Click here to switch to the map view.

The map label for this gene is yngJ [H]

Identifier: 187929256

GI number: 187929256

Start: 2289274

End: 2290533

Strand: Direct

Name: yngJ [H]

Synonym: Rpic_2177

Alternate gene names: 187929256

Gene position: 2289274-2290533 (Clockwise)

Preceding gene: 187929255

Following gene: 187929257

Centisome position: 58.07

GC content: 65.4

Gene sequence:

>1260_bases
ATGAATTTCGATTACACGCCCAAGGTCAAGGACATGCAGGCACGCCTGCTCGCATTCTTCGACCAGCACATCTACCCGAA
TGAGCACCGCTTCCACGAAGAAATCGAGGCCAACCGCCGCGCCGGCAATGCGTGGATCCCGACCAAGGTGATCGAAGAAC
TCAAGCCGCTGGCACGCAAGGCCGGGCTGTGGAACCTGTTCCTGCCGCGTTCGCCGCGCGCGCCCGAAGGGCTGTCGAAC
CTCGAATACGCGCCGCTGTGCGAGATCATGGGCCGCGTGCCCTGGGCGCCGGAAGTGTTCAACTGTTCCGCGCCCGACAC
CGGCAACATGGAGACGCTTGAGCGCTATGCGTCGGAAGAACTGAAAGACCGCTGGCTGGAGCCGCTGCTGCGCGGTGAGA
TCCGCTCGGCCTTCCTGATGACCGAACCGGCCGTGGCTTCGTCGGACGCCACCAACATCGAATGCCGCATCGAACGCCAG
GGCGACGAATACGTCATCAACGGCCGCAAGTGGTGGTCGTCGGGCGCCGGCGACCCGCGCTGCGCCGTCTACATCGTCAT
GGGCAAGACCAACCCGGATGCCGGCCGCCACGAGCAGCAATCGATGATCGTGGTGCCAGCCAATGCGCCGGGCATCACGG
TCATGCGCCCGCTGTCGGTGTTCGGTTACGACGATGCGCCGCACGGCCACATGGAAGTCGACCTGAAAGACGTGCGCGTG
CCGGTGGGCAACATCCTCCTGGGTGAAGGCCGCGGTTTCGAGATCGCTCAAGGCCGCCTGGGCCCGGGCCGCATCCACCA
CTGCATGCGCAGCATCGGCGTGGCCGAGCGTGCGCTGGAGCTGATGTGCAAGCGCCTGTCGTCGCGCATCGCATTCGGCA
AGGCCATTGCGCAGCACAGCGTCTGGCACGAACGCATTGCCGAAGCGCGCTGCATGATCGAGCAGGCCCGCCTGCTGACG
CTCAAGGCCGCGTACATGATGGACACCGTCGGCAACAAGGTCGCCAAGGCCGAGATCGCGATGATCAAGGTCGTGGCACC
GAACATCGCCTGCCAGATCGTCGACTGGGCGATCCAGGCACACGGCGGCGGCGGCGTGTCGGGTGATTTCCCGCTGGCTT
CGGCCTACGCCCACCAGCGCACGCTGCGTCTGGCCGACGGCCCGGATGAAGTGCACCGCGCGGCCATCGCCAAGCTGGAA
CTGGCCAAGCATCTGCACCTGAAAGACGTTGTCGACATGCCGGTCACACGCGGCGCCTGA

Upstream 100 bases:

>100_bases
GCAGTGCTCGGCGGACATGTTTGATGCATGGCCGAGCCCGACTGAACTGAGTTGATGGTTGCCCGTTCGGGGCGCTTGTT
CGATGTACTGAGGAGACACC

Downstream 100 bases:

