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The map label for this gene is lolC [H]

Identifier: 187928746

GI number: 187928746

Start: 1746557

End: 1748164

Strand: Direct

Name: lolC [H]

Synonym: Rpic_1663

Alternate gene names: 187928746

Gene position: 1746557-1748164 (Clockwise)

Preceding gene: 187928745

Following gene: 187928748

Centisome position: 44.3

GC content: 64.86

Gene sequence:

>1608_bases
ATGATGCTGCTGCCACTCGCCGTGCGCAATGTGCTGCGCAACCGCAGGCGTTCCGCCATCACCATCTCGTCGATCGCCAT
CGGCCTAGCGGCGATGATCTTCAACTGGGGATTCACCGCTGGCATGAACCGCGAGATGGTCGAGAACACCACGCGGTATT
TCGCCGGCGATGCGCAGGTGCATCTCAAGGGCTACCACGACGATCCGATCCTTGATCTCGCCATGCCAGACTCGGCCCCC
ATCCTGCATGCCGTGCGCAACGAGGCTGGGGTGGCAGCCGCCAGCATCCGCCTGGAAACCAAAGCGCTGGCCAGCCGGGG
CGACAAGTCGCGCGGCCTCATGCTCGTCGGCGTCGAGCCGGCAGACGAGGCGCAGGTGACGATGCTCTCGGACGCCATCG
TGGCCGGGCAGCCGCTGACGACCGGCGCGCCCGGCGTGCTGATCGGGGAGATGCTTGCTGAAGCGCTCGCGGTGCGGCCC
GGGCAGAACATCGTGTTCGTGGGGCAGGGCTACGACGGCTCGATATCGAGCGGAAAGTATCCGGTGCGCGGCATCTTCCG
CAGCAAGATCGACGATCTCGACGGCTACGTCGCCGTGATGCCGCTGCCTGTTGTGCGGGAGTTTCTCTCCGCGCCCGGTG
GCGCCACCGCCATCGCCCTGCGGCTGCGCGAGCGCTCGCGCCTGGAGCCGGTCAGCGCGGGGCTCGCCGAGCGCCTGGGA
GATCGTTACGAAGTCGTGGGGTGGCCACGGCTGCTACCGATGGTAGCGGTCAGTTCGCGCTTTCACGAGGTCACGACCTA
CGTGGTGCTGTTGGTGTTCTTCGTGGTGGTCGTCTTCGCGGTGGCGAATCCTGTGCTGATGTCCGTGATGGAGCGCACGC
GCGAATTCGGCATCATGCTTGCCGTCGGCATGAGCCGCACGCGCGTGCTTCGGCTGGTCCTGTATGAATCGATCCTTCTG
GGCATCGTTGGCCTGATCGTCGGCAACGCCGTCGGCTGGACAGTGACGGCGTATTTCGCGCGCGCGGGTATCCATCTGCA
CGGTTTTGAAGCCGGGCTGCGCACGATGCCCGGGCTGTCCGACGTCGTCTATCCGGTGGTGAGCGCCGAGCGTGGCGTCG
TGCTGTCAGTGGCGGTCTTCGTCATTGCCGGGCTGGCGGCACTGTATCCCGCTGCCAAGGCCGTGCAGTTGCGGCCCATC
GAGGCGATTCGCGGGCTACCCGCTGCCATGCGGGTGTCGTCACGAAACACGGGCGATTCCCGCTTGCCGGTGTTCGTGCT
GCTCGCACTGCGCAACCTGCTGCGCAATCCACGCCGCACGGCCCTCATGGCCGCAGGCGCTGCCTTCGGCATCGTGGGCT
TTGTCTTCATCCTGGGGTTTTTCGACGGATTCTTCGACCAGACGATCGAGAACTCCACGCGTTATCTGACGGGGCACATC
CAGGTCGAACGCAAGGGCTTTCGCAAGGATTATGCCCCCGAGCTTGCCATCGACGATGCCGTCTCGCTGCTGCAAGCCGT
CCGGGGCACGCCTGGCGTGATTGTCGGCATAGCGAAGAAAATTAGAAAAAGCGCCGACCTGACTGGCGAGAATAGCGAAG
TAAGTTAG

