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The map label for this gene is cocE [H]

Identifier: 187929172

GI number: 187929172

Start: 2204475

End: 2206481

Strand: Direct

Name: cocE [H]

Synonym: Rpic_2093

Alternate gene names: 187929172

Gene position: 2204475-2206481 (Clockwise)

Preceding gene: 187929168

Following gene: 187929173

Centisome position: 55.91

GC content: 66.57

Gene sequence:

>2007_bases
ATGCAAATGGGCACCCCACGTGTGCGGCGCGGCCGCATGCTGATGTCGGCACTGCTGTGCGCGGCGCTTTCGCTCTCGGG
CTGCGGCGGCAATGATGGCTCGACTGTCGCCAACAGCATCCGCGCAGATTCAAACACCACCACGCAGCCAACACCGCCGG
TACAGCCGGCCGCAGTCAACTGGACCACGCTCGGTACGCGCGCCACGCCCGCGCAGCCGGGCACGTCCATCACGAGCAAC
GCTGGCGCCAAGTGGGTCGACTACAACCCGCCCGTGCTCTACGCGGGCGTCGCCCGGCAAGCCACGCAATACATCTCGAT
GCCCGACGGCACGAAGCTCGCCGCATATGTGACGCTGCCCGCCGACGCATCCGGCAACGCCGCAACGGGCTCCTTTCCGA
CGGTGCTCGTGCAAACCTCGTACAACGGCGGCAACGCGCAATACGAAGCCTCGATCGGTGCTGCGCTGGGCGCGGCCGAT
CCGTACATCGTCCAGCACGGCTACGCGACGGTGGTGGTGGACGTGCGCGGCACCGGCCAGTCGCAAGGCACATGGGACGC
CTTCGGCGCCGATGAGCAAAGCGACTATGGCCACGTGGTCGACTGGGTGACGCAACAAGCGTGGAGCAACGGCGCCATCG
GCCTGTACGGCGTGTCGTACCTCGGCATCACGACGGTCATCACGGCGGCGCAGAACCATCCGGCGGTCAAGGCGGCCTTC
CCCATCGTGCCGATTGGCGATGGCTACCGCGACATCGTCTTCACCGGCGGGCAGACCAATCTGACGTTCATCCCGGCGTG
GTTCGGGCTGGTGTCGGTGCTGAGCCTGACCGATCCGACGCTGGTGACAGACCCGTCCATCGGTCTGCCAGCCGTGCTGC
AACATCTGGTGTCTGCGGTCACGACGTTCCAGCTGCCGACCATGTTGCAGGCACTGCTTGGCACACCGGCCACCGCCTAT
GACGGCGCGTTCTGGGCGACGCGCTCGCCACTGGAAAACGACGACAGGATCAGGGTGCCGACCTTCGTGGTGGGCGGCTT
GCACGATCTCTTCCAGCGCAGCGAGCCGCTCACGTACGAGAGCATCAAGACGCAGGCGCCGGCCAAGTTGCTGATCGGCC
CGTGGACGCATCTGCAGGCCGCGTTGGGCAGCGGTTTGCCGGTCGATGGCGTGCCGCCGCTGAACCACATTCAGTTGCAA
TGGTTCGACCAGTACGTCAAAGGCATGAACGTGGGCGCCGATGCGCTGCCCAACGTCACGCAATACGTGACCGGCCTCGG
CCACTACGCTACCGCCACAGACTGGCCGCATCCGCAGGTGCAGGCGCAGCAGCTCTTCCTGCGCGGCGACAAAAGTCTGT
CGACCACCGCGCCGGCCGCCAACGAAGCGTCGAACAAGGTCGCACAGCAGCCGCTGAATGGCGCGTGCTCCATCAGCCTG
TCGCAATGGACGGCCGGTTTGACGGGCTTCATCCCGCTACCGTGCCAGACCGACGACACCCTTGCCGAAGCCGCCGATGT
GAAGTTCGAAACGCCGCCCATGCCGGCCGATGTCTACCTCAACGGGCCGATTGAAGCGGATATGTGGATCTCCACCACCG
CGCTGGACGCCGGCGTCTCGGTACGCATTGACGACGTGGACGCGGCAGGCAACGTCACGCCACTCACCGATGGCCTCCAG
ACGGCCTCGCTGCGCGCGGTGGACGCCAGCCGTTCGCGCACGATGAACGGCCTGTCGATCCAGCCATGGCATCCGTTCAC
CCCAGGCTCCGTTCAGGCGCTCATGCCGGGCCAGGCCGTGATGGTGCCGGTCGAGGTGTTCCCGACCAGCGCGCTCATCG
CCAAGGGCCACAAGCTGCGGGTGGCCGTGGGCGCGAGCAACCTGCCGCAAGGTGTGCCGCCACTACCTACGCTGCTCAAC
TCGCTCGTCGGCGTCCTGACGGTCTATAGCGATGCGGCGCATCCGTCCACGGTGGTCCTGCCCGTGGTACCAGCCACCGC
GCTGTAG

