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The map label for this gene is surA [C]

Identifier: 187928546

GI number: 187928546

Start: 1551484

End: 1552281

Strand: Direct

Name: surA [C]

Synonym: Rpic_1460

Alternate gene names: 187928546

Gene position: 1551484-1552281 (Clockwise)

Preceding gene: 187928545

Following gene: 187928547

Centisome position: 39.35

GC content: 62.16

Gene sequence:

>798_bases
ATGAAGATTTCCAGCCTCACTGCCAGCCTGCTGGCTGCTGCCCTTGCTGCGACCGTTGCTCCCGCGATGGCGCAAAACGC
CGCGGTGGTCAACGGCAAAGCCATCCCGAGCGCCAAGGTGGACGCGCTGATCAAGAAGTCGGGCCAGCCCGAATCGCCCG
AGCTGCGCGCCAGGGCCCGCGACATGCTGGTCGACCGTGAACTGATCGAGCAGGACGCGGCCAAACGCGGTCTGCTGGAG
CGTGACGACATTCAGGAACAACTCGCTGCTGCGCGCCTGAATGTGCTCGTGGCCGCCGAGTTCGAAGACTACGTCAAGAA
CAGCCCTGCCACCGAAGACGAACTGCACAAGCAGTACGACAAGATCAAGGCGCAGTTCGGCAACGGCAAGGAATACCACG
CCCACCACATCCTGGTGGACAAGGAAGCCGACGCGAAGGCCATCATCGCCAAGCTCAAGGCCGGCGCCAAGTTTGAAGAC
ATCGCCAAGGCGCAATCGAAGGACAAGGGATCGGGCGCCAACGGCGGCGATCTGGACTGGGCGAACCCGGGCACCTACGT
GCCGGAATTCTCGGCCGCTCTCACCGGCCTGAAGAAGGGGCAGATCACCCAGACGCCGGTCAAGACGCAATTCGGCTGGC
ACGTGATCCGCCTGGACGACACGCGCGACGCCAAGATCCCGTCGTACGAAGAGGTCAAGCCGCAACTGCTCGAGATGATG
ATGGGCGACCAGAACTGGCAACGCAGCAAGTTCCAGGCGATGCTGAAAGACCTGCGCGAAAAAGCGAAGATCCAGTAA

Upstream 100 bases:

>100_bases
GCCGGCGGCAATCCATGCGCTGGCGATCCGCGCGGTCACTCCCGAAGAAAACACGTAAGCGCATTCCACGCTCACTCGTC
CTTCCCTCGAACGCAATCCC

Downstream 100 bases:

>100_bases
GCAGAGCAGCCCGTTGGGGCAGTGAAAAAAGGGGCCGCGTGCCCCTTTTTGATTTGATGGCGACGTTGCATCGCACGCAA
TCGGAATCCCCTCCCTGCCC

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MKISSLTASLLAAALAATVAPAMAQNAAVVNGKAIPSAKVDALIKKSGQPESPELRARARDMLVDRELIEQDAAKRGLLE
RDDIQEQLAAARLNVLVAAEFEDYVKNSPATEDELHKQYDKIKAQFGNGKEYHAHHILVDKEADAKAIIAKLKAGAKFED
IAKAQSKDKGSGANGGDLDWANPGTYVPEFSAALTGLKKGQITQTPVKTQFGWHVIRLDDTRDAKIPSYEEVKPQLLEMM
MGDQNWQRSKFQAMLKDLREKAKIQ

Sequences:

>Translated_265_residues
MKISSLTASLLAAALAATVAPAMAQNAAVVNGKAIPSAKVDALIKKSGQPESPELRARARDMLVDRELIEQDAAKRGLLE
RDDIQEQLAAARLNVLVAAEFEDYVKNSPATEDELHKQYDKIKAQFGNGKEYHAHHILVDKEADAKAIIAKLKAGAKFED
IAKAQSKDKGSGANGGDLDWANPGTYVPEFSAALTGLKKGQITQTPVKTQFGWHVIRLDDTRDAKIPSYEEVKPQLLEMM
MGDQNWQRSKFQAMLKDLREKAKIQ
>Mature_265_residues
MKISSLTASLLAAALAATVAPAMAQNAAVVNGKAIPSAKVDALIKKSGQPESPELRARARDMLVDRELIEQDAAKRGLLE
RDDIQEQLAAARLNVLVAAEFEDYVKNSPATEDELHKQYDKIKAQFGNGKEYHAHHILVDKEADAKAIIAKLKAGAKFED
IAKAQSKDKGSGANGGDLDWANPGTYVPEFSAALTGLKKGQITQTPVKTQFGWHVIRLDDTRDAKIPSYEEVKPQLLEMM
MGDQNWQRSKFQAMLKDLREKAKIQ

Specific function: Assist In The Folding Of Extracytoplasmic Proteins. Essential For The Survival Of E.Coli In Stationary Phase. [C]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Homo sapiens, GI38679892, Length=101, Percent_Identity=34.6534653465347, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1786238, Length=103, Percent_Identity=45.6310679611651, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786645, Length=126, Percent_Identity=34.1269841269841, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17537235, Length=101, Percent_Identity=37.6237623762376, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 29060; Mature: 29060

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISSLTASLLAAALAATVAPAMAQNAAVVNGKAIPSAKVDALIKKSGQPESPELRARAR
CCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHH
DMLVDRELIEQDAAKRGLLERDDIQEQLAAARLNVLVAAEFEDYVKNSPATEDELHKQYD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEECHHHHHCCCCCCHHHHHHHHH
KIKAQFGNGKEYHAHHILVDKEADAKAIIAKLKAGAKFEDIAKAQSKDKGSGANGGDLDW
HHHHHCCCCCCEEEEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCC
ANPGTYVPEFSAALTGLKKGQITQTPVKTQFGWHVIRLDDTRDAKIPSYEEVKPQLLEMM
CCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHH
MGDQNWQRSKFQAMLKDLREKAKIQ
HCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKISSLTASLLAAALAATVAPAMAQNAAVVNGKAIPSAKVDALIKKSGQPESPELRARAR
CCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHH
DMLVDRELIEQDAAKRGLLERDDIQEQLAAARLNVLVAAEFEDYVKNSPATEDELHKQYD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEECHHHHHCCCCCCHHHHHHHHH
KIKAQFGNGKEYHAHHILVDKEADAKAIIAKLKAGAKFEDIAKAQSKDKGSGANGGDLDW
HHHHHCCCCCCEEEEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCC
ANPGTYVPEFSAALTGLKKGQITQTPVKTQFGWHVIRLDDTRDAKIPSYEEVKPQLLEMM
CCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHH
MGDQNWQRSKFQAMLKDLREKAKIQ
HCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]