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The map label for this gene is dppB [H]

Identifier: 187929162

GI number: 187929162

Start: 2192458

End: 2193441

Strand: Direct

Name: dppB [H]

Synonym: Rpic_2083

Alternate gene names: 187929162

Gene position: 2192458-2193441 (Clockwise)

Preceding gene: 187929161

Following gene: 187929163

Centisome position: 55.61

GC content: 65.55

Gene sequence:

>984_bases
ATGACAGGTTGGCTCATCCGCCGCATCGGCCAGGCGCTGCTGGTCGTGCTGGTGATGACGGTAATCGTCTTCATCGGCCT
GCACGCCATCGGCAACCCGGTCGACATCCTGATCGGCCAGGACGTCGACCAGATCGACCGCGCGCGCATCATTGCCGAAC
TGGGCCTCGACAAACCGCTGTGGGAGCAGTACCTCGCCTTCCTGAACGGCGCGCTGCATGGCAATCTCGGCAAGAGCTTC
GTCTACAACGAACCGGCCATCCAGCTGATCCTGCAACGCCTGCCGGCCACGCTGGAGCTGGCGTTTTCGGCGCTGATCAT
CGCGGTGGTGATCGGCGTGCCGCTTGGGCTGTTCGCGGGGCTGTATCCGCGCCATCCGGTATCGCGCCTGCTCATGACGG
GCAGCGTGGTGGGATTCTCATTGCCGACGTTCTGGGTGGGCCTGATGCTGATCATGGCGTTCAGCGTGAGCCTCGGCTGG
CTGCCCGCCAGCGGGCGCGGCGAAACCGCACGCCTGTTCGGCGTCGAATGGTCGTGGCTGACGGTCGATGGGCTGCGGCA
CCTCGTGCTGCCGGCGGTCAACCTGTCGCTGTTCAAGCTCTCGCTGGTGCTGCGGCTGACTTCTGCCGGCGTGCGCGAGG
TGGTGCCGCTGGATTTCGTGAAGTTCGCGCGTGCCAAGGGCCTGTCGCCGCTGCGCGTGGTGCTGGCGCACGTGCTGCGC
AACACGCTGATCCCGCTGGTGACGGTGCTGGGCCTGGAGCTGGGCTCGACCATCGCCTTTGCGGTGGTGACGGAAAGCAT
CTTTGCGTGGCCCGGCGCGGGCAAGCTCATTCTCGATAGCATCAACTCGCTGGACCGGCCGGTCATCGTGTCGTACCTCA
TCGTTGTGGTGTGCCTGTTCGTGTCGCTCAACCTGATCGTCGACATCCTGTATCGGCTGCTGGACCCGCGCGTGCGTGCG
GCGGACAGCGCGGAGGCTGCATGA

Upstream 100 bases:

>100_bases
TCCAGGCCTACGCCGAGCCGGAAATCTTTGGCGATGAATGGACCCCAGCCCCACCGCCCGGCGTGGAAGCGAATGCCACT
TCCAGCCAGGAGGCTGCCCG

Downstream 100 bases:

>100_bases
TGAATACAACTCCGCAACCCACCACCGCAGCCGCGGTTGCCGCCCCGCGCAAGCAATCGCCGTGGCGCCGCGTGGTGTCC
GATTTTCTGGCATCCCAGAC

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MTGWLIRRIGQALLVVLVMTVIVFIGLHAIGNPVDILIGQDVDQIDRARIIAELGLDKPLWEQYLAFLNGALHGNLGKSF
VYNEPAIQLILQRLPATLELAFSALIIAVVIGVPLGLFAGLYPRHPVSRLLMTGSVVGFSLPTFWVGLMLIMAFSVSLGW
LPASGRGETARLFGVEWSWLTVDGLRHLVLPAVNLSLFKLSLVLRLTSAGVREVVPLDFVKFARAKGLSPLRVVLAHVLR
NTLIPLVTVLGLELGSTIAFAVVTESIFAWPGAGKLILDSINSLDRPVIVSYLIVVVCLFVSLNLIVDILYRLLDPRVRA
ADSAEAA

Sequences:

>Translated_327_residues
MTGWLIRRIGQALLVVLVMTVIVFIGLHAIGNPVDILIGQDVDQIDRARIIAELGLDKPLWEQYLAFLNGALHGNLGKSF
VYNEPAIQLILQRLPATLELAFSALIIAVVIGVPLGLFAGLYPRHPVSRLLMTGSVVGFSLPTFWVGLMLIMAFSVSLGW
LPASGRGETARLFGVEWSWLTVDGLRHLVLPAVNLSLFKLSLVLRLTSAGVREVVPLDFVKFARAKGLSPLRVVLAHVLR
NTLIPLVTVLGLELGSTIAFAVVTESIFAWPGAGKLILDSINSLDRPVIVSYLIVVVCLFVSLNLIVDILYRLLDPRVRA
ADSAEAA
>Mature_326_residues
TGWLIRRIGQALLVVLVMTVIVFIGLHAIGNPVDILIGQDVDQIDRARIIAELGLDKPLWEQYLAFLNGALHGNLGKSFV
YNEPAIQLILQRLPATLELAFSALIIAVVIGVPLGLFAGLYPRHPVSRLLMTGSVVGFSLPTFWVGLMLIMAFSVSLGWL
PASGRGETARLFGVEWSWLTVDGLRHLVLPAVNLSLFKLSLVLRLTSAGVREVVPLDFVKFARAKGLSPLRVVLAHVLRN
TLIPLVTVLGLELGSTIAFAVVTESIFAWPGAGKLILDSINSLDRPVIVSYLIVVVCLFVSLNLIVDILYRLLDPRVRAA
DSAEAA

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=339, Percent_Identity=35.693215339233, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1787053, Length=320, Percent_Identity=33.75, Blast_Score=194, Evalue=7e-51,
Organism=Escherichia coli, GI1789888, Length=330, Percent_Identity=35.7575757575758, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1787761, Length=343, Percent_Identity=35.8600583090379, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1787550, Length=272, Percent_Identity=31.6176470588235, Blast_Score=154, Evalue=9e-39,
Organism=Escherichia coli, GI1787497, Length=322, Percent_Identity=29.8136645962733, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1788504, Length=285, Percent_Identity=25.9649122807018, Blast_Score=91, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35518; Mature: 35387

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGWLIRRIGQALLVVLVMTVIVFIGLHAIGNPVDILIGQDVDQIDRARIIAELGLDKPL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCHH
WEQYLAFLNGALHGNLGKSFVYNEPAIQLILQRLPATLELAFSALIIAVVIGVPLGLFAG
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
LYPRHPVSRLLMTGSVVGFSLPTFWVGLMLIMAFSVSLGWLPASGRGETARLFGVEWSWL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECEEEEE
TVDGLRHLVLPAVNLSLFKLSLVLRLTSAGVREVVPLDFVKFARAKGLSPLRVVLAHVLR
EHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
NTLIPLVTVLGLELGSTIAFAVVTESIFAWPGAGKLILDSINSLDRPVIVSYLIVVVCLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
VSLNLIVDILYRLLDPRVRAADSAEAA
HHHHHHHHHHHHHHCCHHHCCCCCCCC
>Mature Secondary Structure 
TGWLIRRIGQALLVVLVMTVIVFIGLHAIGNPVDILIGQDVDQIDRARIIAELGLDKPL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCHH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HHHHHHHHHHHHHHCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]