| Definition | Ralstonia pickettii 12J chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010682 |
| Length | 3,942,557 |
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The map label for this gene is gno [H]
Identifier: 187928529
GI number: 187928529
Start: 1530475
End: 1531257
Strand: Reverse
Name: gno [H]
Synonym: Rpic_1443
Alternate gene names: 187928529
Gene position: 1531257-1530475 (Counterclockwise)
Preceding gene: 187928530
Following gene: 187928528
Centisome position: 38.84
GC content: 64.75
Gene sequence:
>783_bases ATGGGTACGCTGAAACACCTCTTCGATCTTTCCGGCAAGACGGCGCTGATCACCGGCGGCTCGCGCGGGCTCGGCCTGCA GATTGCCGAAGCATTGGGCGAGCAGGGCGCGCGCATCGTTTTGTCTGCCCGCAAGGCCGATGAGCTGAAGGAAGCGCAGG CGCACCTGAAATCCCTCGGCATCGAGGCCGACTGGATCGCCGCCGACGGCGCCGTCGAAGCAGACATCCAGCGCCTAGCC GACGAGGCGCTGGCCAAACTCGGCCACGTCGACATTCTCGTCAACAACGCGGGCGCGACGTGGGGCGCACCGGCTGAAGA CCACCCGGTCGAAGCGTGGGACAAGGTGATGAACCTGAACATCCGCGGCTTGTTCCTGCTCACGCAGCAGATCGGCAAGC GCTCGATGATCCCGCGCAAGTACGGAAAGATCGTCAACGTGGCGTCGATTGCAGGCCTGAAGGGCAACCCGCCGGGCTCG CTGGATACGATCGCCTACAACACCAGCAAGGGTGCGGTGGTCAACTTCACTCGCGCGCTGGCGGGCGAGTGGGGCGAGCA CAACATCACCGTCAATGCGATTGCACCTGGCTTCTTCCCGTCGAAGATGACGCGCGGCTCGCTAGAGAAGCTCGGCGTGG ACAAGCTAGCCGAACGCTCGCCGCTGCACCGCATTGGCGACGACGAAGACCTCAAGGGCGTGGCCGCGCTGTTCGCGTCG GATGCGTCCAAGCACATCACGGGCCAGATCCTCGCCGTCGACGGCGGCGTGAGCGTGGTCTAA
Upstream 100 bases:
>100_bases CAGATCGTGCTGCTGGGCTCGCTCGACACGACCACGCTGGACATGCAGGACGCCTGGTTCTGACGGCATCGCACAACCAC AACGAGACACAGGAGACACC
Downstream 100 bases:
>100_bases TTTCGGCTGCTTCTTACTCTTTCTGACGCAGCATGAACGCAGACAACAACGGTTTTCCGATCGACATCCCTTTCCTCAAG CTTCTCGGCATGCGCTGCCT
Product: gluconate 5-dehydrogenase
Products: NA
Alternate protein names: 5-keto-D-gluconate 5-reductase [H]
Number of amino acids: Translated: 260; Mature: 259
Protein sequence:
>260_residues MGTLKHLFDLSGKTALITGGSRGLGLQIAEALGEQGARIVLSARKADELKEAQAHLKSLGIEADWIAADGAVEADIQRLA DEALAKLGHVDILVNNAGATWGAPAEDHPVEAWDKVMNLNIRGLFLLTQQIGKRSMIPRKYGKIVNVASIAGLKGNPPGS LDTIAYNTSKGAVVNFTRALAGEWGEHNITVNAIAPGFFPSKMTRGSLEKLGVDKLAERSPLHRIGDDEDLKGVAALFAS DASKHITGQILAVDGGVSVV
Sequences:
>Translated_260_residues MGTLKHLFDLSGKTALITGGSRGLGLQIAEALGEQGARIVLSARKADELKEAQAHLKSLGIEADWIAADGAVEADIQRLA DEALAKLGHVDILVNNAGATWGAPAEDHPVEAWDKVMNLNIRGLFLLTQQIGKRSMIPRKYGKIVNVASIAGLKGNPPGS LDTIAYNTSKGAVVNFTRALAGEWGEHNITVNAIAPGFFPSKMTRGSLEKLGVDKLAERSPLHRIGDDEDLKGVAALFAS DASKHITGQILAVDGGVSVV >Mature_259_residues GTLKHLFDLSGKTALITGGSRGLGLQIAEALGEQGARIVLSARKADELKEAQAHLKSLGIEADWIAADGAVEADIQRLAD EALAKLGHVDILVNNAGATWGAPAEDHPVEAWDKVMNLNIRGLFLLTQQIGKRSMIPRKYGKIVNVASIAGLKGNPPGSL DTIAYNTSKGAVVNFTRALAGEWGEHNITVNAIAPGFFPSKMTRGSLEKLGVDKLAERSPLHRIGDDEDLKGVAALFASD ASKHITGQILAVDGGVSVV
Specific function: Involved in the non-phosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate. Dependent on NADP, almost inactive with NAD [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=32.1285140562249, Blast_Score=123, Evalue=2e-28, Organism=Homo sapiens, GI40254992, Length=248, Percent_Identity=35.8870967741936, Blast_Score=122, Evalue=4e-28, Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=31.2741312741313, Blast_Score=110, Evalue=1e-24, Organism=Homo sapiens, GI5031737, Length=255, Percent_Identity=31.7647058823529, Blast_Score=110, Evalue=2e-24, Organism=Homo sapiens, GI10190704, Length=267, Percent_Identity=32.5842696629214, Blast_Score=108, Evalue=7e-24, Organism=Homo sapiens, GI15277342, Length=260, Percent_Identity=31.9230769230769, Blast_Score=100, Evalue=9e-22, Organism=Homo sapiens, GI126723750, Length=254, Percent_Identity=28.740157480315, Blast_Score=99, Evalue=4e-21, Organism=Homo sapiens, GI4503301, Length=255, Percent_Identity=29.0196078431373, Blast_Score=95, Evalue=6e-20, Organism=Homo sapiens, GI7705925, Length=249, Percent_Identity=31.3253012048193, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI33667109, Length=202, Percent_Identity=31.1881188118812, Blast_Score=91, Evalue=8e-19, Organism=Homo