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The map label for this gene is nuoA

Identifier: 187929293

GI number: 187929293

Start: 2324213

End: 2324572

Strand: Reverse

Name: nuoA

Synonym: Rpic_2214

Alternate gene names: 187929293

Gene position: 2324572-2324213 (Counterclockwise)

Preceding gene: 187929294

Following gene: 187929292

Centisome position: 58.96

GC content: 57.5

Gene sequence:

>360_bases
TTGAACCTCGAAGCCTATTTCCCCGTACTGTTGTTCATCGTTGTCGGTGTTGGCCTCGGCCTTGCTCTGATGACCATCGG
CCGAGTCCTCGGTCCGAACAATCCCGATCCTGACAAGCTCTCGCCGTACGAGTGCGGCTTCGAGGCATTCGAAGACGCGC
GCATGAAGTTCGACGTGCGCTATTACCTCATCGCCATCCTGTTCATTCTGTTCGATCTGGAGACCGCGTTCCTCTTCCCC
TGGGGCGTGGCGCTGCGTGAGATCGGCTGGCCGGGGTTCTTTGCGATGGGCGTGTTTCTTCTCGAGTTTCTCGTGGGCTT
CGTCTACATCTGGAAAAAAGGCGCGCTCGATTGGGAGTGA

Upstream 100 bases:

>100_bases
TCGAGGCGTCGTAAGGCTGCGGACCCGGCGCCTTCGATGGGGCGACAAGGCGCCGCCTGCGGGCAGTGCTGTTGCAACCA
TTCAAAAAGGCGGGCGTCCC

Downstream 100 bases:

>100_bases
TGTGAAATGGCGATCGAAGGCGTACTCAACGAAGGCTTTGTCACGACAACCGCTGACAAGCTGATCAACTGGACCCGTAC
CGGGTCACTCTGGCCGATGA

Product: NADH dehydrogenase subunit A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MNLEAYFPVLLFIVVGVGLGLALMTIGRVLGPNNPDPDKLSPYECGFEAFEDARMKFDVRYYLIAILFILFDLETAFLFP
WGVALREIGWPGFFAMGVFLLEFLVGFVYIWKKGALDWE

Sequences:

>Translated_119_residues
MNLEAYFPVLLFIVVGVGLGLALMTIGRVLGPNNPDPDKLSPYECGFEAFEDARMKFDVRYYLIAILFILFDLETAFLFP
WGVALREIGWPGFFAMGVFLLEFLVGFVYIWKKGALDWE
>Mature_119_residues
MNLEAYFPVLLFIVVGVGLGLALMTIGRVLGPNNPDPDKLSPYECGFEAFEDARMKFDVRYYLIAILFILFDLETAFLFP
WGVALREIGWPGFFAMGVFLLEFLVGFVYIWKKGALDWE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family

Homologues:

Organism=Escherichia coli, GI1788625, Length=108, Percent_Identity=36.1111111111111, Blast_Score=88, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOA_RALPJ (B2U7R1)

Other databases:

- EMBL:   CP001068
- RefSeq:   YP_001899780.1
- GeneID:   6287762
- GenomeReviews:   CP001068_GR
- KEGG:   rpi:Rpic_2214
- HOGENOM:   HBG605540
- OMA:   GRFPIKY
- ProtClustDB:   PRK06602
- GO:   GO:0006810
- HAMAP:   MF_01394
- InterPro:   IPR023043
- InterPro:   IPR000440
- PANTHER:   PTHR11058

Pfam domain/function: PF00507 Oxidored_q4

EC number: =1.6.99.5

Molecular weight: Translated: 13584; Mature: 13584

Theoretical pI: Translated: 4.17; Mature: 4.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x16f80744)-; HASH(0x407fbcbc)-; HASH(0x407fc604)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLEAYFPVLLFIVVGVGLGLALMTIGRVLGPNNPDPDKLSPYECGFEAFEDARMKFDVR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCHHHHHHHHHHHHHH
YYLIAILFILFDLETAFLFPWGVALREIGWPGFFAMGVFLLEFLVGFVYIWKKGALDWE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure
MNLEAYFPVLLFIVVGVGLGLALMTIGRVLGPNNPDPDKLSPYECGFEAFEDARMKFDVR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCHHHHHHHHHHHHHH
YYLIAILFILFDLETAFLFPWGVALREIGWPGFFAMGVFLLEFLVGFVYIWKKGALDWE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA