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The map label for this gene is yfhM [H]

Identifier: 187928522

GI number: 187928522

Start: 1523616

End: 1524542

Strand: Reverse

Name: yfhM [H]

Synonym: Rpic_1436

Alternate gene names: 187928522

Gene position: 1524542-1523616 (Counterclockwise)

Preceding gene: 187928523

Following gene: 187928520

Centisome position: 38.67

GC content: 64.08

Gene sequence:

>927_bases
ATGAACACTGCAACGGCTGCCGCCATCACGGAATCGCAATTCGCCGATCTGCCCAACGGCACGCGGCTCCATTACGCCAG
CGCCGGCAAGCGCGGCGCACCGCTGATGCTGTTCGTACACGGCTTTCCGGAGTTCTGGTACGAGTGGGAAGCGCAGCTGG
CTGCGTTTGGCGCCACGCACTTTGCCGTAGCGCCCGACATGCGTGGGTTCAACCTGTCGAGCAAGCCGGCTGCGGTGGAT
GCGTATCGACCGAAATTTCTCGTGCAGGATCTGGAGCAGTTCATCGCGGCGCTCGGCTATGAGCGAGCGATTGTGGTCGC
GCATGACTGGGGCGGGGCGATCTGCTGGAACCTTGCCATTCAGCATCCGGAGTTGGTCGAGCGGTTGGTGATCGTCAATT
CGCCGCACCCGTGGGTGTTTGCGAATGCGCTGCTGAGCGATCCCGCGCAGCAGGCTTCATCAGCGTATATGAATTGGCTA
CGCCAGCCGGGCTCGGAGGAGGCGCTGGCCGCCAACGAGTTCGAAAAGCTCGAGGGCTTCTTCAGCGGTATGGGCCAGCC
CGTGGCCGAATGGTTCACGCCCGAGGTGCGGGCGCGCTATCACGCCGCCTGGAGCCAGCCGGGCGAAGGCGGCTCGCATG
GCCTGACCGGCGGCGTCAACTATTACCGCGCCTCGCCGTTGCACCCGCCCACCGAGGGCACGGCGCCGTTGCGCATCGAC
CAGATGCCGCCCGAGGCGTTTATTGTGAAGGTGCCCACGCTCGTGATCTGGGGCGAGATGGACATGGCGCTGCCGAAAAG
CCTGCTCAACGGGTTGGAACGCTTCATTCCTGACATGCGCCTGGAGCGCATTCCCGACGGCACGCACTGGGTCGTGCACG
AACAACCGGAGCGCGTTAATGCGCTGATCCGGTCGTTCGTTTCCTGA

Upstream 100 bases:

>100_bases
GTCCGATCCGTTTGAAGGCAAGCCAGACGTGCGTGCGCGTCTGGTCGATGCGCTGCGCGGGTAACCCCACCTCCACGACT
GCCATAACGCCGAGATCGCC

Downstream 100 bases:

>100_bases
ACGCCCGCGTTACATCGACTCCGCCAGCATGCGGCGGTAGTCGTCCGCTGTGGCGATGCGCGGGTTGGTCTTGTGGCAGT
GGTCGAGCAGGGCGCCTTCC

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MNTATAAAITESQFADLPNGTRLHYASAGKRGAPLMLFVHGFPEFWYEWEAQLAAFGATHFAVAPDMRGFNLSSKPAAVD
AYRPKFLVQDLEQFIAALGYERAIVVAHDWGGAICWNLAIQHPELVERLVIVNSPHPWVFANALLSDPAQQASSAYMNWL
RQPGSEEALAANEFEKLEGFFSGMGQPVAEWFTPEVRARYHAAWSQPGEGGSHGLTGGVNYYRASPLHPPTEGTAPLRID
QMPPEAFIVKVPTLVIWGEMDMALPKSLLNGLERFIPDMRLERIPDGTHWVVHEQPERVNALIRSFVS

Sequences:

>Translated_308_residues
MNTATAAAITESQFADLPNGTRLHYASAGKRGAPLMLFVHGFPEFWYEWEAQLAAFGATHFAVAPDMRGFNLSSKPAAVD
AYRPKFLVQDLEQFIAALGYERAIVVAHDWGGAICWNLAIQHPELVERLVIVNSPHPWVFANALLSDPAQQASSAYMNWL
RQPGSEEALAANEFEKLEGFFSGMGQPVAEWFTPEVRARYHAAWSQPGEGGSHGLTGGVNYYRASPLHPPTEGTAPLRID
QMPPEAFIVKVPTLVIWGEMDMALPKSLLNGLERFIPDMRLERIPDGTHWVVHEQPERVNALIRSFVS
>Mature_308_residues
MNTATAAAITESQFADLPNGTRLHYASAGKRGAPLMLFVHGFPEFWYEWEAQLAAFGATHFAVAPDMRGFNLSSKPAAVD
AYRPKFLVQDLEQFIAALGYERAIVVAHDWGGAICWNLAIQHPELVERLVIVNSPHPWVFANALLSDPAQQASSAYMNWL
RQPGSEEALAANEFEKLEGFFSGMGQPVAEWFTPEVRARYHAAWSQPGEGGSHGLTGGVNYYRASPLHPPTEGTAPLRID
QMPPEAFIVKVPTLVIWGEMDMALPKSLLNGLERFIPDMRLERIPDGTHWVVHEQPERVNALIRSFVS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI218777837, Length=296, Percent_Identity=34.1216216216216, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI218777840, Length=307, Percent_Identity=35.5048859934853, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI13376164, Length=307, Percent_Identity=35.5048859934853, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI27597073, Length=316, Percent_Identity=25.3164556962025, Blast_Score=102, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17562298, Length=299, Percent_Identity=35.7859531772575, Blast_Score=189, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17554012, Length=302, Percent_Identity=34.7682119205298, Blast_Score=176, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 34146; Mature: 34146

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTATAAAITESQFADLPNGTRLHYASAGKRGAPLMLFVHGFPEFWYEWEAQLAAFGATH
CCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCC
FAVAPDMRGFNLSSKPAAVDAYRPKFLVQDLEQFIAALGYERAIVVAHDWGGAICWNLAI
EEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEEC
QHPELVERLVIVNSPHPWVFANALLSDPAQQASSAYMNWLRQPGSEEALAANEFEKLEGF
CCHHHHHHHHEECCCCCCEEHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
FSGMGQPVAEWFTPEVRARYHAAWSQPGEGGSHGLTGGVNYYRASPLHPPTEGTAPLRID
HHCCCCHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCEEEC
QMPPEAFIVKVPTLVIWGEMDMALPKSLLNGLERFIPDMRLERIPDGTHWVVHEQPERVN
CCCCCEEEEEECEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCEEEEECCCHHHH
ALIRSFVS
HHHHHHCC
>Mature Secondary Structure
MNTATAAAITESQFADLPNGTRLHYASAGKRGAPLMLFVHGFPEFWYEWEAQLAAFGATH
CCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCC
FAVAPDMRGFNLSSKPAAVDAYRPKFLVQDLEQFIAALGYERAIVVAHDWGGAICWNLAI
EEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEEC
QHPELVERLVIVNSPHPWVFANALLSDPAQQASSAYMNWLRQPGSEEALAANEFEKLEGF
CCHHHHHHHHEECCCCCCEEHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
FSGMGQPVAEWFTPEVRARYHAAWSQPGEGGSHGLTGGVNYYRASPLHPPTEGTAPLRID
HHCCCCHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCEEEC
QMPPEAFIVKVPTLVIWGEMDMALPKSLLNGLERFIPDMRLERIPDGTHWVVHEQPERVN
CCCCCEEEEEECEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCEEEEECCCHHHH
ALIRSFVS
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]