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The map label for this gene is cutS [H]

Identifier: 187929325

GI number: 187929325

Start: 2356011

End: 2357525

Strand: Direct

Name: cutS [H]

Synonym: Rpic_2246

Alternate gene names: 187929325

Gene position: 2356011-2357525 (Clockwise)

Preceding gene: 187929323

Following gene: 187929326

Centisome position: 59.76

GC content: 65.35

Gene sequence:

>1515_bases
ATGGAGACTCAGCCCATCCGCTTCTTCCACCGCGGCCAGGTCCGCACCGTCACGGACGCCCCGATCACCCGGACGGTGCT
TCAATACCTGCGTGAAGACGCGCACTGCACTGGCACCAAGGAAGGGTGCGCCGAGGGCGATTGCGGTGCTTGTACCGTCG
TGCTCGGCGAACTGCAGGAAGATGGCAGCGTCGGACTGAAGGCCGTCAACGCATGCATCCAGTTCCTGCCTACGCTTGAC
GGCAAGGCGCTGTTCACCGTGGAAGACGTGCGCGGCAAGGACGGCACGCTGCACCCGGTGCAAGAGGCCATGGTGGAGTG
CCACGGATCCCAGTGCGGCTTCTGCACGCCGGGCTTCGTGATGTCGCTTTACGCCCTGTACGAAAACACCGGCAGCCAGG
CGCCAATCCCCTCGCGCCAGACCATCTGCGATTCGCTCACTGGCAACCTGTGCCGCTGCACCGGATACCGCCCCATCATC
GCCGCGGGCGAACGCATGTTCGAACTGCCCGCGCCGGCAGGCATCGATCGCACGCAACTGGCCGACACGCTGCGCAAGCT
GCAGCGCAACGACACCTTCAGCTATGGGCCCGTCGGCACCGAGAATGCGCCGCGCTTCTACGCACCGCGCACCGCATCAG
CTTTTGCCGCCATCAAGGCCGCGCATCCGAACATCCGCATCCTGGCCGGCAGCACCGACGTCGGCCTGTGGGTCACCAAG
CAGTTCCGCGACCTGGGCGACATCCTGTACATCGGCCAGGTGGCCGACCTGTACGCACTGCAAAAGCGTGACGGCTGGAT
CGAGATCGGCGCTGCCGTCTCGCTGGAAAAGGCCTACGAATTCCTGGCCGCGGACTACCCGGAGCTGACCGAGCTGTGGA
AGCGCTTTGCCTCGCTGCCGATCCGCAATGCCGGGACACTGGGCGGCAACGTCGCAAACGGCTCGCCGATCGGTGACTCG
GCACCCGCGCTCATTGCCATCGGCACGCGCGTCGTCCTGCAGCGTGGCGAAGTCCGCCGCGAGTTGCCGCTCGAAGACCT
CTACCTCGCCTACCAGAAGAACGCGATGGAAGAAGGCGAGTTCGTTGCGGGCCTGCGCATCCCCGCACGTGAGGGCCGCG
ATGCTCTGCGCTTCCGTACGTACAAGCTCTCGAAGCGCTTCGACGAAGACATTTCCGCCGTGTGCGCGGCGTTGGCCATC
GAGCTGGACGGTGACATGGTGCGCAGCGCACGCATCGCTTACGGCGGCATGGCGGCAACGTCCAAGCGCGCGACGGAGAC
GGAAAACGCCATCGTTGGCCAGCCGTGGAACGAAGCGACGGTGCGTGCTGCCATGGCAGCCATGTCGCGTGACTACACCC
CGCTGACCGACATGCGCGCCACCGACAACTACCGCCGCGTATCGGCTGCCAACACGGTGTACCGCTTCTGGCTGGAAACC
CGCACCGATGCGCCGCTCGGGCCCCAACAGATCAATGTGCGCGCAGTCGAATTGAATACCCTCACGGCAGCCTAA

Upstream 100 bases:

>100_bases
GATTTTGGCTTTCCGATGCGGGTTATCACATGGGCCAAATATTGCATTCCTGGCCCGGTGCTATGGTTCCGTTACACACA
CAAACAGGCGTAGAACCCCC

Downstream 100 bases:

>100_bases
GAACATGAACAAGCAAACCGAAGCCTTCCTGCTGGCGGAAGCCGATATTGCTGCCGCCATGCCTGATCAGCGCGGTGCTG
TGGTGGGCATTTCGCGCCCG

Product: xanthine dehydrogenase small subunit

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
METQPIRFFHRGQVRTVTDAPITRTVLQYLREDAHCTGTKEGCAEGDCGACTVVLGELQEDGSVGLKAVNACIQFLPTLD
GKALFTVEDVRGKDGTLHPVQEAMVECHGSQCGFCTPGFVMSLYALYENTGSQAPIPSRQTICDSLTGNLCRCTGYRPII
AAGERMFELPAPAGIDRTQLADTLRKLQRNDTFSYGPVGTENAPRFYAPRTASAFAAIKAAHPNIRILAGSTDVGLWVTK
QFRDLGDILYIGQVADLYALQKRDGWIEIGAAVSLEKAYEFLAADYPELTELWKRFASLPIRNAGTLGGNVANGSPIGDS
APALIAIGTRVVLQRGEVRRELPLEDLYLAYQKNAMEEGEFVAGLRIPAREGRDALRFRTYKLSKRFDEDISAVCAALAI
ELDGDMVRSARIAYGGMAATSKRATETENAIVGQPWNEATVRAAMAAMSRDYTPLTDMRATDNYRRVSAANTVYRFWLET
RTDAPLGPQQINVRAVELNTLTAA

Sequences:

>Translated_504_residues
METQPIRFFHRGQVRTVTDAPITRTVLQYLREDAHCTGTKEGCAEGDCGACTVVLGELQEDGSVGLKAVNACIQFLPTLD
GKALFTVEDVRGKDGTLHPVQEAMVECHGSQCGFCTPGFVMSLYALYENTGSQAPIPSRQTICDSLTGNLCRCTGYRPII
AAGERMFELPAPAGIDRTQLADTLRKLQRNDTFSYGPVGTENAPRFYAPRTASAFAAIKAAHPNIRILAGSTDVGLWVTK
QFRDLGDILYIGQVADLYALQKRDGWIEIGAAVSLEKAYEFLAADYPELTELWKRFASLPIRNAGTLGGNVANGSPIGDS
APALIAIGTRVVLQRGEVRRELPLEDLYLAYQKNAMEEGEFVAGLRIPAREGRDALRFRTYKLSKRFDEDISAVCAALAI
ELDGDMVRSARIAYGGMAATSKRATETENAIVGQPWNEATVRAAMAAMSRDYTPLTDMRATDNYRRVSAANTVYRFWLET
RTDAPLGPQQINVRAVELNTLTAA
>Mature_504_residues
METQPIRFFHRGQVRTVTDAPITRTVLQYLREDAHCTGTKEGCAEGDCGACTVVLGELQEDGSVGLKAVNACIQFLPTLD
GKALFTVEDVRGKDGTLHPVQEAMVECHGSQCGFCTPGFVMSLYALYENTGSQAPIPSRQTICDSLTGNLCRCTGYRPII
AAGERMFELPAPAGIDRTQLADTLRKLQRNDTFSYGPVGTENAPRFYAPRTASAFAAIKAAHPNIRILAGSTDVGLWVTK
QFRDLGDILYIGQVADLYALQKRDGWIEIGAAVSLEKAYEFLAADYPELTELWKRFASLPIRNAGTLGGNVANGSPIGDS
APALIAIGTRVVLQRGEVRRELPLEDLYLAYQKNAMEEGEFVAGLRIPAREGRDALRFRTYKLSKRFDEDISAVCAALAI
ELDGDMVRSARIAYGGMAATSKRATETENAIVGQPWNEATVRAAMAAMSRDYTPLTDMRATDNYRRVSAANTVYRFWLET
RTDAPLGPQQINVRAVELNTLTAA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG4630