Upstream 100 bases:

>100_bases
TGCTTCGCTTCTGAACCGGAAGCGATCGGCCGCATGCCGCCACCCTCGGCGCGCTGGCCATTCCCCCCACACAACAAAAG
CATTCAAGAGGAGACACCCC

Downstream 100 bases:

>100_bases
CGACACCCCGCTTCGTGGCAATCGTACGGCCCGCTTCGGCGGGCCGTTTTCTTTAGACACCCGACACCACAAAAATAGGT
AGCCAGCTAAATACATAGGT

Product: peptidase S15

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 668; Mature: 668

Protein sequence:

>668_residues
MQMGTPRVRRGRMLMSALLCAALSLSGCGGNDGSTVANSIRADSNTTTQPTPPVQPAAVNWTTLGTRATPAQPGTSITSN
AGAKWVDYNPPVLYAGVARQATQYISMPDGTKLAAYVTLPADASGNAATGSFPTVLVQTSYNGGNAQYEASIGAALGAAD
PYIVQHGYATVVVDVRGTGQSQGTWDAFGADEQSDYGHVVDWVTQQAWSNGAIGLYGVSYLGITTVITAAQNHPAVKAAF
PIVPIGDGYRDIVFTGGQTNLTFIPAWFGLVSVLSLTDPTLVTDPSIGLPAVLQHLVSAVTTFQLPTMLQALLGTPATAY
DGAFWATRSPLENDDRIRVPTFVVGGLHDLFQRSEPLTYESIKTQAPAKLLIGPWTHLQAALGSGLPVDGVPPLNHIQLQ
WFDQYVKGMNVGADALPNVTQYVTGLGHYATATDWPHPQVQAQQLFLRGDKSLSTTAPAANEASNKVAQQPLNGACSISL
SQWTAGLTGFIPLPCQTDDTLAEAADVKFETPPMPADVYLNGPIEADMWISTTALDAGVSVRIDDVDAAGNVTPLTDGLQ
TASLRAVDASRSRTMNGLSIQPWHPFTPGSVQALMPGQAVMVPVEVFPTSALIAKGHKLRVAVGASNLPQGVPPLPTLLN
SLVGVLTVYSDAAHPSTVVLPVVPATAL

Sequences:

>Translated_668_residues
MQMGTPRVRRGRMLMSALLCAALSLSGCGGNDGSTVANSIRADSNTTTQPTPPVQPAAVNWTTLGTRATPAQPGTSITSN
AGAKWVDYNPPVLYAGVARQATQYISMPDGTKLAAYVTLPADASGNAATGSFPTVLVQTSYNGGNAQYEASIGAALGAAD
PYIVQHGYATVVVDVRGTGQSQGTWDAFGADEQSDYGHVVDWVTQQAWSNGAIGLYGVSYLGITTVITAAQNHPAVKAAF
PIVPIGDGYRDIVFTGGQTNLTFIPAWFGLVSVLSLTDPTLVTDPSIGLPAVLQHLVSAVTTFQLPTMLQALLGTPATAY
DGAFWATRSPLENDDRIRVPTFVVGGLHDLFQRSEPLTYESIKTQAPAKLLIGPWTHLQAALGSGLPVDGVPPLNHIQLQ
WFDQYVKGMNVGADALPNVTQYVTGLGHYATATDWPHPQVQAQQLFLRGDKSLSTTAPAANEASNKVAQQPLNGACSISL
SQWTAGLTGFIPLPCQTDDTLAEAADVKFETPPMPADVYLNGPIEADMWISTTALDAGVSVRIDDVDAAGNVTPLTDGLQ
TASLRAVDASRSRTMNGLSIQPWHPFTPGSVQALMPGQAVMVPVEVFPTSALIAKGHKLRVAVGASNLPQGVPPLPTLLN
SLVGVLTVYSDAAHPSTVVLPVVPATAL
>Mature_668_residues
MQMGTPRVRRGRMLMSALLCAALSLSGCGGNDGSTVANSIRADSNTTTQPTPPVQPAAVNWTTLGTRATPAQPGTSITSN
AGAKWVDYNPPVLYAGVARQATQYISMPDGTKLAAYVTLPADASGNAATGSFPTVLVQTSYNGGNAQYEASIGAALGAAD
PYIVQHGYATVVVDVRGTGQSQGTWDAFGADEQSDYGHVVDWVTQQAWSNGAIGLYGVSYLGITTVITAAQNHPAVKAAF
PIVPIGDGYRDIVFTGGQTNLTFIPAWFGLVSVLSLTDPTLVTDPSIGLPAVLQHLVSAVTTFQLPTMLQALLGTPATAY
DGAFWATRSPLENDDRIRVPTFVVGGLHDLFQRSEPLTYESIKTQAPAKLLIGPWTHLQAALGSGLPVDGVPPLNHIQLQ
WFDQYVKGMNVGADALPNVTQYVTGLGHYATATDWPHPQVQAQQLFLRGDKSLSTTAPAANEASNKVAQQPLNGACSISL
SQWTAGLTGFIPLPCQTDDTLAEAADVKFETPPMPADVYLNGPIEADMWISTTALDAGVSVRIDDVDAAGNVTPLTDGLQ
TASLRAVDASRSRTMNGLSIQPWHPFTPGSVQALMPGQAVMVPVEVFPTSALIAKGHKLRVAVGASNLPQGVPPLPTLLN
SLVGVLTVYSDAAHPSTVVLPVVPATAL

Specific function: Hydrolyzes cocaine to benzoate and ecgonine methyl ester, endowing the bacteria with the ability to utilize cocaine as a sole source of carbon and energy for growth, as this bacterium lives in the rhizosphere of coca plants [H]

COG id: COG2936

COG function: function code R; Predicted acyl esterases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alpha/beta hydrolase family. Carboxylesterase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005674
- InterPro:   IPR008979
- InterPro:   IPR013736
- InterPro:   IPR000383 [H]

Pfam domain/function: PF02129 Peptidase_S15; PF08530 PepX_C [H]

