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The map label for this gene is msrB [H]

Identifier: 187928543

GI number: 187928543

Start: 1550162

End: 1550548

Strand: Direct

Name: msrB [H]

Synonym: Rpic_1457

Alternate gene names: 187928543

Gene position: 1550162-1550548 (Clockwise)

Preceding gene: 187928542

Following gene: 187928544

Centisome position: 39.32

GC content: 62.02

Gene sequence:

>387_bases
ATGACCGTCAAGAAATCCGACGCCGAATGGCGCGACCAACTCTCCGACATCGAATACCGTGTCACCCGGGAAGCGGCCAC
TGAGCGCCCCTTCACCGGCAAGTACTGGGACCACTGGGATCGCGGCGTCTACAACTGCGTCTGCTGCGGCACGCCGCTGT
TTGAATCGTCGACCAAGTTCGATGCGGGCTGCGGCTGGCCGAGCTATTTCCAGCCCATCAACGGCGAGGTGATCGACGAG
AAGACGGACCGCTCGCACGGCATGCTGCGCATCGAAGTGCAGTGCAAGAATTGTGGCGCGCACCTCGGCCACGTGTTCGA
GGATGGCCCCGCGCCCACTGGCCTGCGGTATTGCATCAACTCGGCTGCGCTAAAATTCGGCGATTGA

Upstream 100 bases:

>100_bases
CCGCGCCTGTCAGGATTGCCGCTGCCGCACGACAAAACAACGTCAGCCGCTCGATCGCTCCATCCCGCGGTTGCCGAATC
CAACAAGGAGTCTCATCACC

Downstream 100 bases:

>100_bases
TCTTTCCCTAATCATCGTCCGTATAGGCCCGCACAAGCGCGTTCCCGCATGAAATTCCTGTTCGATCTGTTCCCGGTCAT
CCTGTTCTTTGCTGCCTTCA

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 128; Mature: 127

Protein sequence:

>128_residues
MTVKKSDAEWRDQLSDIEYRVTREAATERPFTGKYWDHWDRGVYNCVCCGTPLFESSTKFDAGCGWPSYFQPINGEVIDE
KTDRSHGMLRIEVQCKNCGAHLGHVFEDGPAPTGLRYCINSAALKFGD

Sequences:

>Translated_128_residues
MTVKKSDAEWRDQLSDIEYRVTREAATERPFTGKYWDHWDRGVYNCVCCGTPLFESSTKFDAGCGWPSYFQPINGEVIDE
KTDRSHGMLRIEVQCKNCGAHLGHVFEDGPAPTGLRYCINSAALKFGD
>Mature_127_residues
TVKKSDAEWRDQLSDIEYRVTREAATERPFTGKYWDHWDRGVYNCVCCGTPLFESSTKFDAGCGWPSYFQPINGEVIDEK
TDRSHGMLRIEVQCKNCGAHLGHVFEDGPAPTGLRYCINSAALKFGD

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=121, Percent_Identity=57.8512396694215, Blast_Score=154, Evalue=2e-38,
Organism=Homo sapiens, GI301336162, Length=121, Percent_Identity=57.8512396694215, Blast_Score=154, Evalue=2e-38,
Organism=Homo sapiens, GI73089054, Length=121, Percent_Identity=57.8512396694215, Blast_Score=154, Evalue=2e-38,
Organism=Homo sapiens, GI37620216, Length=121, Percent_Identity=57.8512396694215, Blast_Score=154, Evalue=2e-38,
Organism=Homo sapiens, GI117606353, Length=128, Percent_Identity=47.65625, Blast_Score=126, Evalue=6e-30,
Organism=Homo sapiens, GI7706511, Length=93, Percent_Identity=34.4086021505376, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1788077, Length=128, Percent_Identity=53.125, Blast_Score=152, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI17553450, Length=121, Percent_Identity=52.8925619834711, Blast_Score=132, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI115532676, Length=121, Percent_Identity=52.8925619834711, Blast_Score=132, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6319816, Length=132, Percent_Identity=40.1515151515151, Blast_Score=109, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24645799, Length=127, Percent_Identity=49.6062992125984, Blast_Score=135, Evalue=6e-33,
Organism=Drosophila melanogaster, GI221378664, Length=127, Percent_Identity=48.8188976377953, Blast_Score=135, Evalue=8e-33,
Organism=Drosophila melanogaster, GI45553335, Length=127, Percent_Identity=49.6062992125984, Blast_Score=135, Evalue=8e-33,
Organism=Drosophila melanogaster, GI21356369, Length=127, Percent_Identity=49.6062992125984, Blast_Score=135, Evalue=8e-33,
Organism=Drosophila melanogaster, GI221378662, Length=134, Percent_Identity=47.0149253731343, Blast_Score=132, Evalue=5e-32,
Organism=Drosophila melanogaster, GI24645801, Length=138, Percent_Identity=45.6521739130435, Blast_Score=130, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24645804, Length=138, Percent_Identity=45.6521739130435, Blast_Score=129, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 14488; Mature: 14357

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
5.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVKKSDAEWRDQLSDIEYRVTREAATERPFTGKYWDHWDRGVYNCVCCGTPLFESSTKF
CCCCCCCCHHHHHHHHHHHHEEHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCC
DAGCGWPSYFQPINGEVIDEKTDRSHGMLRIEVQCKNCGAHLGHVFEDGPAPTGLRYCIN
CCCCCCCHHCCCCCCEEECCCCCCCCCEEEEEEEECCCCCHHCHHHCCCCCCCHHHHHHH
SAALKFGD
HHHHCCCC
>Mature Secondary Structure 
TVKKSDAEWRDQLSDIEYRVTREAATERPFTGKYWDHWDRGVYNCVCCGTPLFESSTKF
CCCCCCCHHHHHHHHHHHHEEHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCC
DAGCGWPSYFQPINGEVIDEKTDRSHGMLRIEVQCKNCGAHLGHVFEDGPAPTGLRYCIN
CCCCCCCHHCCCCCCEEECCCCCCCCCEEEEEEEECCCCCHHCHHHCCCCCCCHHHHHHH
SAALKFGD
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]