>100_bases
CCTGCGGCACGGCTGTACCGTTCACTCCTTAACCCCGCCTTGAGCGGGGATTTTTTTGCCCGCTGCCCGGCGTCTGCGCG
TTTCTCGGTTCTGTGCTGGA

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MNFDYTPKVKDMQARLLAFFDQHIYPNEHRFHEEIEANRRAGNAWIPTKVIEELKPLARKAGLWNLFLPRSPRAPEGLSN
LEYAPLCEIMGRVPWAPEVFNCSAPDTGNMETLERYASEELKDRWLEPLLRGEIRSAFLMTEPAVASSDATNIECRIERQ
GDEYVINGRKWWSSGAGDPRCAVYIVMGKTNPDAGRHEQQSMIVVPANAPGITVMRPLSVFGYDDAPHGHMEVDLKDVRV
PVGNILLGEGRGFEIAQGRLGPGRIHHCMRSIGVAERALELMCKRLSSRIAFGKAIAQHSVWHERIAEARCMIEQARLLT
LKAAYMMDTVGNKVAKAEIAMIKVVAPNIACQIVDWAIQAHGGGGVSGDFPLASAYAHQRTLRLADGPDEVHRAAIAKLE
LAKHLHLKDVVDMPVTRGA

Sequences:

>Translated_419_residues
MNFDYTPKVKDMQARLLAFFDQHIYPNEHRFHEEIEANRRAGNAWIPTKVIEELKPLARKAGLWNLFLPRSPRAPEGLSN
LEYAPLCEIMGRVPWAPEVFNCSAPDTGNMETLERYASEELKDRWLEPLLRGEIRSAFLMTEPAVASSDATNIECRIERQ
GDEYVINGRKWWSSGAGDPRCAVYIVMGKTNPDAGRHEQQSMIVVPANAPGITVMRPLSVFGYDDAPHGHMEVDLKDVRV
PVGNILLGEGRGFEIAQGRLGPGRIHHCMRSIGVAERALELMCKRLSSRIAFGKAIAQHSVWHERIAEARCMIEQARLLT
LKAAYMMDTVGNKVAKAEIAMIKVVAPNIACQIVDWAIQAHGGGGVSGDFPLASAYAHQRTLRLADGPDEVHRAAIAKLE
LAKHLHLKDVVDMPVTRGA
>Mature_419_residues
MNFDYTPKVKDMQARLLAFFDQHIYPNEHRFHEEIEANRRAGNAWIPTKVIEELKPLARKAGLWNLFLPRSPRAPEGLSN
LEYAPLCEIMGRVPWAPEVFNCSAPDTGNMETLERYASEELKDRWLEPLLRGEIRSAFLMTEPAVASSDATNIECRIERQ
GDEYVINGRKWWSSGAGDPRCAVYIVMGKTNPDAGRHEQQSMIVVPANAPGITVMRPLSVFGYDDAPHGHMEVDLKDVRV
PVGNILLGEGRGFEIAQGRLGPGRIHHCMRSIGVAERALELMCKRLSSRIAFGKAIAQHSVWHERIAEARCMIEQARLLT
LKAAYMMDTVGNKVAKAEIAMIKVVAPNIACQIVDWAIQAHGGGGVSGDFPLASAYAHQRTLRLADGPDEVHRAAIAKLE
LAKHLHLKDVVDMPVTRGA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI38505218, Length=401, Percent_Identity=58.1047381546135, Blast_Score=469, Evalue=1e-132,
Organism=Homo sapiens, GI48976061, Length=404, Percent_Identity=56.1881188118812, Blast_Score=450, Evalue=1e-126,
Organism=Homo sapiens, GI211971008, Length=404, Percent_Identity=56.1881188118812, Blast_Score=449, Evalue=1e-126,
Organism=Homo sapiens, GI187960098, Length=416, Percent_Identity=25.7211538461538, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI4557231, Length=416, Percent_Identity=25.7211538461538, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI21361497, Length=385, Percent_Identity=28.3116883116883, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI4501859, Length=322, Percent_Identity=28.2608695652174, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI4557233, Length=321, Percent_Identity=29.2834890965732, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI7656849, Length=286, Percent_Identity=29.7202797202797, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI226958412, Length=323, Percent_Identity=25.6965944272446, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI226958414, Length=324, Percent_Identity=25.6172839506173, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI76496475, Length=405, Percent_Identity=26.1728395061728, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI4557235, Length=409, Percent_Identity=26.6503667481663, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI4501857, Length=313, Percent_Identity=24.6006389776358, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI87081958, Length=304, Percent_Identity=26.6447368421053, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786223, Length=297, Percent_Identity=22.5589225589226, Blast_Score=75, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17562446, Length=365, Percent_Identity=56.1643835616438, Blast_Score=410, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17569725, Length=408, Percent_Identity=26.7156862745098, Blast_Score=135, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17534899, Length=404, Percent_Identity=26.4851485148515, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17570075, Length=289, Percent_Identity=28.3737024221453, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17533517, Length=294, Percent_Identity=28.9115646258503, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71985184, Length=410, Percent_Identity=25.609756097561, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17506239, Length=284, Percent_Identity=28.5211267605634, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17505929, Length=293, Percent_Identity=26.2798634812287, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17538396, Length=382, Percent_Identity=24.3455497382199, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17508101, Length=338, Percent_Identity=25.4437869822485, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17551932, Length=288, Percent_Identity=25.3472222222222, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71985192, Length=314, Percent_Identity=24.203821656051, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71990804, Length=210, Percent_Identity=27.6190476190476, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71982178, Length=186, Percent_Identity=27.4193548387097, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24660351, Length=283, Percent_Identity=30.3886925795053, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24646207, Length=285, Percent_Identity=30.1754385964912, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI281363737, Length=378, Percent_Identity=26.4550264550265, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24666513, Length=366, Percent_Identity=28.1420765027322, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21356377, Length=367, Percent_Identity=28.3378746594005, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI21355753, Length=354, Percent_Identity=25.1412429378531, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 46588; Mature: 46588