Upstream 100 bases:

>100_bases
CGTTCGTGTTCTCCACCCACGACCCGATGGTGGTCGAACGCGCGCGGCGGGTCATTCGCCTGCGTGACGGCCGGATCGAA
GCCGATGAGCGCCGACCGCC

Downstream 100 bases:

>100_bases
AAAAAATAGCGAAGTAGGCTGGAGCATGAAAGAGGCGCGCGCGAGTGTCCCGTCCCCGGGGCGCCAGCCTGCCCAGCCAT
GCAACCAGTGCGGTGCGAGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 535; Mature: 535

Protein sequence:

>535_residues
MMLLPLAVRNVLRNRRRSAITISSIAIGLAAMIFNWGFTAGMNREMVENTTRYFAGDAQVHLKGYHDDPILDLAMPDSAP
ILHAVRNEAGVAAASIRLETKALASRGDKSRGLMLVGVEPADEAQVTMLSDAIVAGQPLTTGAPGVLIGEMLAEALAVRP
GQNIVFVGQGYDGSISSGKYPVRGIFRSKIDDLDGYVAVMPLPVVREFLSAPGGATAIALRLRERSRLEPVSAGLAERLG
DRYEVVGWPRLLPMVAVSSRFHEVTTYVVLLVFFVVVVFAVANPVLMSVMERTREFGIMLAVGMSRTRVLRLVLYESILL
GIVGLIVGNAVGWTVTAYFARAGIHLHGFEAGLRTMPGLSDVVYPVVSAERGVVLSVAVFVIAGLAALYPAAKAVQLRPI
EAIRGLPAAMRVSSRNTGDSRLPVFVLLALRNLLRNPRRTALMAAGAAFGIVGFVFILGFFDGFFDQTIENSTRYLTGHI
QVERKGFRKDYAPELAIDDAVSLLQAVRGTPGVIVGIAKKIRKSADLTGENSEVS

Sequences:

>Translated_535_residues
MMLLPLAVRNVLRNRRRSAITISSIAIGLAAMIFNWGFTAGMNREMVENTTRYFAGDAQVHLKGYHDDPILDLAMPDSAP
ILHAVRNEAGVAAASIRLETKALASRGDKSRGLMLVGVEPADEAQVTMLSDAIVAGQPLTTGAPGVLIGEMLAEALAVRP
GQNIVFVGQGYDGSISSGKYPVRGIFRSKIDDLDGYVAVMPLPVVREFLSAPGGATAIALRLRERSRLEPVSAGLAERLG
DRYEVVGWPRLLPMVAVSSRFHEVTTYVVLLVFFVVVVFAVANPVLMSVMERTREFGIMLAVGMSRTRVLRLVLYESILL
GIVGLIVGNAVGWTVTAYFARAGIHLHGFEAGLRTMPGLSDVVYPVVSAERGVVLSVAVFVIAGLAALYPAAKAVQLRPI
EAIRGLPAAMRVSSRNTGDSRLPVFVLLALRNLLRNPRRTALMAAGAAFGIVGFVFILGFFDGFFDQTIENSTRYLTGHI
QVERKGFRKDYAPELAIDDAVSLLQAVRGTPGVIVGIAKKIRKSADLTGENSEVS
>Mature_535_residues
MMLLPLAVRNVLRNRRRSAITISSIAIGLAAMIFNWGFTAGMNREMVENTTRYFAGDAQVHLKGYHDDPILDLAMPDSAP
ILHAVRNEAGVAAASIRLETKALASRGDKSRGLMLVGVEPADEAQVTMLSDAIVAGQPLTTGAPGVLIGEMLAEALAVRP
GQNIVFVGQGYDGSISSGKYPVRGIFRSKIDDLDGYVAVMPLPVVREFLSAPGGATAIALRLRERSRLEPVSAGLAERLG
DRYEVVGWPRLLPMVAVSSRFHEVTTYVVLLVFFVVVVFAVANPVLMSVMERTREFGIMLAVGMSRTRVLRLVLYESILL
GIVGLIVGNAVGWTVTAYFARAGIHLHGFEAGLRTMPGLSDVVYPVVSAERGVVLSVAVFVIAGLAALYPAAKAVQLRPI
EAIRGLPAAMRVSSRNTGDSRLPVFVLLALRNLLRNPRRTALMAAGAAFGIVGFVFILGFFDGFFDQTIENSTRYLTGHI
QVERKGFRKDYAPELAIDDAVSLLQAVRGTPGVIVGIAKKIRKSADLTGENSEVS