sapiens, GI4758504, Length=263, Percent_Identity=30.7984790874525, Blast_Score=90, Evalue=3e-18, Organism=Homo sapiens, GI66933014, Length=256, Percent_Identity=28.125, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI210032110, Length=206, Percent_Identity=30.0970873786408, Blast_Score=86, Evalue=5e-17, Organism=Homo sapiens, GI209862901, Length=253, Percent_Identity=24.901185770751, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI19923983, Length=253, Percent_Identity=24.901185770751, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI126723191, Length=186, Percent_Identity=32.258064516129, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI20149619, Length=201, Percent_Identity=31.8407960199005, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI7705855, Length=209, Percent_Identity=31.5789473684211, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI4503817, Length=192, Percent_Identity=30.7291666666667, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI7706318, Length=211, Percent_Identity=32.2274881516588, Blast_Score=78, Evalue=1e-14, Organism=Homo sapiens, GI226371731, Length=214, Percent_Identity=29.9065420560748, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI40254986, Length=200, Percent_Identity=32.5, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI83715985, Length=264, Percent_Identity=29.5454545454545, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI59889578, Length=236, Percent_Identity=27.5423728813559, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI157739938, Length=197, Percent_Identity=29.4416243654822, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI109715829, Length=197, Percent_Identity=29.9492385786802, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI31542939, Length=220, Percent_Identity=32.7272727272727, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI142976729, Length=210, Percent_Identity=29.0476190476191, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI31543615, Length=202, Percent_Identity=32.1782178217822, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI4504505, Length=204, Percent_Identity=28.921568627451, Blast_Score=65, Evalue=5e-11, Organism=Escherichia coli, GI1790717, Length=258, Percent_Identity=36.046511627907, Blast_Score=154, Evalue=7e-39, Organism=Escherichia coli, GI87082160, Length=254, Percent_Identity=35.0393700787402, Blast_Score=147, Evalue=5e-37, Organism=Escherichia coli, GI1789208, Length=257, Percent_Identity=37.3540856031128, Blast_Score=142, Evalue=1e-35, Organism=Escherichia coli, GI1787335, Length=253, Percent_Identity=32.8063241106719, Blast_Score=131, Evalue=4e-32, Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=33.6032388663968, Blast_Score=115, Evalue=4e-27, Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=31.9066147859922, Blast_Score=112, Evalue=3e-26, Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=32.8063241106719, Blast_Score=108, Evalue=3e-25, Organism=Escherichia coli, GI2367175, Length=253, Percent_Identity=31.2252964426877, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=27.8884462151394, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI1789057, Length=262, Percent_Identity=25.9541984732824, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1787820, Length=184, Percent_Identity=28.804347826087, Blast_Score=68, Evalue=5e-13, Organism=Escherichia coli, GI1786812, Length=267, Percent_Identity=27.7153558052434, Blast_Score=68, Evalue=6e-13, Organism=Escherichia coli, GI1787526, Length=232, Percent_Identity=26.2931034482759, Blast_Score=67, Evalue=2e-12, Organism=Escherichia coli, GI2367365, Length=247, Percent_Identity=27.5303643724696, Blast_Score=65, Evalue=5e-12, Organism=Escherichia coli, GI1786701, Length=193, Percent_Identity=30.0518134715026, Blast_Score=63, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17560220, Length=273, Percent_Identity=34.4322344322344, Blast_Score=124, Evalue=7e-29, Organism=Caenorhabditis