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The map label for this gene is benK [H]

Identifier: 187928455

GI number: 187928455

Start: 1466055

End: 1467374

Strand: Direct

Name: benK [H]

Synonym: Rpic_1368

Alternate gene names: 187928455

Gene position: 1466055-1467374 (Clockwise)

Preceding gene: 187928454

Following gene: 187928456

Centisome position: 37.19

GC content: 64.77

Gene sequence:

>1320_bases
ATGCGTCAGATTGACCTGCACGCAGTGGCCGACCACGCCCGGTTCGGCCGCTTCCATGCCATCACACTGTTCTGGTGCGC
GCTCATCATCATCTTTGACGGCTACGACCTTGCCATCGCGGGCATTGCACTGCCGTCCATCATGAAGGACATGGGCGTCA
CGCCCACCAGCGCCGGCTTCATGGTCAGCGCGGCACTGTTCGGCATGATGTTCGGCGCGATCTTTCTGGGCACGATTGCG
GATCGTATCGGCCGCCGCTGGGCGATTGCCGTGTGCATCGTGCTGTTCAGCGTCTTTACGGCGGCAGCGGGTTTCTCCAC
GGACCCGGTCACCTTCAGCGTGACGCGTTTCCTGGCGGGCCTCGGTATCGGCGGTGTGATGCCGAACGTCGTGGCGCAGA
TGACGGAGTACTCGCCGCGCCGGGCGCGCAGCACGCTCGTCACGCTCATGTTCAGCGGCTATTCGGTGGGCGGCATGCTG
GCGGCGCTGCTGGGCAAGGGTCTGCTGGAACACTACGGCTGGCAATCGGTGTTCATCGCGGCTGTGCTGCCCGTGCTGCT
GGTGCCGGCGATCCTGCGGTGGATGCCGGAATCGATGCCGTTCCTGCTGCGCACCGGCAAGCTCGATGCGGTGCGTGACA
TCGTGCGCCGGCTCAACCCAAACGATGCGCCTCAGCCAGGCGACACCTTCATCCTGCCCGAAGCCGATCGCGGCAACGAA
GCGCCGCTGGGCAGGCTGTTCCAGGACGGACGCGGCTTCAGCACGGCGATGTTCTGGATTGCCTTCTTCATGTGCCTGTT
CATGGTTTACGCGCTCAGCTCGTGGCTGACCAAGCTGATGGCGTCGGCGGGCTACAGCCTGGGTTCGGCGCTCACCTTTG
TGCTGGTGCTGAACTTCGGGGCCATGCTCGGCGCCATCGGCGGCGGCTGGCTGGCTGATCGCTTCAACATCAAATACGTG
CTGATGGCCATGTATGCGCTGGCGGCGGTGTCGATCGCATTGCTCGGCATCAAGACTTCAACCGAGGCGCTGTACGTGCT
GGTGGCCGTGGCCGGCGGCTGCACCATCGGCACGCAGATCGTGACGTACGCCTATGCCGGGCAGTTCTATCCGATGAGCA
TCCGCTCCACGGGCATCGGCTGGGCATCGGGCGTCGGGCGCAGCGGGGCCATCCTCGCTCCCATCGTCATCGGCATGCTG
GTGGGGATGGCGCTACCGCTGCACCACAACTTCTTCGCCATGGCTGTGCCGGCGGTGATTGCGACGATTGCCGTGGCGTT
CATCAACCACCAGCGGTCGGCCTCGGTCATCGCGCGCTGA

Upstream 100 bases:

>100_bases
AGGTTTGAAGCGCCAACAGAGCGCGCCATCAGTCGAAGAAGCCAACCCAGCATAAGAAAGGCGCTCACGCCTTCAAAAAA
AACCCCAAAGGAGACCACCC

Downstream 100 bases:

>100_bases
TCTGCCACCAGCGATGCATCCATCGAGCACGCAAACGGCCTCGCGCGGGGCGCTGTCCGATTGGTCCCTCTCGGCCGTCG
CGGCGGGGTTCCTGGCCGTG

Product: major facilitator superfamily protein

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MRQIDLHAVADHARFGRFHAITLFWCALIIIFDGYDLAIAGIALPSIMKDMGVTPTSAGFMVSAALFGMMFGAIFLGTIA
DRIGRRWAIAVCIVLFSVFTAAAGFSTDPVTFSVTRFLAGLGIGGVMPNVVAQMTEYSPRRARSTLVTLMFSGYSVGGML
AALLGKGLLEHYGWQSVFIAAVLPVLLVPAILRWMPESMPFLLRTGKLDAVRDIVRRLNPNDAPQPGDTFILPEADRGNE
APLGRLFQDGRGFSTAMFWIAFFMCLFMVYALSSWLTKLMASAGYSLGSALTFVLVLNFGAMLGAIGGGWLADRFNIKYV
LMAMYALAAVSIALLGIKTSTEALYVLVAVAGGCTIGTQIVTYAYAGQFYPMSIRSTGIGWASGVGRSGAILAPIVIGML
VGMALPLHHNFFAMAVPAVIATIAVAFINHQRSASVIAR

Sequences:

>Translated_439_residues
MRQIDLHAVADHARFGRFHAITLFWCALIIIFDGYDLAIAGIALPSIMKDMGVTPTSAGFMVSAALFGMMFGAIFLGTIA
DRIGRRWAIAVCIVLFSVFTAAAGFSTDPVTFSVTRFLAGLGIGGVMPNVVAQMTEYSPRRARSTLVTLMFSGYSVGGML
AALLGKGLLEHYGWQSVFIAAVLPVLLVPAILRWMPESMPFLLRTGKLDAVRDIVRRLNPNDAPQPGDTFILPEADRGNE
APLGRLFQDGRGFSTAMFWIAFFMCLFMVYALSSWLTKLMASAGYSLGSALTFVLVLNFGAMLGAIGGGWLADRFNIKYV
LMAMYALAAVSIALLGIKTSTEALYVLVAVAGGCTIGTQIVTYAYAGQFYPMSIRSTGIGWASGVGRSGAILAPIVIGML
VGMALPLHHNFFAMAVPAVIATIAVAFINHQRSASVIAR
>Mature_439_residues
MRQIDLHAVADHARFGRFHAITLFWCALIIIFDGYDLAIAGIALPSIMKDMGVTPTSAGFMVSAALFGMMFGAIFLGTIA
DRIGRRWAIAVCIVLFSVFTAAAGFSTDPVTFSVTRFLAGLGIGGVMPNVVAQMTEYSPRRARSTLVTLMFSGYSVGGML
AALLGKGLLEHYGWQSVFIAAVLPVLLVPAILRWMPESMPFLLRTGKLDAVRDIVRRLNPNDAPQPGDTFILPEADRGNE
APLGRLFQDGRGFSTAMFWIAFFMCLFMVYALSSWLTKLMASAGYSLGSALTFVLVLNFGAMLGAIGGGWLADRFNIKYV
LMAMYALAAVSIALLGIKTSTEALYVLVAVAGGCTIGTQIVTYAYAGQFYPMSIRSTGIGWASGVGRSGAILAPIVIGML
VGMALPLHHNFFAMAVPAVIATIAVAFINHQRSASVIAR

Specific function: Probable uptake of benzoate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI7662270, Length=234, Percent_Identity=28.2051282051282, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI24308167, Length=404, Percent_Identity=23.2673267326733, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI73695465, Length=253, Percent_Identity=28.4584980237154, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI216548223, Length=234, Percent_Identity=28.2051282051282, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI262399383, Length=173, Percent_Identity=28.3236994219653, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI24497476, Length=346, Percent_Identity=24.8554913294798, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI20070188, Length=346, Percent_Identity=24.8554913294798, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI166064021, Length=344, Percent_Identity=25, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI296080734, Length=370, Percent_Identity=23.5135135135135, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI296080719, Length=356, Percent_Identity=23.5955056179775, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI24497499, Length=356, Percent_Identity=23.5955056179775, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI296080721, Length=370, Percent_Identity=23.5135135135135, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI8923870, Length=366, Percent_Identity=24.3169398907104, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI87081723, Length=415, Percent_Identity=29.8795180722892, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1786229, Length=444, Percent_Identity=24.7747747747748, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI87082159, Length=370, Percent_Identity=29.1891891891892, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI87082231, Length=204, Percent_Identity=27.9411764705882, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI87082404, Length=407, Percent_Identity=23.5872235872236, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788074, Length=379, Percent_Identity=24.2744063324538, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI32564663, Length=402, Percent_Identity=23.3830845771144, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17560496, Length=367, Percent_Identity=21.7983651226158, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193207761, Length=376, Percent_Identity=23.6702127659574, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17559830, Length=376, Percent_Identity=23.6702127659574, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6320595, Length=194, Percent_Identity=28.8659793814433, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640198, Length=229, Percent_Identity=27.5109170305677, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24640196, Length=229, Percent_Identity=27.5109170305677, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24640200, Length=229, Percent_Identity=27.5109170305677, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI19922874, Length=433, Percent_Identity=22.6327944572748, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI19922616, Length=369, Percent_Identity=25.4742547425474, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24668440, Length=340, Percent_Identity=24.7058823529412, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46946; Mature: 46946

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: PS00120 LIPASE_SER ; PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCCHHHHCC
>Mature Secondary Structure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HHHHHHHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9294456 [H]