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The map label for this gene is folE2 [H]

Identifier: 187929504

GI number: 187929504

Start: 2529985

End: 2530791

Strand: Reverse

Name: folE2 [H]

Synonym: Rpic_2425

Alternate gene names: 187929504

Gene position: 2530791-2529985 (Counterclockwise)

Preceding gene: 187929505

Following gene: 187929502

Centisome position: 64.19

GC content: 61.21

Gene sequence:

>807_bases
ATGAACGATATGAACCCGGCTTTCGCGATGCCGGACGTGCAGTCCAGCCACGATACCCGCCAGATTCCCATTCAGCGTGT
TGGCGTGCGCGGCGTGCGTTACCCGATGTCGCTGCAAACCCCTTCAGGCGTGCTGAACACCGTCGGCACGTACAATCTTG
ACGTGCATCTGCCGGCCGACCAGAAGGGCACGCACATGTCGCGCTTCGTCGCGCTGCTTGAAGAAGAGCGCGAGCCGCTG
AATCTGGCGCAGTTCCAGTTGCTGCTGGAAAAGATGCTGGAGAAGCTCGAAGCCGACGCCGGCCGCATCGAAGTCCACTT
CCCGTATTTCGTCAGCAAGACGGCCCCGGTGTCGGGCGTGCAGTCGCTGATGGACTATGAAGTGACGATGATTGGCGAAG
TGCGCGACGGCCACACCAAGGTCCGCGTCAAGGCGCTGGTGCCGGTGACGAGCTTGTGCCCATGCTCGAAGAAGATCTCG
CAGTACGGTGCGCACAACCAGCGCTCGCACATCACGATCGACGCCGAGCTGGCGGCCGATACGCCGGTCGAGGCGCTCAT
TCGCATGGCCGAAGAAGAAGCGTCGTGCGAACTGTGGGGCCTGCTCAAGCGTCCGGACGAGAAGTTCGTGACCGAGCGTG
CGTACGAAAACCCGAAGTTCGTGGAAGACCTGGTGCGCGATATCGCCATGCGCCTGAACCAGGACGATCGCATCGTCGCC
TACACGCTGGAAGCGGAAAACTTCGAGTCGATTCACAACCACAGCGCCTATGCGCTGATCGAGCGCGACAAGCGCTCCGA
CAAGTAA

Upstream 100 bases:

>100_bases
ATCACTTGAGGGGTGGTCACCGTCAGCCAGGTTCCGCGGTTTCACACTCGTTGCGTGCCGGCCGACTGCGATGGCCGGGC
GACCGTAAAGGAAACCGATC

Downstream 100 bases:

>100_bases
TCGCGCTGTGCCCCAAGAAAAAGCCGCTCAATCGAGCGGCTTTTTTTCATGCGTGCCGGATGCGGATGTCTTCGAGGTCC
CAGCGTGGCGTGACGCCGTA

Product: putative GTP cyclohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MNDMNPAFAMPDVQSSHDTRQIPIQRVGVRGVRYPMSLQTPSGVLNTVGTYNLDVHLPADQKGTHMSRFVALLEEEREPL
NLAQFQLLLEKMLEKLEADAGRIEVHFPYFVSKTAPVSGVQSLMDYEVTMIGEVRDGHTKVRVKALVPVTSLCPCSKKIS
QYGAHNQRSHITIDAELAADTPVEALIRMAEEEASCELWGLLKRPDEKFVTERAYENPKFVEDLVRDIAMRLNQDDRIVA
YTLEAENFESIHNHSAYALIERDKRSDK

Sequences:

>Translated_268_residues
MNDMNPAFAMPDVQSSHDTRQIPIQRVGVRGVRYPMSLQTPSGVLNTVGTYNLDVHLPADQKGTHMSRFVALLEEEREPL
NLAQFQLLLEKMLEKLEADAGRIEVHFPYFVSKTAPVSGVQSLMDYEVTMIGEVRDGHTKVRVKALVPVTSLCPCSKKIS
QYGAHNQRSHITIDAELAADTPVEALIRMAEEEASCELWGLLKRPDEKFVTERAYENPKFVEDLVRDIAMRLNQDDRIVA
YTLEAENFESIHNHSAYALIERDKRSDK
>Mature_268_residues
MNDMNPAFAMPDVQSSHDTRQIPIQRVGVRGVRYPMSLQTPSGVLNTVGTYNLDVHLPADQKGTHMSRFVALLEEEREPL
NLAQFQLLLEKMLEKLEADAGRIEVHFPYFVSKTAPVSGVQSLMDYEVTMIGEVRDGHTKVRVKALVPVTSLCPCSKKIS
QYGAHNQRSHITIDAELAADTPVEALIRMAEEEASCELWGLLKRPDEKFVTERAYENPKFVEDLVRDIAMRLNQDDRIVA
YTLEAENFESIHNHSAYALIERDKRSDK

Specific function: Converts GTP to 7,8-dihydroneopterin triphosphate [H]

COG id: COG1469

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase IV family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022838
- InterPro:   IPR003801
- InterPro:   IPR002042 [H]

Pfam domain/function: PF02649 DUF198 [H]

EC number: =3.5.4.16 [H]

Molecular weight: Translated: 30352; Mature: 30352

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDMNPAFAMPDVQSSHDTRQIPIQRVGVRGVRYPMSLQTPSGVLNTVGTYNLDVHLPAD
CCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHCCCEEEEEEEECCC
QKGTHMSRFVALLEEEREPLNLAQFQLLLEKMLEKLEADAGRIEVHFPYFVSKTAPVSGV
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECEEECCCCCHHHH
QSLMDYEVTMIGEVRDGHTKVRVKALVPVTSLCPCSKKISQYGAHNQRSHITIDAELAAD
HHHHHCCEEEEEEECCCCEEEEEEEECCHHHCCCCHHHHHHHCCCCCCCEEEEEECCCCC
TPVEALIRMAEEEASCELWGLLKRPDEKFVTERAYENPKFVEDLVRDIAMRLNQDDRIVA
CCHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEE
YTLEAENFESIHNHSAYALIERDKRSDK
EEECCCCHHHHHCCCEEEEEECCCCCCC
>Mature Secondary Structure
MNDMNPAFAMPDVQSSHDTRQIPIQRVGVRGVRYPMSLQTPSGVLNTVGTYNLDVHLPAD
CCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHCCCEEEEEEEECCC
QKGTHMSRFVALLEEEREPLNLAQFQLLLEKMLEKLEADAGRIEVHFPYFVSKTAPVSGV
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECEEECCCCCHHHH
QSLMDYEVTMIGEVRDGHTKVRVKALVPVTSLCPCSKKISQYGAHNQRSHITIDAELAAD
HHHHHCCEEEEEEECCCCEEEEEEEECCHHHCCCCHHHHHHHCCCCCCCEEEEEECCCCC
TPVEALIRMAEEEASCELWGLLKRPDEKFVTERAYENPKFVEDLVRDIAMRLNQDDRIVA
CCHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEE
YTLEAENFESIHNHSAYALIERDKRSDK
EEECCCCHHHHHCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]