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 57523; Mature: 57523

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLLPLAVRNVLRNRRRSAITISSIAIGLAAMIFNWGFTAGMNREMVENTTRYFAGDAQV
CEECHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEE
HLKGYHDDPILDLAMPDSAPILHAVRNEAGVAAASIRLETKALASRGDKSRGLMLVGVEP
EEECCCCCCEEEEECCCCCHHHHHHHCCCCCEEHHEEHHHHHHHHCCCCCCCEEEEECCC
ADEAQVTMLSDAIVAGQPLTTGAPGVLIGEMLAEALAVRPGQNIVFVGQGYDGSISSGKY
CCCCCEEEHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCC
PVRGIFRSKIDDLDGYVAVMPLPVVREFLSAPGGATAIALRLRERSRLEPVSAGLAERLG
CHHHHHHHHHHCCCCEEEEECHHHHHHHHCCCCCHHHHHEEHHHHHCCCHHHHHHHHHCC
DRYEVVGWPRLLPMVAVSSRFHEVTTYVVLLVFFVVVVFAVANPVLMSVMERTREFGIML
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
AVGMSRTRVLRLVLYESILLGIVGLIVGNAVGWTVTAYFARAGIHLHGFEAGLRTMPGLS
EECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEHHHHHHCCCCHH
DVVYPVVSAERGVVLSVAVFVIAGLAALYPAAKAVQLRPIEAIRGLPAAMRVSSRNTGDS
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHEEECCHHHHHCCCHHHEECCCCCCCC
RLPVFVLLALRNLLRNPRRTALMAAGAAFGIVGFVFILGFFDGFFDQTIENSTRYLTGHI
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
QVERKGFRKDYAPELAIDDAVSLLQAVRGTPGVIVGIAKKIRKSADLTGENSEVS
EEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MMLLPLAVRNVLRNRRRSAITISSIAIGLAAMIFNWGFTAGMNREMVENTTRYFAGDAQV
CEECHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEE
HLKGYHDDPILDLAMPDSAPILHAVRNEAGVAAASIRLETKALASRGDKSRGLMLVGVEP
EEECCCCCCEEEEECCCCCHHHHHHHCCCCCEEHHEEHHHHHHHHCCCCCCCEEEEECCC
ADEAQVTMLSDAIVAGQPLTTGAPGVLIGEMLAEALAVRPGQNIVFVGQGYDGSISSGKY
CCCCCEEEHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCC
PVRGIFRSKIDDLDGYVAVMPLPVVREFLSAPGGATAIALRLRERSRLEPVSAGLAERLG
CHHHHHHHHHHCCCCEEEEECHHHHHHHHCCCCCHHHHHEEHHHHHCCCHHHHHHHHHCC
DRYEVVGWPRLLPMVAVSSRFHEVTTYVVLLVFFVVVVFAVANPVLMSVMERTREFGIML
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
AVGMSRTRVLRLVLYESILLGIVGLIVGNAVGWTVTAYFARAGIHLHGFEAGLRTMPGLS
EECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEHHHHHHCCCCHH
DVVYPVVSAERGVVLSVAVFVIAGLAALYPAAKAVQLRPIEAIRGLPAAMRVSSRNTGDS
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHEEECCHHHHHCCCHHHEECCCCCCCC
RLPVFVLLALRNLLRNPRRTALMAAGAAFGIVGFVFILGFFDGFFDQTIENSTRYLTGHI
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
QVERKGFRKDYAPELAIDDAVSLLQAVRGTPGVIVGIAKKIRKSADLTGENSEVS
EEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]