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The map label for this gene is catB [H]

Identifier: 187928448

GI number: 187928448

Start: 1459832

End: 1460941

Strand: Direct

Name: catB [H]

Synonym: Rpic_1361

Alternate gene names: 187928448

Gene position: 1459832-1460941 (Clockwise)

Preceding gene: 187928445

Following gene: 187928449

Centisome position: 37.03

GC content: 65.86

Gene sequence:

>1110_bases
ATGATTCGCTCGATCGAGGCAATTCTAGTGGATGTGCCCACCATCCGTCCGCACAAACTGTCCGTCGCCACCATGCACAC
GCAGACGCTCGTCCTCGTGCGAGTGTGCTGCGAAGACGGCATCGAAGGCTGGGGCGAGGCCACCACTATTGGCGGCCTCA
ACTACGGCGAAGAGAGCCCCGAGAGCATCAAGGTCAACATCGACACGCACATCGCGCCGCTGCTGATCGGCATGGAGGCG
CGCAATGTGGCGGCAGCCATGGCTCGCGTGCGCAAGACCATCCAGGGCAACCGCTTTGCCAAGTGCGCGCTGGAAACAGC
GCTGCTGGACGCGCAGGCCCGCCGGCTTGGTGTGCCGCTGTCAGAACTGCTGGGCGGCCGGCTACGCGATGCGCTGCCGG
TGGCCTGGACGCTCGCCAGTGGCGACACGAAGAAGGACATTGCCGAGGCAGAAGCGATGCTGGCTGAGCGCCGCCACCGC
ATCTTCAAGCTGAAGATCGGCTTGCGCCCGGTAGCAGACGATGTGGCCCATGTACTGGCCATCAAACGGGCGCTGGGCGA
TGCCGTGAGCGTGCGCGTGGACGTCAATCAGGCCTGGAGCGAGCTCGACGCCGCCAATGGCATCGCCGCGTTGCAGGCCG
GCGGCATCGACCTGATCGAGCAACCGGTGCGCGCAGAAAACCGCGCCGCGCTGGAGCGCCTCGCCCGCCAGTTCGCCGTG
CCGATGATGGCCGATGAGGCACTGCACGGTCCGCTGGATGCCTTCGAACTGGCGTGCAGCGCGAGCGCCGACGTCTTTGC
CGTGAAGATCGCGCAGTCCGGCGGGTTGGTTCCGGCCATGCAGGTCGCCGCCATCGCGCAGCTTGCGGGCATCAGCCTCT
ACGGCGGAACTATGCTGGAAGGGGCAGTCGGCACAGCAGCGTCGGCCCACGTGTTTTCCACCTTTGGCGAGCTGCAGTTC
GGCACCGAGCTGTTCGGCCCCTTGTTGCTCACGCAAGAACTGCTGACCGAGCCGCTGCAATACCGCGACTTCATGTTGCA
GGTGCCGACCGGCCCCGGCCTGGGCATCGAGATCGATCACGACAAGCTGGCGCGCCTGCGCCGCCAATAA

Upstream 100 bases:

>100_bases
TGGAGTATGAAACTGATACTAAATCAGTGTTGGACGTGACAATTCGCGCTGCGTAATCTGGTTCCCACGTTGATAGCAGT
TCTTCTGATACCTGGAAAAC

Downstream 100 bases:

>100_bases
CAACCGCCTTACCAAGACACCGCCAAGGAAACCACGATGCTGTTCCACGTCCGCATGGATGTCCGCCTGCCGGCCGACAT
GCCCGCCGATGTCGCCAACG

Product: muconate and chloromuconate cycloisomerase

Products: NA

Alternate protein names: Cis,cis-muconate lactonizing enzyme I; MLE; Muconate cycloisomerase I [H]

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MIRSIEAILVDVPTIRPHKLSVATMHTQTLVLVRVCCEDGIEGWGEATTIGGLNYGEESPESIKVNIDTHIAPLLIGMEA
RNVAAAMARVRKTIQGNRFAKCALETALLDAQARRLGVPLSELLGGRLRDALPVAWTLASGDTKKDIAEAEAMLAERRHR
IFKLKIGLRPVADDVAHVLAIKRALGDAVSVRVDVNQAWSELDAANGIAALQAGGIDLIEQPVRAENRAALERLARQFAV
PMMADEALHGPLDAFELACSASADVFAVKIAQSGGLVPAMQVAAIAQLAGISLYGGTMLEGAVGTAASAHVFSTFGELQF
GTELFGPLLLTQELLTEPLQYRDFMLQVPTGPGLGIEIDHDKLARLRRQ

Sequences:

>Translated_369_residues
MIRSIEAILVDVPTIRPHKLSVATMHTQTLVLVRVCCEDGIEGWGEATTIGGLNYGEESPESIKVNIDTHIAPLLIGMEA
RNVAAAMARVRKTIQGNRFAKCALETALLDAQARRLGVPLSELLGGRLRDALPVAWTLASGDTKKDIAEAEAMLAERRHR
IFKLKIGLRPVADDVAHVLAIKRALGDAVSVRVDVNQAWSELDAANGIAALQAGGIDLIEQPVRAENRAALERLARQFAV
PMMADEALHGPLDAFELACSASADVFAVKIAQSGGLVPAMQVAAIAQLAGISLYGGTMLEGAVGTAASAHVFSTFGELQF
GTELFGPLLLTQELLTEPLQYRDFMLQVPTGPGLGIEIDHDKLARLRRQ
>Mature_369_residues
MIRSIEAILVDVPTIRPHKLSVATMHTQTLVLVRVCCEDGIEGWGEATTIGGLNYGEESPESIKVNIDTHIAPLLIGMEA
RNVAAAMARVRKTIQGNRFAKCALETALLDAQARRLGVPLSELLGGRLRDALPVAWTLASGDTKKDIAEAEAMLAERRHR
IFKLKIGLRPVADDVAHVLAIKRALGDAVSVRVDVNQAWSELDAANGIAALQAGGIDLIEQPVRAENRAALERLARQFAV
PMMADEALHGPLDAFELACSASADVFAVKIAQSGGLVPAMQVAAIAQLAGISLYGGTMLEGAVGTAASAHVFSTFGELQF
GTELFGPLLLTQELLTEPLQYRDFMLQVPTGPGLGIEIDHDKLARLRRQ

Specific function: Catalyzes a syn cycloisomerization [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family [H]

Homologues:

Organism=Escherichia coli, GI87081876, Length=264, Percent_Identity=29.5454545454545, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI48994953, Length=359, Percent_Identity=23.9554317548747, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013370
- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =5.5.1.1 [H]

Molecular weight: Translated: 39468; Mature: 39468

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00606 B_KETOACYL_SYNTHASE ; PS00908 MR_MLE_1 ; PS00909 MR_MLE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRSIEAILVDVPTIRPHKLSVATMHTQTLVLVRVCCEDGIEGWGEATTIGGLNYGEESP
CCCCEEEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCC
ESIKVNIDTHIAPLLIGMEARNVAAAMARVRKTIQGNRFAKCALETALLDAQARRLGVPL
CEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCH
SELLGGRLRDALPVAWTLASGDTKKDIAEAEAMLAERRHRIFKLKIGLRPVADDVAHVLA
HHHHCCHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHH
IKRALGDAVSVRVDVNQAWSELDAANGIAALQAGGIDLIEQPVRAENRAALERLARQFAV
HHHHHCCEEEEEEEHHHHHHHHHHCCCCCEEECCCHHHHHCCCCCCHHHHHHHHHHHHCC
PMMADEALHGPLDAFELACSASADVFAVKIAQSGGLVPAMQVAAIAQLAGISLYGGTMLE
CHHHHHHHCCCHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCEEECCHHHH
GAVGTAASAHVFSTFGELQFGTELFGPLLLTQELLTEPLQYRDFMLQVPTGPGLGIEIDH
CCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHCCEEEECCCCCCCCEEECH
DKLARLRRQ
HHHHHHHCC
>Mature Secondary Structure
MIRSIEAILVDVPTIRPHKLSVATMHTQTLVLVRVCCEDGIEGWGEATTIGGLNYGEESP
CCCCEEEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCC
ESIKVNIDTHIAPLLIGMEARNVAAAMARVRKTIQGNRFAKCALETALLDAQARRLGVPL
CEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCH
SELLGGRLRDALPVAWTLASGDTKKDIAEAEAMLAERRHRIFKLKIGLRPVADDVAHVLA
HHHHCCHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHH
IKRALGDAVSVRVDVNQAWSELDAANGIAALQAGGIDLIEQPVRAENRAALERLARQFAV
HHHHHCCEEEEEEEHHHHHHHHHHCCCCCEEECCCHHHHHCCCCCCHHHHHHHHHHHHCC
PMMADEALHGPLDAFELACSASADVFAVKIAQSGGLVPAMQVAAIAQLAGISLYGGTMLE
CHHHHHHHCCCHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCEEECCHHHH
GAVGTAASAHVFSTFGELQFGTELFGPLLLTQELLTEPLQYRDFMLQVPTGPGLGIEIDH
CCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHCCEEEECCCCCCCCEEECH
DKLARLRRQ
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8125318 [H]