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The map label for this gene is lpsI [H]

Identifier: 187929063

GI number: 187929063

Start: 2092607

End: 2093308

Strand: Reverse

Name: lpsI [H]

Synonym: Rpic_1983

Alternate gene names: 187929063

Gene position: 2093308-2092607 (Counterclockwise)

Preceding gene: 187929065

Following gene: 187929062

Centisome position: 53.1

GC content: 61.97

Gene sequence:

>702_bases
ATGAACAAAATCTTCGCCAGCGCCAGCGAGGCGCTCGCGGGCGTCGTCAGGGACGGCCAGACCATCGCCGTGGGCGGCTT
CGGCCTGTGCGGTATTCCGGAAGCGCTGATTGCCGCGCTGCGCGATTCGGGCGTCAAGAATCTCACTTGCATTTCCAACA
ATGCCGGCGTCGATGGTTTCGGCCTGGGCTTGCTGCTGGAAACCCGCCAGATCAAAAAGATGATTTCGTCCTACGTGGGC
GAAAACAAGGAGTTCGAGCGCCAGTATCTGGCCGGTGAACTCGAGTTGGAATTCACCCCGCAAGGCACGCTGGCCGAAAA
GCTGCGCGCTGGCGGCGCCGGCATCCCGGCGTTCTTCACCAAGACCGGTGTCGGCACGCTTGTCGCCGAAGGCAAGGAGC
TGCGCGAGTTTGACGGCGAGACGTACGTCATGGAGCGCTCGCTGGTGCCCGACGTGGCGCTGGTGAAAGCCCAGGTGGCT
GACAAGTCCGGCAACCTGCGTTTCAACCTGACCGCACGCAACTTCAATCCGGCTGCGGCAACGGCCGGCAAGATCTGCAT
CGTTGAGGTCGAAGAGATCGTCGAGGTGGGCGAGCTTGCACCCGACGACATCCATCTGCCCGGCATCTATGTGCACCGCA
TCGTGCTCAATGCCACGCCCGAGAAGCGCATCGAGAAGCGCACCATCCGAGTAGCCAACTAA

Upstream 100 bases:

>100_bases
TGTATCGTTACTATTTTCCGGCGCTGCACCGCACAAACCCCAAGTGTGCGTGCGGTCAAAACCGAGCCGGATTCGTTGGA
CCACCAAGGAAGGAGCACGC

Downstream 100 bases:

>100_bases
GGAGACCGACATGGCCTGGACACAAGACCAAATGGCGGCGCGCGCTGCCCAGGAGTTGCAAGACGGTTTCTACGTCAACC
TCGGCATCGGTATCCCGACG

Product: 3-oxoacid CoA-transferase subunit A

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MNKIFASASEALAGVVRDGQTIAVGGFGLCGIPEALIAALRDSGVKNLTCISNNAGVDGFGLGLLLETRQIKKMISSYVG
ENKEFERQYLAGELELEFTPQGTLAEKLRAGGAGIPAFFTKTGVGTLVAEGKELREFDGETYVMERSLVPDVALVKAQVA
DKSGNLRFNLTARNFNPAAATAGKICIVEVEEIVEVGELAPDDIHLPGIYVHRIVLNATPEKRIEKRTIRVAN

Sequences:

>Translated_233_residues
MNKIFASASEALAGVVRDGQTIAVGGFGLCGIPEALIAALRDSGVKNLTCISNNAGVDGFGLGLLLETRQIKKMISSYVG
ENKEFERQYLAGELELEFTPQGTLAEKLRAGGAGIPAFFTKTGVGTLVAEGKELREFDGETYVMERSLVPDVALVKAQVA
DKSGNLRFNLTARNFNPAAATAGKICIVEVEEIVEVGELAPDDIHLPGIYVHRIVLNATPEKRIEKRTIRVAN
>Mature_233_residues
MNKIFASASEALAGVVRDGQTIAVGGFGLCGIPEALIAALRDSGVKNLTCISNNAGVDGFGLGLLLETRQIKKMISSYVG
ENKEFERQYLAGELELEFTPQGTLAEKLRAGGAGIPAFFTKTGVGTLVAEGKELREFDGETYVMERSLVPDVALVKAQVA
DKSGNLRFNLTARNFNPAAATAGKICIVEVEEIVEVGELAPDDIHLPGIYVHRIVLNATPEKRIEKRTIRVAN

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=247, Percent_Identity=55.8704453441296, Blast_Score=277, Evalue=7e-75,
Organism=Homo sapiens, GI11545841, Length=245, Percent_Identity=52.6530612244898, Blast_Score=232, Evalue=2e-61,
Organism=Escherichia coli, GI1788551, Length=205, Percent_Identity=45.8536585365854, Blast_Score=190, Evalue=5e-50,
Organism=Escherichia coli, GI1787985, Length=239, Percent_Identity=27.1966527196653, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17531517, Length=244, Percent_Identity=56.9672131147541, Blast_Score=269, Evalue=8e-73,
Organism=Drosophila melanogaster, GI24655794, Length=245, Percent_Identity=54.6938775510204, Blast_Score=259, Evalue=2e-69,
Organism=Drosophila melanogaster, GI21358325, Length=245, Percent_Identity=54.6938775510204, Blast_Score=258, Evalue=2e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 24932; Mature: 24932

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKIFASASEALAGVVRDGQTIAVGGFGLCGIPEALIAALRDSGVKNLTCISNNAGVDGF
CCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCC
GLGLLLETRQIKKMISSYVGENKEFERQYLAGELELEFTPQGTLAEKLRAGGAGIPAFFT
CHHHEEHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCCCHHHHHHHCCCCCCCHHHH
KTGVGTLVAEGKELREFDGETYVMERSLVPDVALVKAQVADKSGNLRFNLTARNFNPAAA
HCCCHHHHHCCHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCHH
TAGKICIVEVEEIVEVGELAPDDIHLPGIYVHRIVLNATPEKRIEKRTIRVAN
CCCCEEEEEHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHEEECC
>Mature Secondary Structure
MNKIFASASEALAGVVRDGQTIAVGGFGLCGIPEALIAALRDSGVKNLTCISNNAGVDGF
CCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCC
GLGLLLETRQIKKMISSYVGENKEFERQYLAGELELEFTPQGTLAEKLRAGGAGIPAFFT
CHHHEEHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCCCHHHHHHHCCCCCCCHHHH
KTGVGTLVAEGKELREFDGETYVMERSLVPDVALVKAQVADKSGNLRFNLTARNFNPAAA
HCCCHHHHHCCHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCHH
TAGKICIVEVEEIVEVGELAPDDIHLPGIYVHRIVLNATPEKRIEKRTIRVAN
CCCCEEEEEHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134; 11589581 [H]