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The map label for this gene is cusB [H]

Identifier: 187928730

GI number: 187928730

Start: 1732671

End: 1734221

Strand: Reverse

Name: cusB [H]

Synonym: Rpic_1647

Alternate gene names: 187928730

Gene position: 1734221-1732671 (Counterclockwise)

Preceding gene: 187928731

Following gene: 187928729

Centisome position: 43.99

GC content: 65.57

Gene sequence:

>1551_bases
ATGAACCGAACCATCTTTGCGCGCATTGCAGCCAGTCTGGTGTTGGCGAGCCTTGGCATGGGCGCCACCTACTACCTTGG
CGTGAGGCAGGGACAGCGGAGCGCGCCCACGCAGGCGGCAGCATCTGCCCAAGCCGCCGATGCCCCGCTCAAAGCGGGCG
ACATCGATCCCAAGACGGGCAAGCGGATTCTCTATTGGCAAGACCCCATGGCACCTGGCCAGCGTTTCGACAAACCAGGC
AAATCACCTTTCATGGACATGCCGCTTGCCCCCGTCTACGAGAATGGCGCCGGCGGGAGCGCCGCCGTCACGGTTGATGG
CCGTGTGGCACAGAATCTTGCTGTGCGCACGGCTGAGGTCAAGACCGGCCGGCTGGACGCCATGCTGGAAGTGCCCGGCA
ATATCGCCATCAACGAGCGCGGCATCGAGATCATTCAAGCGCGCGCCGCCGGCTTTGTCGAACGGGCGTACGCGAAAACC
ACGTTAGACCCGGTCAAGCGCGGGCAACCGCTGATCGTCGTCTACGCGCCGGAATGGGTCGCCGCACAAGAGGAGTACCT
GGCCGTTTCGCGTACGGCCAACGCCCTGCAGGGGGACCTGCGCAGCGCAGCGTTGCTGCGCATGCGCCAGGCCGGCATGA
CGGAGGCGCAGATCCGGCTGGTCGAATCCACCGGCAAGCCACAGCCACGGCTGGCGATTTCCAGCGACATCGATGGCGTC
ATCACCGAGGTCGGGGTCCGGGACGGCATGGCTGTCGCACCCGGCATGACGCTCTTCAAGATTGCCGACTTGTCCACCGT
GTGGGTCTTGGCGGAGATTCCCGAGAGCCAAGCATCGGCCATCCGCCCGGGCCAGGCGGTGACGGCCACGGCGACGGCAA
TCGCTGGACACGCGCTGACCGGCAAGGTGGATGCCATCCTGCCCGACGTCAATGCCAATACGCGAACCGTCAAGGTGCGC
GTCGAACTCCAGAACCGGGACCGCCGCCTCTTGCCCGGCATGTTCGCCAACGTGCGGTTTGGCGCGCAAGCCGGCCCGGA
CAAGCTGCTGGTCCCCACGGAGGCGTTGATTCGCACCGGTACGCGCACGATCGTCATGGTGGACGCCGGCAATGGCGGCT
TCAACCCCATCGAAGTCAAGACCGGAGCCGAAGCCAATGGGCAGACCGAAGTGACCGACGGTTTGAGCGCGGGACAGAAG
GTGGTGGTTTCCGGGCAGTTCCTGATTGATTCGGAAGCTAGCCTGCGCGGCACCGCCCAACGCATGGCATCGCCACCTGC
GGCCTCCGCGCCCGCAGCGGCCGCCATCGAGCATGAAGGCGTCGGCCGCATTGAGGCTGTCACCAGCGAAGGCCTGACGA
TCTCACATGGCGCGATTCCGTCCGCGCACTGGAGCGCGATGACAATGGATTTTGCCGCACCGCCCTCCGGCCTGCCAAAG
CGCTTCAAGCCTGGGGACCGTGTGCGCTTCCGGTTCCAACTGCATGACGATGGCATGGCAGTCCTGTCCTCGGTCGAGCC
GGCCGGCGCGGATCAGGGGGGCAAGCCATGA

Upstream 100 bases:

>100_bases
TCAAGCTCGAAGCGTCGACGGCCCAACTCTGGGCCGAGCTCGCCTTCCTCAAACCGCTCCCCACGGCAAACCAGCCGACC
TCCAACGTTGGAGTTCAACC

Downstream 100 bases:

>100_bases
TCGCACGGCTGATTCTCGCGTCCATCCGCAACCGCTTCCTGGTGCTGCTAGCGACCGTCATGCTGACGGCCTGGGGTCTG
TGGGCCGCGCGCAGCACGCC

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MNRTIFARIAASLVLASLGMGATYYLGVRQGQRSAPTQAAASAQAADAPLKAGDIDPKTGKRILYWQDPMAPGQRFDKPG
KSPFMDMPLAPVYENGAGGSAAVTVDGRVAQNLAVRTAEVKTGRLDAMLEVPGNIAINERGIEIIQARAAGFVERAYAKT
TLDPVKRGQPLIVVYAPEWVAAQEEYLAVSRTANALQGDLRSAALLRMRQAGMTEAQIRLVESTGKPQPRLAISSDIDGV
ITEVGVRDGMAVAPGMTLFKIADLSTVWVLAEIPESQASAIRPGQAVTATATAIAGHALTGKVDAILPDVNANTRTVKVR
VELQNRDRRLLPGMFANVRFGAQAGPDKLLVPTEALIRTGTRTIVMVDAGNGGFNPIEVKTGAEANGQTEVTDGLSAGQK
VVVSGQFLIDSEASLRGTAQRMASPPAASAPAAAAIEHEGVGRIEAVTSEGLTISHGAIPSAHWSAMTMDFAAPPSGLPK
RFKPGDRVRFRFQLHDDGMAVLSSVEPAGADQGGKP

Sequences:

>Translated_516_residues
MNRTIFARIAASLVLASLGMGATYYLGVRQGQRSAPTQAAASAQAADAPLKAGDIDPKTGKRILYWQDPMAPGQRFDKPG
KSPFMDMPLAPVYENGAGGSAAVTVDGRVAQNLAVRTAEVKTGRLDAMLEVPGNIAINERGIEIIQARAAGFVERAYAKT
TLDPVKRGQPLIVVYAPEWVAAQEEYLAVSRTANALQGDLRSAALLRMRQAGMTEAQIRLVESTGKPQPRLAISSDIDGV
ITEVGVRDGMAVAPGMTLFKIADLSTVWVLAEIPESQASAIRPGQAVTATATAIAGHALTGKVDAILPDVNANTRTVKVR
VELQNRDRRLLPGMFANVRFGAQAGPDKLLVPTEALIRTGTRTIVMVDAGNGGFNPIEVKTGAEANGQTEVTDGLSAGQK
VVVSGQFLIDSEASLRGTAQRMASPPAASAPAAAAIEHEGVGRIEAVTSEGLTISHGAIPSAHWSAMTMDFAAPPSGLPK
RFKPGDRVRFRFQLHDDGMAVLSSVEPAGADQGGKP
>Mature_516_residues
MNRTIFARIAASLVLASLGMGATYYLGVRQGQRSAPTQAAASAQAADAPLKAGDIDPKTGKRILYWQDPMAPGQRFDKPG
KSPFMDMPLAPVYENGAGGSAAVTVDGRVAQNLAVRTAEVKTGRLDAMLEVPGNIAINERGIEIIQARAAGFVERAYAKT
TLDPVKRGQPLIVVYAPEWVAAQEEYLAVSRTANALQGDLRSAALLRMRQAGMTEAQIRLVESTGKPQPRLAISSDIDGV
ITEVGVRDGMAVAPGMTLFKIADLSTVWVLAEIPESQASAIRPGQAVTATATAIAGHALTGKVDAILPDVNANTRTVKVR
VELQNRDRRLLPGMFANVRFGAQAGPDKLLVPTEALIRTGTRTIVMVDAGNGGFNPIEVKTGAEANGQTEVTDGLSAGQK
VVVSGQFLIDSEASLRGTAQRMASPPAASAPAAAAIEHEGVGRIEAVTSEGLTISHGAIPSAHWSAMTMDFAAPPSGLPK
RFKPGDRVRFRFQLHDDGMAVLSSVEPAGADQGGKP

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=371, Percent_Identity=42.3180592991914, Blast_Score=269, Evalue=4e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 54119; Mature: 54119

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRTIFARIAASLVLASLGMGATYYLGVRQGQRSAPTQAAASAQAADAPLKAGDIDPKTG
CCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHCCHHCCCCCCCCCCCCCCC
KRILYWQDPMAPGQRFDKPGKSPFMDMPLAPVYENGAGGSAAVTVDGRVAQNLAVRTAEV
CEEEEECCCCCCCHHCCCCCCCCCCCCCCCCEEECCCCCEEEEEECCHHHCCCEEEEEEE
KTGRLDAMLEVPGNIAINERGIEIIQARAAGFVERAYAKTTLDPVKRGQPLIVVYAPEWV
CCCCCEEEEECCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHH
AAQEEYLAVSRTANALQGDLRSAALLRMRQAGMTEAQIRLVESTGKPQPRLAISSDIDGV
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCCEEECCCCCHH
ITEVGVRDGMAVAPGMTLFKIADLSTVWVLAEIPESQASAIRPGQAVTATATAIAGHALT
HHHHCCCCCCEECCCCEEEEEECCCEEEEEEECCCCHHHHCCCCCCEEEEHHHHHCCCCC
GKVDAILPDVNANTRTVKVRVELQNRDRRLLPGMFANVRFGAQAGPDKLLVPTEALIRTG
CCEEEEECCCCCCCEEEEEEEEECCCCCEECCCHHHCEEECCCCCCCCEEECCHHHHHCC
TRTIVMVDAGNGGFNPIEVKTGAEANGQTEVTDGLSAGQKVVVSGQFLIDSEASLRGTAQ
CEEEEEEECCCCCCCEEEEECCCCCCCCCHHHCCCCCCCEEEEEEEEEECCCCHHHHHHH
RMASPPAASAPAAAAIEHEGVGRIEAVTSEGLTISHGAIPSAHWSAMTMDFAAPPSGLPK
HHCCCCCCCCCCHHHHCCCCCCEEEEECCCCEEEECCCCCCCCCCEEEEECCCCCCCCCC
RFKPGDRVRFRFQLHDDGMAVLSSVEPAGADQGGKP
CCCCCCEEEEEEEECCCCHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNRTIFARIAASLVLASLGMGATYYLGVRQGQRSAPTQAAASAQAADAPLKAGDIDPKTG
CCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHCCHHCCCCCCCCCCCCCCC
KRILYWQDPMAPGQRFDKPGKSPFMDMPLAPVYENGAGGSAAVTVDGRVAQNLAVRTAEV
CEEEEECCCCCCCHHCCCCCCCCCCCCCCCCEEECCCCCEEEEEECCHHHCCCEEEEEEE
KTGRLDAMLEVPGNIAINERGIEIIQARAAGFVERAYAKTTLDPVKRGQPLIVVYAPEWV
CCCCCEEEEECCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHH
AAQEEYLAVSRTANALQGDLRSAALLRMRQAGMTEAQIRLVESTGKPQPRLAISSDIDGV
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCCEEECCCCCHH
ITEVGVRDGMAVAPGMTLFKIADLSTVWVLAEIPESQASAIRPGQAVTATATAIAGHALT
HHHHCCCCCCEECCCCEEEEEECCCEEEEEEECCCCHHHHCCCCCCEEEEHHHHHCCCCC
GKVDAILPDVNANTRTVKVRVELQNRDRRLLPGMFANVRFGAQAGPDKLLVPTEALIRTG
CCEEEEECCCCCCCEEEEEEEEECCCCCEECCCHHHCEEECCCCCCCCEEECCHHHHHCC
TRTIVMVDAGNGGFNPIEVKTGAEANGQTEVTDGLSAGQKVVVSGQFLIDSEASLRGTAQ
CEEEEEEECCCCCCCEEEEECCCCCCCCCHHHCCCCCCCEEEEEEEEEECCCCHHHHHHH
RMASPPAASAPAAAAIEHEGVGRIEAVTSEGLTISHGAIPSAHWSAMTMDFAAPPSGLPK
HHCCCCCCCCCCHHHHCCCCCCEEEEECCCCEEEECCCCCCCCCCEEEEECCCCCCCCCC
RFKPGDRVRFRFQLHDDGMAVLSSVEPAGADQGGKP
CCCCCCEEEEEEEECCCCHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]