EC number: NA

Molecular weight: Translated: 69874; Mature: 69874

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMGTPRVRRGRMLMSALLCAALSLSGCGGNDGSTVANSIRADSNTTTQPTPPVQPAAVN
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEE
WTTLGTRATPAQPGTSITSNAGAKWVDYNPPVLYAGVARQATQYISMPDGTKLAAYVTLP
EEECCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEHHHHHHHHHCCCCCCCEEEEEEEEC
ADASGNAATGSFPTVLVQTSYNGGNAQYEASIGAALGAADPYIVQHGYATVVVDVRGTGQ
CCCCCCCCCCCCCEEEEEEECCCCCEEEEEEHHHHHCCCCCEEEECCCEEEEEEEECCCC
SQGTWDAFGADEQSDYGHVVDWVTQQAWSNGAIGLYGVSYLGITTVITAAQNHPAVKAAF
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHEECCCCCCEEEEC
PIVPIGDGYRDIVFTGGQTNLTFIPAWFGLVSVLSLTDPTLVTDPSIGLPAVLQHLVSAV
CEEECCCCCEEEEEECCCCCEEEHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHH
TTFQLPTMLQALLGTPATAYDGAFWATRSPLENDDRIRVPTFVVGGLHDLFQRSEPLTYE
HHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCEEECEEEECCHHHHHHCCCCCCHH
SIKTQAPAKLLIGPWTHLQAALGSGLPVDGVPPLNHIQLQWFDQYVKGMNVGADALPNVT
HHHCCCCCEEEECCHHHHHHHHCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCCHHCCCHH
QYVTGLGHYATATDWPHPQVQAQQLFLRGDKSLSTTAPAANEASNKVAQQPLNGACSISL
HHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEH
SQWTAGLTGFIPLPCQTDDTLAEAADVKFETPPMPADVYLNGPIEADMWISTTALDAGVS
HHHCCCCCCEEECCCCCCHHHHHHHCCEECCCCCCCEEEECCCCCCCEEEEEEEECCCCE
VRIDDVDAAGNVTPLTDGLQTASLRAVDASRSRTMNGLSIQPWHPFTPGSVQALMPGQAV
EEEECCCCCCCCCCCCCCCCHHEEEEECCHHHHCCCCCEECCCCCCCCCCCEEECCCCEE
MVPVEVFPTSALIAKGHKLRVAVGASNLPQGVPPLPTLLNSLVGVLTVYSDAAHPSTVVL
EEEEEECCCHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEE
PVVPATAL
ECCCCCCC
>Mature Secondary Structure
MQMGTPRVRRGRMLMSALLCAALSLSGCGGNDGSTVANSIRADSNTTTQPTPPVQPAAVN
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEE
WTTLGTRATPAQPGTSITSNAGAKWVDYNPPVLYAGVARQATQYISMPDGTKLAAYVTLP
EEECCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEHHHHHHHHHCCCCCCCEEEEEEEEC
ADASGNAATGSFPTVLVQTSYNGGNAQYEASIGAALGAADPYIVQHGYATVVVDVRGTGQ
CCCCCCCCCCCCCEEEEEEECCCCCEEEEEEHHHHHCCCCCEEEECCCEEEEEEEECCCC
SQGTWDAFGADEQSDYGHVVDWVTQQAWSNGAIGLYGVSYLGITTVITAAQNHPAVKAAF
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHEECCCCCCEEEEC
PIVPIGDGYRDIVFTGGQTNLTFIPAWFGLVSVLSLTDPTLVTDPSIGLPAVLQHLVSAV
CEEECCCCCEEEEEECCCCCEEEHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHH
TTFQLPTMLQALLGTPATAYDGAFWATRSPLENDDRIRVPTFVVGGLHDLFQRSEPLTYE
HHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCEEECEEEECCHHHHHHCCCCCCHH
SIKTQAPAKLLIGPWTHLQAALGSGLPVDGVPPLNHIQLQWFDQYVKGMNVGADALPNVT
HHHCCCCCEEEECCHHHHHHHHCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCCHHCCCHH
QYVTGLGHYATATDWPHPQVQAQQLFLRGDKSLSTTAPAANEASNKVAQQPLNGACSISL
HHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEH
SQWTAGLTGFIPLPCQTDDTLAEAADVKFETPPMPADVYLNGPIEADMWISTTALDAGVS
HHHCCCCCCEEECCCCCCHHHHHHHCCEECCCCCCCEEEECCCCCCCEEEEEEEECCCCE
VRIDDVDAAGNVTPLTDGLQTASLRAVDASRSRTMNGLSIQPWHPFTPGSVQALMPGQAV
EEEECCCCCCCCCCCCCCCCHHEEEEECCHHHHCCCCCEECCCCCCCCCCCEEECCCCEE
MVPVEVFPTSALIAKGHKLRVAVGASNLPQGVPPLPTLLNSLVGVLTVYSDAAHPSTVVL
EEEEEECCCHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEE
PVVPATAL
ECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10698749; 11742345; 12369817 [H]