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFDYTPKVKDMQARLLAFFDQHIYPNEHRFHEEIEANRRAGNAWIPTKVIEELKPLARK
CCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
AGLWNLFLPRSPRAPEGLSNLEYAPLCEIMGRVPWAPEVFNCSAPDTGNMETLERYASEE
CCCEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCEECCCCCCCCHHHHHHHHHHH
LKDRWLEPLLRGEIRSAFLMTEPAVASSDATNIECRIERQGDEYVINGRKWWSSGAGDPR
HHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEEECCCEEEECCCEECCCCCCCCC
CAVYIVMGKTNPDAGRHEQQSMIVVPANAPGITVMRPLSVFGYDDAPHGHMEVDLKDVRV
EEEEEEEECCCCCCCCCCCCCEEEEECCCCCEEEECCHHHCCCCCCCCCCEEEEHHHEEC
PVGNILLGEGRGFEIAQGRLGPGRIHHCMRSIGVAERALELMCKRLSSRIAFGKAIAQHS
CCCCEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VWHERIAEARCMIEQARLLTLKAAYMMDTVGNKVAKAEIAMIKVVAPNIACQIVDWAIQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEEEEEECCCHHEEEEEEEEEE
HGGGGVSGDFPLASAYAHQRTLRLADGPDEVHRAAIAKLELAKHLHLKDVVDMPVTRGA
CCCCCCCCCCCHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNFDYTPKVKDMQARLLAFFDQHIYPNEHRFHEEIEANRRAGNAWIPTKVIEELKPLARK
CCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
AGLWNLFLPRSPRAPEGLSNLEYAPLCEIMGRVPWAPEVFNCSAPDTGNMETLERYASEE
CCCEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCEECCCCCCCCHHHHHHHHHHH
LKDRWLEPLLRGEIRSAFLMTEPAVASSDATNIECRIERQGDEYVINGRKWWSSGAGDPR
HHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEEECCCEEEECCCEECCCCCCCCC
CAVYIVMGKTNPDAGRHEQQSMIVVPANAPGITVMRPLSVFGYDDAPHGHMEVDLKDVRV
EEEEEEEECCCCCCCCCCCCCEEEEECCCCCEEEECCHHHCCCCCCCCCCEEEEHHHEEC
PVGNILLGEGRGFEIAQGRLGPGRIHHCMRSIGVAERALELMCKRLSSRIAFGKAIAQHS
CCCCEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VWHERIAEARCMIEQARLLTLKAAYMMDTVGNKVAKAEIAMIKVVAPNIACQIVDWAIQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEEEEEECCCHHEEEEEEEEEE
HGGGGVSGDFPLASAYAHQRTLRLADGPDEVHRAAIAKLELAKHLHLKDVVDMPVTRGA
CCCCCCCCCCCHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]