COG function: function code F; Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=529, Percent_Identity=27.2211720226843, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI71773480, Length=474, Percent_Identity=26.3713080168776, Blast_Score=147, Evalue=2e-35,
Organism=Escherichia coli, GI1786480, Length=153, Percent_Identity=36.6013071895425, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789231, Length=249, Percent_Identity=25.7028112449799, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789232, Length=121, Percent_Identity=38.8429752066116, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17540638, Length=540, Percent_Identity=30.1851851851852, Blast_Score=227, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI32566215, Length=139, Percent_Identity=47.4820143884892, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17539860, Length=139, Percent_Identity=46.7625899280576, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI17737937, Length=491, Percent_Identity=31.9755600814664, Blast_Score=218, Evalue=7e-57,
Organism=Drosophila melanogaster, GI24647201, Length=500, Percent_Identity=28.6, Blast_Score=174, Evalue=9e-44,
Organism=Drosophila melanogaster, GI24647193, Length=497, Percent_Identity=28.9738430583501, Blast_Score=162, Evalue=6e-40,
Organism=Drosophila melanogaster, GI24647199, Length=501, Percent_Identity=28.1437125748503, Blast_Score=161, Evalue=8e-40,
Organism=Drosophila melanogaster, GI24647197, Length=496, Percent_Identity=28.4274193548387, Blast_Score=158, Evalue=7e-39,
Organism=Drosophila melanogaster, GI24647195, Length=316, Percent_Identity=31.6455696202532, Blast_Score=143, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 55042; Mature: 55042

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS00197 2FE2S_FER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METQPIRFFHRGQVRTVTDAPITRTVLQYLREDAHCTGTKEGCAEGDCGACTVVLGELQE
CCCCCCCCEECCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCC
DGSVGLKAVNACIQFLPTLDGKALFTVEDVRGKDGTLHPVQEAMVECHGSQCGFCTPGFV
CCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHH
MSLYALYENTGSQAPIPSRQTICDSLTGNLCRCTGYRPIIAAGERMFELPAPAGIDRTQL
HHHHHHHHCCCCCCCCCCHHHHHHHHCCCEEEECCCCCHHHCCCCEEECCCCCCCCHHHH
ADTLRKLQRNDTFSYGPVGTENAPRFYAPRTASAFAAIKAAHPNIRILAGSTDVGLWVTK
HHHHHHHHCCCCCCCCCCCCCCCCCEECCCCHHHHHHHEECCCCEEEEECCCCCCEEEHH
QFRDLGDILYIGQVADLYALQKRDGWIEIGAAVSLEKAYEFLAADYPELTELWKRFASLP
HHHHHHHEEEHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHCCC
IRNAGTLGGNVANGSPIGDSAPALIAIGTRVVLQRGEVRRELPLEDLYLAYQKNAMEEGE
CCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHCCCHHHHCCHHHHHHHHHHCCCCCCC
FVAGLRIPAREGRDALRFRTYKLSKRFDEDISAVCAALAIELDGDMVRSARIAYGGMAAT
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHCCCCCCC
SKRATETENAIVGQPWNEATVRAAMAAMSRDYTPLTDMRATDNYRRVSAANTVYRFWLET
CCCCCCCCCCEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHEEEECC
RTDAPLGPQQINVRAVELNTLTAA
CCCCCCCCCEEEEEEEEEECCCCC
>Mature Secondary Structure
METQPIRFFHRGQVRTVTDAPITRTVLQYLREDAHCTGTKEGCAEGDCGACTVVLGELQE
CCCCCCCCEECCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCC
DGSVGLKAVNACIQFLPTLDGKALFTVEDVRGKDGTLHPVQEAMVECHGSQCGFCTPGFV
CCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHH
MSLYALYENTGSQAPIPSRQTICDSLTGNLCRCTGYRPIIAAGERMFELPAPAGIDRTQL
HHHHHHHHCCCCCCCCCCHHHHHHHHCCCEEEECCCCCHHHCCCCEEECCCCCCCCHHHH
ADTLRKLQRNDTFSYGPVGTENAPRFYAPRTASAFAAIKAAHPNIRILAGSTDVGLWVTK
HHHHHHHHCCCCCCCCCCCCCCCCCEECCCCHHHHHHHEECCCCEEEEECCCCCCEEEHH
QFRDLGDILYIGQVADLYALQKRDGWIEIGAAVSLEKAYEFLAADYPELTELWKRFASLP
HHHHHHHEEEHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHCCC
IRNAGTLGGNVANGSPIGDSAPALIAIGTRVVLQRGEVRRELPLEDLYLAYQKNAMEEGE
CCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHCCCHHHHCCHHHHHHHHHHCCCCCCC
FVAGLRIPAREGRDALRFRTYKLSKRFDEDISAVCAALAIELDGDMVRSARIAYGGMAAT
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHCCCCCCC
SKRATETENAIVGQPWNEATVRAAMAAMSRDYTPLTDMRATDNYRRVSAANTVYRFWLET
CCCCCCCCCCEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHEEEECC
RTDAPLGPQQINVRAVELNTLTAA
CCCCCCCCCEEEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]