elegans, GI17562906, Length=272, Percent_Identity=32.7205882352941, Blast_Score=123, Evalue=9e-29, Organism=Caenorhabditis elegans, GI17561402, Length=258, Percent_Identity=35.2713178294574, Blast_Score=123, Evalue=1e-28, Organism=Caenorhabditis elegans, GI193204405, Length=272, Percent_Identity=35.6617647058824, Blast_Score=120, Evalue=6e-28, Organism=Caenorhabditis elegans, GI17562908, Length=270, Percent_Identity=32.2222222222222, Blast_Score=119, Evalue=1e-27, Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=32.258064516129, Blast_Score=118, Evalue=3e-27, Organism=Caenorhabditis elegans, GI17531453, Length=268, Percent_Identity=33.5820895522388, Blast_Score=117, Evalue=5e-27, Organism=Caenorhabditis elegans, GI17560150, Length=268, Percent_Identity=32.089552238806, Blast_Score=117, Evalue=6e-27, Organism=Caenorhabditis elegans, GI17562990, Length=273, Percent_Identity=32.967032967033, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17559104, Length=267, Percent_Identity=30.3370786516854, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI25147288, Length=258, Percent_Identity=31.7829457364341, Blast_Score=112, Evalue=3e-25, Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=31.6205533596838, Blast_Score=110, Evalue=7e-25, Organism=Caenorhabditis elegans, GI71994600, Length=258, Percent_Identity=31.7829457364341, Blast_Score=109, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=30.9701492537313, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17538480, Length=274, Percent_Identity=31.7518248175182, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17560676, Length=259, Percent_Identity=28.957528957529, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17551412, Length=270, Percent_Identity=30.3703703703704, Blast_Score=103, Evalue=9e-23, Organism=Caenorhabditis elegans, GI17562904, Length=270, Percent_Identity=27.7777777777778, Blast_Score=103, Evalue=9e-23, Organism=Caenorhabditis elegans, GI17562910, Length=271, Percent_Identity=29.520295202952, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17536025, Length=253, Percent_Identity=28.4584980237154, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17561272, Length=254, Percent_Identity=29.9212598425197, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17565030, Length=271, Percent_Identity=29.1512915129151, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17536651, Length=253, Percent_Identity=27.6679841897233, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI115534694, Length=256, Percent_Identity=30.46875, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17538486, Length=270, Percent_Identity=27.7777777777778, Blast_Score=92, Evalue=4e-19, Organism=Caenorhabditis elegans, GI193203115, Length=200, Percent_Identity=34, Blast_Score=91, Evalue=9e-19, Organism=Caenorhabditis elegans, GI193203117, Length=202, Percent_Identity=33.6633663366337, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17563726, Length=270, Percent_Identity=27.037037037037, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17544670, Length=266, Percent_Identity=27.4436090225564, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI72000259, Length=269, Percent_Identity=27.1375464684015, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI71982365, Length=199, Percent_Identity=31.6582914572864, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17555612, Length=206, Percent_Identity=33.9805825242718, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17564282, Length=205, Percent_Identity=27.8048780487805, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI71997099, Length=206, Percent_Identity=29.126213592233, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17558006, Length=213, Percent_Identity=28.169014084507, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17568967, Length=199, Percent_Identity=27.6381909547739, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI17558628, Length=201, Percent_Identity=30.8457711442786, Blast_Score=67, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=226, Percent_Identity=31.858407079646, Blast_Score=66, Evalue=5e-12, Organism=Saccharomyces cerevisiae, GI6322861, Length=225, Percent_Identity=28.8888888888889, Blast_Score=65, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=257, Percent_Identity=24.124513618677, Blast_Score=63, Evalue=4e-11, Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=35.2941176470588, Blast_Score=131, Evalue=4e-31, Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=35.2, Blast_Score=127, Evalue=7e-30, Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=35.2, Blast_Score=125, Evalue=2e-29, Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=33.0708661417323, Blast_Score=125, Evalue=4e-29, Organism=Drosophila melanogaster, GI21355319, Length=266, Percent_Identity=30.8270676691729, Blast_Score=121, Evalue=5e-28, Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=32.9365079365079, Blast_Score=112, Evalue=4e-25, Organism=Drosophila melanogaster, GI24644337, Length=259, Percent_Identity=31.6602316602317, Blast_Score=101, Evalue=4e-22, Organism=Drosophila melanogaster, GI21358495, Length=229, Percent_Identity=30.5676855895196, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI24643142, Length=267, Percent_Identity=29.5880149812734, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI28574402, Length=203, Percent_Identity=32.512315270936, Blast_Score=87, Evalue=8e-18, Organism=Drosophila melanogaster, GI24584744, Length=203, Percent_Identity=32.512315270936, Blast_Score=87, Evalue=8e-18, Organism=Drosophila melanogaster, GI161076933, Length=206, Percent_Identity=32.0388349514563, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI24584748, Length=206, Percent_Identity=32.0388349514563, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI17737361, Length=266, Percent_Identity=28.1954887218045, Blast_Score=83, Evalue=1e-16, Organism=Drosophila melanogaster, GI21357673, Length=200, Percent_Identity=30.5, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI24640442, Length=207, Percent_Identity=28.5024154589372, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI18859837, Length=220, Percent_Identity=27.7272727272727, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24641232, Length=214, Percent_Identity=29.9065420560748, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI21355631, Length=176, Percent_Identity=29.5454545454545, Blast_Score=64, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.69 [H]
Molecular weight: Translated: 27353; Mature: 27221
Theoretical pI: Translated: 6.90; Mature: 6.90
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 1.5 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 1.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MGTLKHLFDLSGKTALITGGSRGLGLQIAEALGEQGARIVLSARKADELKEAQAHLKSLG CCCHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCC IEADWIAADGAVEADIQRLADEALAKLGHVDILVNNAGATWGAPAEDHPVEAWDKVMNLN CCCEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCC IRGLFLLTQQIGKRSMIPRKYGKIVNVASIAGLKGNPPGSLDTIAYNTSKGAVVNFTRAL CHHHHHHHHHHCCCCCCCHHHHCEEEHHHHCCCCCCCCCCCCEEEEECCCCCEEEHHHHH AGEWGEHNITVNAIAPGFFPSKMTRGSLEKLGVDKLAERSPLHRIGDDEDLKGVAALFAS CCCCCCCCEEEEEECCCCCCHHHCCCHHHHHCHHHHHHCCCHHHCCCCCHHHHHHHHHHC DASKHITGQILAVDGGVSVV CCCCCCEEEEEEECCCCCCC >Mature Secondary Structure GTLKHLFDLSGKTALITGGSRGLGLQIAEALGEQGARIVLSARKADELKEAQAHLKSLG CCHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCC IEADWIAADGAVEADIQRLADEALAKLGHVDILVNNAGATWGAPAEDHPVEAWDKVMNLN CCCEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCC IRGLFLLTQQIGKRSMIPRKYGKIVNVASIAGLKGNPPGSLDTIAYNTSKGAVVNFTRAL CHHHHHHHHHHCCCCCCCHHHHCEEEHHHHCCCCCCCCCCCCEEEEECCCCCEEEHHHHH AGEWGEHNITVNAIAPGFFPSKMTRGSLEKLGVDKLAERSPLHRIGDDEDLKGVAALFAS CCCCCCCCEEEEEECCCCCCHHHCCCHHHHHCHHHHHHCCCHHHCCCCCHHHHHHHHHHC DASKHITGQILAVDGGVSVV CCCCCCEEEEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7751271 [H]