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The map label for this gene is ygfZ [C]

Identifier: 187928513

GI number: 187928513

Start: 1516246

End: 1517286

Strand: Direct

Name: ygfZ [C]

Synonym: Rpic_1427

Alternate gene names: 187928513

Gene position: 1516246-1517286 (Clockwise)

Preceding gene: 187928506

Following gene: 187928514

Centisome position: 38.46

GC content: 65.8

Gene sequence:

>1041_bases
ATGAATGATGTCTTCCACGATTTTGTCGATACGCTGAGCTTTCCTCCGCTCGACGTGCAATTTGATGCCGCCACGCGCGG
CAGCGTGCTGTGTGCGCCGACCGATCTGGCGCGCATCGCTGTCGAAGGCGCCGATGCCGCCGAGTTCCTCCATAACCAAC
TCACCAACGCCGTGACCGGCCTGGGCCTGAACCAGGCGCGACTGGCGGGCTATTGCTCGCCCAAAGGACGGCTGCTTGCC
ACCCTGCTGGTATGGCGCCAGGCCGATACGATCGTGCTGCAGACAGACAAGCTGATCGCGCCCGCGTTGACCAAGCGCCT
GTCGATGTTCGTGCTGCGCGCCAAGGCCAAGCTGCGCCCGATGGACGAGTTCATCGCCATCGGCGTCGCCGGGCCTGACG
CGGCGGAAGCGCTGCGCGAGGCTGGTGCCGTGCTGCCTGAACCCGATACCGTCAACGCGGTGGCGCAGCAGCCTGCCACG
GTCGGCCAGCAATTCGGCGCCGTCGTCCGCCTGCCGGATGCCGGCGGCCGCCCGCGCTATCAATGGATGGTGCATGCCGA
GCACTTCCAGGACGCCTGGAAGACGCTGTCGTCGCGGCTGTCGCTGGTCGGCACCGAGGTGTGGGATTGGCTGAGCCTGC
AGGCAGGTGTGCCGCACATCACCCTGCCCACACAGGAGCAGTTCGTCCCGCAGATGGTGAACCTGGAACTGCTGGGCGGC
GTCGATTTCCGCAAGGGTTGTTATCCGGGGCAGGAAATCGTGGCACGCAGCCAGTATCGCGGCACGCTCAAGCGGCGCAT
GCAGCGCGCGCACGTCAATGCCCCCACGTCGGCCGGCGCCGAGGTCTACAGCGCAGCCGATCCGAACCAACCGTGCGGCA
TGGTGGTCAATGCAGCCATGGCGCCGGATGGCGGGACCGATCTACTCGTCGAATTGAAGCTGGACGCCCTCGACACCGTC
ATCCACCTGGCCACGCCGGACGGCCCGATGCTGACGCTGCAAGAACTGCCGTACGTCATTCCCGCTTCAGAAAACGCCTG
A

Upstream 100 bases:

>100_bases
CACCGGCGATTGCCGCACTCTTGAAATGGATAGACAGGGCACAAGCTGCCCTTCAGACAGCCCAATATAATACCGGGTCA
ATCTCAGGCCGCCCCGCACC

Downstream 100 bases:

>100_bases
TACCGCCCCCACCATGGCCGACCACCTGTTCGTCTACTTCCGCATCGCCGAGCGTGACGCTGCCAATGCCCTGCCGCGCT
GGCAGCGTTGGCTCGATACC

Product: folate-binding protein YgfZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MNDVFHDFVDTLSFPPLDVQFDAATRGSVLCAPTDLARIAVEGADAAEFLHNQLTNAVTGLGLNQARLAGYCSPKGRLLA
TLLVWRQADTIVLQTDKLIAPALTKRLSMFVLRAKAKLRPMDEFIAIGVAGPDAAEALREAGAVLPEPDTVNAVAQQPAT
VGQQFGAVVRLPDAGGRPRYQWMVHAEHFQDAWKTLSSRLSLVGTEVWDWLSLQAGVPHITLPTQEQFVPQMVNLELLGG
VDFRKGCYPGQEIVARSQYRGTLKRRMQRAHVNAPTSAGAEVYSAADPNQPCGMVVNAAMAPDGGTDLLVELKLDALDTV
IHLATPDGPMLTLQELPYVIPASENA

Sequences:

>Translated_346_residues
MNDVFHDFVDTLSFPPLDVQFDAATRGSVLCAPTDLARIAVEGADAAEFLHNQLTNAVTGLGLNQARLAGYCSPKGRLLA
TLLVWRQADTIVLQTDKLIAPALTKRLSMFVLRAKAKLRPMDEFIAIGVAGPDAAEALREAGAVLPEPDTVNAVAQQPAT
VGQQFGAVVRLPDAGGRPRYQWMVHAEHFQDAWKTLSSRLSLVGTEVWDWLSLQAGVPHITLPTQEQFVPQMVNLELLGG
VDFRKGCYPGQEIVARSQYRGTLKRRMQRAHVNAPTSAGAEVYSAADPNQPCGMVVNAAMAPDGGTDLLVELKLDALDTV
IHLATPDGPMLTLQELPYVIPASENA
>Mature_346_residues
MNDVFHDFVDTLSFPPLDVQFDAATRGSVLCAPTDLARIAVEGADAAEFLHNQLTNAVTGLGLNQARLAGYCSPKGRLLA
TLLVWRQADTIVLQTDKLIAPALTKRLSMFVLRAKAKLRPMDEFIAIGVAGPDAAEALREAGAVLPEPDTVNAVAQQPAT
VGQQFGAVVRLPDAGGRPRYQWMVHAEHFQDAWKTLSSRLSLVGTEVWDWLSLQAGVPHITLPTQEQFVPQMVNLELLGG
VDFRKGCYPGQEIVARSQYRGTLKRRMQRAHVNAPTSAGAEVYSAADPNQPCGMVVNAAMAPDGGTDLLVELKLDALDTV
IHLATPDGPMLTLQELPYVIPASENA

Specific function: Folate-binding protein involved in regulating the level of ATP-dnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication [H]

COG id: COG0354

COG function: function code R; Predicted aminomethyltransferase related to GcvT

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tRNA-modifying ygfZ family [H]

Homologues:

Organism=Escherichia coli, GI1789265, Length=320, Percent_Identity=28.75, Blast_Score=112, Evalue=4e-26,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017703
- InterPro:   IPR006222 [H]

Pfam domain/function: PF01571 GCV_T [H]

EC number: NA

Molecular weight: Translated: 37320; Mature: 37320

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDVFHDFVDTLSFPPLDVQFDAATRGSVLCAPTDLARIAVEGADAAEFLHNQLTNAVTG
CCHHHHHHHHHCCCCCCCEEECCCCCCCEEECCCHHHHEEECCCHHHHHHHHHHHHHHHC
LGLNQARLAGYCSPKGRLLATLLVWRQADTIVLQTDKLIAPALTKRLSMFVLRAKAKLRP
CCCCHHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCC
MDEFIAIGVAGPDAAEALREAGAVLPEPDTVNAVAQQPATVGQQFGAVVRLPDAGGRPRY
CCCEEEEECCCCHHHHHHHHCCCCCCCCCCHHHHHHCCHHHHHHCCCEEECCCCCCCCCE
QWMVHAEHFQDAWKTLSSRLSLVGTEVWDWLSLQAGVPHITLPTQEQFVPQMVNLELLGG
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHCEEEECC
VDFRKGCYPGQEIVARSQYRGTLKRRMQRAHVNAPTSAGAEVYSAADPNQPCGMVVNAAM
CCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCEEEEEE
APDGGTDLLVELKLDALDTVIHLATPDGPMLTLQELPYVIPASENA
CCCCCCEEEEEEEHHHHCEEEEEECCCCCEEEHHHCCEEECCCCCC
>Mature Secondary Structure
MNDVFHDFVDTLSFPPLDVQFDAATRGSVLCAPTDLARIAVEGADAAEFLHNQLTNAVTG
CCHHHHHHHHHCCCCCCCEEECCCCCCCEEECCCHHHHEEECCCHHHHHHHHHHHHHHHC
LGLNQARLAGYCSPKGRLLATLLVWRQADTIVLQTDKLIAPALTKRLSMFVLRAKAKLRP
CCCCHHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCC
MDEFIAIGVAGPDAAEALREAGAVLPEPDTVNAVAQQPATVGQQFGAVVRLPDAGGRPRY
CCCEEEEECCCCHHHHHHHHCCCCCCCCCCHHHHHHCCHHHHHHCCCEEECCCCCCCCCE
QWMVHAEHFQDAWKTLSSRLSLVGTEVWDWLSLQAGVPHITLPTQEQFVPQMVNLELLGG
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHCEEEECC
VDFRKGCYPGQEIVARSQYRGTLKRRMQRAHVNAPTSAGAEVYSAADPNQPCGMVVNAAM
CCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCEEEEEE
APDGGTDLLVELKLDALDTVIHLATPDGPMLTLQELPYVIPASENA
CCCCCCEEEEEEEHHHHCEEEEEECCCCCEEEHHHCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA