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The map label for this gene is hpcR [H]

Identifier: 187929033

GI number: 187929033

Start: 2064589

End: 2065053

Strand: Direct

Name: hpcR [H]

Synonym: Rpic_1953

Alternate gene names: 187929033

Gene position: 2064589-2065053 (Clockwise)

Preceding gene: 187929032

Following gene: 187929045

Centisome position: 52.37

GC content: 64.3

Gene sequence:

>465_bases
ATGGCTTCCGCCTTCAAGCACCGCAATCTTCCGCATCTCCTGCTGCGCGCGCGTGAGACCTTCATGGCGCGCTTTCGGCC
GATCCTGCGCGAGCATGGCATCACCGAACAGCAATGGCGCGTGTTGCGTACGCTCAACGATACCGGCGACATGGAGCCCA
ACCAACTCGCCGATGCATGCCTGATCCTGAGCCCAAGCCTGACGCGCATGCTGGCGGCGATGGAACAATCCGAGATGATC
GTGCGGACGAAGTCGTCGGTGGACCAGCGCCGGCAGGTGATTTCACTCACGCCTAAGAGCCGCCAGTTCCTGGCCGACGT
GGAACCGCAGGTGGATGCCGAGTACGCGCGCATTGAGGCGCAGCTGGGCCGCGCGCGGCTGGACGCGCTCTACGCCGCCA
TCGATGAGTCGATCCACGTCATGGAAACGCGCACGCCGATGGGGCGCTTCACTGGCGACGCGTAA

Upstream 100 bases:

>100_bases
CGAGTCGTGCCATATCGACCGCGTGCCACGCACGTGGGAGCAGCCTTCGGACCACACACCCGTGGTCGCCGCCCTGCGCC
GCGCATAAGGAGTGCCCGGC

Downstream 100 bases:

>100_bases
CACCCGTCAATACACGCTGCCGGCCGGCTGCGGCTTGGCACCGCCCTCTTCCTTGAATGCCTGCGCCAGCTGTTCGGCGC
TGCGCGCCAGCAGGGTGACA

Product: MarR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MASAFKHRNLPHLLLRARETFMARFRPILREHGITEQQWRVLRTLNDTGDMEPNQLADACLILSPSLTRMLAAMEQSEMI
VRTKSSVDQRRQVISLTPKSRQFLADVEPQVDAEYARIEAQLGRARLDALYAAIDESIHVMETRTPMGRFTGDA

Sequences:

>Translated_154_residues
MASAFKHRNLPHLLLRARETFMARFRPILREHGITEQQWRVLRTLNDTGDMEPNQLADACLILSPSLTRMLAAMEQSEMI
VRTKSSVDQRRQVISLTPKSRQFLADVEPQVDAEYARIEAQLGRARLDALYAAIDESIHVMETRTPMGRFTGDA
>Mature_153_residues
ASAFKHRNLPHLLLRARETFMARFRPILREHGITEQQWRVLRTLNDTGDMEPNQLADACLILSPSLTRMLAAMEQSEMIV
RTKSSVDQRRQVISLTPKSRQFLADVEPQVDAEYARIEAQLGRARLDALYAAIDESIHVMETRTPMGRFTGDA

Specific function: Repressor for the homoprotocatechuate catabolic pathway hpc operon [H]

COG id: COG1846

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012712
- InterPro:   IPR000835
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 17607; Mature: 17475

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASAFKHRNLPHLLLRARETFMARFRPILREHGITEQQWRVLRTLNDTGDMEPNQLADAC
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHH
LILSPSLTRMLAAMEQSEMIVRTKSSVDQRRQVISLTPKSRQFLADVEPQVDAEYARIEA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHH
QLGRARLDALYAAIDESIHVMETRTPMGRFTGDA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
ASAFKHRNLPHLLLRARETFMARFRPILREHGITEQQWRVLRTLNDTGDMEPNQLADAC
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHH
LILSPSLTRMLAAMEQSEMIVRTKSSVDQRRQVISLTPKSRQFLADVEPQVDAEYARIEA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHH
QLGRARLDALYAAIDESIHVMETRTPMGRFTGDA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8384293; 8550403 [H]