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The map label for this gene is fabZ [H]

Identifier: 187928378

GI number: 187928378

Start: 1385592

End: 1386095

Strand: Direct

Name: fabZ [H]

Synonym: Rpic_1289

Alternate gene names: 187928378

Gene position: 1385592-1386095 (Clockwise)

Preceding gene: 187928377

Following gene: 187928379

Centisome position: 35.14

GC content: 60.12

Gene sequence:

>504_bases
ATGACCGAAGCAACGAATGCGACGAGCGCGACCCCCAGCGTCGTCAGCGATTTCAACATCAAGAAGATTCTCGACCTGCT
GCCGCATCGCTACCCGATGCTGCTGGTTGACCGCGTGATCTCGCTGGAGCCGCGCAAGTCGATTACGGCCATCAAGAACG
TGACGTTCAACGAGCCGTTCTTCAACGGGCACTTCCCCGGCCATCCGGTGATGCCCGGCGTGCTGATGCTCGAAGCGCTT
GCGCAAACCGCTGCGCTGTTGACCTTCGGCGAGGCCGATCACGAGCGCAAGGAAAACCAGCTCTACCTGTTCGTGAGCAT
TGACGGTGCACGCTTCAAGCGCCAGGTGACGCCGGGCGACCAACTCGTGATGACGGCCGAACTGCTGCGCTCGAAGAGCG
GTATGTGGAAGTTCAAGGTGTACGGCAAGGTTGACGGTGAAGTCGCCGTGGAAGCCGAAATCATGTGTGCCGTGCGCGAA
GACAAGTCCAAGGGCGAGGCATGA

Upstream 100 bases:

>100_bases
GCGACTGGGAGCGTAACGCGGCCATCGTCCGAGGCCTGACGCGCATGCGCGAACGGTTGCAACAACTGGAACAGCGGGTC
AAAGACCTGCAGCAACAATC

Downstream 100 bases:

>100_bases
CGCAAGCACAGAAGATCCATCCGACCGCGCAGATCGATCCGAATGCCGAACTGGATTCGAGCGTCGAGATCGGCGCGTTT
ACGGTCGTGGGCCCGAATGT

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 167; Mature: 166

Protein sequence:

>167_residues
MTEATNATSATPSVVSDFNIKKILDLLPHRYPMLLVDRVISLEPRKSITAIKNVTFNEPFFNGHFPGHPVMPGVLMLEAL
AQTAALLTFGEADHERKENQLYLFVSIDGARFKRQVTPGDQLVMTAELLRSKSGMWKFKVYGKVDGEVAVEAEIMCAVRE
DKSKGEA

Sequences:

>Translated_167_residues
MTEATNATSATPSVVSDFNIKKILDLLPHRYPMLLVDRVISLEPRKSITAIKNVTFNEPFFNGHFPGHPVMPGVLMLEAL
AQTAALLTFGEADHERKENQLYLFVSIDGARFKRQVTPGDQLVMTAELLRSKSGMWKFKVYGKVDGEVAVEAEIMCAVRE
DKSKGEA
>Mature_166_residues
TEATNATSATPSVVSDFNIKKILDLLPHRYPMLLVDRVISLEPRKSITAIKNVTFNEPFFNGHFPGHPVMPGVLMLEALA
QTAALLTFGEADHERKENQLYLFVSIDGARFKRQVTPGDQLVMTAELLRSKSGMWKFKVYGKVDGEVAVEAEIMCAVRED
KSKGEA

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=139, Percent_Identity=50.3597122302158, Blast_Score=152, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 18568; Mature: 18437

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEATNATSATPSVVSDFNIKKILDLLPHRYPMLLVDRVISLEPRKSITAIKNVTFNEPF
CCCCCCCCCCCCHHHCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCC
FNGHFPGHPVMPGVLMLEALAQTAALLTFGEADHERKENQLYLFVSIDGARFKRQVTPGD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCHHEEEECCCCC
QLVMTAELLRSKSGMWKFKVYGKVDGEVAVEAEIMCAVREDKSKGEA
HHHHHHHHHHCCCCCEEEEEEEECCCCEEEEEEEEEEEECCCCCCCC
>Mature Secondary Structure 
TEATNATSATPSVVSDFNIKKILDLLPHRYPMLLVDRVISLEPRKSITAIKNVTFNEPF
CCCCCCCCCCCHHHCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCC
FNGHFPGHPVMPGVLMLEALAQTAALLTFGEADHERKENQLYLFVSIDGARFKRQVTPGD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCHHEEEECCCCC
QLVMTAELLRSKSGMWKFKVYGKVDGEVAVEAEIMCAVREDKSKGEA
HHHHHHHHHHCCCCCEEEEEEEECCCCEEEEEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]