASSSFIYIAVCDLMPQMKRRPRWQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHH
ESAVQVALITAGIAMIFLLTEGLHGHAH
HHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TFDTTLLGILLATALSGIGSMAGAAALSLTVLSRMVDRMVSFSVGVLLATSLLHSLPEA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEAHRGIEPNTHALFATLLAGLLGFFLLEKISLIRHSHHHEGDGHGHHHGHDRQEAGRSG
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCC
LMILVGDGLHNFSDGIVIAAAFLADTKVGIVTALAIAAHEIPQEIGDFMVLLNAGFSKTR
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AFVYNLICSVCALVGAVLGYYLLDRLTSWIPYVLVVASSSFIYIAVCDLMPQMKRRPRWQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHH
ESAVQVALITAGIAMIFLLTEGLHGHAH
HHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA